Rattus norvegicus

21 known processes

Jak1

Janus kinase 1

Jak1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component organization GO:0051128 368 0.913
protein autophosphorylation GO:0046777 66 0.791
intracellular signal transduction GO:0035556 314 0.767
response to wounding GO:0009611 254 0.762
positive regulation of response to stimulus GO:0048584 285 0.712
positive regulation of cell migration GO:0030335 96 0.703
regulation of cell differentiation GO:0045595 320 0.671
regulation of cellular localization GO:0060341 263 0.670
cell morphogenesis GO:0000902 142 0.644
regulation of intracellular signal transduction GO:1902531 218 0.624
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.607
regulation of phosphorus metabolic process GO:0051174 349 0.600
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.598
protein complex assembly GO:0006461 263 0.581
regulation of neurogenesis GO:0050767 247 0.571
regulation of vesicle mediated transport GO:0060627 81 0.557
enzyme linked receptor protein signaling pathway GO:0007167 116 0.548
neuron differentiation GO:0030182 368 0.544
cellular response to stress GO:0033554 269 0.539
regulation of cell development GO:0060284 263 0.538
cellular component biogenesis GO:0044085 368 0.538
positive regulation of cell differentiation GO:0045597 217 0.529
regulation of mapk cascade GO:0043408 116 0.529
signal transduction by phosphorylation GO:0023014 144 0.529
regulation of multicellular organismal development GO:2000026 376 0.523
positive regulation of developmental process GO:0051094 283 0.517
protein complex biogenesis GO:0070271 263 0.513
neuron projection development GO:0031175 273 0.509
transcription dna templated GO:0006351 377 0.507
positive regulation of transcription dna templated GO:0045893 197 0.502
regulation of cellular component movement GO:0051270 150 0.500
regulation of response to stress GO:0080134 126 0.500
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.499
positive regulation of locomotion GO:0040017 102 0.497
immune response GO:0006955 104 0.494
positive regulation of nucleic acid templated transcription GO:1903508 197 0.491
positive regulation of cell motility GO:2000147 97 0.488
regulation of phosphate metabolic process GO:0019220 349 0.485
positive regulation of transport GO:0051050 245 0.478
wound healing GO:0042060 122 0.467
positive regulation of cellular component organization GO:0051130 200 0.462
positive regulation of cell development GO:0010720 176 0.456
cellular ketone metabolic process GO:0042180 51 0.454
positive regulation of hydrolase activity GO:0051345 86 0.450
locomotion GO:0040011 237 0.448
vesicle mediated transport GO:0016192 181 0.444
cellular component assembly GO:0022607 360 0.438
positive regulation of multicellular organismal process GO:0051240 387 0.436
cell projection organization GO:0030030 302 0.433
regulation of anatomical structure morphogenesis GO:0022603 141 0.433
positive regulation of cellular component biogenesis GO:0044089 55 0.430
rna biosynthetic process GO:0032774 380 0.427
regulation of cellular protein metabolic process GO:0032268 267 0.420
response to hypoxia GO:0001666 231 0.411
protein complex subunit organization GO:0071822 302 0.404
regulation of signal transduction GO:0009966 318 0.401
positive regulation of signaling GO:0023056 270 0.395
regulation of nervous system development GO:0051960 264 0.393
response to cytokine GO:0034097 215 0.381
neuron projection morphogenesis GO:0048812 122 0.380
positive regulation of cellular biosynthetic process GO:0031328 295 0.376
response to radiation GO:0009314 137 0.369
regulation of neuron differentiation GO:0045664 208 0.368
myeloid cell differentiation GO:0030099 22 0.367
positive regulation of rna biosynthetic process GO:1902680 197 0.363
regulation of protein metabolic process GO:0051246 289 0.352
macromolecular complex assembly GO:0065003 273 0.351
apoptotic process GO:0006915 381 0.349
regulation of phosphorylation GO:0042325 248 0.347
macromolecule localization GO:0033036 252 0.342
response to growth factor GO:0070848 189 0.341
homeostatic process GO:0042592 331 0.340
intracellular transport GO:0046907 185 0.338
neuron development GO:0048666 286 0.336
positive regulation of biosynthetic process GO:0009891 319 0.336
regulation of neuron projection development GO:0010975 161 0.333
nucleic acid templated transcription GO:0097659 379 0.328
macromolecular complex subunit organization GO:0043933 339 0.320
tube development GO:0035295 89 0.320
regulation of protein modification process GO:0031399 194 0.317
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.315
response to oxidative stress GO:0006979 186 0.314
positive regulation of neurogenesis GO:0050769 165 0.313
regulation of cell morphogenesis GO:0022604 77 0.311
cellular metal ion homeostasis GO:0006875 172 0.310
aging GO:0007568 241 0.310
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.308
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.304
protein transport GO:0015031 132 0.301
positive regulation of phosphate metabolic process GO:0045937 262 0.300
regulation of cell motility GO:2000145 131 0.297
protein maturation GO:0051604 68 0.294
blood vessel morphogenesis GO:0048514 58 0.293
regulation of transcription dna templated GO:0006355 374 0.292
carbohydrate derivative metabolic process GO:1901135 346 0.292
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.290
response to light stimulus GO:0009416 52 0.289
regulation of endocytosis GO:0030100 42 0.288
negative regulation of cell differentiation GO:0045596 99 0.288
anatomical structure morphogenesis GO:0009653 298 0.286
tissue development GO:0009888 252 0.286
regulation of response to external stimulus GO:0032101 106 0.285
t cell chemotaxis GO:0010818 2 0.281
positive regulation of protein transport GO:0051222 41 0.281
positive regulation of nervous system development GO:0051962 178 0.279
mapk cascade GO:0000165 140 0.278
endocytosis GO:0006897 84 0.278
regulation of molecular function GO:0065009 398 0.277
response to toxic substance GO:0009636 133 0.272
negative regulation of rna biosynthetic process GO:1902679 118 0.272
immune system process GO:0002376 204 0.270
regulation of immune system process GO:0002682 123 0.267
growth GO:0040007 165 0.266
regulation of hydrolase activity GO:0051336 143 0.265
cytokine production GO:0001816 61 0.258
regulation of protein complex assembly GO:0043254 33 0.252
regulation of cellular ketone metabolic process GO:0010565 27 0.251
positive regulation of cell communication GO:0010647 271 0.251
cellular response to growth factor stimulus GO:0071363 162 0.249
cellular component movement GO:0006928 248 0.248
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.247
regulation of ossification GO:0030278 32 0.244
positive regulation of protein metabolic process GO:0051247 178 0.242
negative regulation of cellular metabolic process GO:0031324 281 0.241
inflammatory response GO:0006954 150 0.241
regulation of nucleic acid templated transcription GO:1903506 380 0.240
regulation of cell migration GO:0030334 128 0.239
response to molecule of bacterial origin GO:0002237 194 0.237
positive regulation of gene expression GO:0010628 244 0.237
regulation of protein phosphorylation GO:0001932 183 0.236
negative regulation of macromolecule metabolic process GO:0010605 260 0.235
positive regulation of rna metabolic process GO:0051254 203 0.235
cell type specific apoptotic process GO:0097285 134 0.230
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.225
circulatory system development GO:0072359 134 0.225
carboxylic acid metabolic process GO:0019752 289 0.224
cell migration GO:0016477 197 0.223
regulation of rna biosynthetic process GO:2001141 381 0.222
negative regulation of metabolic process GO:0009892 331 0.222
cellular response to lipid GO:0071396 201 0.220
response to amino acid GO:0043200 75 0.219
positive regulation of intracellular signal transduction GO:1902533 138 0.219
proteolysis GO:0006508 175 0.216
positive regulation of nucleocytoplasmic transport GO:0046824 17 0.216
defense response GO:0006952 194 0.216
negative regulation of cell death GO:0060548 229 0.216
erythrocyte differentiation GO:0030218 1 0.214
single organism organelle organization GO:1902589 180 0.213
negative regulation of developmental process GO:0051093 125 0.210
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.209
central nervous system development GO:0007417 311 0.208
regulation of peptidase activity GO:0052547 55 0.199
ribonucleotide metabolic process GO:0009259 231 0.199
nucleoside phosphate metabolic process GO:0006753 283 0.198
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.197
cellular response to organic cyclic compound GO:0071407 202 0.196
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.195
regulation of cellular response to growth factor stimulus GO:0090287 15 0.194
secretion GO:0046903 307 0.193
programmed cell death GO:0012501 392 0.191
single organism intracellular transport GO:1902582 166 0.191
negative regulation of multicellular organismal process GO:0051241 203 0.190
cellular component morphogenesis GO:0032989 155 0.190
positive regulation of signal transduction GO:0009967 175 0.190
positive regulation of cellular protein metabolic process GO:0032270 167 0.189
response to reactive oxygen species GO:0000302 120 0.187
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.186
rna metabolic process GO:0016070 406 0.186
response to lipopolysaccharide GO:0032496 191 0.185
response to corticosteroid GO:0031960 235 0.184
protein phosphorylation GO:0006468 345 0.182
purine ribonucleotide metabolic process GO:0009150 227 0.182
regulation of blood circulation GO:1903522 110 0.182
regeneration GO:0031099 163 0.181
regulation of catalytic activity GO:0050790 304 0.179
single organism catabolic process GO:0044712 283 0.176
positive regulation of immune system process GO:0002684 90 0.175
ribonucleoside triphosphate metabolic process GO:0009199 141 0.172
purine containing compound metabolic process GO:0072521 253 0.172
cell motility GO:0048870 202 0.171
positive regulation of programmed cell death GO:0043068 157 0.170
response to bacterium GO:0009617 200 0.170
epithelium development GO:0060429 96 0.167
purine nucleotide metabolic process GO:0006163 229 0.166
regulation of cell projection organization GO:0031344 175 0.166
carbohydrate metabolic process GO:0005975 130 0.166
hemopoiesis GO:0030097 34 0.166
negative regulation of gene expression GO:0010629 199 0.165
positive regulation of molecular function GO:0044093 230 0.164
leukocyte activation GO:0045321 76 0.164
response to mechanical stimulus GO:0009612 134 0.162
response to glucocorticoid GO:0051384 223 0.162
regulation of cell proliferation GO:0042127 359 0.162
regulation of secretion GO:0051046 224 0.161
cell adhesion GO:0007155 110 0.159
regulation of wound healing GO:0061041 14 0.159
cellular response to oxygen containing compound GO:1901701 386 0.158
dendrite morphogenesis GO:0048813 43 0.158
regulation of cellular amino acid metabolic process GO:0006521 2 0.157
regulation of cytokine production GO:0001817 56 0.154
amine metabolic process GO:0009308 38 0.154
negative regulation of rna metabolic process GO:0051253 123 0.153
cellular response to endogenous stimulus GO:0071495 377 0.153
cellular response to molecule of bacterial origin GO:0071219 56 0.153
smad protein complex assembly GO:0007183 1 0.152
cellular response to abiotic stimulus GO:0071214 85 0.151
circulatory system process GO:0003013 183 0.150
regulation of cytoskeleton organization GO:0051493 49 0.149
transcription from rna polymerase ii promoter GO:0006366 252 0.149
regulation of cellular amine metabolic process GO:0033238 8 0.146
positive regulation of interleukin 1 beta production GO:0032731 6 0.145
stem cell maintenance GO:0019827 6 0.144
response to glucose GO:0009749 136 0.144
localization of cell GO:0051674 202 0.143
p38mapk cascade GO:0038066 1 0.143
response to oxygen levels GO:0070482 265 0.141
blood circulation GO:0008015 183 0.140
cytoskeleton organization GO:0007010 111 0.140
biological adhesion GO:0022610 110 0.140
behavior GO:0007610 205 0.138
organic acid metabolic process GO:0006082 292 0.137
hematopoietic or lymphoid organ development GO:0048534 36 0.136
cellular amino acid metabolic process GO:0006520 107 0.136
stress activated protein kinase signaling cascade GO:0031098 37 0.136
protein processing GO:0016485 68 0.134
cellular cation homeostasis GO:0030003 180 0.133
positive regulation of behavior GO:0048520 38 0.132
negative regulation of biosynthetic process GO:0009890 168 0.132
regulation of apoptotic process GO:0042981 335 0.132
cellular homeostasis GO:0019725 252 0.132
regulation of programmed cell death GO:0043067 341 0.132
embryonic appendage morphogenesis GO:0035113 4 0.132
vasculature development GO:0001944 70 0.131
positive regulation of intracellular protein transport GO:0090316 20 0.131
establishment of protein localization GO:0045184 141 0.131
regulation of organelle organization GO:0033043 80 0.130
erk1 and erk2 cascade GO:0070371 48 0.130
cellular calcium ion homeostasis GO:0006874 160 0.129
immune system development GO:0002520 41 0.129
positive regulation of catalytic activity GO:0043085 184 0.128
cellular macromolecule localization GO:0070727 122 0.127
positive regulation of secretion GO:0051047 140 0.127
organophosphate metabolic process GO:0019637 370 0.127
response to other organism GO:0051707 220 0.127
regulation of protein localization GO:0032880 81 0.125
cell projection morphogenesis GO:0048858 123 0.125
myeloid leukocyte differentiation GO:0002573 20 0.125
negative regulation of muscle cell apoptotic process GO:0010656 21 0.124
head development GO:0060322 247 0.123
apoptotic signaling pathway GO:0097190 27 0.123
negative regulation of cardiac muscle cell proliferation GO:0060044 2 0.121
regulation of locomotion GO:0040012 148 0.121
peptidyl tyrosine modification GO:0018212 72 0.121
dendrite development GO:0016358 72 0.121
cellular ion homeostasis GO:0006873 184 0.120
regulation of kinase activity GO:0043549 117 0.117
cellular response to oxidative stress GO:0034599 76 0.116
actin filament based process GO:0030029 86 0.116
metal ion homeostasis GO:0055065 186 0.115
cell part morphogenesis GO:0032990 123 0.115
cell morphogenesis involved in differentiation GO:0000904 119 0.114
negative regulation of signal transduction GO:0009968 83 0.113
negative regulation of apoptotic process GO:0043066 181 0.113
neuron apoptotic process GO:0051402 88 0.111
negative regulation of cellular biosynthetic process GO:0031327 161 0.111
positive regulation of protein modification process GO:0031401 142 0.111
response to extracellular stimulus GO:0009991 380 0.110
positive regulation of t cell migration GO:2000406 1 0.110
regulation of protein kinase activity GO:0045859 105 0.109
positive regulation of cytokine production GO:0001819 42 0.109
regulation of stress activated mapk cascade GO:0032872 23 0.109
negative regulation of cell communication GO:0010648 158 0.109
nucleoside phosphate catabolic process GO:1901292 140 0.108
regulation of protein transport GO:0051223 68 0.107
response to inorganic substance GO:0010035 377 0.107
cell cell signaling GO:0007267 335 0.107
cellular response to hormone stimulus GO:0032870 247 0.106
cellular amine metabolic process GO:0044106 38 0.106
t cell activation GO:0042110 29 0.105
autophagy GO:0006914 19 0.105
nucleoside catabolic process GO:0009164 126 0.105
positive regulation of cell death GO:0010942 184 0.105
response to decreased oxygen levels GO:0036293 237 0.104
striated muscle tissue development GO:0014706 58 0.104
response to carbohydrate GO:0009743 183 0.103
positive regulation of cell proliferation GO:0008284 249 0.103
positive regulation of phosphorus metabolic process GO:0010562 262 0.101
divalent inorganic cation homeostasis GO:0072507 165 0.101
regulation of nucleocytoplasmic transport GO:0046822 28 0.100
negative regulation of nucleic acid templated transcription GO:1903507 117 0.099
negative regulation of transcription dna templated GO:0045892 116 0.099
positive regulation of chemotaxis GO:0050921 23 0.098
positive regulation of cytoplasmic transport GO:1903651 32 0.098
activation of cysteine type endopeptidase activity GO:0097202 4 0.097
cellular catabolic process GO:0044248 295 0.097
cation homeostasis GO:0055080 195 0.097
cellular protein complex assembly GO:0043623 44 0.096
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.094
regulation of transferase activity GO:0051338 123 0.094
purine nucleoside metabolic process GO:0042278 169 0.094
sex differentiation GO:0007548 113 0.093
response to interleukin 13 GO:0035962 3 0.093
cellular response to biotic stimulus GO:0071216 59 0.092
regulation of erk1 and erk2 cascade GO:0070372 41 0.092
muscle cell proliferation GO:0033002 84 0.092
positive regulation of protein localization to nucleus GO:1900182 15 0.091
positive regulation of mapk cascade GO:0043410 92 0.091
positive regulation of cell projection organization GO:0031346 111 0.090
forebrain development GO:0030900 98 0.090
regulation of map kinase activity GO:0043405 53 0.090
catabolic process GO:0009056 351 0.089
nitrogen compound transport GO:0071705 229 0.089
actin filament based movement GO:0030048 16 0.089
positive regulation of neuron differentiation GO:0045666 126 0.088
mechanoreceptor differentiation GO:0042490 2 0.087
response to hexose GO:0009746 144 0.087
response to estrogen GO:0043627 232 0.086
development of primary sexual characteristics GO:0045137 107 0.086
organelle organization GO:0006996 266 0.086
ion homeostasis GO:0050801 212 0.086
negative regulation of peptidase activity GO:0010466 38 0.085
regulation of behavior GO:0050795 61 0.085
peptidyl tyrosine phosphorylation GO:0018108 72 0.085
positive regulation of jak stat cascade GO:0046427 19 0.083
synaptic growth at neuromuscular junction GO:0051124 1 0.083
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.082
regulation of secretion by cell GO:1903530 208 0.082
peptidyl amino acid modification GO:0018193 126 0.081
oxoacid metabolic process GO:0043436 290 0.080
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 3 0.080
multicellular organism growth GO:0035264 1 0.080
regulation of cell adhesion GO:0030155 52 0.079
ventricular cardiac muscle cell action potential GO:0086005 2 0.079
cellular response to lipopolysaccharide GO:0071222 55 0.079
ribonucleoside metabolic process GO:0009119 174 0.079
morphogenesis of an epithelium GO:0002009 20 0.078
regulation of proteolysis GO:0030162 66 0.078
positive regulation of cellular component movement GO:0051272 102 0.077
jnk cascade GO:0007254 28 0.077
regulation of endopeptidase activity GO:0052548 51 0.077
protein localization to organelle GO:0033365 57 0.076
small gtpase mediated signal transduction GO:0007264 36 0.075
positive regulation of epithelial cell migration GO:0010634 13 0.075
multicellular organismal reproductive process GO:0048609 233 0.075
vascular endothelial growth factor receptor signaling pathway GO:0048010 8 0.075
vascular process in circulatory system GO:0003018 96 0.075
microtubule based process GO:0007017 36 0.074
blood vessel development GO:0001568 69 0.073
cellular response to corticosteroid stimulus GO:0071384 69 0.073
cell junction organization GO:0034330 21 0.072
positive regulation of cellular amine metabolic process GO:0033240 3 0.072
regulation of system process GO:0044057 208 0.071
regulation of cellular component biogenesis GO:0044087 86 0.071
positive regulation of response to external stimulus GO:0032103 51 0.071
response to biotic stimulus GO:0009607 226 0.071
nucleotide metabolic process GO:0009117 279 0.070
purine containing compound catabolic process GO:0072523 138 0.070
actin cytoskeleton organization GO:0030036 73 0.070
positive regulation of apoptotic process GO:0043065 154 0.070
reproductive system development GO:0061458 128 0.069
purine nucleoside catabolic process GO:0006152 124 0.069
signal release GO:0023061 145 0.069
regulation of nucleotide metabolic process GO:0006140 117 0.069
cation transport GO:0006812 382 0.069
regulation of anatomical structure size GO:0090066 135 0.068
single organism behavior GO:0044708 130 0.068
chemical homeostasis GO:0048878 292 0.068
carbohydrate derivative catabolic process GO:1901136 147 0.068
developmental process involved in reproduction GO:0003006 159 0.067
ossification GO:0001503 70 0.067
cellular protein localization GO:0034613 122 0.067
cellular response to ketone GO:1901655 51 0.067
cellular chemical homeostasis GO:0055082 247 0.067
lipid metabolic process GO:0006629 283 0.066
regulation of lymphocyte migration GO:2000401 1 0.066
inner ear receptor cell differentiation GO:0060113 2 0.066
response to nutrient levels GO:0031667 370 0.066
digestive system development GO:0055123 41 0.065
response to ionizing radiation GO:0010212 59 0.065
metal ion transport GO:0030001 289 0.065
regulation of chromosome organization GO:0033044 9 0.065
hair cell differentiation GO:0035315 2 0.065
neurological system process GO:0050877 219 0.063
response to monosaccharide GO:0034284 159 0.063
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.063
multi organism reproductive process GO:0044703 262 0.063
calcium ion transport GO:0006816 131 0.063
regulation of ion transport GO:0043269 245 0.063
negative regulation of molecular function GO:0044092 133 0.063
cell cycle GO:0007049 101 0.063
regulation of cell cell adhesion GO:0022407 14 0.063
organic hydroxy compound metabolic process GO:1901615 115 0.062
organic substance catabolic process GO:1901575 316 0.062
glycosyl compound metabolic process GO:1901657 182 0.062
ribonucleoside triphosphate catabolic process GO:0009203 122 0.062
response to metal ion GO:0010038 253 0.061
actin mediated cell contraction GO:0070252 12 0.061
response to dexamethasone GO:0071548 49 0.060
brain development GO:0007420 247 0.060
single organism nuclear import GO:1902593 35 0.060
purine ribonucleotide catabolic process GO:0009154 136 0.059
regulation of immune response GO:0050776 55 0.059
innate immune response GO:0045087 35 0.059
negative regulation of growth GO:0045926 37 0.058
activation of protein kinase activity GO:0032147 47 0.058
embryonic limb morphogenesis GO:0030326 4 0.058
negative regulation of organ growth GO:0046621 3 0.058
ras protein signal transduction GO:0007265 29 0.058
cellular response to glucocorticoid stimulus GO:0071385 68 0.058
negative regulation of programmed cell death GO:0043069 183 0.057
negative regulation of signaling GO:0023057 157 0.057
nucleoside triphosphate catabolic process GO:0009143 123 0.057
embryo development GO:0009790 49 0.056
positive regulation of organelle organization GO:0010638 48 0.056
positive regulation of interleukin 1 secretion GO:0050716 3 0.056
regulation of g2 m transition of mitotic cell cycle GO:0010389 4 0.056
digestive tract development GO:0048565 39 0.056
negative regulation of neuron differentiation GO:0045665 62 0.056
cellular response to cytokine stimulus GO:0071345 127 0.056
regulation of jnk cascade GO:0046328 19 0.056
cell growth GO:0016049 104 0.056
heart morphogenesis GO:0003007 3 0.056
regulation of rna metabolic process GO:0051252 391 0.055
regulation of catabolic process GO:0009894 113 0.055
cellular response to peptide hormone stimulus GO:0071375 120 0.055
negative regulation of endothelial cell proliferation GO:0001937 5 0.055
microtubule cytoskeleton organization GO:0000226 25 0.055
negative regulation of cellular component organization GO:0051129 83 0.055
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.055
auditory receptor cell differentiation GO:0042491 2 0.054
mitotic sister chromatid segregation GO:0000070 1 0.054
regulation of peptide transport GO:0090087 87 0.054
regulation of microtubule based process GO:0032886 14 0.052
mitotic spindle organization GO:0007052 2 0.052
regulation of tube size GO:0035150 89 0.052
negative regulation of cardiac muscle tissue development GO:0055026 3 0.052
negative regulation of neurogenesis GO:0050768 78 0.051
response to hydrogen peroxide GO:0042542 89 0.051
secretion by cell GO:0032940 248 0.051
cell cell junction organization GO:0045216 20 0.051
positive regulation of protein phosphorylation GO:0001934 135 0.050
spindle organization GO:0007051 2 0.050
regulation of apoptotic signaling pathway GO:2001233 13 0.050
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.049
axon development GO:0061564 96 0.049
regulation of stem cell proliferation GO:0072091 14 0.049
response to external biotic stimulus GO:0043207 221 0.049
organic cyclic compound catabolic process GO:1901361 175 0.048
appendage morphogenesis GO:0035107 4 0.048
negative regulation of potassium ion transmembrane transport GO:1901380 3 0.048
organophosphate catabolic process GO:0046434 148 0.048
regulation of neuron death GO:1901214 115 0.048
tissue regeneration GO:0042246 36 0.048
response to interleukin 1 GO:0070555 55 0.048
positive regulation of secretion by cell GO:1903532 128 0.048
learning or memory GO:0007611 90 0.047
nucleobase containing small molecule metabolic process GO:0055086 316 0.047
regulation of axonogenesis GO:0050770 37 0.047
regulation of blood vessel size GO:0050880 89 0.046
positive regulation of map kinase activity GO:0043406 46 0.046
neuron death GO:0070997 127 0.046
gastrulation GO:0007369 2 0.046
regulation of defense response GO:0031347 68 0.046
neural crest cell migration GO:0001755 1 0.045
reactive oxygen species metabolic process GO:0072593 37 0.045
response to ketone GO:1901654 182 0.045
negative regulation of cardiac muscle tissue growth GO:0055022 3 0.045
response to peptide GO:1901652 292 0.044
steroid metabolic process GO:0008202 73 0.044
purine ribonucleoside metabolic process GO:0046128 168 0.044
cellular divalent inorganic cation homeostasis GO:0072503 162 0.044
developmental growth GO:0048589 100 0.043
nucleoside triphosphate metabolic process GO:0009141 144 0.043
limb morphogenesis GO:0035108 4 0.043
establishment of organelle localization GO:0051656 37 0.042
intracellular protein transport GO:0006886 79 0.042
single organism carbohydrate metabolic process GO:0044723 118 0.042
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.042
heart process GO:0003015 57 0.041
glutamate receptor signaling pathway GO:0007215 43 0.041
lymphocyte activation GO:0046649 43 0.041
epithelial cell differentiation GO:0030855 71 0.041
single organism biosynthetic process GO:0044711 342 0.041
regulation of establishment of protein localization GO:0070201 69 0.041
collateral sprouting GO:0048668 2 0.040
synaptic transmission GO:0007268 235 0.040
ribonucleoside catabolic process GO:0042454 126 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.040
interleukin 1 production GO:0032612 11 0.040
negative regulation of intracellular signal transduction GO:1902532 38 0.040
cell activation GO:0001775 97 0.040
protein oligomerization GO:0051259 191 0.040
positive regulation of endocytosis GO:0045807 28 0.040
positive regulation of focal adhesion assembly GO:0051894 2 0.039

Jak1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.045
musculoskeletal system disease DOID:17 0 0.040
connective tissue disease DOID:65 0 0.040