Rattus norvegicus

0 known processes

Isl2

ISL LIM homeobox 2

Isl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecular complex subunit organization GO:0043933 339 0.174
rhythmic process GO:0048511 156 0.174
neurological system process GO:0050877 219 0.171
protein complex subunit organization GO:0071822 302 0.157
protein complex biogenesis GO:0070271 263 0.126
metal ion transport GO:0030001 289 0.125
cation transport GO:0006812 382 0.118
response to extracellular stimulus GO:0009991 380 0.114
cell cell signaling GO:0007267 335 0.112
Rat
cellular component assembly GO:0022607 360 0.108
forebrain development GO:0030900 98 0.106
phasic smooth muscle contraction GO:0014821 3 0.105
nitrogen compound transport GO:0071705 229 0.105
Rat
macromolecular complex assembly GO:0065003 273 0.103
cellular component biogenesis GO:0044085 368 0.101
telencephalon development GO:0021537 62 0.095
response to ethanol GO:0045471 162 0.095
protein oligomerization GO:0051259 191 0.086
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.085
positive regulation of biosynthetic process GO:0009891 319 0.085
Rat Fly
reproductive process GO:0022414 372 0.083
Worm
cell cycle GO:0007049 101 0.081
rna biosynthetic process GO:0032774 380 0.080
Rat Fly
anion transport GO:0006820 178 0.078
regulation of ion transport GO:0043269 245 0.077
protein complex assembly GO:0006461 263 0.076
single organism behavior GO:0044708 130 0.075
intracellular signal transduction GO:0035556 314 0.070
regulation of cell proliferation GO:0042127 359 0.070
cellular protein localization GO:0034613 122 0.068
secretion GO:0046903 307 0.068
Rat
tissue development GO:0009888 252 0.067
Rat Fly
programmed cell death GO:0012501 392 0.064
negative regulation of cellular biosynthetic process GO:0031327 161 0.064
learning or memory GO:0007611 90 0.064
multicellular organism reproduction GO:0032504 233 0.063
positive regulation of multicellular organismal process GO:0051240 387 0.062
protein phosphorylation GO:0006468 345 0.062
sensory perception GO:0007600 101 0.061
potassium ion transport GO:0006813 97 0.060
regulation of system process GO:0044057 208 0.060
regulation of secretion GO:0051046 224 0.059
Rat
behavior GO:0007610 205 0.058
positive regulation of phosphate metabolic process GO:0045937 262 0.057
regulation of cellular component organization GO:0051128 368 0.056
regulation of rna metabolic process GO:0051252 391 0.056
Rat Fly
regulation of rna biosynthetic process GO:2001141 381 0.055
Rat Fly
regulation of membrane potential GO:0042391 110 0.054
urinary bladder smooth muscle contraction GO:0014832 4 0.053
regulation of body fluid levels GO:0050878 90 0.053
n methyl d aspartate receptor clustering GO:0097114 2 0.052
cellular macromolecule localization GO:0070727 122 0.052
heart development GO:0007507 72 0.052
Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.051
response to estradiol GO:0032355 164 0.051
regulation of cell development GO:0060284 263 0.050
Mouse
tonic smooth muscle contraction GO:0014820 4 0.050
regulation of transcription dna templated GO:0006355 374 0.050
Rat Fly
vascular process in circulatory system GO:0003018 96 0.050
positive regulation of cell development GO:0010720 176 0.050
carboxylic acid transport GO:0046942 115 0.049
anterior posterior pattern specification GO:0009952 1 0.048
Fly
synaptic transmission GO:0007268 235 0.048
transmembrane transport GO:0055085 412 0.048
positive regulation of cell proliferation GO:0008284 249 0.048
organic anion transport GO:0015711 132 0.046
regulation of behavior GO:0050795 61 0.045
rna metabolic process GO:0016070 406 0.045
Rat Fly
neuron development GO:0048666 286 0.045
Zebrafish Mouse Rat Fly
macromolecule localization GO:0033036 252 0.045
secretion by cell GO:0032940 248 0.044
Rat
locomotion GO:0040011 237 0.043
Zebrafish Mouse Worm Fly
neuron projection development GO:0031175 273 0.043
Zebrafish Mouse Rat Fly
purine nucleoside metabolic process GO:0042278 169 0.043
purine nucleotide metabolic process GO:0006163 229 0.042
purine nucleoside triphosphate catabolic process GO:0009146 122 0.042
oxoacid metabolic process GO:0043436 290 0.041
carbohydrate derivative metabolic process GO:1901135 346 0.041
negative regulation of biosynthetic process GO:0009890 168 0.041
synapse organization GO:0050808 46 0.040
circadian rhythm GO:0007623 88 0.040
response to food GO:0032094 27 0.040
enzyme linked receptor protein signaling pathway GO:0007167 116 0.040
Fly
urinary tract smooth muscle contraction GO:0014848 4 0.039
cellular amino acid metabolic process GO:0006520 107 0.039
purine ribonucleotide catabolic process GO:0009154 136 0.038
negative regulation of developmental process GO:0051093 125 0.038
Mouse
organophosphate metabolic process GO:0019637 370 0.038
negative regulation of cell differentiation GO:0045596 99 0.038
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
Rat Fly
central nervous system development GO:0007417 311 0.038
Mouse
apoptotic process GO:0006915 381 0.037
multicellular organismal reproductive process GO:0048609 233 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
Rat Fly
cellular ketone metabolic process GO:0042180 51 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.036
small gtpase mediated signal transduction GO:0007264 36 0.036
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
positive regulation of cellular component organization GO:0051130 200 0.035
protein heterooligomerization GO:0051291 89 0.035
purine ribonucleoside catabolic process GO:0046130 124 0.034
transcription dna templated GO:0006351 377 0.034
Rat Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.034
regulation of multicellular organismal development GO:2000026 376 0.034
Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.034
ribonucleoside triphosphate catabolic process GO:0009203 122 0.034
g protein coupled receptor signaling pathway GO:0007186 242 0.033
response to nutrient GO:0007584 248 0.033
positive regulation of gene expression GO:0010628 244 0.033
Rat Fly
cardiovascular system development GO:0072358 134 0.033
Fly
regulation of developmental growth GO:0048638 45 0.033
organophosphate catabolic process GO:0046434 148 0.033
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.033
reproduction GO:0000003 245 0.032
brain development GO:0007420 247 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
regulation of cellular component movement GO:0051270 150 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.031
Rat Fly
neuron fate commitment GO:0048663 4 0.031
Zebrafish Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.031
glycosyl compound metabolic process GO:1901657 182 0.030
monocarboxylic acid transport GO:0015718 52 0.030
amine metabolic process GO:0009308 38 0.030
purine nucleotide catabolic process GO:0006195 136 0.030
aging GO:0007568 241 0.030
negative regulation of signaling GO:0023057 157 0.030
Rat
organic acid metabolic process GO:0006082 292 0.030
thyroid gland development GO:0030878 1 0.029
saliva secretion GO:0046541 3 0.029
purine ribonucleotide metabolic process GO:0009150 227 0.029
nucleic acid templated transcription GO:0097659 379 0.029
Rat Fly
ribonucleotide catabolic process GO:0009261 136 0.029
negative regulation of cell development GO:0010721 82 0.029
Mouse
organelle organization GO:0006996 266 0.029
diaphragm contraction GO:0002086 2 0.029
response to nutrient levels GO:0031667 370 0.028
circulatory system process GO:0003013 183 0.028
head development GO:0060322 247 0.028
Worm
neuromuscular synaptic transmission GO:0007274 2 0.028
regulation of transmembrane transporter activity GO:0022898 49 0.028
nucleotide metabolic process GO:0009117 279 0.028
regulation of programmed cell death GO:0043067 341 0.028
multi organism reproductive process GO:0044703 262 0.028
single organism catabolic process GO:0044712 283 0.028
response to nicotine GO:0035094 51 0.028
regulation of apoptotic process GO:0042981 335 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.027
Rat Fly
single organism organelle organization GO:1902589 180 0.027
regulation of cellular component biogenesis GO:0044087 86 0.027
regulation of cell growth GO:0001558 85 0.027
serotonin receptor signaling pathway GO:0007210 10 0.026
carbohydrate derivative catabolic process GO:1901136 147 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
peptidyl amino acid modification GO:0018193 126 0.026
response to ketone GO:1901654 182 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
cellular nitrogen compound catabolic process GO:0044270 163 0.026
response to wounding GO:0009611 254 0.026
Rat
organic substance catabolic process GO:1901575 316 0.026
purine containing compound catabolic process GO:0072523 138 0.026
response to estrogen GO:0043627 232 0.026
ribonucleoside triphosphate metabolic process GO:0009199 141 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
cell growth GO:0016049 104 0.025
Zebrafish
embryonic skeletal system development GO:0048706 3 0.025
positive regulation of developmental process GO:0051094 283 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.025
glycosyl compound catabolic process GO:1901658 126 0.025
regulation of tube size GO:0035150 89 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.024
Mouse
organonitrogen compound catabolic process GO:1901565 179 0.024
cation homeostasis GO:0055080 195 0.024
acid secretion GO:0046717 48 0.024
intracellular protein transport GO:0006886 79 0.024
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.024
positive regulation of long term synaptic potentiation GO:1900273 4 0.024
mapk cascade GO:0000165 140 0.023
regulation of synaptic transmission GO:0050804 141 0.023
cellular amine metabolic process GO:0044106 38 0.023
regulation of cell projection organization GO:0031344 175 0.023
cellular response to cytokine stimulus GO:0071345 127 0.023
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.023
regulation of ion transmembrane transport GO:0034765 121 0.023
cytoskeleton organization GO:0007010 111 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
cardiac chamber development GO:0003205 1 0.023
ribonucleoside catabolic process GO:0042454 126 0.023
cellular response to lipid GO:0071396 201 0.023
Rat
purine containing compound metabolic process GO:0072521 253 0.023
reproductive system development GO:0061458 128 0.023
Worm
negative regulation of neurogenesis GO:0050768 78 0.022
Mouse
heterocycle catabolic process GO:0046700 167 0.022
wound healing GO:0042060 122 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
Rat Fly
axonogenesis GO:0007409 71 0.022
Zebrafish Mouse Fly
ion transmembrane transport GO:0034220 365 0.022
purine ribonucleoside metabolic process GO:0046128 168 0.022
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.021
positive regulation of nervous system development GO:0051962 178 0.021
single organism reproductive process GO:0044702 297 0.021
Worm
sex differentiation GO:0007548 113 0.021
Worm
biological adhesion GO:0022610 110 0.021
response to lipopolysaccharide GO:0032496 191 0.021
nucleoside metabolic process GO:0009116 179 0.021
positive regulation of cell death GO:0010942 184 0.021
regulation of ion transmembrane transporter activity GO:0032412 48 0.021
neuron differentiation GO:0030182 368 0.021
Zebrafish Mouse Rat Fly
regulation of blood circulation GO:1903522 110 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
muscle system process GO:0003012 115 0.021
nucleoside catabolic process GO:0009164 126 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
regulation of neurogenesis GO:0050767 247 0.020
Mouse
response to vitamin GO:0033273 131 0.020
response to toxic substance GO:0009636 133 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
Rat Fly
cellular response to acid chemical GO:0071229 75 0.020
regulation of cellular localization GO:0060341 263 0.020
Rat
ossification GO:0001503 70 0.020
heart morphogenesis GO:0003007 3 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
nucleoside triphosphate metabolic process GO:0009141 144 0.020
cell projection organization GO:0030030 302 0.020
Zebrafish Mouse Rat Fly
nucleoside triphosphate catabolic process GO:0009143 123 0.020
response to acid chemical GO:0001101 222 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
Rat Fly
eye morphogenesis GO:0048592 4 0.020
positive regulation of sodium ion transport GO:0010765 10 0.020
regulation of blood vessel size GO:0050880 89 0.020
regulation of organelle organization GO:0033043 80 0.020
regulation of anatomical structure size GO:0090066 135 0.020
calcium ion transport GO:0006816 131 0.019
phospholipase c activating serotonin receptor signaling pathway GO:0007208 2 0.019
organic hydroxy compound transport GO:0015850 77 0.019
regulation of secretion by cell GO:1903530 208 0.019
Rat
positive regulation of cellular component biogenesis GO:0044089 55 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
Rat Fly
sexual reproduction GO:0019953 148 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
amine transport GO:0015837 57 0.019
response to cocaine GO:0042220 39 0.019
regulation of cell differentiation GO:0045595 320 0.019
Mouse
hippocampus development GO:0021766 30 0.019
negative regulation of metabolic process GO:0009892 331 0.019
homeostatic process GO:0042592 331 0.019
Fly
metal ion homeostasis GO:0055065 186 0.019
sensory organ development GO:0007423 74 0.018
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.018
lipid transport GO:0006869 61 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
development of primary sexual characteristics GO:0045137 107 0.018
Worm
protein localization GO:0008104 191 0.018
negative regulation of cell communication GO:0010648 158 0.018
Rat
response to growth factor GO:0070848 189 0.018
Rat
protein homooligomerization GO:0051260 91 0.018
muscle cell differentiation GO:0042692 52 0.018
Fly
response to transition metal nanoparticle GO:1990267 122 0.018
muscle contraction GO:0006936 88 0.018
regulation of muscle organ development GO:0048634 26 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
transmission of nerve impulse GO:0019226 42 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
cardiac ventricle development GO:0003231 1 0.018
regulation of muscle tissue development GO:1901861 25 0.018
ribose phosphate metabolic process GO:0019693 235 0.017
divalent metal ion transport GO:0070838 132 0.017
cell morphogenesis GO:0000902 142 0.017
Zebrafish Mouse Fly
muscle structure development GO:0061061 87 0.017
Fly
negative regulation of nervous system development GO:0051961 79 0.017
Mouse
epithelium development GO:0060429 96 0.017
Rat Fly
ras protein signal transduction GO:0007265 29 0.017
chemical homeostasis GO:0048878 292 0.017
cellular component movement GO:0006928 248 0.017
Zebrafish Mouse Fly
regulation of inhibitory postsynaptic membrane potential GO:0060080 6 0.017
renal system process GO:0003014 40 0.017
regulation of saliva secretion GO:0046877 3 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
regulation of nucleotide catabolic process GO:0030811 65 0.017
single organism cellular localization GO:1902580 102 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
regulation of cell cycle GO:0051726 73 0.017
growth GO:0040007 165 0.017
Zebrafish
response to external biotic stimulus GO:0043207 221 0.017
regulation of metal ion transport GO:0010959 118 0.016
muscle tissue development GO:0060537 58 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
positive regulation of saliva secretion GO:0046878 3 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
monoamine transport GO:0015844 43 0.016
regulation of hydrolase activity GO:0051336 143 0.016
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.016
membrane hyperpolarization GO:0060081 11 0.016
eye development GO:0001654 50 0.016
response to alkaloid GO:0043279 132 0.016
receptor clustering GO:0043113 13 0.016
regulation of neuron projection development GO:0010975 161 0.016
cognition GO:0050890 92 0.016
smooth muscle contraction GO:0006939 37 0.016
skeletal system development GO:0001501 41 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
positive regulation of digestive system process GO:0060456 8 0.015
response to camp GO:0051591 91 0.015
signal release GO:0023061 145 0.015
Rat
artery smooth muscle contraction GO:0014824 4 0.015
hormone secretion GO:0046879 115 0.015
Rat
positive regulation of programmed cell death GO:0043068 157 0.015
cellular cation homeostasis GO:0030003 180 0.015
regulation of neuron differentiation GO:0045664 208 0.015
Mouse
phospholipid metabolic process GO:0006644 61 0.015
one carbon compound transport GO:0019755 5 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
organic acid transport GO:0015849 116 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
embryonic cranial skeleton morphogenesis GO:0048701 2 0.015
muscle cell development GO:0055001 26 0.015
developmental growth GO:0048589 100 0.015
Zebrafish
camera type eye morphogenesis GO:0048593 2 0.015
regulation of systemic arterial blood pressure GO:0003073 30 0.015
regulation of amine transport GO:0051952 54 0.015
renal system development GO:0072001 67 0.015
Rat
regulation of sodium ion transport GO:0002028 21 0.015
response to radiation GO:0009314 137 0.015
localization of cell GO:0051674 202 0.015
synaptic transmission cholinergic GO:0007271 11 0.015
vasodilation GO:0042311 44 0.014
behavioral response to nicotine GO:0035095 2 0.014
cell migration GO:0016477 197 0.014
actin cytoskeleton organization GO:0030036 73 0.014
embryonic pattern specification GO:0009880 1 0.014
Fly
dopamine secretion GO:0014046 15 0.014
choline transport GO:0015871 4 0.014
response to biotic stimulus GO:0009607 226 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
divalent inorganic cation transport GO:0072511 134 0.014
regulation of cytoskeleton organization GO:0051493 49 0.014
lipid biosynthetic process GO:0008610 128 0.014
organ regeneration GO:0031100 101 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
regulation of skeletal muscle tissue growth GO:0048631 3 0.014
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.014
response to carbohydrate GO:0009743 183 0.014
regulation of appetite GO:0032098 8 0.014
autonomic nervous system development GO:0048483 3 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
regulation of synaptic transmission gabaergic GO:0032228 17 0.013
defense response GO:0006952 194 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
oxidation reduction process GO:0055114 304 0.013
positive regulation of signaling GO:0023056 270 0.013
Rat
regulation of response to stress GO:0080134 126 0.013
musculoskeletal movement GO:0050881 17 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
Rat Fly
ovulation cycle process GO:0022602 50 0.013
response to cytokine GO:0034097 215 0.013
respiratory system process GO:0003016 3 0.013
postsynaptic membrane organization GO:0001941 5 0.013
cellular lipid metabolic process GO:0044255 208 0.013
nucleoside monophosphate catabolic process GO:0009125 56 0.013
neuron neuron synaptic transmission GO:0007270 60 0.013
nucleocytoplasmic transport GO:0006913 48 0.013
axis specification GO:0009798 4 0.013
Fly
cell cycle process GO:0022402 57 0.013
positive regulation of cell communication GO:0010647 271 0.013
Rat
response to glucose GO:0009749 136 0.013
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 2 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
immune system process GO:0002376 204 0.012
Fly
copulation GO:0007620 17 0.012
regulation of protein kinase activity GO:0045859 105 0.012
regulation of blood pressure GO:0008217 83 0.012
regulation of ossification GO:0030278 32 0.012
regulation of growth GO:0040008 105 0.012
cytoplasmic transport GO:0016482 115 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
developmental process involved in reproduction GO:0003006 159 0.012
Worm
negative regulation of cell proliferation GO:0008285 119 0.012
lipid metabolic process GO:0006629 283 0.012
pallium development GO:0021543 42 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
positive regulation of renin secretion into blood stream GO:1900135 1 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
negative regulation of growth GO:0045926 37 0.012
regulation of phosphorylation GO:0042325 248 0.012
embryo development GO:0009790 49 0.012
Fly
detection of temperature stimulus involved in sensory perception of pain GO:0050965 4 0.012
vasoconstriction GO:0042310 54 0.012
glucan metabolic process GO:0044042 23 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
positive regulation of synaptic transmission GO:0050806 62 0.012
positive regulation of amine transport GO:0051954 26 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
positive regulation of nucleotide catabolic process GO:0030813 53 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
rho protein signal transduction GO:0007266 11 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
involuntary skeletal muscle contraction GO:0003011 2 0.012
nucleotide catabolic process GO:0009166 139 0.012
catabolic process GO:0009056 351 0.011
response to retinoic acid GO:0032526 63 0.011
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.011
regulation of homotypic cell cell adhesion GO:0034110 4 0.011
response to other organism GO:0051707 220 0.011
single organismal cell cell adhesion GO:0016337 42 0.011
spinal cord development GO:0021510 27 0.011
Mouse
response to dexamethasone GO:0071548 49 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
cell projection morphogenesis GO:0048858 123 0.011
Zebrafish Mouse Fly
chemosensory behavior GO:0007635 2 0.011
regulation of kinase activity GO:0043549 117 0.011
multi multicellular organism process GO:0044706 138 0.011
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.011
brain renin angiotensin system GO:0002035 3 0.011
cellular catabolic process GO:0044248 295 0.011
cell cycle checkpoint GO:0000075 2 0.011
positive regulation of ion transport GO:0043270 94 0.011
negative regulation of transport GO:0051051 136 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
cellular ion homeostasis GO:0006873 184 0.011
retinal ganglion cell axon guidance GO:0031290 1 0.011
Mouse
camera type eye development GO:0043010 48 0.011
intracellular transport GO:0046907 185 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
aromatic compound catabolic process GO:0019439 168 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
olfactory behavior GO:0042048 2 0.011
negative regulation of molecular function GO:0044092 133 0.011
Rat Fly
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
regulation of transporter activity GO:0032409 50 0.011
circulatory system development GO:0072359 134 0.011
Fly
negative regulation of gene expression GO:0010629 199 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
response to mechanical stimulus GO:0009612 134 0.011
regulation of neuronal synaptic plasticity GO:0048168 31 0.011
response to testosterone GO:0033574 55 0.010
blood circulation GO:0008015 183 0.010
regulation of molecular function GO:0065009 398 0.010
Rat Fly
regulation of signal transduction GO:0009966 318 0.010
Rat
sensory perception of mechanical stimulus GO:0050954 17 0.010
sympathetic nervous system development GO:0048485 1 0.010
response to hypoxia GO:0001666 231 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
detection of temperature stimulus GO:0016048 4 0.010
regulation of vasodilation GO:0042312 36 0.010
dendrite development GO:0016358 72 0.010
Fly
vesicle mediated transport GO:0016192 181 0.010
blood vessel development GO:0001568 69 0.010

Isl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.035
disease of anatomical entity DOID:7 0 0.035
central nervous system disease DOID:331 0 0.012
brain disease DOID:936 0 0.012