Rattus norvegicus

40 known processes

Jag2

jagged 2

Jag2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.212
positive regulation of multicellular organismal process GO:0051240 387 0.205
Rat
macromolecular complex assembly GO:0065003 273 0.159
protein complex assembly GO:0006461 263 0.141
rna metabolic process GO:0016070 406 0.127
cell projection organization GO:0030030 302 0.127
transcription dna templated GO:0006351 377 0.123
rna biosynthetic process GO:0032774 380 0.114
protein complex biogenesis GO:0070271 263 0.113
regulation of cellular component organization GO:0051128 368 0.099
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.098
cellular component assembly GO:0022607 360 0.093
programmed cell death GO:0012501 392 0.089
Mouse
neuronal action potential GO:0019228 35 0.081
nucleic acid templated transcription GO:0097659 379 0.081
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.078
action potential GO:0001508 54 0.077
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.074
response to peptide hormone GO:0043434 278 0.074
positive regulation of rna metabolic process GO:0051254 203 0.074
macromolecule localization GO:0033036 252 0.074
response to peptide GO:1901652 292 0.071
protein phosphorylation GO:0006468 345 0.070
regulation of apoptotic signaling pathway GO:2001233 13 0.068
positive regulation of cellular protein metabolic process GO:0032270 167 0.067
positive regulation of rna biosynthetic process GO:1902680 197 0.066
regulation of transcription dna templated GO:0006355 374 0.064
sensory organ development GO:0007423 74 0.063
Mouse Rat Fly
protein complex subunit organization GO:0071822 302 0.061
mesoderm development GO:0007498 2 0.060
lymphoid progenitor cell differentiation GO:0002320 2 0.060
reproduction GO:0000003 245 0.058
cellular amine metabolic process GO:0044106 38 0.057
s shaped body morphogenesis GO:0072050 2 0.055
positive regulation of transcription dna templated GO:0045893 197 0.054
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.053
regulation of phosphorus metabolic process GO:0051174 349 0.053
regulation of membrane potential GO:0042391 110 0.053
apoptotic process GO:0006915 381 0.052
Mouse
protein localization GO:0008104 191 0.051
locomotion GO:0040011 237 0.050
response to nutrient levels GO:0031667 370 0.050
macromolecular complex subunit organization GO:0043933 339 0.049
transcription from rna polymerase ii promoter GO:0006366 252 0.049
neurological system process GO:0050877 219 0.049
regulation of locomotion GO:0040012 148 0.048
cellular ketone metabolic process GO:0042180 51 0.047
cellular component biogenesis GO:0044085 368 0.046
multicellular organism growth GO:0035264 1 0.046
regulation of nervous system development GO:0051960 264 0.046
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.045
regulation of neurogenesis GO:0050767 247 0.044
Rat
neuron differentiation GO:0030182 368 0.044
Zebrafish Mouse Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.043
regulation of protein phosphorylation GO:0001932 183 0.041
regulation of rna biosynthetic process GO:2001141 381 0.041
positive regulation of nervous system development GO:0051962 178 0.041
Rat
gastrulation GO:0007369 2 0.040
regulation of cellular component biogenesis GO:0044087 86 0.040
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.039
cellular response to insulin stimulus GO:0032869 81 0.039
neuron development GO:0048666 286 0.038
negative regulation of cell communication GO:0010648 158 0.037
Rat Fly
reproductive system development GO:0061458 128 0.037
gliogenesis GO:0042063 93 0.037
Rat Fly
cell morphogenesis involved in differentiation GO:0000904 119 0.037
positive regulation of protein metabolic process GO:0051247 178 0.036
response to monosaccharide GO:0034284 159 0.036
multicellular organismal reproductive process GO:0048609 233 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
regulation of system process GO:0044057 208 0.035
metanephric comma shaped body morphogenesis GO:0072278 2 0.035
response to external biotic stimulus GO:0043207 221 0.034
response to extracellular stimulus GO:0009991 380 0.034
tissue development GO:0009888 252 0.034
Mouse Rat
anatomical structure morphogenesis GO:0009653 298 0.033
Mouse Fly
regulation of protein modification process GO:0031399 194 0.033
regulation of multicellular organismal development GO:2000026 376 0.032
Rat
secretion by cell GO:0032940 248 0.032
cell projection morphogenesis GO:0048858 123 0.032
protein heterooligomerization GO:0051291 89 0.032
negative regulation of biosynthetic process GO:0009890 168 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
dna metabolic process GO:0006259 96 0.031
mesoderm formation GO:0001707 1 0.031
neuron projection morphogenesis GO:0048812 122 0.031
membrane repolarization GO:0086009 1 0.031
organelle organization GO:0006996 266 0.030
amine metabolic process GO:0009308 38 0.029
cell part morphogenesis GO:0032990 123 0.029
sensory perception GO:0007600 101 0.028
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
positive regulation of gene expression GO:0010628 244 0.028
regulation of cell projection organization GO:0031344 175 0.027
response to oxidative stress GO:0006979 186 0.027
intracellular transport GO:0046907 185 0.027
head development GO:0060322 247 0.027
cell morphogenesis GO:0000902 142 0.027
cation transport GO:0006812 382 0.027
peptidyl amino acid modification GO:0018193 126 0.027
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 1 0.027
organ regeneration GO:0031100 101 0.026
Rat
insulin like growth factor receptor signaling pathway GO:0048009 3 0.025
cellular component morphogenesis GO:0032989 155 0.025
negative regulation of metabolic process GO:0009892 331 0.025
cellular protein localization GO:0034613 122 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
hematopoietic progenitor cell differentiation GO:0002244 2 0.025
cellular response to external stimulus GO:0071496 118 0.024
single organism reproductive process GO:0044702 297 0.024
positive regulation of transport GO:0051050 245 0.024
cell motility GO:0048870 202 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
protein oligomerization GO:0051259 191 0.024
embryo development GO:0009790 49 0.024
Mouse
transmission of nerve impulse GO:0019226 42 0.024
response to hexose GO:0009746 144 0.024
response to camp GO:0051591 91 0.024
rhythmic process GO:0048511 156 0.023
heart morphogenesis GO:0003007 3 0.023
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 2 0.023
organic substance catabolic process GO:1901575 316 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
neuron projection development GO:0031175 273 0.023
inorganic cation transmembrane transport GO:0098662 202 0.023
regulation of cell differentiation GO:0045595 320 0.022
Rat Fly
positive regulation of cellular component organization GO:0051130 200 0.022
cellular response to steroid hormone stimulus GO:0071383 93 0.022
hormone metabolic process GO:0042445 69 0.022
localization of cell GO:0051674 202 0.021
homeostatic process GO:0042592 331 0.021
positive regulation of developmental process GO:0051094 283 0.021
Rat
response to glucose GO:0009749 136 0.021
regulation of ion transport GO:0043269 245 0.021
positive regulation of protein modification process GO:0031401 142 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
secretion GO:0046903 307 0.020
positive regulation of cell communication GO:0010647 271 0.020
positive regulation of cell motility GO:2000147 97 0.020
regulation of bmp signaling pathway GO:0030510 2 0.019
regulation of signal transduction GO:0009966 318 0.019
Rat Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.019
sex differentiation GO:0007548 113 0.019
bmp signaling pathway GO:0030509 4 0.019
positive regulation of signal transduction GO:0009967 175 0.019
hair follicle development GO:0001942 2 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
multicellular organism reproduction GO:0032504 233 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
metal ion transport GO:0030001 289 0.018
organ morphogenesis GO:0009887 75 0.018
Mouse Fly
retina morphogenesis in camera type eye GO:0060042 1 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
positive regulation of cellular component movement GO:0051272 102 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
biological adhesion GO:0022610 110 0.018
Mouse
eye morphogenesis GO:0048592 4 0.018
Fly
cardiovascular system development GO:0072358 134 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
multicellular organismal signaling GO:0035637 44 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
single organism biosynthetic process GO:0044711 342 0.017
negative regulation of cell death GO:0060548 229 0.017
protein autophosphorylation GO:0046777 66 0.017
positive regulation of molecular function GO:0044093 230 0.017
sexual reproduction GO:0019953 148 0.017
regulation of neuron projection development GO:0010975 161 0.017
response to carbohydrate GO:0009743 183 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
formation of primary germ layer GO:0001704 1 0.017
regulation of catabolic process GO:0009894 113 0.017
regulation of protein metabolic process GO:0051246 289 0.016
regulation of molecular function GO:0065009 398 0.016
regulation of neuron differentiation GO:0045664 208 0.016
response to oxygen levels GO:0070482 265 0.016
regulation of apoptotic process GO:0042981 335 0.016
positive regulation of catabolic process GO:0009896 78 0.016
negative regulation of signaling GO:0023057 157 0.016
Rat Fly
lateral ventricle development GO:0021670 1 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
molting cycle process GO:0022404 2 0.016
regulation of anatomical structure size GO:0090066 135 0.015
membrane organization GO:0061024 94 0.015
mesoderm morphogenesis GO:0048332 1 0.015
negative regulation of heart growth GO:0061117 3 0.015
epithelium development GO:0060429 96 0.015
Mouse Rat
response to glucocorticoid GO:0051384 223 0.015
single organism organelle organization GO:1902589 180 0.015
peptidyl tyrosine modification GO:0018212 72 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
response to estradiol GO:0032355 164 0.015
single organism intracellular transport GO:1902582 166 0.015
ear development GO:0043583 21 0.015
Mouse Rat
dendrite development GO:0016358 72 0.015
negative regulation of transport GO:0051051 136 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
dendrite morphogenesis GO:0048813 43 0.015
regulation of mesenchymal cell proliferation GO:0010464 4 0.015
skin morphogenesis GO:0043589 2 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
regulation of dna metabolic process GO:0051052 60 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
immune system process GO:0002376 204 0.014
Human Mouse Fly
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.014
hair cycle process GO:0022405 2 0.014
axon development GO:0061564 96 0.014
peptidyl tyrosine phosphorylation GO:0018108 72 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
regulation of organelle organization GO:0033043 80 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
Rat
cellular response to oxidative stress GO:0034599 76 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
positive regulation of growth GO:0045927 55 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
Rat
intracellular signal transduction GO:0035556 314 0.014
single organism catabolic process GO:0044712 283 0.014
aging GO:0007568 241 0.014
cell migration GO:0016477 197 0.014
negative regulation of cell development GO:0010721 82 0.014
Rat
eye development GO:0001654 50 0.014
Fly
behavior GO:0007610 205 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
regulation of stem cell differentiation GO:2000736 2 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
cation transmembrane transport GO:0098655 263 0.013
muscle structure development GO:0061061 87 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
regulation of cell proliferation GO:0042127 359 0.013
Human Rat
cell adhesion GO:0007155 110 0.013
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
gonad development GO:0008406 104 0.013
protein transport GO:0015031 132 0.013
single organism cell adhesion GO:0098602 46 0.013
camera type eye morphogenesis GO:0048593 2 0.013
hexose metabolic process GO:0019318 58 0.013
cellular modified amino acid metabolic process GO:0006575 61 0.013
cellular catabolic process GO:0044248 295 0.013
triglyceride homeostasis GO:0070328 2 0.013
gamete generation GO:0007276 124 0.013
cellular macromolecule localization GO:0070727 122 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
oxoacid metabolic process GO:0043436 290 0.013
development of primary sexual characteristics GO:0045137 107 0.013
activation of protein kinase b activity GO:0032148 3 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
Rat
regulation of developmental growth GO:0048638 45 0.012
catabolic process GO:0009056 351 0.012
activation of protein kinase activity GO:0032147 47 0.012
ovulation cycle process GO:0022602 50 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.012
response to nutrient GO:0007584 248 0.012
axonogenesis GO:0007409 71 0.012
response to estrogen GO:0043627 232 0.012
regulation of hormone levels GO:0010817 187 0.012
positive regulation of cell development GO:0010720 176 0.012
Rat
carboxylic acid metabolic process GO:0019752 289 0.012
axon ensheathment GO:0008366 40 0.012
regulation of programmed cell death GO:0043067 341 0.012
regulation of catalytic activity GO:0050790 304 0.012
follicle stimulating hormone signaling pathway GO:0042699 5 0.012
molting cycle GO:0042303 3 0.012
palate development GO:0060021 2 0.012
Mouse
gland development GO:0048732 155 0.012
Zebrafish Fly
hair cycle GO:0042633 3 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
organophosphate metabolic process GO:0019637 370 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
cellular response to peptide GO:1901653 133 0.012
heterocycle catabolic process GO:0046700 167 0.012
regulation of dendrite development GO:0050773 59 0.012
cell growth GO:0016049 104 0.012
urogenital system development GO:0001655 78 0.012
Zebrafish
developmental process involved in reproduction GO:0003006 159 0.011
negative regulation of signal transduction GO:0009968 83 0.011
Rat Fly
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.011
pro t cell differentiation GO:0002572 1 0.011
cytoplasmic transport GO:0016482 115 0.011
skin development GO:0043588 17 0.011
Mouse Rat
cellular response to abiotic stimulus GO:0071214 85 0.011
positive regulation of signaling GO:0023056 270 0.011
salivary gland development GO:0007431 3 0.011
Fly
cellular response to stress GO:0033554 269 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
axon guidance GO:0007411 24 0.011
positive regulation of transferase activity GO:0051347 81 0.011
ensheathment of neurons GO:0007272 40 0.011
intracellular protein transport GO:0006886 79 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
embryonic pattern specification GO:0009880 1 0.011
circadian regulation of gene expression GO:0032922 3 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
developmental growth GO:0048589 100 0.011
negative regulation of organ growth GO:0046621 3 0.011
male gamete generation GO:0048232 99 0.011
metanephric mesenchymal cell migration GO:0035789 2 0.011
establishment of protein localization to membrane GO:0090150 16 0.011
apoptotic signaling pathway GO:0097190 27 0.011
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.010
regulation of growth GO:0040008 105 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
circadian rhythm GO:0007623 88 0.010
regulation of fat cell differentiation GO:0045598 3 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
cellular response to carbohydrate stimulus GO:0071322 72 0.010
cell substrate adhesion GO:0031589 29 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
regulation of gtp catabolic process GO:0033124 58 0.010
spinal cord development GO:0021510 27 0.010
Zebrafish
monovalent inorganic cation transport GO:0015672 172 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
response to other organism GO:0051707 220 0.010
regulation of cytoskeleton organization GO:0051493 49 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
nucleoside metabolic process GO:0009116 179 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
Rat Fly
inner ear development GO:0048839 21 0.010
Mouse Rat

Jag2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.013
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013