Rattus norvegicus

0 known processes

Itgam

integrin, alpha M

(Aliases: Cd11b)

Itgam biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of multicellular organismal process GO:0051241 203 0.848
regulation of signal transduction GO:0009966 318 0.796
Rat
defense response GO:0006952 194 0.754
Mouse Rat
regulation of phosphorus metabolic process GO:0051174 349 0.737
Rat
cellular metal ion homeostasis GO:0006875 172 0.724
positive regulation of multicellular organismal process GO:0051240 387 0.703
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.700
positive regulation of signal transduction GO:0009967 175 0.690
Rat
positive regulation of cell motility GO:2000147 97 0.659
Rat
response to biotic stimulus GO:0009607 226 0.658
cation homeostasis GO:0055080 195 0.643
muscle contraction GO:0006936 88 0.639
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.635
Rat
metal ion homeostasis GO:0055065 186 0.631
regulation of programmed cell death GO:0043067 341 0.607
Rat
homeostatic process GO:0042592 331 0.606
regulation of phosphate metabolic process GO:0019220 349 0.595
Rat
ion homeostasis GO:0050801 212 0.594
cellular response to oxygen containing compound GO:1901701 386 0.585
Rat
cellular calcium ion homeostasis GO:0006874 160 0.585
transcription dna templated GO:0006351 377 0.581
cellular divalent inorganic cation homeostasis GO:0072503 162 0.577
lipid metabolic process GO:0006629 283 0.574
chemical homeostasis GO:0048878 292 0.571
divalent inorganic cation homeostasis GO:0072507 165 0.567
muscle system process GO:0003012 115 0.566
Rat
positive regulation of response to stimulus GO:0048584 285 0.555
Rat
neuron development GO:0048666 286 0.542
Rat
immune system process GO:0002376 204 0.537
Mouse Rat
regulation of mapk cascade GO:0043408 116 0.532
Rat
regulation of multicellular organismal development GO:2000026 376 0.518
positive regulation of signaling GO:0023056 270 0.515
Rat
positive regulation of programmed cell death GO:0043068 157 0.510
Rat
neuron projection morphogenesis GO:0048812 122 0.497
Rat
brain development GO:0007420 247 0.495
Rat
regulation of intracellular signal transduction GO:1902531 218 0.485
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.480
response to external biotic stimulus GO:0043207 221 0.475
cellular cation homeostasis GO:0030003 180 0.474
apoptotic process GO:0006915 381 0.472
Rat
regulation of nervous system development GO:0051960 264 0.470
regulation of transcription dna templated GO:0006355 374 0.466
regulation of secretion GO:0051046 224 0.462
cellular homeostasis GO:0019725 252 0.460
positive regulation of secretion by cell GO:1903532 128 0.458
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.457
inflammatory response GO:0006954 150 0.455
Mouse Rat
regulation of cellular localization GO:0060341 263 0.454
positive regulation of cell proliferation GO:0008284 249 0.452
Rat
secretion by cell GO:0032940 248 0.442
cellular component movement GO:0006928 248 0.435
Mouse Rat
regulation of ion transport GO:0043269 245 0.434
cytosolic calcium ion homeostasis GO:0051480 140 0.429
response to cytokine GO:0034097 215 0.428
programmed cell death GO:0012501 392 0.426
Rat
neuron differentiation GO:0030182 368 0.424
Rat
signal transduction by phosphorylation GO:0023014 144 0.424
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.416
Rat
regulation of apoptotic process GO:0042981 335 0.416
Rat
calcium ion homeostasis GO:0055074 162 0.410
central nervous system development GO:0007417 311 0.401
Mouse Rat
intracellular signal transduction GO:0035556 314 0.398
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.397
Rat
regulation of neurogenesis GO:0050767 247 0.395
cellular ion homeostasis GO:0006873 184 0.389
regulation of cell development GO:0060284 263 0.387
smooth muscle contraction GO:0006939 37 0.385
Rat
cell cell signaling GO:0007267 335 0.379
nucleic acid templated transcription GO:0097659 379 0.379
response to bacterium GO:0009617 200 0.378
cellular chemical homeostasis GO:0055082 247 0.376
regulation of cellular component movement GO:0051270 150 0.375
Rat
secretion GO:0046903 307 0.375
regulation of rna biosynthetic process GO:2001141 381 0.372
regulation of secretion by cell GO:1903530 208 0.368
positive regulation of transport GO:0051050 245 0.368
Rat
positive regulation of cell migration GO:0030335 96 0.358
Rat
positive regulation of cellular component movement GO:0051272 102 0.356
Rat
regulation of rna metabolic process GO:0051252 391 0.353
regulation of cell differentiation GO:0045595 320 0.352
positive regulation of neurogenesis GO:0050769 165 0.338
response to other organism GO:0051707 220 0.333
response to lipopolysaccharide GO:0032496 191 0.328
regulation of kinase activity GO:0043549 117 0.324
Rat
negative regulation of developmental process GO:0051093 125 0.322
angiogenesis GO:0001525 53 0.322
transcription from rna polymerase ii promoter GO:0006366 252 0.320
purine containing compound metabolic process GO:0072521 253 0.320
mesoderm development GO:0007498 2 0.311
negative regulation of cellular metabolic process GO:0031324 281 0.302
regulation of cell proliferation GO:0042127 359 0.286
Rat
cellular response to hormone stimulus GO:0032870 247 0.283
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.281
Rat
cellular response to lipid GO:0071396 201 0.280
Rat
rna biosynthetic process GO:0032774 380 0.275
nitrogen compound transport GO:0071705 229 0.274
positive regulation of cell communication GO:0010647 271 0.267
Rat
positive regulation of cell death GO:0010942 184 0.267
Rat
response to molecule of bacterial origin GO:0002237 194 0.265
positive regulation of mapk cascade GO:0043410 92 0.262
Rat
positive regulation of developmental process GO:0051094 283 0.257
head development GO:0060322 247 0.254
Rat
organophosphate metabolic process GO:0019637 370 0.248
regulation of cellular component organization GO:0051128 368 0.248
Rat
regulation of phosphorylation GO:0042325 248 0.245
Rat
synaptic transmission GO:0007268 235 0.242
regulation of cell migration GO:0030334 128 0.241
Rat
mapk cascade GO:0000165 140 0.239
Rat
cellular response to endogenous stimulus GO:0071495 377 0.239
Rat
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.238
circulatory system development GO:0072359 134 0.235
carboxylic acid metabolic process GO:0019752 289 0.233
sensory perception of pain GO:0019233 73 0.232
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.230
negative regulation of signaling GO:0023057 157 0.230
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.228
regulation of protein metabolic process GO:0051246 289 0.222
Rat
purine nucleotide metabolic process GO:0006163 229 0.222
regulation of nucleic acid templated transcription GO:1903506 380 0.218
g protein coupled receptor signaling pathway GO:0007186 242 0.216
divalent metal ion transport GO:0070838 132 0.215
immune response GO:0006955 104 0.214
locomotion GO:0040011 237 0.212
Mouse Rat
neurological system process GO:0050877 219 0.210
Rat
hormone secretion GO:0046879 115 0.209
regulation of cell motility GO:2000145 131 0.209
Rat
regulation of neuron differentiation GO:0045664 208 0.206
signal release GO:0023061 145 0.206
localization of cell GO:0051674 202 0.205
Mouse Rat
cellular response to cytokine stimulus GO:0071345 127 0.204
response to nutrient levels GO:0031667 370 0.204
Rat
cellular response to nitrogen compound GO:1901699 210 0.202
positive regulation of biosynthetic process GO:0009891 319 0.202
Rat
positive regulation of cell differentiation GO:0045597 217 0.200
negative regulation of response to stimulus GO:0048585 155 0.200
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.199
Rat
regulation of system process GO:0044057 208 0.198
Rat
response to extracellular stimulus GO:0009991 380 0.196
Rat
anatomical structure formation involved in morphogenesis GO:0048646 83 0.193
organic anion transport GO:0015711 132 0.190
positive regulation of gene expression GO:0010628 244 0.188
Rat
positive regulation of secretion GO:0051047 140 0.185
anion transport GO:0006820 178 0.183
anatomical structure morphogenesis GO:0009653 298 0.180
Rat
organic acid transport GO:0015849 116 0.177
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.176
hormone transport GO:0009914 121 0.175
negative regulation of signal transduction GO:0009968 83 0.174
positive regulation of phosphorylation GO:0042327 177 0.170
Rat
response to corticosteroid GO:0031960 235 0.170
cell projection organization GO:0030030 302 0.169
Rat
negative regulation of cell communication GO:0010648 158 0.167
positive regulation of apoptotic process GO:0043065 154 0.167
Rat
negative regulation of biosynthetic process GO:0009890 168 0.166
circulatory system process GO:0003013 183 0.165
Rat
feeding behavior GO:0007631 53 0.164
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.159
organic acid metabolic process GO:0006082 292 0.158
regulation of neuron projection development GO:0010975 161 0.157
response to mechanical stimulus GO:0009612 134 0.156
Rat
salivary gland morphogenesis GO:0007435 1 0.155
calcium ion transport GO:0006816 131 0.155
divalent inorganic cation transport GO:0072511 134 0.153
regulation of immune system process GO:0002682 123 0.150
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.149
cell type specific apoptotic process GO:0097285 134 0.146
Rat
negative regulation of growth GO:0045926 37 0.143
regulation of blood pressure GO:0008217 83 0.143
forebrain development GO:0030900 98 0.141
regulation of molecular function GO:0065009 398 0.141
Rat
ribonucleotide metabolic process GO:0009259 231 0.141
response to peptide GO:1901652 292 0.140
rna metabolic process GO:0016070 406 0.140
macromolecule localization GO:0033036 252 0.140
Rat
nucleotide metabolic process GO:0009117 279 0.139
organophosphate biosynthetic process GO:0090407 143 0.138
neutrophil migration GO:1990266 12 0.137
Mouse
regulation of hormone secretion GO:0046883 106 0.136
amino acid transport GO:0006865 70 0.135
cellular lipid metabolic process GO:0044255 208 0.135
positive regulation of catalytic activity GO:0043085 184 0.133
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.132
regulation of catalytic activity GO:0050790 304 0.131
Rat
neuron death GO:0070997 127 0.130
Rat
positive regulation of nervous system development GO:0051962 178 0.130
positive regulation of rna biosynthetic process GO:1902680 197 0.129
regulation of hormone levels GO:0010817 187 0.128
response to hypoxia GO:0001666 231 0.127
Rat
regulation of response to wounding GO:1903034 69 0.127
Rat
response to oxygen levels GO:0070482 265 0.126
Rat
reproductive process GO:0022414 372 0.125
Rat Fly
ribose phosphate metabolic process GO:0019693 235 0.125
taxis GO:0042330 67 0.125
Mouse Rat
neuron projection development GO:0031175 273 0.124
Rat
cation transport GO:0006812 382 0.124
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.121
response to wounding GO:0009611 254 0.120
Rat
myeloid leukocyte migration GO:0097529 20 0.120
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.120
blood vessel morphogenesis GO:0048514 58 0.120
aging GO:0007568 241 0.119
stress activated protein kinase signaling cascade GO:0031098 37 0.119
adenosine receptor signaling pathway GO:0001973 7 0.119
regulation of synaptic transmission GO:0050804 141 0.118
sensory perception GO:0007600 101 0.118
Rat
ribonucleotide catabolic process GO:0009261 136 0.117
muscle cell proliferation GO:0033002 84 0.116
Rat
positive regulation of behavior GO:0048520 38 0.116
Rat
hematopoietic or lymphoid organ development GO:0048534 36 0.115
Mouse
regulation of anatomical structure size GO:0090066 135 0.114
Rat
single organism cellular localization GO:1902580 102 0.114
nucleobase containing small molecule metabolic process GO:0055086 316 0.113
response to estradiol GO:0032355 164 0.113
Rat
protein localization GO:0008104 191 0.113
Rat
positive regulation of protein metabolic process GO:0051247 178 0.111
Rat
gland development GO:0048732 155 0.110
Rat
renal system process GO:0003014 40 0.110
positive regulation of cell development GO:0010720 176 0.110
cellular response to peptide hormone stimulus GO:0071375 120 0.110
regulation of cell activation GO:0050865 50 0.109
response to estrogen GO:0043627 232 0.109
Rat
cell motility GO:0048870 202 0.109
Mouse Rat
positive regulation of rna metabolic process GO:0051254 203 0.108
cytokine mediated signaling pathway GO:0019221 43 0.106
negative regulation of programmed cell death GO:0043069 183 0.105
regulation of metal ion transport GO:0010959 118 0.105
positive regulation of protein phosphorylation GO:0001934 135 0.105
Rat
cellular response to stress GO:0033554 269 0.104
negative regulation of metabolic process GO:0009892 331 0.103
regulation of muscle system process GO:0090257 79 0.103
Rat
positive regulation of ion transport GO:0043270 94 0.103
regulation of anatomical structure morphogenesis GO:0022603 141 0.102
cell projection morphogenesis GO:0048858 123 0.100
Rat
response to growth factor GO:0070848 189 0.098
activation of mapkk activity GO:0000186 18 0.098
negative regulation of apoptotic process GO:0043066 181 0.098
regulation of cellular protein metabolic process GO:0032268 267 0.097
Rat
multicellular organismal reproductive process GO:0048609 233 0.096
Fly
purine nucleotide biosynthetic process GO:0006164 83 0.096
cellular component morphogenesis GO:0032989 155 0.096
Rat
peptidyl amino acid modification GO:0018193 126 0.096
catabolic process GO:0009056 351 0.095
organ morphogenesis GO:0009887 75 0.095
Rat
cellular amino acid metabolic process GO:0006520 107 0.094
monocarboxylic acid metabolic process GO:0032787 152 0.094
regulation of protein phosphorylation GO:0001932 183 0.094
Rat
granulocyte migration GO:0097530 16 0.093
Mouse
protein transport GO:0015031 132 0.093
negative regulation of nervous system development GO:0051961 79 0.092
cellular response to organonitrogen compound GO:0071417 197 0.092
negative regulation of neuron apoptotic process GO:0043524 45 0.092
cellular response to organic cyclic compound GO:0071407 202 0.092
Rat
oxoacid metabolic process GO:0043436 290 0.091
regulation of protein modification process GO:0031399 194 0.091
Rat
carboxylic acid transport GO:0046942 115 0.090
organic substance catabolic process GO:1901575 316 0.090
regulation of vasculature development GO:1901342 44 0.090
peptidyl tyrosine phosphorylation GO:0018108 72 0.089
multicellular organismal homeostasis GO:0048871 49 0.089
positive regulation of immune system process GO:0002684 90 0.088
Rat
tissue development GO:0009888 252 0.087
Human Rat
cellular carbohydrate metabolic process GO:0044262 72 0.087
cellular catabolic process GO:0044248 295 0.087
regulation of calcium ion transport GO:0051924 77 0.086
heart process GO:0003015 57 0.086
positive regulation of nucleic acid templated transcription GO:1903508 197 0.085
positive regulation of transferase activity GO:0051347 81 0.084
Rat
negative regulation of phosphorus metabolic process GO:0010563 80 0.084
regulation of cellular amino acid metabolic process GO:0006521 2 0.083
positive regulation of locomotion GO:0040017 102 0.083
Rat
response to radiation GO:0009314 137 0.082
organ regeneration GO:0031100 101 0.082
response to insulin GO:0032868 133 0.080
erk1 and erk2 cascade GO:0070371 48 0.080
regulation of transferase activity GO:0051338 123 0.080
Rat
positive regulation of protein modification process GO:0031401 142 0.080
Rat
response to glucocorticoid GO:0051384 223 0.079
reactive oxygen species metabolic process GO:0072593 37 0.079
response to tumor necrosis factor GO:0034612 56 0.079
response to metal ion GO:0010038 253 0.079
single organism reproductive process GO:0044702 297 0.078
Fly
dicarboxylic acid transport GO:0006835 34 0.078
positive regulation of molecular function GO:0044093 230 0.078
Rat
cell migration GO:0016477 197 0.078
Mouse Rat
startle response GO:0001964 2 0.078
blood vessel development GO:0001568 69 0.077
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.077
cellular response to molecule of bacterial origin GO:0071219 56 0.077
purine containing compound catabolic process GO:0072523 138 0.077
dendrite morphogenesis GO:0048813 43 0.077
negative regulation of neuron differentiation GO:0045665 62 0.076
carbohydrate derivative catabolic process GO:1901136 147 0.076
cardiovascular system development GO:0072358 134 0.075
protein complex subunit organization GO:0071822 302 0.075
response to ketone GO:1901654 182 0.074
developmental process involved in reproduction GO:0003006 159 0.074
Fly
single organism organelle organization GO:1902589 180 0.074
purine ribonucleotide metabolic process GO:0009150 227 0.073
cellular response to tumor necrosis factor GO:0071356 46 0.073
amine transport GO:0015837 57 0.073
gastrulation GO:0007369 2 0.073
positive regulation of cellular amine metabolic process GO:0033240 3 0.071
regulation of nucleotide metabolic process GO:0006140 117 0.071
protein phosphorylation GO:0006468 345 0.071
Rat
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.071
cognition GO:0050890 92 0.070
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.070
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.069
neuron apoptotic process GO:0051402 88 0.068
Rat
response to peptide hormone GO:0043434 278 0.068
behavior GO:0007610 205 0.067
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.067
regulation of neurological system process GO:0031644 43 0.067
Rat
cellular component biogenesis GO:0044085 368 0.066
Rat
striated muscle contraction GO:0006941 44 0.066
single organism behavior GO:0044708 130 0.066
complement receptor mediated signaling pathway GO:0002430 2 0.066
glycosyl compound metabolic process GO:1901657 182 0.066
heterocycle catabolic process GO:0046700 167 0.065
nucleoside phosphate catabolic process GO:1901292 140 0.065
response to carbohydrate GO:0009743 183 0.065
Rat
nucleoside catabolic process GO:0009164 126 0.064
synapse organization GO:0050808 46 0.064
negative regulation of cell death GO:0060548 229 0.064
vasculature development GO:0001944 70 0.063
exocytosis GO:0006887 60 0.063
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.062
actin filament based process GO:0030029 86 0.062
single organism biosynthetic process GO:0044711 342 0.062
Rat
norepinephrine secretion GO:0048243 16 0.062
renal sodium excretion GO:0035812 20 0.061
enzyme linked receptor protein signaling pathway GO:0007167 116 0.061
glycosyl compound catabolic process GO:1901658 126 0.061
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.061
g protein coupled purinergic receptor signaling pathway GO:0035588 8 0.061
single organism catabolic process GO:0044712 283 0.061
epithelium development GO:0060429 96 0.061
Rat
acid secretion GO:0046717 48 0.061
positive regulation of protein kinase activity GO:0045860 73 0.061
Rat
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.060
activation of protein kinase activity GO:0032147 47 0.060
Rat
regulation of homeostatic process GO:0032844 101 0.060
vascular process in circulatory system GO:0003018 96 0.060
Rat
myeloid leukocyte activation GO:0002274 36 0.060
ribonucleoside metabolic process GO:0009119 174 0.059
guanosine containing compound metabolic process GO:1901068 74 0.059
cellular response to lipopolysaccharide GO:0071222 55 0.059
regulation of cell projection organization GO:0031344 175 0.059
Rat
negative regulation of neurogenesis GO:0050768 78 0.058
cellular ketone metabolic process GO:0042180 51 0.058
regulation of jnk cascade GO:0046328 19 0.058
response to alkaloid GO:0043279 132 0.058
immune system development GO:0002520 41 0.058
Mouse
defense response to other organism GO:0098542 17 0.058
regulation of neuron death GO:1901214 115 0.057
Rat
regulation of peptide transport GO:0090087 87 0.057
positive regulation of cellular protein metabolic process GO:0032270 167 0.057
Rat
learning or memory GO:0007611 90 0.057
cell growth GO:0016049 104 0.057
Fly
cellular response to growth factor stimulus GO:0071363 162 0.056
negative regulation of gene expression GO:0010629 199 0.056
nucleoside triphosphate metabolic process GO:0009141 144 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.056
single organism intracellular transport GO:1902582 166 0.056
dendrite development GO:0016358 72 0.056
macrophage chemotaxis GO:0048246 2 0.055
purine ribonucleotide biosynthetic process GO:0009152 81 0.055
ribonucleoside triphosphate metabolic process GO:0009199 141 0.055
intracellular transport GO:0046907 185 0.054
regulation of synaptic plasticity GO:0048167 70 0.054
regulation of membrane potential GO:0042391 110 0.054
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.054
macromolecular complex subunit organization GO:0043933 339 0.054
regulation of behavior GO:0050795 61 0.054
Rat
glutamate secretion GO:0014047 19 0.053
gliogenesis GO:0042063 93 0.053
Mouse
regulation of body fluid levels GO:0050878 90 0.053
Rat
purine nucleotide catabolic process GO:0006195 136 0.053
endocytosis GO:0006897 84 0.053
Rat
positive regulation of transcription dna templated GO:0045893 197 0.052
amine metabolic process GO:0009308 38 0.052
organic hydroxy compound metabolic process GO:1901615 115 0.051
anterior posterior pattern specification GO:0009952 1 0.051
purine ribonucleoside metabolic process GO:0046128 168 0.051
regulation of cellular amine metabolic process GO:0033238 8 0.051
nucleoside phosphate metabolic process GO:0006753 283 0.051
negative regulation of phosphate metabolic process GO:0045936 80 0.051
cellular response to external stimulus GO:0071496 118 0.051
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.051
muscle tissue development GO:0060537 58 0.050
Rat
regulation of muscle contraction GO:0006937 53 0.050
Rat
organelle organization GO:0006996 266 0.050
regulation of leukocyte differentiation GO:1902105 20 0.050
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.050
regulation of potassium ion transport GO:0043266 29 0.050
cytokine biosynthetic process GO:0042089 3 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.049
heart contraction GO:0060047 57 0.049
cellular response to biotic stimulus GO:0071216 59 0.049
regeneration GO:0031099 163 0.048
organonitrogen compound catabolic process GO:1901565 179 0.048
negative regulation of developmental growth GO:0048640 15 0.048
purine nucleoside metabolic process GO:0042278 169 0.048
negative regulation of cell proliferation GO:0008285 119 0.047
positive regulation of blood circulation GO:1903524 65 0.047
nucleoside phosphate biosynthetic process GO:1901293 102 0.047
cellular response to abiotic stimulus GO:0071214 85 0.047
Rat
cytoskeleton organization GO:0007010 111 0.046
neurotrophin production GO:0032898 2 0.046
stress activated mapk cascade GO:0051403 35 0.046
single organism cell adhesion GO:0098602 46 0.046
Mouse Rat
peptidyl tyrosine modification GO:0018212 72 0.045
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.045
response to toxic substance GO:0009636 133 0.045
prepulse inhibition GO:0060134 1 0.045
carbohydrate metabolic process GO:0005975 130 0.045
cellular response to insulin stimulus GO:0032869 81 0.045
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.044
lymphoid progenitor cell differentiation GO:0002320 2 0.044
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.044
regulation of protein localization GO:0032880 81 0.044
actin cytoskeleton organization GO:0030036 73 0.044
digestive system development GO:0055123 41 0.044
regulation of amine transport GO:0051952 54 0.043
negative regulation of circadian sleep wake cycle sleep GO:0042321 5 0.043
amide transport GO:0042886 105 0.043
regulation of hydrolase activity GO:0051336 143 0.043
Rat
positive regulation of immune response GO:0050778 42 0.043
proteolysis GO:0006508 175 0.043
response to heat GO:0009408 60 0.042
vesicle mediated transport GO:0016192 181 0.042
Rat
regulation of locomotion GO:0040012 148 0.042
Rat
regulation of erk1 and erk2 cascade GO:0070372 41 0.042
cellular amine metabolic process GO:0044106 38 0.041
negative regulation of macromolecule metabolic process GO:0010605 260 0.041
cellular component assembly GO:0022607 360 0.041
Rat
negative regulation of chronic inflammatory response GO:0002677 2 0.041
purine nucleoside triphosphate catabolic process GO:0009146 122 0.041
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.041
protein secretion GO:0009306 34 0.040
regulation of blood circulation GO:1903522 110 0.040
response to mineralocorticoid GO:0051385 49 0.040
cell morphogenesis involved in differentiation GO:0000904 119 0.040
leukocyte migration GO:0050900 38 0.040
Mouse Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.040
nucleoside triphosphate catabolic process GO:0009143 123 0.040
negative regulation of ion transport GO:0043271 51 0.039
nucleotide catabolic process GO:0009166 139 0.039
positive regulation of nucleotide metabolic process GO:0045981 91 0.039
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.039
neuropeptide signaling pathway GO:0007218 29 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
regulation of neuron apoptotic process GO:0043523 83 0.039
Rat
response to decreased oxygen levels GO:0036293 237 0.038
Rat
negative regulation of circadian sleep wake cycle non rem sleep GO:0042323 2 0.038
blood circulation GO:0008015 183 0.038
Rat
catecholamine secretion GO:0050432 33 0.038
negative regulation of amine transport GO:0051953 24 0.037
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.037
detection of stimulus GO:0051606 24 0.037
Rat
positive regulation of cellular component organization GO:0051130 200 0.037
Rat
multi organism reproductive process GO:0044703 262 0.037
Rat Fly
negative regulation of transport GO:0051051 136 0.036
purine ribonucleotide catabolic process GO:0009154 136 0.036
immune response regulating signaling pathway GO:0002764 19 0.036
positive regulation of hydrolase activity GO:0051345 86 0.036
Rat
positive regulation of kinase activity GO:0033674 77 0.036
Rat
formation of primary germ layer GO:0001704 1 0.035
multicellular organism growth GO:0035264 1 0.035
jak stat cascade GO:0007259 26 0.035
kidney development GO:0001822 67 0.035
positive regulation of neuron differentiation GO:0045666 126 0.035
tumor necrosis factor superfamily cytokine production GO:0071706 13 0.035
reactive nitrogen species metabolic process GO:2001057 1 0.035
peptide transport GO:0015833 97 0.035
regulation of smooth muscle contraction GO:0006940 29 0.034
Rat
ribonucleoside triphosphate catabolic process GO:0009203 122 0.034
insulin receptor signaling pathway GO:0008286 24 0.034
response to acid chemical GO:0001101 222 0.034
Rat
positive regulation of jnk cascade GO:0046330 13 0.034
regulation of cell growth GO:0001558 85 0.034
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.034
embryonic pattern specification GO:0009880 1 0.034
granulocyte chemotaxis GO:0071621 15 0.033
Mouse
regulation of cytokine production GO:0001817 56 0.033
ribose phosphate biosynthetic process GO:0046390 87 0.033
positive regulation of synaptic transmission GO:0050806 62 0.033
negative regulation of transcription dna templated GO:0045892 116 0.033

Itgam disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.074
cancer DOID:162 0 0.074
disease of cellular proliferation DOID:14566 0 0.074
organ system cancer DOID:0050686 0 0.074
retinal disease DOID:5679 0 0.062
retinal degeneration DOID:8466 0 0.062
sensory system disease DOID:0050155 0 0.062
disease of anatomical entity DOID:7 0 0.062
Human
eye and adnexa disease DOID:1492 0 0.062
nervous system disease DOID:863 0 0.062
eye disease DOID:5614 0 0.062