Rattus norvegicus

53 known processes

Kcnj8

potassium inwardly-rectifying channel, subfamily J, member 8

(Aliases: uKATP-1,UKATP1,Kir6.1)

Kcnj8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to hypoxia GO:0001666 231 0.637
positive regulation of immune system process GO:0002684 90 0.584
response to oxygen levels GO:0070482 265 0.530
response to decreased oxygen levels GO:0036293 237 0.515
regulation of cellular component movement GO:0051270 150 0.441
Rat
behavior GO:0007610 205 0.433
Fly
response to inorganic substance GO:0010035 377 0.430
response to other organism GO:0051707 220 0.428
regulation of cell proliferation GO:0042127 359 0.406
positive regulation of signaling GO:0023056 270 0.401
response to wounding GO:0009611 254 0.398
positive regulation of cell communication GO:0010647 271 0.384
response to biotic stimulus GO:0009607 226 0.383
response to external biotic stimulus GO:0043207 221 0.372
cell migration GO:0016477 197 0.361
regulation of cellular component organization GO:0051128 368 0.356
regulation of response to external stimulus GO:0032101 106 0.350
vasculature development GO:0001944 70 0.333
tissue development GO:0009888 252 0.325
response to bacterium GO:0009617 200 0.318
cellular response to oxygen containing compound GO:1901701 386 0.316
Rat
defense response GO:0006952 194 0.308
Rat
regulation of programmed cell death GO:0043067 341 0.307
regulation of intracellular signal transduction GO:1902531 218 0.304
positive regulation of response to stimulus GO:0048584 285 0.300
response to lipopolysaccharide GO:0032496 191 0.298
regulation of locomotion GO:0040012 148 0.297
response to corticosteroid GO:0031960 235 0.294
Rat
regulation of phosphate metabolic process GO:0019220 349 0.292
intracellular signal transduction GO:0035556 314 0.291
positive regulation of cell motility GO:2000147 97 0.284
cell motility GO:0048870 202 0.268
regulation of cell motility GO:2000145 131 0.266
regulation of cellular localization GO:0060341 263 0.264
positive regulation of molecular function GO:0044093 230 0.263
Rat
cellular response to hormone stimulus GO:0032870 247 0.259
apoptotic process GO:0006915 381 0.256
regulation of transcription dna templated GO:0006355 374 0.253
locomotion GO:0040011 237 0.252
negative regulation of multicellular organismal process GO:0051241 203 0.249
response to estrogen GO:0043627 232 0.246
Rat
localization of cell GO:0051674 202 0.242
positive regulation of locomotion GO:0040017 102 0.242
regulation of blood pressure GO:0008217 83 0.240
regulation of cell migration GO:0030334 128 0.230
chemical homeostasis GO:0048878 292 0.229
Rat
regulation of multicellular organismal development GO:2000026 376 0.227
blood vessel development GO:0001568 69 0.227
wound healing GO:0042060 122 0.226
cellular component movement GO:0006928 248 0.225
Rat
neurological system process GO:0050877 219 0.220
Rat
response to peptide GO:1901652 292 0.220
carbohydrate derivative metabolic process GO:1901135 346 0.219
anatomical structure morphogenesis GO:0009653 298 0.217
Fly
muscle cell proliferation GO:0033002 84 0.216
nucleic acid templated transcription GO:0097659 379 0.214
positive regulation of signal transduction GO:0009967 175 0.214
cellular response to peptide GO:1901653 133 0.209
programmed cell death GO:0012501 392 0.207
response to nutrient GO:0007584 248 0.206
regulation of signal transduction GO:0009966 318 0.203
Fly
regulation of rna metabolic process GO:0051252 391 0.203
g protein coupled receptor signaling pathway GO:0007186 242 0.200
regulation of phosphorus metabolic process GO:0051174 349 0.200
positive regulation of cell migration GO:0030335 96 0.200
cellular response to endogenous stimulus GO:0071495 377 0.199
Rat
regulation of apoptotic process GO:0042981 335 0.195
cellular response to organonitrogen compound GO:0071417 197 0.194
Rat
cellular response to lipid GO:0071396 201 0.193
regulation of rna biosynthetic process GO:2001141 381 0.192
transcription dna templated GO:0006351 377 0.191
regulation of molecular function GO:0065009 398 0.191
Rat
response to acid chemical GO:0001101 222 0.185
cellular component assembly GO:0022607 360 0.184
Rat
inflammatory response GO:0006954 150 0.184
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.181
positive regulation of phosphorus metabolic process GO:0010562 262 0.170
positive regulation of phosphate metabolic process GO:0045937 262 0.170
lipid metabolic process GO:0006629 283 0.170
regulation of leukocyte migration GO:0002685 24 0.170
cellular component biogenesis GO:0044085 368 0.170
Rat
cardiovascular system development GO:0072358 134 0.167
rna metabolic process GO:0016070 406 0.166
response to nutrient levels GO:0031667 370 0.165
purine containing compound metabolic process GO:0072521 253 0.164
protein complex assembly GO:0006461 263 0.163
Rat
regulation of immune system process GO:0002682 123 0.158
response to molecule of bacterial origin GO:0002237 194 0.155
cellular chemical homeostasis GO:0055082 247 0.154
Rat
regulation of blood vessel size GO:0050880 89 0.153
regulation of cell differentiation GO:0045595 320 0.151
immune system process GO:0002376 204 0.150
neuron differentiation GO:0030182 368 0.149
Fly
cellular response to organic cyclic compound GO:0071407 202 0.149
Rat
regulation of catalytic activity GO:0050790 304 0.148
nucleobase containing small molecule metabolic process GO:0055086 316 0.147
organic acid metabolic process GO:0006082 292 0.144
rna biosynthetic process GO:0032774 380 0.144
positive regulation of cell proliferation GO:0008284 249 0.143
protein complex subunit organization GO:0071822 302 0.142
Rat
leukocyte migration GO:0050900 38 0.141
cellular response to nitrogen compound GO:1901699 210 0.139
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.139
rhythmic process GO:0048511 156 0.139
Fly
smooth muscle cell proliferation GO:0048659 77 0.139
blood vessel morphogenesis GO:0048514 58 0.137
positive regulation of multicellular organismal process GO:0051240 387 0.132
catabolic process GO:0009056 351 0.132
response to extracellular stimulus GO:0009991 380 0.130
signal transduction by phosphorylation GO:0023014 144 0.130
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.128
response to monosaccharide GO:0034284 159 0.127
Rat
aging GO:0007568 241 0.125
response to growth factor GO:0070848 189 0.123
organonitrogen compound biosynthetic process GO:1901566 167 0.123
response to ethanol GO:0045471 162 0.122
response to metal ion GO:0010038 253 0.118
response to peptide hormone GO:0043434 278 0.116
cell cell signaling GO:0007267 335 0.116
regulation of smooth muscle cell proliferation GO:0048660 75 0.114
blood circulation GO:0008015 183 0.113
homeostatic process GO:0042592 331 0.111
Rat
regulation of ion transport GO:0043269 245 0.110
sensory perception GO:0007600 101 0.109
Rat
multi organism reproductive process GO:0044703 262 0.108
regulation of phosphorylation GO:0042325 248 0.108
chemotaxis GO:0006935 66 0.106
reproduction GO:0000003 245 0.106
regulation of secretion GO:0051046 224 0.104
single organism biosynthetic process GO:0044711 342 0.103
cellular response to corticosteroid stimulus GO:0071384 69 0.103
cellular catabolic process GO:0044248 295 0.102
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.101
carboxylic acid metabolic process GO:0019752 289 0.100
gliogenesis GO:0042063 93 0.100
regeneration GO:0031099 163 0.100
multicellular organism reproduction GO:0032504 233 0.100
regulation of response to stress GO:0080134 126 0.099
positive regulation of leukocyte migration GO:0002687 21 0.098
regulation of homeostatic process GO:0032844 101 0.098
regulation of mapk cascade GO:0043408 116 0.097
cellular cation homeostasis GO:0030003 180 0.097
cellular metal ion homeostasis GO:0006875 172 0.097
regulation of response to wounding GO:1903034 69 0.097
response to glucocorticoid GO:0051384 223 0.097
Rat
neuron development GO:0048666 286 0.097
Fly
negative regulation of cellular metabolic process GO:0031324 281 0.096
organophosphate metabolic process GO:0019637 370 0.096
negative regulation of response to stimulus GO:0048585 155 0.095
Fly
response to carbohydrate GO:0009743 183 0.094
Rat
macromolecule localization GO:0033036 252 0.094
oxoacid metabolic process GO:0043436 290 0.093
growth GO:0040007 165 0.093
response to insulin GO:0032868 133 0.092
negative regulation of cell death GO:0060548 229 0.092
macromolecular complex subunit organization GO:0043933 339 0.091
Rat
multi multicellular organism process GO:0044706 138 0.090
regulation of system process GO:0044057 208 0.089
Rat
gland development GO:0048732 155 0.088
vascular process in circulatory system GO:0003018 96 0.088
protein phosphorylation GO:0006468 345 0.088
positive regulation of hydrolase activity GO:0051345 86 0.087
single organism catabolic process GO:0044712 283 0.087
circulatory system development GO:0072359 134 0.086
cation homeostasis GO:0055080 195 0.084
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.084
developmental process involved in reproduction GO:0003006 159 0.083
macromolecular complex assembly GO:0065003 273 0.083
Rat
ion homeostasis GO:0050801 212 0.082
cellular response to peptide hormone stimulus GO:0071375 120 0.082
cellular lipid metabolic process GO:0044255 208 0.081
divalent inorganic cation homeostasis GO:0072507 165 0.081
regulation of anatomical structure morphogenesis GO:0022603 141 0.080
neuron death GO:0070997 127 0.080
regulation of cellular protein metabolic process GO:0032268 267 0.080
organic substance catabolic process GO:1901575 316 0.080
anatomical structure formation involved in morphogenesis GO:0048646 83 0.079
regulation of phagocytosis engulfment GO:0060099 4 0.079
cellular component morphogenesis GO:0032989 155 0.079
Fly
positive regulation of apoptotic process GO:0043065 154 0.078
cognition GO:0050890 92 0.078
transcription from rna polymerase ii promoter GO:0006366 252 0.078
cellular calcium ion homeostasis GO:0006874 160 0.078
positive regulation of developmental process GO:0051094 283 0.078
divalent metal ion transport GO:0070838 132 0.077
reproductive system development GO:0061458 128 0.077
epithelium development GO:0060429 96 0.076
single organism organelle organization GO:1902589 180 0.076
regulation of protein modification process GO:0031399 194 0.076
secretion GO:0046903 307 0.075
single organism behavior GO:0044708 130 0.075
Fly
cell projection organization GO:0030030 302 0.075
Fly
nucleoside phosphate metabolic process GO:0006753 283 0.074
negative regulation of metabolic process GO:0009892 331 0.074
positive regulation of cellular protein metabolic process GO:0032270 167 0.074
regulation of metal ion transport GO:0010959 118 0.074
Rat
response to estradiol GO:0032355 164 0.074
Rat
single organism reproductive process GO:0044702 297 0.074
circulatory system process GO:0003013 183 0.072
central nervous system development GO:0007417 311 0.071
ribonucleotide metabolic process GO:0009259 231 0.071
positive regulation of cellular biosynthetic process GO:0031328 295 0.070
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.070
purine ribonucleoside metabolic process GO:0046128 168 0.069
regulation of anatomical structure size GO:0090066 135 0.069
striated muscle tissue development GO:0014706 58 0.067
negative regulation of apoptotic process GO:0043066 181 0.066
response to oxidative stress GO:0006979 186 0.066
positive regulation of catalytic activity GO:0043085 184 0.066
regulation of protein phosphorylation GO:0001932 183 0.066
cellular divalent inorganic cation homeostasis GO:0072503 162 0.065
protein complex biogenesis GO:0070271 263 0.065
Rat
response to cytokine GO:0034097 215 0.064
Rat
response to transition metal nanoparticle GO:1990267 122 0.064
learning or memory GO:0007611 90 0.064
female pregnancy GO:0007565 122 0.064
response to vitamin GO:0033273 131 0.063
nucleotide metabolic process GO:0009117 279 0.063
positive regulation of cellular component movement GO:0051272 102 0.062
positive regulation of nucleotide metabolic process GO:0045981 91 0.062
defense response to other organism GO:0098542 17 0.062
negative regulation of programmed cell death GO:0043069 183 0.061
lipid biosynthetic process GO:0008610 128 0.061
regulation of protein metabolic process GO:0051246 289 0.061
negative regulation of cell communication GO:0010648 158 0.060
Fly
positive regulation of protein metabolic process GO:0051247 178 0.060
organelle organization GO:0006996 266 0.059
regulation of purine nucleotide metabolic process GO:1900542 115 0.059
heterocycle catabolic process GO:0046700 167 0.058
regulation of nucleotide metabolic process GO:0006140 117 0.058
metal ion homeostasis GO:0055065 186 0.057
protein transport GO:0015031 132 0.057
angiogenesis GO:0001525 53 0.057
carbohydrate derivative catabolic process GO:1901136 147 0.056
urogenital system development GO:0001655 78 0.056
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.055
response to reactive oxygen species GO:0000302 120 0.055
positive regulation of programmed cell death GO:0043068 157 0.055
cellular homeostasis GO:0019725 252 0.054
Rat
renal system process GO:0003014 40 0.054
muscle organ development GO:0007517 50 0.054
regulation of neuron death GO:1901214 115 0.054
positive regulation of transport GO:0051050 245 0.054
Rat
multicellular organismal reproductive process GO:0048609 233 0.053
response to interleukin 1 GO:0070555 55 0.053
response to purine containing compound GO:0014074 126 0.053
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.053
negative regulation of macromolecule metabolic process GO:0010605 260 0.053
cellular amide metabolic process GO:0043603 44 0.053
peptidyl amino acid modification GO:0018193 126 0.052
cellular nitrogen compound catabolic process GO:0044270 163 0.052
positive regulation of phosphorylation GO:0042327 177 0.052
positive regulation of cell differentiation GO:0045597 217 0.052
positive regulation of protein phosphorylation GO:0001934 135 0.052
purine ribonucleotide metabolic process GO:0009150 227 0.051
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.051
peptide secretion GO:0002790 86 0.051
regulation of cell development GO:0060284 263 0.051
purine nucleotide metabolic process GO:0006163 229 0.051
cellular response to glucocorticoid stimulus GO:0071385 68 0.051
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.051
regulation of secretion by cell GO:1903530 208 0.050
calcium ion homeostasis GO:0055074 162 0.050
oxidation reduction process GO:0055114 304 0.050
regulation of body fluid levels GO:0050878 90 0.050
organ regeneration GO:0031100 101 0.050
organonitrogen compound catabolic process GO:1901565 179 0.050
maintenance of location GO:0051235 17 0.049
positive regulation of cell death GO:0010942 184 0.049
epithelial cell proliferation GO:0050673 54 0.049
regulation of defense response GO:0031347 68 0.049
negative regulation of signal transduction GO:0009968 83 0.048
Fly
immune response GO:0006955 104 0.048
negative regulation of developmental process GO:0051093 125 0.048
negative regulation of cell differentiation GO:0045596 99 0.047
response to fatty acid GO:0070542 65 0.047
regulation of hormone levels GO:0010817 187 0.047
ribose phosphate metabolic process GO:0019693 235 0.047
response to toxic substance GO:0009636 133 0.047
negative regulation of nucleic acid templated transcription GO:1903507 117 0.047
response to hexose GO:0009746 144 0.046
Rat
regulation of calcium ion transport GO:0051924 77 0.046
negative regulation of gene expression GO:0010629 199 0.046
nucleoside triphosphate metabolic process GO:0009141 144 0.046
cell projection morphogenesis GO:0048858 123 0.046
Fly
negative regulation of cellular biosynthetic process GO:0031327 161 0.046
skeletal muscle organ development GO:0060538 33 0.045
cellular response to insulin stimulus GO:0032869 81 0.045
cellular response to oxidative stress GO:0034599 76 0.045
regulation of cellular amine metabolic process GO:0033238 8 0.045
cell type specific apoptotic process GO:0097285 134 0.045
reactive oxygen species metabolic process GO:0072593 37 0.044
glycosyl compound metabolic process GO:1901657 182 0.044
purine nucleotide catabolic process GO:0006195 136 0.044
negative regulation of biosynthetic process GO:0009890 168 0.044
protein oligomerization GO:0051259 191 0.044
Rat
sequestering of calcium ion GO:0051208 8 0.044
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.043
response to glucose GO:0009749 136 0.043
Rat
regulation of hydrolase activity GO:0051336 143 0.043
brain development GO:0007420 247 0.043
steroid metabolic process GO:0008202 73 0.043
cellular response to cytokine stimulus GO:0071345 127 0.043
Rat
metal ion transport GO:0030001 289 0.043
reproductive structure development GO:0048608 128 0.043
dna metabolic process GO:0006259 96 0.042
cytoskeleton organization GO:0007010 111 0.042
positive regulation of phagocytosis engulfment GO:0060100 4 0.042
regulation of epithelial cell proliferation GO:0050678 49 0.042
epithelial cell differentiation GO:0030855 71 0.042
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.042
renal system development GO:0072001 67 0.042
response to camp GO:0051591 91 0.042
mapk cascade GO:0000165 140 0.042
vasculogenesis GO:0001570 3 0.041
positive regulation of secretion GO:0051047 140 0.041
response to alkaloid GO:0043279 132 0.041
Rat
cytosolic calcium ion homeostasis GO:0051480 140 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.041
positive regulation of rna biosynthetic process GO:1902680 197 0.041
positive regulation of response to external stimulus GO:0032103 51 0.041
regulation of inflammatory response GO:0050727 48 0.041
organophosphate catabolic process GO:0046434 148 0.040
positive regulation of secretion by cell GO:1903532 128 0.040
cellular response to steroid hormone stimulus GO:0071383 93 0.040
reproductive process GO:0022414 372 0.040
sex differentiation GO:0007548 113 0.040
regulation of cell activation GO:0050865 50 0.040
response to ketone GO:1901654 182 0.040
Rat
regulation of b cell differentiation GO:0045577 1 0.040
regulation of neuron apoptotic process GO:0043523 83 0.040
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.039
positive regulation of gene expression GO:0010628 244 0.039
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.039
enzyme linked receptor protein signaling pathway GO:0007167 116 0.039
Fly
regulation of neurogenesis GO:0050767 247 0.039
nucleobase containing compound catabolic process GO:0034655 152 0.039
cellular ketone metabolic process GO:0042180 51 0.038
positive regulation of response to wounding GO:1903036 34 0.038
neuron projection morphogenesis GO:0048812 122 0.038
Fly
regulation of peptide hormone secretion GO:0090276 80 0.038
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.037
negative regulation of phosphate metabolic process GO:0045936 80 0.037
nucleotide catabolic process GO:0009166 139 0.037
regulation of dna metabolic process GO:0051052 60 0.037
neuron projection development GO:0031175 273 0.037
Fly
stress activated protein kinase signaling cascade GO:0031098 37 0.037
aromatic compound catabolic process GO:0019439 168 0.037
small molecule biosynthetic process GO:0044283 124 0.036
response to dexamethasone GO:0071548 49 0.036
cellular ion homeostasis GO:0006873 184 0.036
transforming growth factor beta receptor complex assembly GO:0007181 2 0.036
regulation of tube size GO:0035150 89 0.036
positive regulation of epidermis development GO:0045684 1 0.035
regulation of peptide secretion GO:0002791 82 0.035
cell morphogenesis involved in differentiation GO:0000904 119 0.035
cellular amino acid metabolic process GO:0006520 107 0.035
carbohydrate homeostasis GO:0033500 75 0.035
Rat
regulation of hormone secretion GO:0046883 106 0.035
acute inflammatory response GO:0002526 58 0.034
regulation of protein kinase activity GO:0045859 105 0.034
organophosphate biosynthetic process GO:0090407 143 0.034
negative regulation of phosphorus metabolic process GO:0010563 80 0.034
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.034
cellular response to lipopolysaccharide GO:0071222 55 0.034
sequestering of metal ion GO:0051238 9 0.034
regulation of lipid metabolic process GO:0019216 68 0.034
response to activity GO:0014823 73 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.033
cellular response to stress GO:0033554 269 0.033
gamete generation GO:0007276 124 0.033
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.033
ribonucleoside metabolic process GO:0009119 174 0.032
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.032
secretion by cell GO:0032940 248 0.032
nucleoside metabolic process GO:0009116 179 0.032
regulation of behavior GO:0050795 61 0.032
positive regulation of mapk cascade GO:0043410 92 0.032
intracellular transport GO:0046907 185 0.032
response to mechanical stimulus GO:0009612 134 0.032
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.032
purine ribonucleotide biosynthetic process GO:0009152 81 0.032
muscle tissue development GO:0060537 58 0.031
regulation of erk1 and erk2 cascade GO:0070372 41 0.031
response to increased oxygen levels GO:0036296 45 0.031
nitrogen compound transport GO:0071705 229 0.031
Rat
neuron apoptotic process GO:0051402 88 0.031
regulation of growth GO:0040008 105 0.031
nucleotide biosynthetic process GO:0009165 98 0.031
female gonad development GO:0008585 53 0.031
glial cell differentiation GO:0010001 65 0.031
cation transport GO:0006812 382 0.031
negative regulation of neuron death GO:1901215 69 0.031
regulation of map kinase activity GO:0043405 53 0.031
cellular response to alcohol GO:0097306 87 0.031
vasodilation GO:0042311 44 0.031
negative regulation of ion transport GO:0043271 51 0.031
development of primary female sexual characteristics GO:0046545 56 0.031
developmental growth GO:0048589 100 0.031
regulation of protein serine threonine kinase activity GO:0071900 64 0.030
signal release GO:0023061 145 0.030
purine ribonucleotide catabolic process GO:0009154 136 0.030
organic hydroxy compound metabolic process GO:1901615 115 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
regulation of organelle organization GO:0033043 80 0.030
calcium ion transport into cytosol GO:0060402 38 0.030
immune effector process GO:0002252 53 0.030
positive regulation of transferase activity GO:0051347 81 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.030
peptide transport GO:0015833 97 0.030
nucleoside phosphate catabolic process GO:1901292 140 0.030
cellular amine metabolic process GO:0044106 38 0.030
response to organophosphorus GO:0046683 102 0.030
positive regulation of protein kinase activity GO:0045860 73 0.029
purine containing compound catabolic process GO:0072523 138 0.029
regulation of immune response GO:0050776 55 0.029
negative regulation of rna biosynthetic process GO:1902679 118 0.029
nucleoside phosphate biosynthetic process GO:1901293 102 0.029
regulation of blood circulation GO:1903522 110 0.029
Rat
cellular response to biotic stimulus GO:0071216 59 0.029
cytokine production GO:0001816 61 0.029
protein localization GO:0008104 191 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
muscle contraction GO:0006936 88 0.028
Rat
negative regulation of blood pressure GO:0045776 29 0.028
skin development GO:0043588 17 0.028
regulation of peptide transport GO:0090087 87 0.028
female sex differentiation GO:0046660 59 0.028
development of primary sexual characteristics GO:0045137 107 0.028
amine metabolic process GO:0009308 38 0.028
embryonic pattern specification GO:0009880 1 0.028
organ morphogenesis GO:0009887 75 0.028
ribonucleotide catabolic process GO:0009261 136 0.028
coronary vasculature morphogenesis GO:0060977 3 0.027
mesenchymal cell proliferation GO:0010463 4 0.027
proteolysis GO:0006508 175 0.027
alcohol metabolic process GO:0006066 77 0.027
ribonucleoside triphosphate catabolic process GO:0009203 122 0.027
head development GO:0060322 247 0.027
positive regulation of protein modification process GO:0031401 142 0.027
single organism intracellular transport GO:1902582 166 0.027
multicellular organismal homeostasis GO:0048871 49 0.027
skeletal muscle tissue development GO:0007519 31 0.027
regulation of ion homeostasis GO:2000021 63 0.027
insulin like growth factor receptor signaling pathway GO:0048009 3 0.027
negative regulation of transcription dna templated GO:0045892 116 0.026
regulation of calcium ion transport into cytosol GO:0010522 25 0.026
negative regulation of homeostatic process GO:0032845 47 0.026
limbic system development GO:0021761 38 0.026
purine containing compound biosynthetic process GO:0072522 85 0.026
regulation of kinase activity GO:0043549 117 0.026
positive regulation of defense response GO:0031349 37 0.026
sexual reproduction GO:0019953 148 0.026
axis specification GO:0009798 4 0.025
cell growth GO:0016049 104 0.025
regulation of transferase activity GO:0051338 123 0.025
positive regulation of synaptic transmission GO:0050806 62 0.025
ras protein signal transduction GO:0007265 29 0.025
tube development GO:0035295 89 0.025
protein heterooligomerization GO:0051291 89 0.025
regulation of leukocyte activation GO:0002694 45 0.025
positive regulation of ion transport GO:0043270 94 0.025
Rat
calcium ion transport GO:0006816 131 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
regulation of nervous system development GO:0051960 264 0.024
actin cytoskeleton organization GO:0030036 73 0.024
digestive system development GO:0055123 41 0.024
cell chemotaxis GO:0060326 31 0.024
kidney development GO:0001822 67 0.024
positive regulation of homeostatic process GO:0032846 49 0.024
peptide hormone secretion GO:0030072 84 0.024
ribose phosphate biosynthetic process GO:0046390 87 0.024
epidermis development GO:0008544 11 0.024
regulation of endothelial cell differentiation GO:0045601 4 0.024
negative regulation of cell proliferation GO:0008285 119 0.024
regulation of reactive oxygen species metabolic process GO:2000377 26 0.023
hepaticobiliary system development GO:0061008 90 0.023
insulin secretion GO:0030073 69 0.023
cellular response to interleukin 1 GO:0071347 37 0.023
negative regulation of smooth muscle cell proliferation GO:0048662 21 0.023
immunoglobulin mediated immune response GO:0016064 4 0.023
maternal process involved in female pregnancy GO:0060135 38 0.023
positive regulation of peptide secretion GO:0002793 52 0.023
jak stat cascade GO:0007259 26 0.023
ribonucleoside triphosphate metabolic process GO:0009199 141 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
camp metabolic process GO:0046058 63 0.022
amide transport GO:0042886 105 0.022
glycosyl compound catabolic process GO:1901658 126 0.022
sensory perception of pain GO:0019233 73 0.022
Rat
positive regulation of transcription dna templated GO:0045893 197 0.022

Kcnj8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.189
vascular disease DOID:178 0 0.189
cardiovascular system disease DOID:1287 0 0.189
artery disease DOID:0050828 0 0.052
hypertension DOID:10763 0 0.042
essential hypertension DOID:10825 0 0.042
nervous system disease DOID:863 0 0.033