Rattus norvegicus

0 known processes

Irf7

interferon regulatory factor 7

(Aliases: MGC125013)

Irf7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral genome replication GO:0045071 1 0.994
response to cytokine GO:0034097 215 0.711
Rat
response to exogenous dsrna GO:0043330 3 0.675
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.614
negative regulation of kidney development GO:0090185 2 0.568
positive regulation of tolerance induction GO:0002645 1 0.502
antigen processing and presentation of endogenous antigen GO:0019883 1 0.473
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.472
regulation of tolerance induction to nonself antigen GO:0002655 1 0.451
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003340 2 0.331
viral genome replication GO:0019079 2 0.240
cellular response to iron ion starvation GO:0010106 1 0.196
negative regulation of viral process GO:0048525 4 0.187
response to virus GO:0009615 17 0.163
purine containing compound biosynthetic process GO:0072522 85 0.155
response to other organism GO:0051707 220 0.141
nucleotide metabolic process GO:0009117 279 0.136
regulation of mesenchymal cell proliferation GO:0010464 4 0.131
purine nucleotide biosynthetic process GO:0006164 83 0.124
mesenchymal cell differentiation involved in renal system development GO:2001012 1 0.107
regulation of satellite cell proliferation GO:0014842 1 0.106
female pregnancy GO:0007565 122 0.104
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.103
response to biotic stimulus GO:0009607 226 0.103
metanephric nephron tubule epithelial cell differentiation GO:0072257 1 0.100
response to external biotic stimulus GO:0043207 221 0.098
antigen processing and presentation GO:0019882 2 0.098
positive regulation of skeletal muscle cell proliferation GO:0014858 2 0.097
regulation of metanephros development GO:0072215 4 0.096
metanephric mesenchymal cell differentiation GO:0072162 1 0.095
protection from natural killer cell mediated cytotoxicity GO:0042270 2 0.094
tolerance induction to nonself antigen GO:0002462 2 0.090
ribonucleotide metabolic process GO:0009259 231 0.089
mammary gland involution GO:0060056 5 0.087
positive regulation of t cell mediated cytotoxicity GO:0001916 4 0.083
mesenchymal cell differentiation involved in kidney development GO:0072161 1 0.083
tolerance induction dependent upon immune response GO:0002461 2 0.079
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.077
nucleoside phosphate biosynthetic process GO:1901293 102 0.075
multi organism reproductive process GO:0044703 262 0.074
Rat
negative regulation of metanephros development GO:0072217 2 0.074
response to dsrna GO:0043331 9 0.072
Rat
mesenchymal to epithelial transition GO:0060231 3 0.071
response to nutrient levels GO:0031667 370 0.071
positive regulation of tolerance induction to nonself antigen GO:0002657 1 0.068
reproductive process GO:0022414 372 0.066
Rat
regulation of natural killer cell mediated immunity GO:0002715 6 0.066
nucleobase containing small molecule metabolic process GO:0055086 316 0.064
positive regulation of growth factor dependent skeletal muscle satellite cell proliferation GO:1902728 1 0.063
regulation of atp biosynthetic process GO:2001169 2 0.063
organophosphate metabolic process GO:0019637 370 0.062
hepaticobiliary system development GO:0061008 90 0.061
regulation of purine nucleotide metabolic process GO:1900542 115 0.060
pyrimidine deoxyribonucleotide biosynthetic process GO:0009221 5 0.059
regulation of hydrogen peroxide biosynthetic process GO:0010728 2 0.058
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 2 0.055
liver development GO:0001889 90 0.054
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 1 0.052
positive regulation of homotypic cell cell adhesion GO:0034112 2 0.051
response to estrogen GO:0043627 232 0.049
response to estradiol GO:0032355 164 0.047
t cell tolerance induction GO:0002517 3 0.046
metanephric renal vesicle morphogenesis GO:0072283 3 0.044
organonitrogen compound biosynthetic process GO:1901566 167 0.043
circulatory system process GO:0003013 183 0.042
purine ribonucleotide biosynthetic process GO:0009152 81 0.042
organophosphate biosynthetic process GO:0090407 143 0.041
negative regulation of metanephric nephron tubule epithelial cell differentiation GO:0072308 1 0.041
2 deoxyribonucleotide biosynthetic process GO:0009265 6 0.040
single organism biosynthetic process GO:0044711 342 0.038
nucleoside monophosphate metabolic process GO:0009123 93 0.036
gland development GO:0048732 155 0.035
response to starvation GO:0042594 59 0.034
regulation of nucleotide biosynthetic process GO:0030808 47 0.034
renal vesicle morphogenesis GO:0072077 4 0.034
regulation of viral genome replication GO:0045069 2 0.034
immune response GO:0006955 104 0.033
Human
regulation of phosphate metabolic process GO:0019220 349 0.033
Rat
epithelial cell differentiation involved in kidney development GO:0035850 3 0.033
nucleotide biosynthetic process GO:0009165 98 0.033
positive regulation of erythrocyte aggregation GO:0034120 1 0.033
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.033
negative regulation of hydrogen peroxide metabolic process GO:0010727 2 0.032
chemical homeostasis GO:0048878 292 0.031
cellular response to external stimulus GO:0071496 118 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
Human Rat
neuron projection development GO:0031175 273 0.030
purine containing compound metabolic process GO:0072521 253 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
ribonucleoside monophosphate catabolic process GO:0009158 55 0.029
regulation of homotypic cell cell adhesion GO:0034110 4 0.029
purine nucleoside monophosphate metabolic process GO:0009126 84 0.029
reproduction GO:0000003 245 0.028
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.027
purine nucleotide metabolic process GO:0006163 229 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
Rat
regulation of neuron projection development GO:0010975 161 0.026
multicellular organism reproduction GO:0032504 233 0.026
positive regulation of nucleoside metabolic process GO:0045979 55 0.026
metanephric mesenchymal cell proliferation involved in metanephros development GO:0072136 1 0.026
cellular response to oxygen containing compound GO:1901701 386 0.025
Rat
amine metabolic process GO:0009308 38 0.025
regulation of tolerance induction GO:0002643 2 0.025
ribonucleotide biosynthetic process GO:0009260 85 0.025
cellular ketone metabolic process GO:0042180 51 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
mesenchymal cell proliferation GO:0010463 4 0.024
cellular response to peptide hormone stimulus GO:0071375 120 0.024
Rat
negative regulation of innate immune response GO:0045824 4 0.024
cell differentiation involved in kidney development GO:0061005 4 0.023
negative regulation of epithelial cell differentiation GO:0030857 5 0.023
ribose phosphate biosynthetic process GO:0046390 87 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.022
positive regulation of nucleotide metabolic process GO:0045981 91 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
skeletal muscle satellite cell proliferation GO:0014841 1 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
cell differentiation involved in metanephros development GO:0072202 1 0.021
rna metabolic process GO:0016070 406 0.021
Human Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.021
Human Rat
response to extracellular stimulus GO:0009991 380 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
regulation of erythrocyte aggregation GO:0034118 1 0.020
cellular response to nutrient levels GO:0031669 60 0.020
organ regeneration GO:0031100 101 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.019
metanephric tubule development GO:0072170 4 0.019
maternal process involved in female pregnancy GO:0060135 38 0.019
response to interferon beta GO:0035456 1 0.018
mitochondrion organization GO:0007005 35 0.018
oxoacid metabolic process GO:0043436 290 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
metal ion homeostasis GO:0055065 186 0.018
regulation of protein modification process GO:0031399 194 0.018
Rat
regulation of camp metabolic process GO:0030814 43 0.017
regulation of ossification GO:0030278 32 0.017
regeneration GO:0031099 163 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
ion homeostasis GO:0050801 212 0.017
negative regulation of metabolic process GO:0009892 331 0.017
Rat
cellular amine metabolic process GO:0044106 38 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
Human Rat
negative regulation of hydrogen peroxide biosynthetic process GO:0010730 2 0.017
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 8 0.017
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 1 0.017
kidney mesenchymal cell proliferation GO:0072135 1 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
negative regulation of cell death GO:0060548 229 0.017
glucose homeostasis GO:0042593 75 0.017
ribonucleoside monophosphate metabolic process GO:0009161 88 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
multi multicellular organism process GO:0044706 138 0.016
Rat
negative regulation of jak stat cascade GO:0046426 3 0.016
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
regulation of p38mapk cascade GO:1900744 1 0.016
cellular response to starvation GO:0009267 27 0.015
negative regulation of cell development GO:0010721 82 0.015
jak stat cascade GO:0007259 26 0.015
Rat
regulation of rna biosynthetic process GO:2001141 381 0.015
Human Rat
nucleoside metabolic process GO:0009116 179 0.015
regulation of cell differentiation GO:0045595 320 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
regulation of skeletal muscle cell proliferation GO:0014857 2 0.015
regulation of cell development GO:0060284 263 0.015
single organism intracellular transport GO:1902582 166 0.015
aging GO:0007568 241 0.015
cellular response to stress GO:0033554 269 0.014
blood circulation GO:0008015 183 0.014
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.014
microtubule organizing center organization GO:0031023 1 0.014
positive regulation of atp biosynthetic process GO:2001171 2 0.014
kidney mesenchyme development GO:0072074 2 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
renal vesicle development GO:0072087 4 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
response to interleukin 1 GO:0070555 55 0.014
Rat
regulation of nephron tubule epithelial cell differentiation GO:0072182 1 0.014
deoxyribonucleoside diphosphate metabolic process GO:0009186 4 0.014
secretion GO:0046903 307 0.014
rhythmic process GO:0048511 156 0.014
purine ribonucleoside biosynthetic process GO:0046129 21 0.013
neuron development GO:0048666 286 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
cellular response to peptide GO:1901653 133 0.013
Rat
regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 1 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
mitotic spindle organization GO:0007052 2 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
positive regulation of gene expression GO:0010628 244 0.013
Human Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.013
response to purine containing compound GO:0014074 126 0.013
macromolecular complex assembly GO:0065003 273 0.012
acute phase response GO:0006953 20 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
response to nutrient GO:0007584 248 0.012
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
negative regulation of signaling GO:0023057 157 0.012
Rat
membrane organization GO:0061024 94 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
Human Rat
negative regulation of leukocyte mediated immunity GO:0002704 6 0.012
multicellular organismal response to stress GO:0033555 25 0.012
muscle tissue development GO:0060537 58 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
secretion by tissue GO:0032941 37 0.011
positive regulation of camp mediated signaling GO:0043950 2 0.011
antigen processing and presentation of peptide antigen GO:0048002 2 0.011
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.011
Rat
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
regulation of protein export from nucleus GO:0046825 4 0.011
protein complex biogenesis GO:0070271 263 0.011
metanephric epithelium development GO:0072207 4 0.011
response to carbohydrate GO:0009743 183 0.011
negative regulation of reactive oxygen species metabolic process GO:2000378 7 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
Human Rat
protein complex assembly GO:0006461 263 0.011
metanephric mesenchyme development GO:0072075 2 0.010
smooth muscle cell proliferation GO:0048659 77 0.010
response to monosaccharide GO:0034284 159 0.010
cellular component assembly GO:0022607 360 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
Rat
t cell mediated immunity GO:0002456 7 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
neuron differentiation GO:0030182 368 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
Rat
acute inflammatory response GO:0002526 58 0.010

Irf7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nephritis DOID:10952 0 0.069
glomerulonephritis DOID:2921 0 0.069
focal segmental glomerulosclerosis DOID:1312 0 0.069
kidney disease DOID:557 0 0.069
disease of anatomical entity DOID:7 0 0.069
urinary system disease DOID:18 0 0.069
glomerulosclerosis DOID:0050851 0 0.069
diabetes mellitus DOID:9351 0 0.039
disease of metabolism DOID:0014667 0 0.039
carbohydrate metabolism disease DOID:0050013 0 0.039
type 1 diabetes mellitus DOID:9744 0 0.039
glucose metabolism disease DOID:4194 0 0.039
acquired metabolic disease DOID:0060158 0 0.039