Rattus norvegicus

185 known processes

Isl1

ISL LIM homeobox 1

(Aliases: isl-1=homeobox,Isl-1)

Isl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transport GO:0051050 245 0.408
cell morphogenesis involved in differentiation GO:0000904 119 0.309
Zebrafish Mouse Fly
regulation of transcription dna templated GO:0006355 374 0.274
regulation of rna metabolic process GO:0051252 391 0.268
regulation of multicellular organismal development GO:2000026 376 0.239
Mouse
neuron development GO:0048666 286 0.225
regulation of molecular function GO:0065009 398 0.219
intracellular transport GO:0046907 185 0.216
cell projection morphogenesis GO:0048858 123 0.214
Zebrafish Mouse Fly
regulation of system process GO:0044057 208 0.209
Zebrafish
neuron projection morphogenesis GO:0048812 122 0.205
Zebrafish Mouse Fly
neuropeptide signaling pathway GO:0007218 29 0.198
head development GO:0060322 247 0.197
Mouse Worm
nucleic acid templated transcription GO:0097659 379 0.189
regulation of catalytic activity GO:0050790 304 0.185
cation transmembrane transport GO:0098655 263 0.183
regulation of metal ion transport GO:0010959 118 0.154
protein transport GO:0015031 132 0.152
transcription from rna polymerase ii promoter GO:0006366 252 0.148
rna metabolic process GO:0016070 406 0.145
regulation of neuron differentiation GO:0045664 208 0.145
Mouse
negative regulation of macromolecule metabolic process GO:0010605 260 0.144
Mouse
calcium ion transport GO:0006816 131 0.139
regulation of neurogenesis GO:0050767 247 0.135
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.134
response to glucocorticoid GO:0051384 223 0.131
transmembrane transport GO:0055085 412 0.129
growth GO:0040007 165 0.128
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.121
Zebrafish Mouse Fly
central nervous system development GO:0007417 311 0.121
Zebrafish Mouse
neuron differentiation GO:0030182 368 0.120
regulation of cell proliferation GO:0042127 359 0.119
Mouse
cell morphogenesis GO:0000902 142 0.117
Zebrafish Mouse Fly
amine metabolic process GO:0009308 38 0.117
regulation of nucleic acid templated transcription GO:1903506 380 0.113
cellular component morphogenesis GO:0032989 155 0.111
Zebrafish Mouse Fly
metal ion transport GO:0030001 289 0.109
positive regulation of developmental process GO:0051094 283 0.105
Mouse
cell part morphogenesis GO:0032990 123 0.102
Zebrafish Mouse Fly
cellular component assembly GO:0022607 360 0.102
cellular response to lipid GO:0071396 201 0.097
anatomical structure morphogenesis GO:0009653 298 0.092
Human Zebrafish Mouse Rat Worm Fly
cellular metal ion homeostasis GO:0006875 172 0.091
regulation of cell development GO:0060284 263 0.091
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.090
neurological system process GO:0050877 219 0.088
cellular protein localization GO:0034613 122 0.088
negative regulation of cellular metabolic process GO:0031324 281 0.088
Mouse
regulation of cellular component organization GO:0051128 368 0.087
transcription dna templated GO:0006351 377 0.087
positive regulation of multicellular organismal process GO:0051240 387 0.087
Mouse
macromolecular complex subunit organization GO:0043933 339 0.085
brain development GO:0007420 247 0.084
Mouse
embryonic skeletal system development GO:0048706 3 0.084
regulation of cellular localization GO:0060341 263 0.082
regulation of secretion GO:0051046 224 0.081
homeostatic process GO:0042592 331 0.080
Fly
single organism carbohydrate metabolic process GO:0044723 118 0.079
regulation of ion transport GO:0043269 245 0.079
muscle system process GO:0003012 115 0.079
single organism behavior GO:0044708 130 0.079
cellular chemical homeostasis GO:0055082 247 0.078
anion transport GO:0006820 178 0.077
cell projection organization GO:0030030 302 0.077
positive regulation of cellular biosynthetic process GO:0031328 295 0.077
response to ketone GO:1901654 182 0.077
regulation of axonogenesis GO:0050770 37 0.074
cellular ion homeostasis GO:0006873 184 0.074
response to metal ion GO:0010038 253 0.071
response to ethanol GO:0045471 162 0.070
behavior GO:0007610 205 0.068
neuron projection development GO:0031175 273 0.068
regulation of neuron projection development GO:0010975 161 0.067
regulation of protein metabolic process GO:0051246 289 0.066
Mouse
ion transmembrane transport GO:0034220 365 0.066
negative regulation of multicellular organismal process GO:0051241 203 0.065
Mouse
carbohydrate derivative metabolic process GO:1901135 346 0.065
embryonic skeletal system morphogenesis GO:0048704 3 0.064
cell cell signaling GO:0007267 335 0.063
positive regulation of cell communication GO:0010647 271 0.063
developmental growth GO:0048589 100 0.061
Zebrafish
regulation of peptide transport GO:0090087 87 0.060
response to wounding GO:0009611 254 0.058
calcium ion import GO:0070509 22 0.057
anterior posterior pattern specification GO:0009952 1 0.056
Fly
cation transport GO:0006812 382 0.056
regulation of nervous system development GO:0051960 264 0.056
Mouse
cellular component biogenesis GO:0044085 368 0.056
inorganic cation transmembrane transport GO:0098662 202 0.054
positive regulation of signaling GO:0023056 270 0.053
regulation of rna biosynthetic process GO:2001141 381 0.053
synaptic growth at neuromuscular junction GO:0051124 1 0.053
single organism intracellular transport GO:1902582 166 0.052
reproduction GO:0000003 245 0.052
multicellular organismal reproductive process GO:0048609 233 0.051
negative regulation of metabolic process GO:0009892 331 0.051
Mouse
positive regulation of molecular function GO:0044093 230 0.051
Mouse
metal ion homeostasis GO:0055065 186 0.050
circadian rhythm GO:0007623 88 0.050
positive regulation of long term synaptic potentiation GO:1900273 4 0.049
positive regulation of synaptic transmission GO:0050806 62 0.049
positive regulation of rna biosynthetic process GO:1902680 197 0.049
negative regulation of cellular biosynthetic process GO:0031327 161 0.048
Mouse
cellular catabolic process GO:0044248 295 0.048
regulation of signal transduction GO:0009966 318 0.048
negative regulation of gene expression GO:0010629 199 0.048
Mouse
positive regulation of ion transport GO:0043270 94 0.047
inorganic ion transmembrane transport GO:0098660 229 0.047
cognition GO:0050890 92 0.046
chemical homeostasis GO:0048878 292 0.046
single organism catabolic process GO:0044712 283 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
negative regulation of molecular function GO:0044092 133 0.045
cellular response to organonitrogen compound GO:0071417 197 0.044
camp biosynthetic process GO:0006171 47 0.044
positive regulation of neuron projection development GO:0010976 99 0.044
response to growth factor GO:0070848 189 0.043
Rat
synaptic transmission GO:0007268 235 0.042
organonitrogen compound catabolic process GO:1901565 179 0.042
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.042
Mouse
aging GO:0007568 241 0.041
positive regulation of response to stimulus GO:0048584 285 0.041
Mouse
glycosyl compound catabolic process GO:1901658 126 0.041
regulation of cell projection organization GO:0031344 175 0.041
response to extracellular stimulus GO:0009991 380 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.041
Mouse
response to nutrient levels GO:0031667 370 0.041
regulation of transmembrane transport GO:0034762 122 0.040
protein complex subunit organization GO:0071822 302 0.040
axon development GO:0061564 96 0.040
rhythmic process GO:0048511 156 0.040
axonogenesis GO:0007409 71 0.040
Zebrafish Mouse Fly
negative regulation of neurogenesis GO:0050768 78 0.040
Mouse
transmission of nerve impulse GO:0019226 42 0.039
positive regulation of biosynthetic process GO:0009891 319 0.039
intracellular protein transport GO:0006886 79 0.039
immune system process GO:0002376 204 0.039
Fly
organelle organization GO:0006996 266 0.039
g protein coupled receptor signaling pathway GO:0007186 242 0.039
rna biosynthetic process GO:0032774 380 0.039
positive regulation of transcription dna templated GO:0045893 197 0.038
response to radiation GO:0009314 137 0.038
response to purine containing compound GO:0014074 126 0.038
nucleoside phosphate catabolic process GO:1901292 140 0.038
sensory perception GO:0007600 101 0.038
divalent metal ion transport GO:0070838 132 0.037
negative regulation of phosphate metabolic process GO:0045936 80 0.037
cellular homeostasis GO:0019725 252 0.037
response to inorganic substance GO:0010035 377 0.036
positive regulation of intracellular signal transduction GO:1902533 138 0.036
Mouse
cellular nitrogen compound catabolic process GO:0044270 163 0.036
reproductive process GO:0022414 372 0.036
Worm
cellular amine metabolic process GO:0044106 38 0.035
forebrain development GO:0030900 98 0.035
Mouse
peptide secretion GO:0002790 86 0.034
negative regulation of ion transport GO:0043271 51 0.034
purine nucleotide metabolic process GO:0006163 229 0.033
neuron projection guidance GO:0097485 24 0.033
Mouse Fly
developmental growth involved in morphogenesis GO:0060560 33 0.033
Zebrafish
negative regulation of transcription dna templated GO:0045892 116 0.033
Mouse
regulation of blood circulation GO:1903522 110 0.033
Zebrafish
behavioral response to ethanol GO:0048149 1 0.033
cellular response to oxygen containing compound GO:1901701 386 0.033
protein complex assembly GO:0006461 263 0.033
regulation of purine nucleotide catabolic process GO:0033121 65 0.033
cellular amino acid metabolic process GO:0006520 107 0.032
actin filament based process GO:0030029 86 0.032
muscle structure development GO:0061061 87 0.032
Zebrafish Mouse Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.032
multicellular organism reproduction GO:0032504 233 0.032
single organism biosynthetic process GO:0044711 342 0.032
single organism organelle organization GO:1902589 180 0.032
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.032
regulation of muscle system process GO:0090257 79 0.032
heart contraction GO:0060047 57 0.031
Zebrafish
regulation of hydrolase activity GO:0051336 143 0.031
organic cyclic compound catabolic process GO:1901361 175 0.031
heterocycle catabolic process GO:0046700 167 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
antral ovarian follicle growth GO:0001547 3 0.029
response to hexose GO:0009746 144 0.029
regulation of nucleoside metabolic process GO:0009118 66 0.029
divalent inorganic cation transport GO:0072511 134 0.029
single organism cellular localization GO:1902580 102 0.029
secretion GO:0046903 307 0.029
glucose homeostasis GO:0042593 75 0.029
cytoskeleton organization GO:0007010 111 0.029
regulation of heart contraction GO:0008016 48 0.029
Zebrafish
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.028
glycosyl compound metabolic process GO:1901657 182 0.028
regulation of body fluid levels GO:0050878 90 0.028
b cell differentiation GO:0030183 2 0.028
positive regulation of cell proliferation GO:0008284 249 0.028
Mouse
response to temperature stimulus GO:0009266 94 0.028
catabolic process GO:0009056 351 0.028
signal release GO:0023061 145 0.028
regulation of cell differentiation GO:0045595 320 0.028
Mouse
organophosphate metabolic process GO:0019637 370 0.027
ribonucleotide catabolic process GO:0009261 136 0.027
carbohydrate homeostasis GO:0033500 75 0.027
regulation of transferase activity GO:0051338 123 0.027
nucleotide catabolic process GO:0009166 139 0.027
cation homeostasis GO:0055080 195 0.026
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.026
protein localization GO:0008104 191 0.026
regulation of calcium ion transport GO:0051924 77 0.025
nucleoside triphosphate metabolic process GO:0009141 144 0.025
negative regulation of luteinizing hormone secretion GO:0033685 4 0.025
cellular cation homeostasis GO:0030003 180 0.025
purine ribonucleoside catabolic process GO:0046130 124 0.025
negative regulation of cell development GO:0010721 82 0.025
Mouse
organic substance catabolic process GO:1901575 316 0.025
macromolecular complex assembly GO:0065003 273 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
detection of temperature stimulus GO:0016048 4 0.024
organonitrogen compound biosynthetic process GO:1901566 167 0.024
embryonic cranial skeleton morphogenesis GO:0048701 2 0.024
synaptic transmission cholinergic GO:0007271 11 0.024
ion homeostasis GO:0050801 212 0.024
single organism reproductive process GO:0044702 297 0.024
Worm
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
positive regulation of secretion GO:0051047 140 0.024
ensheathment of neurons GO:0007272 40 0.024
regulation of ion transmembrane transport GO:0034765 121 0.024
potassium ion transport GO:0006813 97 0.024
protein complex biogenesis GO:0070271 263 0.023
negative regulation of cell differentiation GO:0045596 99 0.023
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
actin cytoskeleton organization GO:0030036 73 0.023
response to decreased oxygen levels GO:0036293 237 0.023
calcium ion homeostasis GO:0055074 162 0.023
erk1 and erk2 cascade GO:0070371 48 0.023
cellular response to glucocorticoid stimulus GO:0071385 68 0.023
carbohydrate derivative catabolic process GO:1901136 147 0.023
cytoplasmic transport GO:0016482 115 0.023
regulation of secretion by cell GO:1903530 208 0.023
multi organism reproductive process GO:0044703 262 0.023
response to corticosteroid GO:0031960 235 0.023
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.023
positive regulation of humoral immune response GO:0002922 2 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
regulation of cellular component biogenesis GO:0044087 86 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
maintenance of location GO:0051235 17 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
Mouse
cellular macromolecule localization GO:0070727 122 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
Mouse
hormone mediated signaling pathway GO:0009755 23 0.022
nucleotide metabolic process GO:0009117 279 0.022
ribonucleoside triphosphate catabolic process GO:0009203 122 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.021
enzyme linked receptor protein signaling pathway GO:0007167 116 0.021
Fly
negative regulation of protein phosphorylation GO:0001933 44 0.021
protein phosphorylation GO:0006468 345 0.021
Mouse
peptide hormone secretion GO:0030072 84 0.021
regulation of hormone secretion GO:0046883 106 0.021
nucleoside triphosphate catabolic process GO:0009143 123 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
Mouse
positive regulation of rna metabolic process GO:0051254 203 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.020
nitrogen compound transport GO:0071705 229 0.020
vesicle mediated transport GO:0016192 181 0.020
positive regulation of nervous system development GO:0051962 178 0.020
negative regulation of neuron differentiation GO:0045665 62 0.020
Mouse
response to testosterone GO:0033574 55 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.020
neuronal action potential GO:0019228 35 0.020
positive regulation of cell development GO:0010720 176 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
synaptic vesicle transport GO:0048489 23 0.020
cell cycle GO:0007049 101 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.019
carbohydrate metabolic process GO:0005975 130 0.019
learning or memory GO:0007611 90 0.019
leukocyte activation GO:0045321 76 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
telencephalon development GO:0021537 62 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
excretion GO:0007588 24 0.019
Worm
regulation of cell morphogenesis GO:0022604 77 0.019
nucleoside catabolic process GO:0009164 126 0.018
regulation of lyase activity GO:0051339 22 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
purine nucleotide catabolic process GO:0006195 136 0.018
jak stat cascade GO:0007259 26 0.018
Mouse
guanosine containing compound metabolic process GO:1901068 74 0.018
insulin secretion GO:0030073 69 0.018
sodium ion transmembrane transport GO:0035725 67 0.018
regulation of kinase activity GO:0043549 117 0.018
cellular response to acid chemical GO:0071229 75 0.018
protein processing GO:0016485 68 0.018
nucleoside metabolic process GO:0009116 179 0.018
lipid biosynthetic process GO:0008610 128 0.018
regulation of apoptotic process GO:0042981 335 0.018
Mouse
regulation of synaptic transmission glutamatergic GO:0051966 26 0.018
regulation of cellular catabolic process GO:0031329 101 0.018
organophosphate catabolic process GO:0046434 148 0.018
cell communication involved in cardiac conduction GO:0086065 2 0.017
regulation of defecation GO:2000292 1 0.017
acid secretion GO:0046717 48 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.017
positive regulation of hormone secretion GO:0046887 65 0.017
aromatic compound catabolic process GO:0019439 168 0.017
amine transport GO:0015837 57 0.017
muscle cell differentiation GO:0042692 52 0.017
Zebrafish Mouse Fly
nucleobase containing compound catabolic process GO:0034655 152 0.017
endocrine system development GO:0035270 30 0.017
Zebrafish Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.017
cyclic purine nucleotide metabolic process GO:0052652 62 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
cellular response to retinoic acid GO:0071300 27 0.017
calcium ion transmembrane transport GO:0070588 70 0.017
protein targeting GO:0006605 61 0.017
regulation of ion homeostasis GO:2000021 63 0.017
long term synaptic potentiation GO:0060291 21 0.016
detection of visible light GO:0009584 3 0.016
purine containing compound catabolic process GO:0072523 138 0.016
cellular response to corticosteroid stimulus GO:0071384 69 0.016
axon guidance GO:0007411 24 0.016
Mouse Fly
positive regulation of blood circulation GO:1903524 65 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
male mating behavior GO:0060179 3 0.016
myelination GO:0042552 39 0.016
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
locomotory exploration behavior GO:0035641 1 0.016
regulation of blood pressure GO:0008217 83 0.016
synapse assembly GO:0007416 29 0.016
monosaccharide metabolic process GO:0005996 61 0.016
heart development GO:0007507 72 0.016
Human Zebrafish Mouse Fly
negative regulation of catalytic activity GO:0043086 103 0.016
response to cocaine GO:0042220 39 0.016
regulation of developmental growth GO:0048638 45 0.016
negative regulation of purine nucleotide metabolic process GO:1900543 23 0.016
negative regulation of signaling GO:0023057 157 0.016
liver development GO:0001889 90 0.016
negative regulation of circadian rhythm GO:0042754 5 0.015
defense response GO:0006952 194 0.015
Mouse
positive regulation of cell death GO:0010942 184 0.015
response to peptide GO:1901652 292 0.015
intracellular signal transduction GO:0035556 314 0.015
Mouse
axis specification GO:0009798 4 0.015
Fly
synapse organization GO:0050808 46 0.015
cell type specific apoptotic process GO:0097285 134 0.015
Mouse
purine containing compound biosynthetic process GO:0072522 85 0.015
cell cycle checkpoint GO:0000075 2 0.015
response to peptide hormone GO:0043434 278 0.015
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
positive regulation of peptide secretion GO:0002793 52 0.015
regulation of catecholamine secretion GO:0050433 32 0.015
secretion by cell GO:0032940 248 0.015
response to food GO:0032094 27 0.015
diencephalon development GO:0021536 21 0.015
Mouse
renal system process GO:0003014 40 0.015
regulation of membrane potential GO:0042391 110 0.015
multicellular organismal signaling GO:0035637 44 0.014
response to hypoxia GO:0001666 231 0.014
regulation of cell cycle GO:0051726 73 0.014
proteolysis GO:0006508 175 0.014
positive regulation of serotonin secretion GO:0014064 1 0.014
behavioral response to cocaine GO:0048148 6 0.014
neurotrophin production GO:0032898 2 0.014
macromolecule localization GO:0033036 252 0.014
muscle contraction GO:0006936 88 0.014
nucleocytoplasmic transport GO:0006913 48 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
Mouse
regulation of cyclase activity GO:0031279 21 0.014
prepulse inhibition GO:0060134 1 0.014
wound healing GO:0042060 122 0.014
locomotion GO:0040011 237 0.014
Mouse Worm Fly
circadian regulation of gene expression GO:0032922 3 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
negative regulation of defecation GO:2000293 1 0.013
sensory perception of pain GO:0019233 73 0.013
dna metabolic process GO:0006259 96 0.013
camp metabolic process GO:0046058 63 0.013
multi multicellular organism process GO:0044706 138 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
response to glucose GO:0009749 136 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
establishment of protein localization GO:0045184 141 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
response to camp GO:0051591 91 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
regulation of hormone levels GO:0010817 187 0.013
regulation of nucleotide catabolic process GO:0030811 65 0.013
epithelium development GO:0060429 96 0.013
Zebrafish Rat Fly
negative regulation of calcium ion import GO:0090281 2 0.013
positive regulation of mast cell activation GO:0033005 4 0.013
negative regulation of epithelial cell proliferation GO:0050680 16 0.013
amide transport GO:0042886 105 0.013
regulation of protein localization GO:0032880 81 0.013
circulatory system process GO:0003013 183 0.013
Zebrafish
single organism carbohydrate catabolic process GO:0044724 40 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
organic hydroxy compound transport GO:0015850 77 0.013
response to oxygen levels GO:0070482 265 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
positive regulation of nucleotide catabolic process GO:0030813 53 0.013
dicarboxylic acid transport GO:0006835 34 0.013
adult locomotory behavior GO:0008344 4 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
regeneration GO:0031099 163 0.012
heart process GO:0003015 57 0.012
Zebrafish
cellular ketone metabolic process GO:0042180 51 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
action potential GO:0001508 54 0.012
hexose metabolic process GO:0019318 58 0.012
chemosensory behavior GO:0007635 2 0.012
regulation of growth GO:0040008 105 0.012
glucose metabolic process GO:0006006 52 0.012
response to retinoic acid GO:0032526 63 0.012
oxoacid metabolic process GO:0043436 290 0.012
regulation of adenylate cyclase activity GO:0045761 18 0.012
cell growth GO:0016049 104 0.012
Zebrafish
olfactory behavior GO:0042048 2 0.012
norepinephrine secretion GO:0048243 16 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
regulation of amine transport GO:0051952 54 0.012
exploration behavior GO:0035640 1 0.012
response to cytokine GO:0034097 215 0.012
regulation of homeostatic process GO:0032844 101 0.012
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.011
programmed cell death GO:0012501 392 0.011
Mouse
sensory perception of light stimulus GO:0050953 3 0.011
protein autophosphorylation GO:0046777 66 0.011
detection of temperature stimulus involved in sensory perception of pain GO:0050965 4 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
Mouse
positive regulation of cell projection organization GO:0031346 111 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
Mouse
organic acid metabolic process GO:0006082 292 0.011
regulation of insulin secretion GO:0050796 65 0.011
cellular component movement GO:0006928 248 0.011
Mouse Fly
multicellular organism growth GO:0035264 1 0.011
purine containing compound metabolic process GO:0072521 253 0.011
gtp catabolic process GO:0006184 71 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.011
Mouse
gastric motility GO:0035482 3 0.011
membrane repolarization GO:0086009 1 0.011
regulation of norepinephrine secretion GO:0014061 15 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
asymmetric stem cell division GO:0098722 2 0.011
lipid storage GO:0019915 1 0.011
regulation of synaptic transmission GO:0050804 141 0.011
regulation of intracellular transport GO:0032386 65 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
negative regulation of calcium ion transport GO:0051926 14 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
Mouse
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of erk1 and erk2 cascade GO:0070372 41 0.011
hormone secretion GO:0046879 115 0.011
positive regulation of synaptic transmission glutamatergic GO:0051968 13 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
protein heterooligomerization GO:0051291 89 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
negative regulation of protein metabolic process GO:0051248 114 0.010
positive regulation of adenylate cyclase activity GO:0045762 12 0.010
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 2 0.010
regulation of cell cycle process GO:0010564 31 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
Mouse
negative regulation of transport GO:0051051 136 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
regulation of organelle organization GO:0033043 80 0.010
response to starvation GO:0042594 59 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
positive regulation of developmental growth GO:0048639 29 0.010
memory GO:0007613 54 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010

Isl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.021
nervous system disease DOID:863 0 0.018
disease of anatomical entity DOID:7 0 0.018
inherited metabolic disorder DOID:655 0 0.014
urinary system disease DOID:18 0 0.011
hypothyroidism DOID:1459 0 0.011
thyroid gland disease DOID:50 0 0.011
endocrine system disease DOID:28 0 0.011
congenital hypothyroidism DOID:0050328 0 0.011