Rattus norvegicus

96 known processes

Itpka

inositol 1,4,5-trisphosphate 3-kinase A

Itpka biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.378
response to nutrient levels GO:0031667 370 0.281
organic substance catabolic process GO:1901575 316 0.226
catabolic process GO:0009056 351 0.203
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.199
oxoacid metabolic process GO:0043436 290 0.159
response to toxic substance GO:0009636 133 0.153
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.152
apoptotic process GO:0006915 381 0.150
response to extracellular stimulus GO:0009991 380 0.148
positive regulation of biosynthetic process GO:0009891 319 0.124
organic acid metabolic process GO:0006082 292 0.121
synaptic transmission GO:0007268 235 0.119
single organism catabolic process GO:0044712 283 0.108
vesicle mediated transport GO:0016192 181 0.107
regulation of intracellular signal transduction GO:1902531 218 0.099
regulation of phosphate metabolic process GO:0019220 349 0.097
glycerolipid metabolic process GO:0046486 67 0.097
regulation of signal transduction GO:0009966 318 0.087
response to external biotic stimulus GO:0043207 221 0.086
cellular amino acid metabolic process GO:0006520 107 0.083
heterocycle catabolic process GO:0046700 167 0.081
regulation of multicellular organismal development GO:2000026 376 0.081
aromatic compound catabolic process GO:0019439 168 0.080
regulation of phosphorus metabolic process GO:0051174 349 0.080
response to oxidative stress GO:0006979 186 0.079
Fly
purine nucleotide metabolic process GO:0006163 229 0.078
regulation of molecular function GO:0065009 398 0.078
neuron death GO:0070997 127 0.075
regulation of hydrolase activity GO:0051336 143 0.071
oxidation reduction process GO:0055114 304 0.070
positive regulation of cellular biosynthetic process GO:0031328 295 0.069
response to biotic stimulus GO:0009607 226 0.068
macromolecular complex subunit organization GO:0043933 339 0.066
regulation of catalytic activity GO:0050790 304 0.065
purine containing compound catabolic process GO:0072523 138 0.065
cellular component biogenesis GO:0044085 368 0.063
ribonucleoside triphosphate metabolic process GO:0009199 141 0.062
rhythmic process GO:0048511 156 0.061
nucleoside triphosphate metabolic process GO:0009141 144 0.060
aging GO:0007568 241 0.060
ion transmembrane transport GO:0034220 365 0.059
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.058
response to decreased oxygen levels GO:0036293 237 0.056
gtp catabolic process GO:0006184 71 0.056
response to hypoxia GO:0001666 231 0.055
nucleic acid templated transcription GO:0097659 379 0.054
transcription dna templated GO:0006351 377 0.053
protein localization GO:0008104 191 0.053
protein complex subunit organization GO:0071822 302 0.053
cellular nitrogen compound catabolic process GO:0044270 163 0.052
regulation of cellular catabolic process GO:0031329 101 0.051
nucleoside phosphate metabolic process GO:0006753 283 0.051
positive regulation of molecular function GO:0044093 230 0.051
gtp metabolic process GO:0046039 72 0.051
rna metabolic process GO:0016070 406 0.050
cellular catabolic process GO:0044248 295 0.050
carbohydrate derivative catabolic process GO:1901136 147 0.050
cellular response to hormone stimulus GO:0032870 247 0.049
response to nutrient GO:0007584 248 0.049
regulation of system process GO:0044057 208 0.048
regulation of protein modification process GO:0031399 194 0.048
cellular response to nitrogen compound GO:1901699 210 0.048
head development GO:0060322 247 0.048
endocytosis GO:0006897 84 0.048
organophosphate metabolic process GO:0019637 370 0.047
Fly
nucleoside catabolic process GO:0009164 126 0.047
purine nucleoside triphosphate catabolic process GO:0009146 122 0.047
response to insulin GO:0032868 133 0.047
amine metabolic process GO:0009308 38 0.047
protein heterooligomerization GO:0051291 89 0.047
organonitrogen compound catabolic process GO:1901565 179 0.046
growth GO:0040007 165 0.046
cellular response to peptide GO:1901653 133 0.046
positive regulation of transport GO:0051050 245 0.046
response to estrogen GO:0043627 232 0.046
cellular homeostasis GO:0019725 252 0.046
regulation of cellular amino acid metabolic process GO:0006521 2 0.045
rna biosynthetic process GO:0032774 380 0.045
inorganic cation transmembrane transport GO:0098662 202 0.044
response to acid chemical GO:0001101 222 0.044
nucleobase containing compound catabolic process GO:0034655 152 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.044
peptidyl amino acid modification GO:0018193 126 0.044
nucleoside triphosphate catabolic process GO:0009143 123 0.043
cell cell signaling GO:0007267 335 0.043
cellular component assembly GO:0022607 360 0.043
regulation of synaptic transmission GO:0050804 141 0.043
transmembrane transport GO:0055085 412 0.042
purine ribonucleotide catabolic process GO:0009154 136 0.042
protein complex assembly GO:0006461 263 0.042
neuron differentiation GO:0030182 368 0.042
guanosine containing compound catabolic process GO:1901069 71 0.042
positive regulation of apoptotic process GO:0043065 154 0.041
macromolecular complex assembly GO:0065003 273 0.041
inorganic ion transmembrane transport GO:0098660 229 0.041
nucleotide catabolic process GO:0009166 139 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.040
single organism biosynthetic process GO:0044711 342 0.039
Fly
response to lipopolysaccharide GO:0032496 191 0.039
multicellular organism growth GO:0035264 1 0.039
nucleotide metabolic process GO:0009117 279 0.039
metal ion transport GO:0030001 289 0.039
protein oligomerization GO:0051259 191 0.039
positive regulation of catalytic activity GO:0043085 184 0.039
cellular amine metabolic process GO:0044106 38 0.039
response to wounding GO:0009611 254 0.039
response to ethanol GO:0045471 162 0.038
neuron apoptotic process GO:0051402 88 0.038
response to amino acid GO:0043200 75 0.037
reproductive process GO:0022414 372 0.037
positive regulation of signal transduction GO:0009967 175 0.037
phospholipid metabolic process GO:0006644 61 0.036
developmental process involved in reproduction GO:0003006 159 0.036
positive regulation of intracellular signal transduction GO:1902533 138 0.036
response to estradiol GO:0032355 164 0.036
cellular response to organic cyclic compound GO:0071407 202 0.036
negative regulation of cell death GO:0060548 229 0.035
small gtpase mediated signal transduction GO:0007264 36 0.035
purine ribonucleoside catabolic process GO:0046130 124 0.035
positive regulation of protein metabolic process GO:0051247 178 0.035
regulation of nucleoside metabolic process GO:0009118 66 0.035
regulation of apoptotic process GO:0042981 335 0.035
organophosphate catabolic process GO:0046434 148 0.034
purine nucleoside metabolic process GO:0042278 169 0.034
response to oxygen levels GO:0070482 265 0.034
ribose phosphate metabolic process GO:0019693 235 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.033
somatostatin signaling pathway GO:0038170 4 0.033
purine containing compound metabolic process GO:0072521 253 0.033
chemical homeostasis GO:0048878 292 0.033
nucleoside metabolic process GO:0009116 179 0.033
positive regulation of cell death GO:0010942 184 0.033
regulation of cellular amine metabolic process GO:0033238 8 0.033
cellular response to oxygen containing compound GO:1901701 386 0.032
response to peptide GO:1901652 292 0.032
response to inorganic substance GO:0010035 377 0.032
l glutamate import GO:0051938 2 0.031
nucleoside phosphate catabolic process GO:1901292 140 0.031
reproduction GO:0000003 245 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.030
response to vitamin GO:0033273 131 0.030
response to carbohydrate GO:0009743 183 0.030
guanosine containing compound metabolic process GO:1901068 74 0.030
regulation of programmed cell death GO:0043067 341 0.030
defense response GO:0006952 194 0.030
regulation of purine nucleotide metabolic process GO:1900542 115 0.030
ribonucleoside metabolic process GO:0009119 174 0.030
homeostatic process GO:0042592 331 0.030
regulation of vesicle mediated transport GO:0060627 81 0.030
intracellular signal transduction GO:0035556 314 0.030
negative regulation of metabolic process GO:0009892 331 0.030
ribonucleotide metabolic process GO:0009259 231 0.030
regulation of protein metabolic process GO:0051246 289 0.029
response to other organism GO:0051707 220 0.029
regulation of rna metabolic process GO:0051252 391 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
organic cyclic compound catabolic process GO:1901361 175 0.029
single organism reproductive process GO:0044702 297 0.029
response to hydrogen peroxide GO:0042542 89 0.028
response to molecule of bacterial origin GO:0002237 194 0.028
organelle organization GO:0006996 266 0.028
response to starvation GO:0042594 59 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.028
circulatory system process GO:0003013 183 0.027
regulation of membrane potential GO:0042391 110 0.027
programmed cell death GO:0012501 392 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
glutamate receptor signaling pathway GO:0007215 43 0.027
cation transport GO:0006812 382 0.027
regulation of catabolic process GO:0009894 113 0.026
organonitrogen compound biosynthetic process GO:1901566 167 0.026
multicellular organism reproduction GO:0032504 233 0.026
cellular response to stress GO:0033554 269 0.026
regulation of nucleotide metabolic process GO:0006140 117 0.026
protein autophosphorylation GO:0046777 66 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
purine ribonucleoside metabolic process GO:0046128 168 0.025
response to peptide hormone GO:0043434 278 0.025
response to glucocorticoid GO:0051384 223 0.025
ribonucleoside catabolic process GO:0042454 126 0.025
response to ketone GO:1901654 182 0.025
lipid metabolic process GO:0006629 283 0.025
regulation of blood circulation GO:1903522 110 0.024
cellular glucan metabolic process GO:0006073 23 0.024
ras protein signal transduction GO:0007265 29 0.024
protein complex biogenesis GO:0070271 263 0.024
regulation of neuron apoptotic process GO:0043523 83 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
response to monosaccharide GO:0034284 159 0.024
single organism organelle organization GO:1902589 180 0.024
cellular response to organonitrogen compound GO:0071417 197 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.023
intracellular transport GO:0046907 185 0.023
regulation of cellular component organization GO:0051128 368 0.023
regulation of transporter activity GO:0032409 50 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
cellular response to peptide hormone stimulus GO:0071375 120 0.023
ribonucleotide catabolic process GO:0009261 136 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
alpha amino acid biosynthetic process GO:1901607 23 0.023
regulation of neuron projection development GO:0010975 161 0.023
cellular ketone metabolic process GO:0042180 51 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
locomotion GO:0040011 237 0.023
response to food GO:0032094 27 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
purine nucleotide catabolic process GO:0006195 136 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.022
proteolysis GO:0006508 175 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
blood circulation GO:0008015 183 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
brain development GO:0007420 247 0.021
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.021
neuron development GO:0048666 286 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
dendritic spine morphogenesis GO:0060997 9 0.021
response to transition metal nanoparticle GO:1990267 122 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
regulation of phosphorylation GO:0042325 248 0.020
cytoskeleton organization GO:0007010 111 0.020
secretion GO:0046903 307 0.020
regulation of endocytosis GO:0030100 42 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
behavior GO:0007610 205 0.020
regulation of growth GO:0040008 105 0.020
female sex differentiation GO:0046660 59 0.020
regulation of tube size GO:0035150 89 0.020
protein transport GO:0015031 132 0.020
glycerophospholipid metabolic process GO:0006650 47 0.020
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.020
negative regulation of apoptotic process GO:0043066 181 0.019
positive regulation of gtp catabolic process GO:0033126 48 0.019
cell type specific apoptotic process GO:0097285 134 0.019
response to ammonium ion GO:0060359 71 0.019
regulation of gtpase activity GO:0043087 57 0.019
wound healing GO:0042060 122 0.019
generation of precursor metabolites and energy GO:0006091 62 0.019
ion homeostasis GO:0050801 212 0.019
response to cytokine GO:0034097 215 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
cardiac muscle cell contraction GO:0086003 10 0.019
regulation of transcription dna templated GO:0006355 374 0.018
response to hexose GO:0009746 144 0.018
positive regulation of hydrolase activity GO:0051345 86 0.018
response to bacterium GO:0009617 200 0.018
multi organism reproductive process GO:0044703 262 0.018
cation transmembrane transport GO:0098655 263 0.018
bmp signaling pathway GO:0030509 4 0.018
respiratory gaseous exchange GO:0007585 4 0.018
neurological system process GO:0050877 219 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
sex differentiation GO:0007548 113 0.018
gastrulation GO:0007369 2 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.018
regulation of homeostatic process GO:0032844 101 0.017
regulation of anatomical structure size GO:0090066 135 0.017
embryo development GO:0009790 49 0.017
protein phosphorylation GO:0006468 345 0.017
single organism behavior GO:0044708 130 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
smooth muscle cell proliferation GO:0048659 77 0.017
sodium ion transport GO:0006814 82 0.017
positive regulation of nucleoside metabolic process GO:0045979 55 0.017
asymmetric protein localization GO:0008105 2 0.017
cellular chemical homeostasis GO:0055082 247 0.017
regulation of kinase activity GO:0043549 117 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
negative regulation of signaling GO:0023057 157 0.016
cellular response to alcohol GO:0097306 87 0.016
regulation of neuron death GO:1901214 115 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
negative regulation of molecular function GO:0044092 133 0.016
regulation of protein kinase activity GO:0045859 105 0.016
cellular response to oxidative stress GO:0034599 76 0.016
vascular process in circulatory system GO:0003018 96 0.016
response to glucose GO:0009749 136 0.016
response to amine GO:0014075 46 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
respiratory system process GO:0003016 3 0.015
positive regulation of cell communication GO:0010647 271 0.015
positive regulation of gtpase activity GO:0043547 47 0.015
actin filament based process GO:0030029 86 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
sensory organ development GO:0007423 74 0.015
positive regulation of gene expression GO:0010628 244 0.015
positive regulation of protein modification process GO:0031401 142 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.015
regulation of cell development GO:0060284 263 0.015
energy reserve metabolic process GO:0006112 25 0.015
neuron projection development GO:0031175 273 0.015
negative regulation of signal transduction GO:0009968 83 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
positive regulation of nucleotide catabolic process GO:0030813 53 0.015
cellular ion homeostasis GO:0006873 184 0.015
regulation of sodium ion transport GO:0002028 21 0.015
ovulation cycle GO:0042698 67 0.015
cellular amino acid biosynthetic process GO:0008652 32 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
neurotransmitter uptake GO:0001504 3 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
polysaccharide metabolic process GO:0005976 25 0.014
regulation of ion transmembrane transport GO:0034765 121 0.014
macromolecule catabolic process GO:0009057 58 0.014
response to antibiotic GO:0046677 39 0.014
anion transmembrane transport GO:0098656 77 0.014
cgmp biosynthetic process GO:0006182 15 0.014
positive regulation of growth GO:0045927 55 0.014
protein homooligomerization GO:0051260 91 0.014
regulation of cell differentiation GO:0045595 320 0.014
membrane hyperpolarization GO:0060081 11 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
Fly
negative regulation of ion transmembrane transporter activity GO:0032413 12 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
negative regulation of innate immune response GO:0045824 4 0.013
negative regulation of cell communication GO:0010648 158 0.013
regulation of transmembrane transporter activity GO:0022898 49 0.013
lipid biosynthetic process GO:0008610 128 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
positive regulation of signaling GO:0023056 270 0.013
cellular component movement GO:0006928 248 0.013
cellular protein localization GO:0034613 122 0.013
metal ion homeostasis GO:0055065 186 0.013
regulation of erk1 and erk2 cascade GO:0070372 41 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
regulation of small gtpase mediated signal transduction GO:0051056 48 0.013
gamete generation GO:0007276 124 0.013
regulation of neurogenesis GO:0050767 247 0.013
activation of protein kinase activity GO:0032147 47 0.013
protein localization to organelle GO:0033365 57 0.013
cellular lipid metabolic process GO:0044255 208 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
hepaticobiliary system development GO:0061008 90 0.012
response to camp GO:0051591 91 0.012
response to corticosteroid GO:0031960 235 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
dephosphorylation GO:0016311 98 0.012
cellular response to external stimulus GO:0071496 118 0.012
positive regulation of long term synaptic potentiation GO:1900273 4 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
regeneration GO:0031099 163 0.012
response to cocaine GO:0042220 39 0.012
dna metabolic process GO:0006259 96 0.012
sexual reproduction GO:0019953 148 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
neurotransmitter transport GO:0006836 42 0.012
single organism intracellular transport GO:1902582 166 0.012
anterior posterior pattern specification GO:0009952 1 0.012
establishment of protein localization GO:0045184 141 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
response to metal ion GO:0010038 253 0.012
positive regulation of secretion GO:0051047 140 0.012
involuntary skeletal muscle contraction GO:0003011 2 0.012
regulation of gtp catabolic process GO:0033124 58 0.012
positive regulation of membrane potential GO:0045838 16 0.012
cellular response to nutrient levels GO:0031669 60 0.011
liver development GO:0001889 90 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
dna replication GO:0006260 37 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
regulation of mapk cascade GO:0043408 116 0.011
response to reactive oxygen species GO:0000302 120 0.011
rho protein signal transduction GO:0007266 11 0.011
n methyl d aspartate receptor clustering GO:0097114 2 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
establishment of tissue polarity GO:0007164 2 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
development of primary female sexual characteristics GO:0046545 56 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
response to purine containing compound GO:0014074 126 0.011
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.011
retina morphogenesis in camera type eye GO:0060042 1 0.011
regulation of ion transport GO:0043269 245 0.011
response to activity GO:0014823 73 0.011
response to mineralocorticoid GO:0051385 49 0.011
tissue development GO:0009888 252 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of dna metabolic process GO:0051052 60 0.011
somatostatin receptor signaling pathway GO:0038169 4 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
response to electrical stimulus GO:0051602 56 0.011
lipid catabolic process GO:0016042 46 0.011
glycogen metabolic process GO:0005977 23 0.011
divalent metal ion transport GO:0070838 132 0.011
ovulation cycle process GO:0022602 50 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
organic anion transport GO:0015711 132 0.010
regulation of metal ion transport GO:0010959 118 0.010
sensory perception GO:0007600 101 0.010
gonad development GO:0008406 104 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
regulation of vascular smooth muscle contraction GO:0003056 3 0.010
synapse assembly GO:0007416 29 0.010
positive regulation of catabolic process GO:0009896 78 0.010
regulation of blood vessel size GO:0050880 89 0.010
dendritic spine development GO:0060996 20 0.010
membrane depolarization GO:0051899 32 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
cellular response to ammonium ion GO:0071242 17 0.010
regulation of immune system process GO:0002682 123 0.010
adult locomotory behavior GO:0008344 4 0.010
formation of primary germ layer GO:0001704 1 0.010
regulation of dopamine secretion GO:0014059 15 0.010
dopamine transport GO:0015872 18 0.010
sequestering of metal ion GO:0051238 9 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
positive regulation of synaptic vesicle recycling GO:1903423 1 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.010

Itpka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.019
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
central nervous system disease DOID:331 0 0.013
inherited metabolic disorder DOID:655 0 0.013