Rattus norvegicus

29 known processes

Kcnk2

potassium channel, subfamily K, member 2

(Aliases: rTREK1d,Trek-1)

Kcnk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.129
cell projection organization GO:0030030 302 0.122
behavior GO:0007610 205 0.115
Fly
membrane depolarization during action potential GO:0086010 1 0.097
rhythmic process GO:0048511 156 0.097
Fly
cell morphogenesis GO:0000902 142 0.097
regulation of molecular function GO:0065009 398 0.088
cellular response to oxygen containing compound GO:1901701 386 0.087
neuron differentiation GO:0030182 368 0.086
response to carbohydrate GO:0009743 183 0.077
anatomical structure morphogenesis GO:0009653 298 0.076
regulation of system process GO:0044057 208 0.075
Fly
protein complex subunit organization GO:0071822 302 0.073
neuron projection development GO:0031175 273 0.072
regulation of rna metabolic process GO:0051252 391 0.071
circadian rhythm GO:0007623 88 0.070
Fly
regulation of cellular component organization GO:0051128 368 0.070
brain development GO:0007420 247 0.070
Rat
rna biosynthetic process GO:0032774 380 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.067
positive regulation of molecular function GO:0044093 230 0.066
nucleic acid templated transcription GO:0097659 379 0.065
regulation of rna biosynthetic process GO:2001141 381 0.064
response to monosaccharide GO:0034284 159 0.063
cellular response to endogenous stimulus GO:0071495 377 0.062
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.061
regulation of neuron differentiation GO:0045664 208 0.061
blood circulation GO:0008015 183 0.057
Fly
cellular component assembly GO:0022607 360 0.057
regulation of nucleic acid templated transcription GO:1903506 380 0.056
transcription dna templated GO:0006351 377 0.056
regulation of transcription dna templated GO:0006355 374 0.055
response to estrogen GO:0043627 232 0.054
cell part morphogenesis GO:0032990 123 0.054
cell projection morphogenesis GO:0048858 123 0.054
response to corticosteroid GO:0031960 235 0.053
chemical homeostasis GO:0048878 292 0.053
Rat
regulation of multicellular organismal development GO:2000026 376 0.053
cation transport GO:0006812 382 0.053
macromolecular complex assembly GO:0065003 273 0.053
cellular component biogenesis GO:0044085 368 0.053
circulatory system process GO:0003013 183 0.051
Fly
nitrogen compound transport GO:0071705 229 0.051
muscle contraction GO:0006936 88 0.050
positive regulation of cellular biosynthetic process GO:0031328 295 0.050
rna metabolic process GO:0016070 406 0.050
head development GO:0060322 247 0.050
Rat
response to alkaloid GO:0043279 132 0.048
Rat
positive regulation of biosynthetic process GO:0009891 319 0.048
positive regulation of multicellular organismal process GO:0051240 387 0.048
regulation of cell development GO:0060284 263 0.048
response to biotic stimulus GO:0009607 226 0.047
organophosphate metabolic process GO:0019637 370 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.046
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.045
cellular catabolic process GO:0044248 295 0.045
cardiovascular system development GO:0072358 134 0.045
regulation of nervous system development GO:0051960 264 0.044
regulation of signal transduction GO:0009966 318 0.043
cellular response to peptide hormone stimulus GO:0071375 120 0.043
axon development GO:0061564 96 0.043
positive regulation of nucleic acid templated transcription GO:1903508 197 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.043
protein complex biogenesis GO:0070271 263 0.043
cellular response to peptide GO:1901653 133 0.041
nucleoside phosphate metabolic process GO:0006753 283 0.041
single organism catabolic process GO:0044712 283 0.040
positive regulation of gene expression GO:0010628 244 0.040
glucose homeostasis GO:0042593 75 0.039
transcription from rna polymerase ii promoter GO:0006366 252 0.039
positive regulation of catalytic activity GO:0043085 184 0.039
organophosphate catabolic process GO:0046434 148 0.038
cellular response to abiotic stimulus GO:0071214 85 0.038
cellular response to organonitrogen compound GO:0071417 197 0.038
multi multicellular organism process GO:0044706 138 0.038
regulation of catalytic activity GO:0050790 304 0.038
cellular component movement GO:0006928 248 0.037
positive regulation of developmental process GO:0051094 283 0.037
reproductive process GO:0022414 372 0.037
tissue development GO:0009888 252 0.036
positive regulation of nervous system development GO:0051962 178 0.036
protein oligomerization GO:0051259 191 0.035
neuron projection morphogenesis GO:0048812 122 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
cellular response to organic cyclic compound GO:0071407 202 0.034
protein phosphorylation GO:0006468 345 0.034
response to glucose GO:0009749 136 0.033
positive regulation of phosphorus metabolic process GO:0010562 262 0.033
circulatory system development GO:0072359 134 0.033
neurological system process GO:0050877 219 0.033
response to peptide hormone GO:0043434 278 0.033
response to estradiol GO:0032355 164 0.033
protein complex assembly GO:0006461 263 0.033
neuron development GO:0048666 286 0.032
response to decreased oxygen levels GO:0036293 237 0.032
Rat
response to acid chemical GO:0001101 222 0.032
positive regulation of transcription dna templated GO:0045893 197 0.032
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.032
positive regulation of rna biosynthetic process GO:1902680 197 0.031
organonitrogen compound catabolic process GO:1901565 179 0.031
positive regulation of ion transport GO:0043270 94 0.031
regulation of blood circulation GO:1903522 110 0.031
Fly
response to nutrient levels GO:0031667 370 0.031
regulation of muscle system process GO:0090257 79 0.031
organic acid transport GO:0015849 116 0.030
positive regulation of rna metabolic process GO:0051254 203 0.030
regulation of protein kinase activity GO:0045859 105 0.030
positive regulation of transport GO:0051050 245 0.030
purine ribonucleoside metabolic process GO:0046128 168 0.030
negative regulation of response to stimulus GO:0048585 155 0.030
cardiac muscle contraction GO:0060048 27 0.029
cellular nitrogen compound catabolic process GO:0044270 163 0.029
actin filament based process GO:0030029 86 0.029
positive regulation of cellular component organization GO:0051130 200 0.028
development of primary sexual characteristics GO:0045137 107 0.028
single organism reproductive process GO:0044702 297 0.028
ion transmembrane transport GO:0034220 365 0.028
negative regulation of cell communication GO:0010648 158 0.028
positive regulation of cell development GO:0010720 176 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
learning or memory GO:0007611 90 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
cellular component morphogenesis GO:0032989 155 0.027
metal ion transport GO:0030001 289 0.027
multi organism reproductive process GO:0044703 262 0.027
regulation of ion transmembrane transport GO:0034765 121 0.027
response to mechanical stimulus GO:0009612 134 0.026
organic cyclic compound catabolic process GO:1901361 175 0.026
catabolic process GO:0009056 351 0.026
regeneration GO:0031099 163 0.026
ribonucleoside catabolic process GO:0042454 126 0.026
cellular response to nitrogen compound GO:1901699 210 0.026
multicellular organism reproduction GO:0032504 233 0.026
purine containing compound metabolic process GO:0072521 253 0.026
macromolecular complex subunit organization GO:0043933 339 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
cellular response to lipid GO:0071396 201 0.025
organelle organization GO:0006996 266 0.025
vascular process in circulatory system GO:0003018 96 0.025
cardiac chamber development GO:0003205 1 0.025
defense response GO:0006952 194 0.025
central nervous system development GO:0007417 311 0.024
Rat
regulation of actin filament based process GO:0032970 42 0.024
regulation of cell differentiation GO:0045595 320 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
response to extracellular stimulus GO:0009991 380 0.024
protein homooligomerization GO:0051260 91 0.024
nucleotide metabolic process GO:0009117 279 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
purine ribonucleotide catabolic process GO:0009154 136 0.024
response to bacterium GO:0009617 200 0.023
negative regulation of signaling GO:0023057 157 0.023
positive regulation of cellular catabolic process GO:0031331 71 0.023
nucleoside triphosphate metabolic process GO:0009141 144 0.023
regulation of neurogenesis GO:0050767 247 0.023
regulation of cell proliferation GO:0042127 359 0.023
reproduction GO:0000003 245 0.023
response to nicotine GO:0035094 51 0.023
Rat
heart process GO:0003015 57 0.023
Fly
amino acid transport GO:0006865 70 0.023
transmembrane transport GO:0055085 412 0.022
single organism organelle organization GO:1902589 180 0.022
negative regulation of nervous system development GO:0051961 79 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
organic substance catabolic process GO:1901575 316 0.022
purine nucleoside triphosphate catabolic process GO:0009146 122 0.022
response to oxygen levels GO:0070482 265 0.022
Rat
cellular response to steroid hormone stimulus GO:0071383 93 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
muscle tissue development GO:0060537 58 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
purine nucleoside metabolic process GO:0042278 169 0.021
regulation of cellular catabolic process GO:0031329 101 0.021
striated muscle contraction GO:0006941 44 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
cell cell signaling GO:0007267 335 0.021
negative regulation of developmental process GO:0051093 125 0.021
response to cytokine GO:0034097 215 0.021
response to molecule of bacterial origin GO:0002237 194 0.021
lipid metabolic process GO:0006629 283 0.021
anterior posterior pattern specification GO:0009952 1 0.021
response to oxidative stress GO:0006979 186 0.021
embryonic appendage morphogenesis GO:0035113 4 0.021
heart morphogenesis GO:0003007 3 0.020
axonogenesis GO:0007409 71 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
carboxylic acid transport GO:0046942 115 0.020
response to hexose GO:0009746 144 0.020
regulation of transporter activity GO:0032409 50 0.020
axis specification GO:0009798 4 0.020
response to growth factor GO:0070848 189 0.020
negative regulation of metabolic process GO:0009892 331 0.020
growth GO:0040007 165 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
regulation of tube size GO:0035150 89 0.019
cardiac muscle cell contraction GO:0086003 10 0.019
cellular amine metabolic process GO:0044106 38 0.019
purine nucleotide catabolic process GO:0006195 136 0.019
carbohydrate homeostasis GO:0033500 75 0.019
appendage morphogenesis GO:0035107 4 0.019
organic hydroxy compound transport GO:0015850 77 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.019
cellular homeostasis GO:0019725 252 0.019
Rat
regulation of programmed cell death GO:0043067 341 0.019
homeostatic process GO:0042592 331 0.019
Rat
glycosyl compound catabolic process GO:1901658 126 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.018
regulation of protein modification process GO:0031399 194 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
regulation of anatomical structure size GO:0090066 135 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
secretion GO:0046903 307 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
regulation of ion transport GO:0043269 245 0.018
developmental growth GO:0048589 100 0.018
regulation of catabolic process GO:0009894 113 0.018
regulation of membrane potential GO:0042391 110 0.018
regulation of synaptic transmission GO:0050804 141 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
response to glucocorticoid GO:0051384 223 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
regulation of membrane repolarization GO:0060306 1 0.017
anion transport GO:0006820 178 0.017
organic anion transport GO:0015711 132 0.017
muscle system process GO:0003012 115 0.017
bone development GO:0060348 25 0.017
biological adhesion GO:0022610 110 0.017
embryo development GO:0009790 49 0.017
developmental process involved in reproduction GO:0003006 159 0.017
response to electrical stimulus GO:0051602 56 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
ras protein signal transduction GO:0007265 29 0.017
regulation of hydrolase activity GO:0051336 143 0.017
response to hypoxia GO:0001666 231 0.017
Rat
response to other organism GO:0051707 220 0.017
regulation of muscle contraction GO:0006937 53 0.017
cell cycle GO:0007049 101 0.016
epithelium development GO:0060429 96 0.016
response to lipopolysaccharide GO:0032496 191 0.016
response to external biotic stimulus GO:0043207 221 0.016
regulation of actin filament based movement GO:1903115 12 0.016
locomotion GO:0040011 237 0.016
negative regulation of gene expression GO:0010629 199 0.016
response to ethanol GO:0045471 162 0.016
amine metabolic process GO:0009308 38 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
amine transport GO:0015837 57 0.016
cellular response to corticosteroid stimulus GO:0071384 69 0.015
cellular lipid metabolic process GO:0044255 208 0.015
positive regulation of nucleotide metabolic process GO:0045981 91 0.015
sex differentiation GO:0007548 113 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
single organism behavior GO:0044708 130 0.015
Fly
regulation of cellular localization GO:0060341 263 0.015
cellular response to carbohydrate stimulus GO:0071322 72 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
nucleotide catabolic process GO:0009166 139 0.015
cellular response to mechanical stimulus GO:0071260 48 0.015
nucleoside metabolic process GO:0009116 179 0.015
response to activity GO:0014823 73 0.014
cellular response to glucose stimulus GO:0071333 65 0.014
response to dexamethasone GO:0071548 49 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
actin filament based movement GO:0030048 16 0.014
cellular response to hexose stimulus GO:0071331 65 0.014
aging GO:0007568 241 0.014
regulation of transmembrane transport GO:0034762 122 0.014
peptide transport GO:0015833 97 0.014
muscle tissue morphogenesis GO:0060415 1 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
limb morphogenesis GO:0035108 4 0.014
striated muscle tissue development GO:0014706 58 0.014
macromolecule localization GO:0033036 252 0.014
regulation of cell projection organization GO:0031344 175 0.014
negative regulation of cell development GO:0010721 82 0.014
cellular response to stress GO:0033554 269 0.014
Rat
single organism biosynthetic process GO:0044711 342 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
programmed cell death GO:0012501 392 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
regulation of developmental growth GO:0048638 45 0.013
reproductive structure development GO:0048608 128 0.013
regulation of protein metabolic process GO:0051246 289 0.013
forebrain development GO:0030900 98 0.013
metanephric s shaped body morphogenesis GO:0072284 2 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
organ morphogenesis GO:0009887 75 0.013
response to radiation GO:0009314 137 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
cardiac ventricle development GO:0003231 1 0.013
skeletal system development GO:0001501 41 0.013
regulation of growth GO:0040008 105 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
oxoacid metabolic process GO:0043436 290 0.013
regulation of cardiac muscle contraction GO:0055117 17 0.013
actin mediated cell contraction GO:0070252 12 0.013
embryonic skeletal system morphogenesis GO:0048704 3 0.013
sensory perception GO:0007600 101 0.013
muscle structure development GO:0061061 87 0.013
kidney development GO:0001822 67 0.013
aromatic compound catabolic process GO:0019439 168 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.013
bmp signaling pathway GO:0030509 4 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
response to peptide GO:1901652 292 0.012
organic acid metabolic process GO:0006082 292 0.012
regulation of hormone levels GO:0010817 187 0.012
cellular response to glucocorticoid stimulus GO:0071385 68 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
regulation of transferase activity GO:0051338 123 0.012
purine containing compound catabolic process GO:0072523 138 0.012
muscle cell differentiation GO:0042692 52 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
locomotory exploration behavior GO:0035641 1 0.012
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.012
response to amino acid GO:0043200 75 0.012
membrane repolarization GO:0086009 1 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
response to hydrogen peroxide GO:0042542 89 0.012
regulation of secretion GO:0051046 224 0.012
intracellular transport GO:0046907 185 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
cell communication involved in cardiac conduction GO:0086065 2 0.012
regulation of blood vessel size GO:0050880 89 0.012
cellular ketone metabolic process GO:0042180 51 0.012
regulation of secretion by cell GO:1903530 208 0.012
regulation of cellular component movement GO:0051270 150 0.012
cellular response to monosaccharide stimulus GO:0071326 67 0.012
striated muscle cell development GO:0055002 26 0.012
heterocycle catabolic process GO:0046700 167 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
cell migration GO:0016477 197 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
regulation of neuron projection development GO:0010975 161 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
cell growth GO:0016049 104 0.011
cellular response to metal ion GO:0071248 55 0.011
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
circadian sleep wake cycle GO:0042745 23 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
hormone secretion GO:0046879 115 0.011
regulation of phosphorylation GO:0042325 248 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
chromatin assembly or disassembly GO:0006333 1 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
response to wounding GO:0009611 254 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
regulation of organic acid transport GO:0032890 35 0.011
cellular glucose homeostasis GO:0001678 66 0.011
response to nutrient GO:0007584 248 0.011
positive regulation of catabolic process GO:0009896 78 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
dephosphorylation GO:0016311 98 0.011
positive regulation of transmembrane transport GO:0034764 25 0.011
regulation of apoptotic process GO:0042981 335 0.011
response to vitamin GO:0033273 131 0.011
cellular response to alkaloid GO:0071312 25 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
nucleoside catabolic process GO:0009164 126 0.011
gamete generation GO:0007276 124 0.011
defecation GO:0030421 1 0.011
response to gonadotropin GO:0034698 34 0.011
dendrite development GO:0016358 72 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
embryonic limb morphogenesis GO:0030326 4 0.010
cell cycle checkpoint GO:0000075 2 0.010
steroid biosynthetic process GO:0006694 48 0.010
positive regulation of protein modification process GO:0031401 142 0.010
heart development GO:0007507 72 0.010
spindle organization GO:0007051 2 0.010
positive regulation of transferase activity GO:0051347 81 0.010
ovulation cycle GO:0042698 67 0.010
positive regulation of cell communication GO:0010647 271 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
Rat
regulation of response to stress GO:0080134 126 0.010
response to reactive oxygen species GO:0000302 120 0.010
response to hyperoxia GO:0055093 45 0.010
regulation of homotypic cell cell adhesion GO:0034110 4 0.010
response to cocaine GO:0042220 39 0.010

Kcnk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.011
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011