Rattus norvegicus

0 known processes

Itsn1

intersectin 1 (SH3 domain protein)

(Aliases: Itsn)

Itsn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component assembly GO:0022607 360 0.100
Fly
anatomical structure morphogenesis GO:0009653 298 0.098
vesicle mediated transport GO:0016192 181 0.091
Yeast Fly
positive regulation of cell communication GO:0010647 271 0.087
Mouse
macromolecular complex subunit organization GO:0043933 339 0.078
cellular component biogenesis GO:0044085 368 0.072
Fly
cellular response to endogenous stimulus GO:0071495 377 0.062
salivary gland morphogenesis GO:0007435 1 0.062
regulation of molecular function GO:0065009 398 0.060
Mouse Fly
tissue development GO:0009888 252 0.060
protein complex assembly GO:0006461 263 0.056
reproductive process GO:0022414 372 0.055
transcription dna templated GO:0006351 377 0.053
multicellular organism reproduction GO:0032504 233 0.053
regulation of neuron differentiation GO:0045664 208 0.052
positive regulation of signaling GO:0023056 270 0.052
Mouse
protein complex subunit organization GO:0071822 302 0.051
carbohydrate derivative metabolic process GO:1901135 346 0.049
glycosyl compound metabolic process GO:1901657 182 0.049
intracellular signal transduction GO:0035556 314 0.048
Mouse
regulation of neurogenesis GO:0050767 247 0.048
Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.048
regulation of cellular component organization GO:0051128 368 0.047
regulation of protein modification process GO:0031399 194 0.047
Fly
membrane organization GO:0061024 94 0.046
multicellular organismal reproductive process GO:0048609 233 0.046
nucleic acid templated transcription GO:0097659 379 0.046
regulation of rna metabolic process GO:0051252 391 0.044
single organism reproductive process GO:0044702 297 0.043
protein phosphorylation GO:0006468 345 0.043
Fly
regulation of catalytic activity GO:0050790 304 0.043
Mouse Fly
regulation of cellular ketone metabolic process GO:0010565 27 0.043
nucleoside metabolic process GO:0009116 179 0.042
cellular response to stress GO:0033554 269 0.042
Yeast
regulation of multicellular organismal development GO:2000026 376 0.041
Fly
protein complex biogenesis GO:0070271 263 0.041
aromatic compound catabolic process GO:0019439 168 0.041
response to nutrient levels GO:0031667 370 0.041
rna biosynthetic process GO:0032774 380 0.040
oxoacid metabolic process GO:0043436 290 0.040
regulation of nervous system development GO:0051960 264 0.039
Fly
head development GO:0060322 247 0.039
single organism organelle organization GO:1902589 180 0.039
cell cycle GO:0007049 101 0.039
Yeast
rna metabolic process GO:0016070 406 0.038
regulation of cell differentiation GO:0045595 320 0.038
Fly
cell projection organization GO:0030030 302 0.037
regulation of signal transduction GO:0009966 318 0.037
Mouse Fly
salivary gland development GO:0007431 3 0.036
positive regulation of response to stimulus GO:0048584 285 0.036
Mouse
gland development GO:0048732 155 0.036
neuron differentiation GO:0030182 368 0.036
cellular ketone metabolic process GO:0042180 51 0.035
positive regulation of biosynthetic process GO:0009891 319 0.035
cellular amine metabolic process GO:0044106 38 0.035
organic acid metabolic process GO:0006082 292 0.035
developmental process involved in reproduction GO:0003006 159 0.035
regulation of apoptotic process GO:0042981 335 0.035
Mouse
localization of cell GO:0051674 202 0.034
secretion GO:0046903 307 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
Fly
macromolecular complex assembly GO:0065003 273 0.034
multi organism reproductive process GO:0044703 262 0.034
organic cyclic compound catabolic process GO:1901361 175 0.033
glycosyl compound catabolic process GO:1901658 126 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
Fly
central nervous system development GO:0007417 311 0.033
purine nucleoside metabolic process GO:0042278 169 0.032
positive regulation of molecular function GO:0044093 230 0.032
Mouse Fly
protein localization GO:0008104 191 0.032
Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
homeostatic process GO:0042592 331 0.031
ribonucleotide metabolic process GO:0009259 231 0.031
protein oligomerization GO:0051259 191 0.031
regulation of programmed cell death GO:0043067 341 0.031
Mouse
nucleoside catabolic process GO:0009164 126 0.031
apoptotic process GO:0006915 381 0.031
Mouse
organic substance catabolic process GO:1901575 316 0.031
amine metabolic process GO:0009308 38 0.031
reproductive structure development GO:0048608 128 0.031
cell cell signaling GO:0007267 335 0.030
Fly
negative regulation of multicellular organismal process GO:0051241 203 0.030
cellular component morphogenesis GO:0032989 155 0.030
response to oxidative stress GO:0006979 186 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
b cell differentiation GO:0030183 2 0.029
positive regulation of developmental process GO:0051094 283 0.029
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
mesoderm development GO:0007498 2 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
purine containing compound catabolic process GO:0072523 138 0.028
organelle organization GO:0006996 266 0.028
cytoskeleton organization GO:0007010 111 0.028
positive regulation of nucleic acid templated transcription GO:1903508 197 0.028
regulation of protein metabolic process GO:0051246 289 0.028
Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
Mouse Fly
cellular response to oxygen containing compound GO:1901701 386 0.027
response to other organism GO:0051707 220 0.027
regulation of cell projection organization GO:0031344 175 0.027
response to acid chemical GO:0001101 222 0.027
positive regulation of transcription dna templated GO:0045893 197 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.027
brain development GO:0007420 247 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
ribonucleoside triphosphate catabolic process GO:0009203 122 0.027
response to growth factor GO:0070848 189 0.027
regulation of transcription dna templated GO:0006355 374 0.026
heterocycle catabolic process GO:0046700 167 0.026
nucleoside triphosphate metabolic process GO:0009141 144 0.026
positive regulation of gene expression GO:0010628 244 0.026
regulation of cell development GO:0060284 263 0.026
Fly
regulation of phosphorus metabolic process GO:0051174 349 0.026
Mouse Fly
establishment of protein localization GO:0045184 141 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
catabolic process GO:0009056 351 0.025
epithelium development GO:0060429 96 0.025
ribonucleotide catabolic process GO:0009261 136 0.025
peptidyl amino acid modification GO:0018193 126 0.025
neurological system process GO:0050877 219 0.025
cellular catabolic process GO:0044248 295 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
transmembrane transport GO:0055085 412 0.024
negative regulation of metabolic process GO:0009892 331 0.023
regulation of transferase activity GO:0051338 123 0.023
Fly
cellular response to hormone stimulus GO:0032870 247 0.023
reproductive system development GO:0061458 128 0.023
regulation of phosphorylation GO:0042325 248 0.023
Mouse Fly
gamete generation GO:0007276 124 0.023
purine nucleotide catabolic process GO:0006195 136 0.023
response to extracellular stimulus GO:0009991 380 0.023
gastrulation GO:0007369 2 0.023
organophosphate metabolic process GO:0019637 370 0.023
single organism biosynthetic process GO:0044711 342 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
cellular component movement GO:0006928 248 0.022
programmed cell death GO:0012501 392 0.022
Mouse
positive regulation of catalytic activity GO:0043085 184 0.022
Mouse Fly
cellular response to organic cyclic compound GO:0071407 202 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
sexual reproduction GO:0019953 148 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
neuron projection development GO:0031175 273 0.022
regulation of cell proliferation GO:0042127 359 0.022
Fly
response to decreased oxygen levels GO:0036293 237 0.022
regulation of intracellular signal transduction GO:1902531 218 0.021
Mouse
purine containing compound metabolic process GO:0072521 253 0.021
cell morphogenesis involved in differentiation GO:0000904 119 0.021
nucleoside phosphate catabolic process GO:1901292 140 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
metal ion transport GO:0030001 289 0.021
positive regulation of cell development GO:0010720 176 0.021
Fly
nucleobase containing compound catabolic process GO:0034655 152 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.021
reproduction GO:0000003 245 0.021
actin filament based process GO:0030029 86 0.021
macromolecule localization GO:0033036 252 0.021
Fly
protein transport GO:0015031 132 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
Fly
regulation of cellular protein metabolic process GO:0032268 267 0.020
Fly
organonitrogen compound catabolic process GO:1901565 179 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
cellular macromolecule localization GO:0070727 122 0.020
cell morphogenesis GO:0000902 142 0.020
response to peptide hormone GO:0043434 278 0.020
growth GO:0040007 165 0.020
Fly
nucleotide catabolic process GO:0009166 139 0.020
cell migration GO:0016477 197 0.020
single organism intracellular transport GO:1902582 166 0.020
response to peptide GO:1901652 292 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
nucleotide metabolic process GO:0009117 279 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
Mouse
regulation of cell motility GO:2000145 131 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
Fly
oxidation reduction process GO:0055114 304 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.019
response to nutrient GO:0007584 248 0.019
cell motility GO:0048870 202 0.019
hair cell differentiation GO:0035315 2 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
response to cytokine GO:0034097 215 0.018
rhythmic process GO:0048511 156 0.018
negative regulation of cell death GO:0060548 229 0.018
Mouse
response to external biotic stimulus GO:0043207 221 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.018
Fly
cell projection morphogenesis GO:0048858 123 0.018
response to biotic stimulus GO:0009607 226 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
Mouse
response to estrogen GO:0043627 232 0.018
ion transmembrane transport GO:0034220 365 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
response to bacterium GO:0009617 200 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
response to reactive oxygen species GO:0000302 120 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
Fly
synaptic vesicle endocytosis GO:0048488 4 0.018
Fly
positive regulation of phosphorylation GO:0042327 177 0.017
Mouse Fly
behavior GO:0007610 205 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
response to oxygen levels GO:0070482 265 0.017
defense response GO:0006952 194 0.017
single organism catabolic process GO:0044712 283 0.017
regulation of neuron death GO:1901214 115 0.017
Mouse
positive regulation of cell death GO:0010942 184 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
mechanoreceptor differentiation GO:0042490 2 0.017
response to hypoxia GO:0001666 231 0.017
negative regulation of molecular function GO:0044092 133 0.017
hematopoietic progenitor cell differentiation GO:0002244 2 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
secretion by cell GO:0032940 248 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
Fly
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
spindle organization GO:0007051 2 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
Mouse Fly
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
reactive oxygen species metabolic process GO:0072593 37 0.016
protein homooligomerization GO:0051260 91 0.016
cellular response to lipid GO:0071396 201 0.016
adult locomotory behavior GO:0008344 4 0.016
axis specification GO:0009798 4 0.016
regulation of notch signaling pathway GO:0008593 3 0.016
Fly
regulation of cell morphogenesis GO:0022604 77 0.016
intracellular transport GO:0046907 185 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
regulation of cellular localization GO:0060341 263 0.016
regulation of neuron projection development GO:0010975 161 0.016
urogenital system development GO:0001655 78 0.015
organ morphogenesis GO:0009887 75 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
heart morphogenesis GO:0003007 3 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
response to estradiol GO:0032355 164 0.015
response to inorganic substance GO:0010035 377 0.015
response to ionizing radiation GO:0010212 59 0.015
response to radiation GO:0009314 137 0.015
locomotion GO:0040011 237 0.015
aging GO:0007568 241 0.015
cation transport GO:0006812 382 0.015
regulation of growth GO:0040008 105 0.015
neuron projection morphogenesis GO:0048812 122 0.014
sensory organ development GO:0007423 74 0.014
liver development GO:0001889 90 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
cellular component maintenance GO:0043954 4 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
ras protein signal transduction GO:0007265 29 0.014
proteolysis GO:0006508 175 0.014
cell part morphogenesis GO:0032990 123 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
organophosphate catabolic process GO:0046434 148 0.014
digestive system development GO:0055123 41 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
synaptic transmission GO:0007268 235 0.014
Fly
synapse assembly GO:0007416 29 0.013
Fly
negative regulation of gene expression GO:0010629 199 0.013
inner ear receptor cell differentiation GO:0060113 2 0.013
response to glucocorticoid GO:0051384 223 0.013
cellular lipid metabolic process GO:0044255 208 0.013
single organism membrane organization GO:0044802 74 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
cell junction maintenance GO:0034331 1 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
chromosome segregation GO:0007059 2 0.013
gliogenesis GO:0042063 93 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
intracellular protein transport GO:0006886 79 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
endomembrane system organization GO:0010256 48 0.013
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
cellular response to external stimulus GO:0071496 118 0.013
embryonic pattern specification GO:0009880 1 0.013
positive regulation of protein modification process GO:0031401 142 0.013
Fly
forebrain development GO:0030900 98 0.013
ribonucleoside monophosphate metabolic process GO:0009161 88 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
regulation of cell cycle GO:0051726 73 0.013
Yeast
mitotic spindle organization GO:0007052 2 0.013
sex differentiation GO:0007548 113 0.013
cellular chemical homeostasis GO:0055082 247 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
Mouse Fly
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
organelle localization GO:0051640 55 0.012
Fly
response to metal ion GO:0010038 253 0.012
multicellular organism growth GO:0035264 1 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
chemical homeostasis GO:0048878 292 0.012
negative regulation of cell development GO:0010721 82 0.012
spermatogenesis GO:0007283 99 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
regulation of secretion by cell GO:1903530 208 0.012
cellular response to oxidative stress GO:0034599 76 0.012
cytoskeleton dependent cytokinesis GO:0061640 2 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
olfactory behavior GO:0042048 2 0.012
tube development GO:0035295 89 0.012
positive regulation of signal transduction GO:0009967 175 0.012
Mouse
single organism cellular localization GO:1902580 102 0.012
ion homeostasis GO:0050801 212 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
neuron death GO:0070997 127 0.012
Mouse
actin cytoskeleton organization GO:0030036 73 0.012
nitrogen compound transport GO:0071705 229 0.012
negative regulation of developmental process GO:0051093 125 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
regeneration GO:0031099 163 0.012
regulation of system process GO:0044057 208 0.012
regulation of dendrite development GO:0050773 59 0.012
positive regulation of transport GO:0051050 245 0.012
cytoplasmic transport GO:0016482 115 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
Fly
negative regulation of catalytic activity GO:0043086 103 0.011
formation of primary germ layer GO:0001704 1 0.011
organ formation GO:0048645 3 0.011
sensory perception GO:0007600 101 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
cellular protein localization GO:0034613 122 0.011
auditory receptor cell differentiation GO:0042491 2 0.011
immune response GO:0006955 104 0.011
negative regulation of transport GO:0051051 136 0.011
response to vitamin GO:0033273 131 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
eye morphogenesis GO:0048592 4 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
chemosensory behavior GO:0007635 2 0.011
biological adhesion GO:0022610 110 0.011
motor neuron axon guidance GO:0008045 1 0.011
endocytosis GO:0006897 84 0.011
Yeast Fly
response to carbohydrate GO:0009743 183 0.011
cell cycle checkpoint GO:0000075 2 0.011
hormone transport GO:0009914 121 0.011
multicellular organismal signaling GO:0035637 44 0.011
regulation of cell migration GO:0030334 128 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
Fly
response to corticosteroid GO:0031960 235 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
dna metabolic process GO:0006259 96 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
lipid metabolic process GO:0006629 283 0.011
circulatory system process GO:0003013 183 0.011
cation transmembrane transport GO:0098655 263 0.011
organ regeneration GO:0031100 101 0.011
gonad development GO:0008406 104 0.011
hepaticobiliary system development GO:0061008 90 0.011
dephosphorylation GO:0016311 98 0.011
cellular homeostasis GO:0019725 252 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
regulation of body fluid levels GO:0050878 90 0.010
neuron development GO:0048666 286 0.010
regulation of cellular component movement GO:0051270 150 0.010
regulation of organelle organization GO:0033043 80 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
positive regulation of nervous system development GO:0051962 178 0.010
Fly
cell cycle process GO:0022402 57 0.010
Yeast
regulation of immune system process GO:0002682 123 0.010

Itsn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.019
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
nervous system disease DOID:863 0 0.011