Rattus norvegicus

177 known processes

Irf1

interferon regulatory factor 1

Irf1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.454
neuron differentiation GO:0030182 368 0.336
nucleic acid templated transcription GO:0097659 379 0.245
regulation of nucleic acid templated transcription GO:1903506 380 0.239
regulation of transcription dna templated GO:0006355 374 0.236
cellular component assembly GO:0022607 360 0.228
positive regulation of multicellular organismal process GO:0051240 387 0.217
regulation of multicellular organismal development GO:2000026 376 0.209
cellular response to stress GO:0033554 269 0.207
regulation of satellite cell proliferation GO:0014842 1 0.205
regulation of ion transport GO:0043269 245 0.188
regulation of rna biosynthetic process GO:2001141 381 0.187
macromolecular complex assembly GO:0065003 273 0.179
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.178
rna biosynthetic process GO:0032774 380 0.163
negative regulation of rna metabolic process GO:0051253 123 0.162
behavior GO:0007610 205 0.160
antigen processing and presentation GO:0019882 2 0.159
protein complex biogenesis GO:0070271 263 0.153
neuron death GO:0070997 127 0.145
cellular component biogenesis GO:0044085 368 0.141
jak stat cascade GO:0007259 26 0.140
metal ion transport GO:0030001 289 0.140
cellular response to cytokine stimulus GO:0071345 127 0.132
aging GO:0007568 241 0.123
macromolecular complex subunit organization GO:0043933 339 0.119
regulation of phosphate metabolic process GO:0019220 349 0.113
regulation of cellular component organization GO:0051128 368 0.112
cellular response to biotic stimulus GO:0071216 59 0.111
protein transport GO:0015031 132 0.106
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.105
protein localization GO:0008104 191 0.105
regulation of organelle organization GO:0033043 80 0.105
response to heat GO:0009408 60 0.104
response to extracellular stimulus GO:0009991 380 0.104
cellular amino acid metabolic process GO:0006520 107 0.104
cation homeostasis GO:0055080 195 0.104
positive regulation of cellular component organization GO:0051130 200 0.104
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.101
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.100
response to decreased oxygen levels GO:0036293 237 0.098
macromolecule localization GO:0033036 252 0.097
positive regulation of signal transduction GO:0009967 175 0.094
cell projection organization GO:0030030 302 0.092
tolerance induction dependent upon immune response GO:0002461 2 0.092
response to nutrient levels GO:0031667 370 0.090
tissue development GO:0009888 252 0.090
immune system process GO:0002376 204 0.090
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.088
regulation of neurogenesis GO:0050767 247 0.087
single organism carbohydrate metabolic process GO:0044723 118 0.087
carbohydrate metabolic process GO:0005975 130 0.086
protein complex assembly GO:0006461 263 0.086
protein complex subunit organization GO:0071822 302 0.083
cellular response to endogenous stimulus GO:0071495 377 0.083
regulation of cell proliferation GO:0042127 359 0.083
regulation of signal transduction GO:0009966 318 0.082
innate immune response GO:0045087 35 0.081
establishment of protein localization GO:0045184 141 0.080
multicellular organism reproduction GO:0032504 233 0.079
response to amine GO:0014075 46 0.077
carbohydrate derivative metabolic process GO:1901135 346 0.076
positive regulation of rna metabolic process GO:0051254 203 0.076
positive regulation of tolerance induction GO:0002645 1 0.075
carbohydrate derivative biosynthetic process GO:1901137 124 0.075
head development GO:0060322 247 0.075
cytokine mediated signaling pathway GO:0019221 43 0.075
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.074
positive regulation of cellular biosynthetic process GO:0031328 295 0.073
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.073
cellular response to peptide hormone stimulus GO:0071375 120 0.072
negative regulation of transport GO:0051051 136 0.072
cellular ion homeostasis GO:0006873 184 0.071
secretion GO:0046903 307 0.071
positive regulation of biosynthetic process GO:0009891 319 0.070
rna metabolic process GO:0016070 406 0.070
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.070
transcription dna templated GO:0006351 377 0.070
regulation of cell development GO:0060284 263 0.069
immune response GO:0006955 104 0.068
regulation of cell differentiation GO:0045595 320 0.068
response to amphetamine GO:0001975 25 0.064
negative regulation of metabolic process GO:0009892 331 0.064
cation transport GO:0006812 382 0.064
regulation of rna metabolic process GO:0051252 391 0.064
regulation of cellular localization GO:0060341 263 0.063
regulation of protein import into nucleus GO:0042306 24 0.063
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.062
positive regulation of cell differentiation GO:0045597 217 0.062
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.062
nucleoside phosphate metabolic process GO:0006753 283 0.062
monovalent inorganic cation transport GO:0015672 172 0.062
regulation of tolerance induction to nonself antigen GO:0002655 1 0.061
regulation of protein transport GO:0051223 68 0.061
amide biosynthetic process GO:0043604 10 0.060
regulation of nucleocytoplasmic transport GO:0046822 28 0.059
negative regulation of cellular metabolic process GO:0031324 281 0.059
positive regulation of nucleic acid templated transcription GO:1903508 197 0.059
single organism biosynthetic process GO:0044711 342 0.058
regulation of programmed cell death GO:0043067 341 0.058
positive regulation of signaling GO:0023056 270 0.058
epithelial cell differentiation involved in kidney development GO:0035850 3 0.058
regulation of mesenchymal cell proliferation GO:0010464 4 0.057
cellular response to organic cyclic compound GO:0071407 202 0.056
negative regulation of biosynthetic process GO:0009890 168 0.055
positive regulation of response to stimulus GO:0048584 285 0.055
carboxylic acid transport GO:0046942 115 0.055
cellular response to tumor necrosis factor GO:0071356 46 0.054
regulation of protein targeting GO:1903533 28 0.053
organelle organization GO:0006996 266 0.053
regulation of phosphorus metabolic process GO:0051174 349 0.053
single organism reproductive process GO:0044702 297 0.052
fat soluble vitamin biosynthetic process GO:0042362 2 0.052
positive regulation of nervous system development GO:0051962 178 0.051
enzyme linked receptor protein signaling pathway GO:0007167 116 0.051
positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 0.051
regulation of immune system process GO:0002682 123 0.050
regulation of cellular component biogenesis GO:0044087 86 0.049
response to inorganic substance GO:0010035 377 0.049
reproduction GO:0000003 245 0.049
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation GO:1902728 1 0.049
cellular response to lipid GO:0071396 201 0.049
peptide biosynthetic process GO:0043043 3 0.049
vitamin d metabolic process GO:0042359 4 0.049
positive regulation of rna biosynthetic process GO:1902680 197 0.049
chemical homeostasis GO:0048878 292 0.048
mitotic spindle organization GO:0007052 2 0.048
cytoskeleton organization GO:0007010 111 0.047
negative regulation of cell communication GO:0010648 158 0.047
homeostatic process GO:0042592 331 0.046
response to transition metal nanoparticle GO:1990267 122 0.046
negative regulation of cellular biosynthetic process GO:0031327 161 0.046
neuron projection development GO:0031175 273 0.046
positive regulation of protein transport GO:0051222 41 0.046
t cell tolerance induction GO:0002517 3 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.045
response to peptide hormone GO:0043434 278 0.045
regulation of neuron differentiation GO:0045664 208 0.045
response to mechanical stimulus GO:0009612 134 0.044
reproductive process GO:0022414 372 0.044
reactive oxygen species biosynthetic process GO:1903409 8 0.044
potassium ion transport GO:0006813 97 0.044
sodium ion transport GO:0006814 82 0.044
programmed cell death GO:0012501 392 0.043
response to amino acid GO:0043200 75 0.043
positive regulation of cell development GO:0010720 176 0.043
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.042
cellular response to iron ion starvation GO:0010106 1 0.042
d amino acid transport GO:0042940 1 0.042
purine containing compound metabolic process GO:0072521 253 0.042
positive regulation of neurogenesis GO:0050769 165 0.041
response to corticosteroid GO:0031960 235 0.041
multi organism reproductive process GO:0044703 262 0.041
ribose phosphate metabolic process GO:0019693 235 0.041
cellular response to molecule of bacterial origin GO:0071219 56 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.041
neuron development GO:0048666 286 0.041
response to bacterium GO:0009617 200 0.040
regulation of apoptotic process GO:0042981 335 0.040
anatomical structure morphogenesis GO:0009653 298 0.040
embryonic pattern specification GO:0009880 1 0.039
response to oxygen levels GO:0070482 265 0.039
vitamin biosynthetic process GO:0009110 3 0.039
brain development GO:0007420 247 0.039
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.039
response to metal ion GO:0010038 253 0.039
negative regulation of gene expression GO:0010629 199 0.038
organ regeneration GO:0031100 101 0.038
cellular response to nitrogen compound GO:1901699 210 0.038
positive regulation of transcription dna templated GO:0045893 197 0.037
intracellular signal transduction GO:0035556 314 0.037
cell cell signaling GO:0007267 335 0.037
regulation of intracellular signal transduction GO:1902531 218 0.037
negative regulation of transcription dna templated GO:0045892 116 0.037
cellular macromolecule localization GO:0070727 122 0.037
positive regulation of gene expression GO:0010628 244 0.037
positive regulation of cell communication GO:0010647 271 0.036
multicellular organismal reproductive process GO:0048609 233 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.036
cellular catabolic process GO:0044248 295 0.036
protein phosphorylation GO:0006468 345 0.035
cellular protein localization GO:0034613 122 0.035
purine ribonucleotide metabolic process GO:0009150 227 0.035
response to hypoxia GO:0001666 231 0.035
central nervous system development GO:0007417 311 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.035
negative regulation of nucleic acid templated transcription GO:1903507 117 0.035
negative regulation of rna biosynthetic process GO:1902679 118 0.035
defense response GO:0006952 194 0.034
developmental process involved in reproduction GO:0003006 159 0.034
positive regulation of cell proliferation GO:0008284 249 0.034
single organism nuclear import GO:1902593 35 0.034
secretion by cell GO:0032940 248 0.034
axis specification GO:0009798 4 0.034
response to purine containing compound GO:0014074 126 0.034
amide transport GO:0042886 105 0.034
modification dependent macromolecule catabolic process GO:0043632 14 0.033
inflammatory response GO:0006954 150 0.033
negative regulation of developmental process GO:0051093 125 0.033
protein oligomerization GO:0051259 191 0.033
immune effector process GO:0002252 53 0.031
reactive nitrogen species metabolic process GO:2001057 1 0.031
cell morphogenesis GO:0000902 142 0.031
sexual reproduction GO:0019953 148 0.031
regulation of protein complex assembly GO:0043254 33 0.031
positive regulation of humoral immune response GO:0002922 2 0.031
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003340 2 0.031
response to molecule of bacterial origin GO:0002237 194 0.031
intracellular receptor signaling pathway GO:0030522 35 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
cellular response to organonitrogen compound GO:0071417 197 0.030
cytoplasmic transport GO:0016482 115 0.030
regulation of cell migration GO:0030334 128 0.030
nuclear import GO:0051170 35 0.029
proteolysis GO:0006508 175 0.029
cellular response to peptide GO:1901653 133 0.029
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 1 0.029
positive regulation of immune system process GO:0002684 90 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
regulation of locomotion GO:0040012 148 0.029
response to alkaloid GO:0043279 132 0.029
positive regulation of immune response GO:0050778 42 0.029
response to molecule of fungal origin GO:0002238 3 0.029
cellular chemical homeostasis GO:0055082 247 0.029
regulation of reactive oxygen species metabolic process GO:2000377 26 0.028
single organism organelle organization GO:1902589 180 0.028
regulation of cellular component movement GO:0051270 150 0.027
regulation of protein kinase activity GO:0045859 105 0.027
negative regulation of metanephros development GO:0072217 2 0.027
regulation of neutrophil migration GO:1902622 6 0.027
ion homeostasis GO:0050801 212 0.027
cellular response to insulin stimulus GO:0032869 81 0.027
nucleocytoplasmic transport GO:0006913 48 0.027
rhythmic process GO:0048511 156 0.027
positive regulation of protein phosphorylation GO:0001934 135 0.027
positive regulation of developmental process GO:0051094 283 0.027
ubiquitin dependent protein catabolic process GO:0006511 14 0.027
response to wounding GO:0009611 254 0.026
cellular response to nutrient levels GO:0031669 60 0.026
intracellular transport GO:0046907 185 0.026
regulation of sodium ion transport GO:0002028 21 0.026
apoptotic process GO:0006915 381 0.026
regulation of epithelial cell differentiation involved in kidney development GO:2000696 1 0.026
regulation of cell projection organization GO:0031344 175 0.026
positive regulation of organelle organization GO:0010638 48 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
regulation of neuron projection development GO:0010975 161 0.025
maintenance of location GO:0051235 17 0.025
neurological system process GO:0050877 219 0.025
negative regulation of innate immune response GO:0045824 4 0.025
cellular homeostasis GO:0019725 252 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 13 0.025
amine metabolic process GO:0009308 38 0.025
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
dendrite development GO:0016358 72 0.025
regulation of protein localization GO:0032880 81 0.025
g protein coupled receptor signaling pathway GO:0007186 242 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
response to radiation GO:0009314 137 0.024
regulation of metal ion transport GO:0010959 118 0.024
cellular response to reactive oxygen species GO:0034614 55 0.024
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.024
response to toxic substance GO:0009636 133 0.024
organophosphate metabolic process GO:0019637 370 0.024
calcium ion transport GO:0006816 131 0.024
negative regulation of cell proliferation GO:0008285 119 0.024
natural killer cell mediated cytotoxicity GO:0042267 6 0.023
tolerance induction to nonself antigen GO:0002462 2 0.023
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.023
oligopeptide transport GO:0006857 4 0.023
regulation of actin cytoskeleton organization GO:0032956 30 0.023
divalent metal ion transport GO:0070838 132 0.023
response to cytokine GO:0034097 215 0.023
anterior posterior pattern specification GO:0009952 1 0.023
immune system development GO:0002520 41 0.023
regulation of phosphorylation GO:0042325 248 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
organonitrogen compound biosynthetic process GO:1901566 167 0.023
positive regulation of transport GO:0051050 245 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
embryonic axis specification GO:0000578 1 0.022
nucleotide metabolic process GO:0009117 279 0.022
regulation of neuron death GO:1901214 115 0.022
spindle organization GO:0007051 2 0.022
actin filament based process GO:0030029 86 0.022
catabolic process GO:0009056 351 0.022
viral transcription GO:0019083 2 0.022
olfactory learning GO:0008355 1 0.022
response to ethanol GO:0045471 162 0.022
response to camp GO:0051591 91 0.021
positive regulation of intracellular signal transduction GO:1902533 138 0.021
response to biotic stimulus GO:0009607 226 0.021
response to estradiol GO:0032355 164 0.021
sequestering of calcium ion GO:0051208 8 0.021
regulation of system process GO:0044057 208 0.021
regulation of metanephros development GO:0072215 4 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
lipid storage GO:0019915 1 0.021
response to fungus GO:0009620 8 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
anion transport GO:0006820 178 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
regulation of molecular function GO:0065009 398 0.021
liver development GO:0001889 90 0.021
regulation of behavior GO:0050795 61 0.021
response to reactive oxygen species GO:0000302 120 0.021
ras protein signal transduction GO:0007265 29 0.021
positive regulation of leukocyte migration GO:0002687 21 0.020
protein secretion GO:0009306 34 0.020
cellular response to lipopolysaccharide GO:0071222 55 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
cognition GO:0050890 92 0.020
taxis GO:0042330 67 0.020
regulation of transferase activity GO:0051338 123 0.020
positive regulation of cytoplasmic transport GO:1903651 32 0.020
protein localization to organelle GO:0033365 57 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
cellular response to external stimulus GO:0071496 118 0.020
divalent inorganic cation homeostasis GO:0072507 165 0.020
negative regulation of signal transduction GO:0009968 83 0.020
regulation of smooth muscle cell proliferation GO:0048660 75 0.020
sensory organ development GO:0007423 74 0.020
cellular response to dna damage stimulus GO:0006974 19 0.020
skeletal muscle satellite cell proliferation GO:0014841 1 0.020
metal ion homeostasis GO:0055065 186 0.020
i kappab kinase nf kappab signaling GO:0007249 19 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
regulation of cell killing GO:0031341 12 0.019
learning or memory GO:0007611 90 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.019
nitrogen compound transport GO:0071705 229 0.019
acute phase response GO:0006953 20 0.019
cellular protein catabolic process GO:0044257 19 0.019
regulation of nervous system development GO:0051960 264 0.019
gland development GO:0048732 155 0.019
regulation of kinase activity GO:0043549 117 0.019
adaptive immune response GO:0002250 14 0.019
cellular response to extracellular stimulus GO:0031668 73 0.019
regulation of immune response GO:0050776 55 0.019
regulation of calcium ion transport GO:0051924 77 0.019
negative regulation of signaling GO:0023057 157 0.019
female sex differentiation GO:0046660 59 0.019
regulation of circadian sleep wake cycle sleep GO:0045187 18 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
cellular macromolecule catabolic process GO:0044265 29 0.018
response to carbohydrate GO:0009743 183 0.018
protein targeting to nucleus GO:0044744 35 0.018
erbb signaling pathway GO:0038127 23 0.018
regulation of intracellular transport GO:0032386 65 0.018
biological adhesion GO:0022610 110 0.018
wound healing GO:0042060 122 0.018
regeneration GO:0031099 163 0.018
carboxylic acid metabolic process GO:0019752 289 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
metanephric renal vesicle morphogenesis GO:0072283 3 0.018
regulation of leukocyte migration GO:0002685 24 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.017
granulocyte chemotaxis GO:0071621 15 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
regulation of natural killer cell mediated immunity GO:0002715 6 0.017
macromolecule catabolic process GO:0009057 58 0.017
regulation of tolerance induction GO:0002643 2 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
cellular component morphogenesis GO:0032989 155 0.017
regulation of establishment of protein localization GO:0070201 69 0.017
response to interferon gamma GO:0034341 20 0.017
response to acid chemical GO:0001101 222 0.017
response to starvation GO:0042594 59 0.017
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.017
nucleoside metabolic process GO:0009116 179 0.017
negative regulation of nervous system development GO:0051961 79 0.017
single organism behavior GO:0044708 130 0.017
hepaticobiliary system development GO:0061008 90 0.016
regulation of anion transport GO:0044070 43 0.016
gonad development GO:0008406 104 0.016
organic acid transport GO:0015849 116 0.016
regulation of protein metabolic process GO:0051246 289 0.016
protein import into nucleus GO:0006606 35 0.016
protein ubiquitination GO:0016567 28 0.016
negative regulation of protein phosphorylation GO:0001933 44 0.016
positive regulation of nucleotide metabolic process GO:0045981 91 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.016
calcium ion homeostasis GO:0055074 162 0.016
cytokine biosynthetic process GO:0042089 3 0.016
intracellular protein transport GO:0006886 79 0.016
regulation of chemotaxis GO:0050920 29 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
response to hydrogen peroxide GO:0042542 89 0.016
single organism cellular localization GO:1902580 102 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
response to organophosphorus GO:0046683 102 0.016
positive regulation of response to external stimulus GO:0032103 51 0.016
cellular protein complex assembly GO:0043623 44 0.016
regulation of protein serine threonine kinase activity GO:0071900 64 0.016
regulation of response to external stimulus GO:0032101 106 0.016
regulation of anatomical structure size GO:0090066 135 0.016
activation of cysteine type endopeptidase activity GO:0097202 4 0.016
regulation of catalytic activity GO:0050790 304 0.015
sequestering of metal ion GO:0051238 9 0.015
memory GO:0007613 54 0.015
glycosaminoglycan biosynthetic process GO:0006024 4 0.015
positive regulation of secretion GO:0051047 140 0.015
response to ketone GO:1901654 182 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
negative regulation of molecular function GO:0044092 133 0.015
cellular response to interleukin 1 GO:0071347 37 0.015
cellular macromolecular complex assembly GO:0034622 58 0.015
regulation of cellular extravasation GO:0002691 2 0.015
salivary gland morphogenesis GO:0007435 1 0.015
negative regulation of metanephric nephron tubule epithelial cell differentiation GO:0072308 1 0.015
positive regulation of catabolic process GO:0009896 78 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 1 0.015
dna metabolic process GO:0006259 96 0.015
histamine secretion involved in inflammatory response GO:0002441 3 0.015
response to insulin GO:0032868 133 0.015
development of primary sexual characteristics GO:0045137 107 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
cellular ketone metabolic process GO:0042180 51 0.014
mesoderm development GO:0007498 2 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.014
positive regulation of chemotaxis GO:0050921 23 0.014
positive regulation of chemokine production GO:0032722 4 0.014
antigen processing and presentation of peptide antigen GO:0048002 2 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
modification dependent protein catabolic process GO:0019941 14 0.014
peptidyl tyrosine phosphorylation GO:0018108 72 0.014
negative regulation of protein import into nucleus translocation GO:0033159 1 0.014
positive regulation of ion transport GO:0043270 94 0.014
negative regulation of kidney development GO:0090185 2 0.014
response to peptide GO:1901652 292 0.014
alcohol biosynthetic process GO:0046165 38 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
interleukin 12 production GO:0032615 3 0.014
syncytium formation by plasma membrane fusion GO:0000768 3 0.014
b cell mediated immunity GO:0019724 4 0.014
kidney mesenchyme development GO:0072074 2 0.014
mesenchymal to epithelial transition GO:0060231 3 0.014
positive regulation of cytoskeleton organization GO:0051495 26 0.013
protein targeting GO:0006605 61 0.013
muscle structure development GO:0061061 87 0.013
single organism intracellular transport GO:1902582 166 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
protein localization to nucleus GO:0034504 39 0.013
metanephric nephron tubule epithelial cell differentiation GO:0072257 1 0.013
response to external biotic stimulus GO:0043207 221 0.013
protein heterooligomerization GO:0051291 89 0.013
establishment of organelle localization GO:0051656 37 0.013
positive regulation of molecular function GO:0044093 230 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
insulin receptor signaling pathway GO:0008286 24 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
regulation of nitric oxide biosynthetic process GO:0045428 20 0.013
cellular response to starvation GO:0009267 27 0.013
organic anion transport GO:0015711 132 0.013
positive regulation of locomotion GO:0040017 102 0.013
positive regulation of cell migration GO:0030335 96 0.013
vitamin d biosynthetic process GO:0042368 2 0.013
positive regulation of lymphocyte migration GO:2000403 1 0.013
regulation of interferon gamma production GO:0032649 3 0.013
cellular amine metabolic process GO:0044106 38 0.013
regulation of immune effector process GO:0002697 32 0.013
eye development GO:0001654 50 0.013
glycoprotein biosynthetic process GO:0009101 19 0.013
regulation of nf kappab import into nucleus GO:0042345 5 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
antibiotic transport GO:0042891 2 0.012
positive regulation of leukocyte chemotaxis GO:0002690 10 0.012
positive regulation of protein polymerization GO:0032273 10 0.012
regulation of adaptive immune response GO:0002819 8 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
female gonad development GO:0008585 53 0.012
amino acid transport GO:0006865 70 0.012
protein modification by small protein conjugation or removal GO:0070647 35 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of satellite cell proliferation GO:1902724 1 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012

Irf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.022
gastrointestinal system cancer DOID:3119 0 0.020
organ system cancer DOID:0050686 0 0.020
liver cancer DOID:3571 0 0.020
primary immunodeficiency disease DOID:612 0 0.013
immune system disease DOID:2914 0 0.013
disease of anatomical entity DOID:7 0 0.013
severe combined immunodeficiency DOID:627 0 0.012
combined t cell and b cell immunodeficiency DOID:628 0 0.012