|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
234 |
0.960
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
117 |
0.956
|
Human |
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
116 |
0.945
|
Human |
|
|
regulation of nucleic acid templated transcription
|
GO:1903506 |
380 |
0.937
|
|
|
|
regulation of rna biosynthetic process
|
GO:2001141 |
381 |
0.925
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
168 |
0.911
|
Human |
|
|
rna biosynthetic process
|
GO:0032774 |
380 |
0.905
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
141 |
0.904
|
Human |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
252 |
0.883
|
|
|
|
transcription dna templated
|
GO:0006351 |
377 |
0.876
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.875
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
75 |
0.873
|
Human |
|
|
nucleic acid templated transcription
|
GO:0097659 |
379 |
0.849
|
|
|
|
regulation of rna metabolic process
|
GO:0051252 |
391 |
0.849
|
|
|
|
rna metabolic process
|
GO:0016070 |
406 |
0.841
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
123 |
0.812
|
Human |
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
153 |
0.789
|
Human |
|
|
conditioned taste aversion
|
GO:0001661 |
2 |
0.787
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
161 |
0.726
|
Human |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
161 |
0.724
|
Human |
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
203 |
0.716
|
|
|
|
regulation of transcription dna templated
|
GO:0006355 |
374 |
0.678
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
194 |
0.667
|
Mouse |
|
|
negative regulation of metabolic process
|
GO:0009892 |
331 |
0.665
|
Human Mouse |
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
197 |
0.661
|
|
|
|
inactivation of mapk activity
|
GO:0000188 |
2 |
0.656
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
148 |
0.655
|
Human |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
247 |
0.642
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
89 |
0.640
|
|
|
|
response to light stimulus
|
GO:0009416 |
52 |
0.630
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
304 |
0.621
|
Human |
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
1 |
0.618
|
Fly |
|
|
response to reactive oxygen species
|
GO:0000302 |
120 |
0.611
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
229 |
0.588
|
Mouse |
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
267 |
0.585
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
201 |
0.574
|
Yeast |
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
197 |
0.556
|
|
|
|
cellular response to stress
|
GO:0033554 |
269 |
0.535
|
|
|
|
cellular response to cycloheximide
|
GO:0071409 |
4 |
0.511
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
105 |
0.509
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
118 |
0.509
|
Human |
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
281 |
0.499
|
Human Mouse |
|
|
response to axon injury
|
GO:0048678 |
59 |
0.499
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
194 |
0.483
|
|
|
|
apoptotic process
|
GO:0006915 |
381 |
0.459
|
|
|
|
negative regulation of macromolecule metabolic process
|
GO:0010605 |
260 |
0.459
|
Human Mouse |
|
|
negative regulation of gene expression
|
GO:0010629 |
199 |
0.453
|
Human |
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
319 |
0.425
|
|
|
|
regulation of molecular function
|
GO:0065009 |
398 |
0.420
|
Human |
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
55 |
0.415
|
|
|
|
cellular response to follicle stimulating hormone stimulus
|
GO:0071372 |
13 |
0.414
|
|
|
|
response to inorganic substance
|
GO:0010035 |
377 |
0.399
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
123 |
0.379
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
349 |
0.379
|
Human Mouse |
|
|
programmed cell death
|
GO:0012501 |
392 |
0.373
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
387 |
0.372
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
148 |
0.367
|
|
|
|
response to cytokine
|
GO:0034097 |
215 |
0.360
|
|
|
|
response to cycloheximide
|
GO:0046898 |
6 |
0.357
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
154 |
0.355
|
|
|
|
response to radiation
|
GO:0009314 |
137 |
0.354
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.352
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
334 |
0.348
|
|
|
|
axon regeneration
|
GO:0031103 |
28 |
0.348
|
Mouse |
|
|
response to peptide
|
GO:1901652 |
292 |
0.341
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
134 |
0.335
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
80 |
0.323
|
Mouse |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
295 |
0.320
|
|
|
|
neuron differentiation
|
GO:0030182 |
368 |
0.315
|
Mouse |
|
|
wound healing
|
GO:0042060 |
122 |
0.312
|
Fly |
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
6 |
0.308
|
|
|
|
response to other organism
|
GO:0051707 |
220 |
0.304
|
|
|
|
response to growth factor
|
GO:0070848 |
189 |
0.301
|
Human |
|
|
regulation of protein metabolic process
|
GO:0051246 |
289 |
0.292
|
Mouse |
|
|
immune system process
|
GO:0002376 |
204 |
0.286
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
335 |
0.282
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
319 |
0.281
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
221 |
0.279
|
|
|
|
anatomical structure morphogenesis
|
GO:0009653 |
298 |
0.278
|
|
|
|
axon development
|
GO:0061564 |
96 |
0.273
|
Mouse |
|
|
positive regulation of molecular function
|
GO:0044093 |
230 |
0.266
|
Human |
|
|
mapk cascade
|
GO:0000165 |
140 |
0.266
|
Fly |
|
|
regulation of programmed cell death
|
GO:0043067 |
341 |
0.264
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
125 |
0.260
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
64 |
0.259
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
117 |
0.255
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
202 |
0.253
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
377 |
0.251
|
Human |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
72 |
0.250
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
134 |
0.238
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
155 |
0.233
|
Fly |
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
106 |
0.233
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
183 |
0.230
|
Mouse |
|
|
regulation of phosphorylation
|
GO:0042325 |
248 |
0.226
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
106 |
0.216
|
Mouse |
|
|
response to oxidative stress
|
GO:0006979 |
186 |
0.215
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
247 |
0.206
|
|
|
|
axonogenesis
|
GO:0007409 |
71 |
0.196
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
114 |
0.191
|
Mouse |
|
|
response to ketone
|
GO:1901654 |
182 |
0.190
|
|
|
|
tube development
|
GO:0035295 |
89 |
0.184
|
|
|
|
response to camp
|
GO:0051591 |
91 |
0.183
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
183 |
0.182
|
Mouse |
|
|
neuron projection morphogenesis
|
GO:0048812 |
122 |
0.179
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
359 |
0.178
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
386 |
0.172
|
Yeast |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
181 |
0.171
|
Mouse |
|
|
cell morphogenesis
|
GO:0000902 |
142 |
0.165
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
133 |
0.165
|
Human |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
20 |
0.161
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
184 |
0.160
|
|
|
|
regulation of signal transduction
|
GO:0009966 |
318 |
0.159
|
Human |
|
|
regeneration
|
GO:0031099 |
163 |
0.158
|
Mouse |
|
|
intracellular signal transduction
|
GO:0035556 |
314 |
0.158
|
Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
71 |
0.155
|
Human |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
127 |
0.153
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
376 |
0.149
|
|
|
|
cytokine production
|
GO:0001816 |
61 |
0.148
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
197 |
0.146
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
157 |
0.144
|
|
|
|
regulation of cell development
|
GO:0060284 |
263 |
0.142
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
218 |
0.142
|
Human |
|
|
response to purine containing compound
|
GO:0014074 |
126 |
0.141
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
233 |
0.140
|
Fly |
|
|
response to wounding
|
GO:0009611 |
254 |
0.138
|
Mouse Fly |
|
|
neuron projection development
|
GO:0031175 |
273 |
0.137
|
Mouse |
|
|
positive regulation of gene expression
|
GO:0010628 |
244 |
0.136
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
2 |
0.136
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
119 |
0.135
|
Mouse |
|
|
localization of cell
|
GO:0051674 |
202 |
0.135
|
|
|
|
sexual reproduction
|
GO:0019953 |
148 |
0.135
|
Fly |
|
|
response to lipopolysaccharide
|
GO:0032496 |
191 |
0.133
|
|
|
|
digestive system development
|
GO:0055123 |
41 |
0.133
|
|
|
|
response to interleukin 1
|
GO:0070555 |
55 |
0.127
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
33 |
0.126
|
|
|
|
reproductive process
|
GO:0022414 |
372 |
0.123
|
Fly |
|
|
neuron development
|
GO:0048666 |
286 |
0.122
|
Mouse |
|
|
locomotor rhythm
|
GO:0045475 |
1 |
0.119
|
|
|
|
tissue development
|
GO:0009888 |
252 |
0.117
|
Mouse Fly |
|
|
gland development
|
GO:0048732 |
155 |
0.114
|
Mouse |
|
|
cell projection morphogenesis
|
GO:0048858 |
123 |
0.112
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
162 |
0.112
|
Human |
|
|
lipid biosynthetic process
|
GO:0008610 |
128 |
0.112
|
|
|
|
synapse organization
|
GO:0050808 |
46 |
0.112
|
Fly |
|
|
cell cycle
|
GO:0007049 |
101 |
0.111
|
Mouse |
|
|
circulatory system development
|
GO:0072359 |
134 |
0.111
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
68 |
0.111
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
203 |
0.110
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
88 |
0.108
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
157 |
0.107
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
262 |
0.106
|
Fly |
|
|
cell cycle process
|
GO:0022402 |
57 |
0.106
|
|
|
|
response to toxic substance
|
GO:0009636 |
133 |
0.106
|
|
|
|
synapse assembly
|
GO:0007416 |
29 |
0.105
|
Fly |
|
|
cell part morphogenesis
|
GO:0032990 |
123 |
0.105
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
4 |
0.104
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
119 |
0.104
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
342 |
0.102
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
155 |
0.100
|
Fly |
|
|
cellular response to interleukin 1
|
GO:0071347 |
37 |
0.100
|
|
|
|
response to mineralocorticoid
|
GO:0051385 |
49 |
0.099
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
12 |
0.099
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
16 |
0.097
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
285 |
0.096
|
|
|
|
cellular response to mycophenolic acid
|
GO:0071506 |
2 |
0.096
|
|
|
|
response to bacterium
|
GO:0009617 |
200 |
0.095
|
|
|
|
response to corticosterone
|
GO:0051412 |
40 |
0.094
|
|
|
|
circadian rhythm
|
GO:0007623 |
88 |
0.093
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
51 |
0.091
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
94 |
0.090
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
320 |
0.090
|
|
|
|
single organism reproductive process
|
GO:0044702 |
297 |
0.090
|
Fly |
|
|
angiogenesis
|
GO:0001525 |
53 |
0.089
|
|
|
|
response to laminar fluid shear stress
|
GO:0034616 |
9 |
0.088
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
223 |
0.088
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
18 |
0.088
|
Human |
|
|
response to corticosteroid
|
GO:0031960 |
235 |
0.087
|
|
|
|
protein phosphorylation
|
GO:0006468 |
345 |
0.087
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
116 |
0.086
|
|
|
|
cardiovascular system development
|
GO:0072358 |
134 |
0.085
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
83 |
0.085
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
56 |
0.084
|
|
|
|
response to organophosphorus
|
GO:0046683 |
102 |
0.083
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
99 |
0.082
|
|
|
|
immune response
|
GO:0006955 |
104 |
0.082
|
Fly |
|
|
neuron projection regeneration
|
GO:0031102 |
35 |
0.081
|
Mouse |
|
|
regulation of dna metabolic process
|
GO:0051052 |
60 |
0.079
|
|
|
|
proteolysis
|
GO:0006508 |
175 |
0.079
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
178 |
0.077
|
|
|
|
liver development
|
GO:0001889 |
90 |
0.077
|
Mouse |
|
|
positive regulation of signaling
|
GO:0023056 |
270 |
0.076
|
|
|
|
response to alkaloid
|
GO:0043279 |
132 |
0.075
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
249 |
0.074
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
11 |
0.074
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
346 |
0.074
|
Human |
|
|
cellular component assembly
|
GO:0022607 |
360 |
0.072
|
Fly |
|
|
positive regulation of g0 to g1 transition
|
GO:0070318 |
2 |
0.071
|
|
|
|
epithelium development
|
GO:0060429 |
96 |
0.070
|
Mouse Fly |
|
|
positive regulation of catalytic activity
|
GO:0043085 |
184 |
0.070
|
Human |
|
|
growth
|
GO:0040007 |
165 |
0.070
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
101 |
0.068
|
Human |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
118 |
0.068
|
|
|
|
response to acid chemical
|
GO:0001101 |
222 |
0.068
|
Yeast |
|
|
skeletal muscle tissue development
|
GO:0007519 |
31 |
0.066
|
|
|
|
rhythmic process
|
GO:0048511 |
156 |
0.065
|
|
|
|
kidney development
|
GO:0001822 |
67 |
0.064
|
|
|
|
humoral immune response
|
GO:0006959 |
12 |
0.064
|
Fly |
|
|
negative regulation of cell migration involved in sprouting angiogenesis
|
GO:0090051 |
1 |
0.064
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
122 |
0.063
|
Human |
|
|
regulation of metanephros development
|
GO:0072215 |
4 |
0.061
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
3 |
0.060
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
167 |
0.060
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
53 |
0.060
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
42 |
0.059
|
|
|
|
intracellular transport
|
GO:0046907 |
185 |
0.058
|
Human |
|
|
dendrite development
|
GO:0016358 |
72 |
0.058
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
10 |
0.057
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.056
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
226 |
0.055
|
|
|
|
central nervous system development
|
GO:0007417 |
311 |
0.055
|
|
|
|
regulation of mrna 3 end processing
|
GO:0031440 |
1 |
0.053
|
|
|
|
response to estradiol
|
GO:0032355 |
164 |
0.053
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
283 |
0.052
|
|
|
|
female pregnancy
|
GO:0007565 |
122 |
0.052
|
|
|
|
circadian behavior
|
GO:0048512 |
24 |
0.052
|
|
|
|
urogenital system development
|
GO:0001655 |
78 |
0.052
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
142 |
0.051
|
|
|
|
cellular catabolic process
|
GO:0044248 |
295 |
0.051
|
Human |
|
|
cellular component biogenesis
|
GO:0044085 |
368 |
0.050
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
122 |
0.050
|
Human |
|
|
multicellular organismal reproductive process
|
GO:0048609 |
233 |
0.050
|
Fly |
|
|
response to fluid shear stress
|
GO:0034405 |
16 |
0.049
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
73 |
0.049
|
Mouse |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
349 |
0.048
|
Human Mouse |
|
|
organic acid metabolic process
|
GO:0006082 |
292 |
0.048
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
2 |
0.048
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
22 |
0.047
|
Fly |
|
|
neuron death
|
GO:0070997 |
127 |
0.047
|
|
|
|
gamete generation
|
GO:0007276 |
124 |
0.047
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
52 |
0.047
|
Mouse |
|
|
carboxylic acid metabolic process
|
GO:0019752 |
289 |
0.047
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
43 |
0.046
|
|
|
|
response to estrogen
|
GO:0043627 |
232 |
0.046
|
|
|
|
wound healing spreading of cells
|
GO:0044319 |
2 |
0.046
|
|
|
|
mrna stabilization
|
GO:0048255 |
2 |
0.046
|
|
|
|
cellular response to peptide
|
GO:1901653 |
133 |
0.046
|
|
|
|
eye development
|
GO:0001654 |
50 |
0.045
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
158 |
0.045
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
141 |
0.045
|
|
|
|
chemotaxis
|
GO:0006935 |
66 |
0.045
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
197 |
0.045
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
85 |
0.045
|
|
|
|
associative learning
|
GO:0008306 |
19 |
0.045
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
80 |
0.044
|
Mouse |
|
|
rhythmic behavior
|
GO:0007622 |
24 |
0.044
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
69 |
0.044
|
Mouse |
|
|
cellular component movement
|
GO:0006928 |
248 |
0.044
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
159 |
0.044
|
Fly |
|
|
mrna 3 end processing
|
GO:0031124 |
1 |
0.043
|
|
|
|
developmental growth
|
GO:0048589 |
100 |
0.043
|
Fly |
|
|
cellular response to metal ion
|
GO:0071248 |
55 |
0.043
|
Mouse |
|
|
negative regulation of cell development
|
GO:0010721 |
82 |
0.043
|
|
|
|
response to uv
|
GO:0009411 |
8 |
0.043
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
29 |
0.043
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
10 |
0.043
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
93 |
0.043
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
75 |
0.042
|
Yeast |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
32 |
0.042
|
|
|
|
glucose metabolic process
|
GO:0006006 |
52 |
0.041
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
210 |
0.041
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
113 |
0.041
|
Human |
|
|
protein autophosphorylation
|
GO:0046777 |
66 |
0.041
|
Mouse |
|
|
nephron development
|
GO:0072006 |
22 |
0.041
|
|
|
|
neurological system process
|
GO:0050877 |
219 |
0.040
|
|
|
|
dna metabolic process
|
GO:0006259 |
96 |
0.040
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
4 |
0.040
|
|
|
|
embryo development
|
GO:0009790 |
49 |
0.039
|
Fly |
|
|
protein dephosphorylation
|
GO:0006470 |
38 |
0.039
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.039
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
1 |
0.039
|
|
|
|
cellular protein localization
|
GO:0034613 |
122 |
0.039
|
Human |
|
|
response to carbohydrate
|
GO:0009743 |
183 |
0.038
|
|
|
|
regulation of cell migration
|
GO:0030334 |
128 |
0.038
|
|
|
|
taxis
|
GO:0042330 |
67 |
0.038
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
273 |
0.038
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
83 |
0.038
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
43 |
0.038
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
79 |
0.038
|
|
|
|
cell motility
|
GO:0048870 |
202 |
0.037
|
|
|
|
protein processing
|
GO:0016485 |
68 |
0.037
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
77 |
0.037
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
124 |
0.037
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
55 |
0.037
|
|
|
|
cell growth
|
GO:0016049 |
104 |
0.037
|
|
|
|
aging
|
GO:0007568 |
241 |
0.037
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
4 |
0.037
|
|
|
|
muscle organ development
|
GO:0007517 |
50 |
0.036
|
|
|
|
organophosphate metabolic process
|
GO:0019637 |
370 |
0.036
|
Human |
|
|
single organism intracellular transport
|
GO:1902582 |
166 |
0.036
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
27 |
0.036
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
9 |
0.035
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
26 |
0.035
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
229 |
0.034
|
Human |
|
|
sleep
|
GO:0030431 |
30 |
0.034
|
|
|
|
dephosphorylation
|
GO:0016311 |
98 |
0.034
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
2 |
0.034
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
36 |
0.034
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
103 |
0.033
|
|
|
|
response to calcium ion
|
GO:0051592 |
59 |
0.032
|
Mouse |
|
|
feeding behavior
|
GO:0007631 |
53 |
0.032
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
3 |
0.032
|
|
|
|
negative regulation of kidney development
|
GO:0090185 |
2 |
0.032
|
|
|
|
interleukin 6 production
|
GO:0032635 |
12 |
0.032
|
|
|
|
axon guidance
|
GO:0007411 |
24 |
0.032
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
46 |
0.032
|
|
|
|
response to cold
|
GO:0009409 |
29 |
0.032
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
262 |
0.031
|
Human |
|
|
cell proliferation involved in kidney development
|
GO:0072111 |
5 |
0.031
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
217 |
0.031
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
279 |
0.031
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
81 |
0.031
|
|
|
|
catabolic process
|
GO:0009056 |
351 |
0.030
|
Human |
|
|
response to glucose
|
GO:0009749 |
136 |
0.030
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
4 |
0.030
|
|
|
|
membrane organization
|
GO:0061024 |
94 |
0.030
|
|
|
|
positive regulation of mrna catabolic process
|
GO:0061014 |
2 |
0.030
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
38 |
0.030
|
|
|
|
positive regulation of nitric oxide biosynthetic process
|
GO:0045429 |
14 |
0.030
|
|
|
|
muscle system process
|
GO:0003012 |
115 |
0.030
|
|
|
|
muscle tissue development
|
GO:0060537 |
58 |
0.030
|
|
|
|
regulation of immune system process
|
GO:0002682 |
123 |
0.030
|
|
|
|
protein targeting
|
GO:0006605 |
61 |
0.029
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
245 |
0.029
|
|
|
|
regulation of response to stress
|
GO:0080134 |
126 |
0.029
|
|
|
|
metanephric glomerular mesangial cell proliferation involved in metanephros development
|
GO:0072262 |
1 |
0.029
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
96 |
0.029
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
1 |
0.029
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
20 |
0.029
|
|
|
|
response to metal ion
|
GO:0010038 |
253 |
0.029
|
Zebrafish Mouse |
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
4 |
0.028
|
|
|
|
response to peptide hormone
|
GO:0043434 |
278 |
0.028
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
150 |
0.028
|
|
|
|
cell migration
|
GO:0016477 |
197 |
0.028
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
5 |
0.028
|
|
|
|
negative regulation of oligodendrocyte differentiation
|
GO:0048715 |
3 |
0.027
|
|
|
|
response to isoquinoline alkaloid
|
GO:0014072 |
28 |
0.027
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
31 |
0.027
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
6 |
0.027
|
|
|
|
response to morphine
|
GO:0043278 |
27 |
0.027
|
|
|
|
cognition
|
GO:0050890 |
92 |
0.027
|
|
|
|
response to progesterone
|
GO:0032570 |
48 |
0.027
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
49 |
0.027
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
144 |
0.027
|
Fly |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
2 |
0.027
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
86 |
0.027
|
Human |
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
48 |
0.027
|
|
|
|
protein localization
|
GO:0008104 |
191 |
0.026
|
Human |
|
|
regulation of rna stability
|
GO:0043487 |
3 |
0.026
|
|
|
|
regulation of cellular component organization
|
GO:0051128 |
368 |
0.026
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
52 |
0.026
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
115 |
0.026
|
Human |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
38 |
0.026
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
138 |
0.026
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
178 |
0.026
|
|
|
|
amine metabolic process
|
GO:0009308 |
38 |
0.026
|
|
|
|
digestive tract development
|
GO:0048565 |
39 |
0.026
|
|
|
|
optic nerve development
|
GO:0021554 |
3 |
0.026
|
|
|
|
cell projection organization
|
GO:0030030 |
302 |
0.025
|
Mouse |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
38 |
0.025
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
56 |
0.025
|
|
|
|
heart morphogenesis
|
GO:0003007 |
3 |
0.025
|
Mouse |
|
|
learning or memory
|
GO:0007611 |
90 |
0.025
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
253 |
0.025
|
Human |
|
|
d amino acid transport
|
GO:0042940 |
1 |
0.025
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
264 |
0.025
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
17 |
0.025
|
|
|
|
response to hexose
|
GO:0009746 |
144 |
0.024
|
|
|
|
positive regulation of mrna metabolic process
|
GO:1903313 |
4 |
0.024
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
33 |
0.024
|
|
|
|
response to nutrient levels
|
GO:0031667 |
370 |
0.024
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
227 |
0.024
|
Human |
|
|
response to extracellular stimulus
|
GO:0009991 |
380 |
0.024
|
|
|
|
positive regulation of metanephros development
|
GO:0072216 |
2 |
0.024
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
52 |
0.024
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.024
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
8 |
0.024
|
|
|
|
renal system development
|
GO:0072001 |
67 |
0.024
|
|
|
|
intracellular protein transport
|
GO:0006886 |
79 |
0.024
|
Human |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
283 |
0.024
|
Human |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
115 |
0.024
|
|
|
|
learning
|
GO:0007612 |
33 |
0.024
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
3 |
0.023
|
|
|
|
circulatory system process
|
GO:0003013 |
183 |
0.023
|
Fly |
|
|
positive regulation of cell development
|
GO:0010720 |
176 |
0.023
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
37 |
0.023
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
12 |
0.023
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
80 |
0.023
|
|
|
|
response to ammonium ion
|
GO:0060359 |
71 |
0.022
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
38 |
0.022
|
|
|
|
vasculature development
|
GO:0001944 |
70 |
0.022
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
23 |
0.022
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
41 |
0.022
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
12 |
0.022
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
41 |
0.022
|
Human |
|
|
carboxylic acid transport
|
GO:0046942 |
115 |
0.022
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
6 |
0.022
|
Human |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
120 |
0.021
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
118 |
0.021
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
167 |
0.021
|
Human |
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
262 |
0.021
|
Human |
|
|
fatty acid transport
|
GO:0015908 |
25 |
0.021
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
139 |
0.021
|
Human |
|
|
nucleoside metabolic process
|
GO:0009116 |
179 |
0.021
|
Human |
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
7 |
0.021
|
|
|
|
cellular response to fluid shear stress
|
GO:0071498 |
4 |
0.020
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
168 |
0.020
|
Human |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
122 |
0.020
|
Human |
|
|
macromolecule localization
|
GO:0033036 |
252 |
0.020
|
Human |
|
|
embryonic pattern specification
|
GO:0009880 |
1 |
0.020
|
|
|
|
blood circulation
|
GO:0008015 |
183 |
0.020
|
Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
126 |
0.020
|
Human |
|
|
cell cycle phase transition
|
GO:0044770 |
21 |
0.020
|
|
|
|
positive regulation of cell proliferation involved in kidney development
|
GO:1901724 |
4 |
0.020
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
177 |
0.020
|
|
|
|
organic anion transport
|
GO:0015711 |
132 |
0.020
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
33 |
0.020
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
124 |
0.019
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
102 |
0.019
|
Human |
|
|
behavior
|
GO:0007610 |
205 |
0.019
|
|
|
|
biological adhesion
|
GO:0022610 |
110 |
0.019
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
4 |
0.019
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
208 |
0.019
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
58 |
0.019
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
42 |
0.019
|
|
|
|
locomotory behavior
|
GO:0007626 |
15 |
0.019
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
3 |
0.019
|
Fly |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.019
|
|
|
|
response to catecholamine
|
GO:0071869 |
16 |
0.019
|
|
|
|
metanephros development
|
GO:0001656 |
14 |
0.019
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
27 |
0.018
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
84 |
0.018
|
|
|
|
actin filament based movement
|
GO:0030048 |
16 |
0.018
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
39 |
0.018
|
|
|
|
immune system development
|
GO:0002520 |
41 |
0.018
|
|
|
|
protein localization to organelle
|
GO:0033365 |
57 |
0.018
|
Human |
|
|
establishment of protein localization
|
GO:0045184 |
141 |
0.018
|
Human |
|
|
dna replication
|
GO:0006260 |
37 |
0.018
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
4 |
0.018
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
247 |
0.018
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
13 |
0.018
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
181 |
0.018
|
Fly |
|
|
gastrulation
|
GO:0007369 |
2 |
0.018
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
263 |
0.018
|
|
|
|
cellular response to corticosteroid stimulus
|
GO:0071384 |
69 |
0.018
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
102 |
0.018
|
|
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
4 |
0.018
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
10 |
0.018
|
|
|
|
sensory organ development
|
GO:0007423 |
74 |
0.018
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
84 |
0.018
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
235 |
0.017
|
Human |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
23 |
0.017
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
152 |
0.017
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
136 |
0.017
|
Human |
|
|
regulation of immune response
|
GO:0050776 |
55 |
0.017
|
Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
49 |
0.017
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
175 |
0.017
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
66 |
0.017
|
|
|
|
glial cell differentiation
|
GO:0010001 |
65 |
0.017
|
|
|
|
protein transport
|
GO:0015031 |
132 |
0.017
|
Human |
|
|
regulation of hydrolase activity
|
GO:0051336 |
143 |
0.017
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.017
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
59 |
0.017
|
|
|
|
regulation of secretion
|
GO:0051046 |
224 |
0.017
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
65 |
0.017
|
Yeast Mouse |
|
|
cell adhesion
|
GO:0007155 |
110 |
0.017
|
|
|
|
response to monosaccharide
|
GO:0034284 |
159 |
0.017
|
|
|
|
reproduction
|
GO:0000003 |
245 |
0.016
|
Fly |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
182 |
0.016
|
Human |
|
|
innate immune response
|
GO:0045087 |
35 |
0.016
|
|
|
|
lipid metabolic process
|
GO:0006629 |
283 |
0.016
|
|
|
|
axis specification
|
GO:0009798 |
4 |
0.016
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
4 |
0.016
|
|
|
|
acid secretion
|
GO:0046717 |
48 |
0.016
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
152 |
0.016
|
Human |
|
|
neuron projection extension
|
GO:1990138 |
26 |
0.016
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
44 |
0.016
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
141 |
0.016
|
Human |
|
|
regulation of system process
|
GO:0044057 |
208 |
0.016
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
2 |
0.015
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
290 |
0.015
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
37 |
0.015
|
Fly |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
141 |
0.015
|
Human |
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
83 |
0.015
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
24 |
0.015
|
|
