Rattus norvegicus

112 known processes

Klf2

Kruppel-like factor 2 (lung)

(Aliases: Lklf)

Klf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.618
intracellular signal transduction GO:0035556 314 0.544
transcription dna templated GO:0006351 377 0.445
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.410
regulation of rna metabolic process GO:0051252 391 0.391
regulation of programmed cell death GO:0043067 341 0.354
regulation of apoptotic process GO:0042981 335 0.344
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.314
regulation of rna biosynthetic process GO:2001141 381 0.307
positive regulation of nucleic acid templated transcription GO:1903508 197 0.299
transcription from rna polymerase ii promoter GO:0006366 252 0.298
Human Mouse Rat
programmed cell death GO:0012501 392 0.297
negative regulation of cellular biosynthetic process GO:0031327 161 0.292
negative regulation of nucleic acid templated transcription GO:1903507 117 0.290
nucleic acid templated transcription GO:0097659 379 0.269
regulation of intracellular signal transduction GO:1902531 218 0.259
apoptotic process GO:0006915 381 0.255
regulation of transcription dna templated GO:0006355 374 0.255
rna metabolic process GO:0016070 406 0.254
negative regulation of cellular metabolic process GO:0031324 281 0.254
rna biosynthetic process GO:0032774 380 0.253
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.246
negative regulation of signaling GO:0023057 157 0.241
negative regulation of multicellular organismal process GO:0051241 203 0.235
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.234
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.227
Human Mouse Rat
negative regulation of rna metabolic process GO:0051253 123 0.227
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.223
negative regulation of metabolic process GO:0009892 331 0.209
negative regulation of biosynthetic process GO:0009890 168 0.195
regulation of molecular function GO:0065009 398 0.178
regulation of protein metabolic process GO:0051246 289 0.171
Human
regulation of phosphate metabolic process GO:0019220 349 0.168
negative regulation of rna biosynthetic process GO:1902679 118 0.165
regulation of cellular protein metabolic process GO:0032268 267 0.162
negative regulation of signal transduction GO:0009968 83 0.161
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.156
regulation of signal transduction GO:0009966 318 0.150
tube development GO:0035295 89 0.146
Mouse
regulation of mapk cascade GO:0043408 116 0.143
negative regulation of transcription dna templated GO:0045892 116 0.139
regulation of protein modification process GO:0031399 194 0.139
positive regulation of gene expression GO:0010628 244 0.135
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.134
positive regulation of multicellular organismal process GO:0051240 387 0.133
negative regulation of cell communication GO:0010648 158 0.133
response to acid chemical GO:0001101 222 0.132
regulation of cellular component movement GO:0051270 150 0.125
negative regulation of macromolecule metabolic process GO:0010605 260 0.122
cell motility GO:0048870 202 0.121
localization of cell GO:0051674 202 0.120
central nervous system development GO:0007417 311 0.120
cell migration GO:0016477 197 0.119
cellular component movement GO:0006928 248 0.115
neuron differentiation GO:0030182 368 0.114
negative regulation of osteoblast differentiation GO:0045668 2 0.114
negative regulation of cell death GO:0060548 229 0.114
cellular response to organic cyclic compound GO:0071407 202 0.110
cell fate determination GO:0001709 2 0.109
regulation of phosphorylation GO:0042325 248 0.109
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.107
Human Mouse Rat
negative regulation of gene expression GO:0010629 199 0.106
negative regulation of intracellular signal transduction GO:1902532 38 0.102
positive regulation of phosphorus metabolic process GO:0010562 262 0.100
regulation of neurogenesis GO:0050767 247 0.097
signal transduction by phosphorylation GO:0023014 144 0.097
regulation of multicellular organismal development GO:2000026 376 0.096
erk1 and erk2 cascade GO:0070371 48 0.094
regulation of cell motility GO:2000145 131 0.093
mapk cascade GO:0000165 140 0.093
response to inorganic substance GO:0010035 377 0.092
response to growth factor GO:0070848 189 0.090
reproductive process GO:0022414 372 0.090
positive regulation of phosphate metabolic process GO:0045937 262 0.089
positive regulation of apoptotic process GO:0043065 154 0.089
positive regulation of cell death GO:0010942 184 0.087
cellular response to stress GO:0033554 269 0.086
locomotion GO:0040011 237 0.086
negative regulation of developmental process GO:0051093 125 0.085
positive regulation of biosynthetic process GO:0009891 319 0.084
positive regulation of response to stimulus GO:0048584 285 0.082
response to retinoic acid GO:0032526 63 0.082
regulation of protein phosphorylation GO:0001932 183 0.082
positive regulation of rna biosynthetic process GO:1902680 197 0.081
multicellular organism reproduction GO:0032504 233 0.081
single organism reproductive process GO:0044702 297 0.080
secretion GO:0046903 307 0.080
positive regulation of programmed cell death GO:0043068 157 0.079
regulation of cell differentiation GO:0045595 320 0.077
regulation of locomotion GO:0040012 148 0.076
glycosyl compound metabolic process GO:1901657 182 0.076
positive regulation of cellular biosynthetic process GO:0031328 295 0.073
negative regulation of response to stimulus GO:0048585 155 0.072
regulation of phosphorus metabolic process GO:0051174 349 0.071
circulatory system development GO:0072359 134 0.070
regulation of neuron differentiation GO:0045664 208 0.070
regulation of cellular amine metabolic process GO:0033238 8 0.069
ossification GO:0001503 70 0.068
negative regulation of apoptotic process GO:0043066 181 0.068
negative regulation of phosphorus metabolic process GO:0010563 80 0.068
cellular ketone metabolic process GO:0042180 51 0.068
cellular response to lipid GO:0071396 201 0.067
cellular amine metabolic process GO:0044106 38 0.066
regulation of catalytic activity GO:0050790 304 0.065
regulation of cellular amino acid metabolic process GO:0006521 2 0.065
vasculature development GO:0001944 70 0.062
positive regulation of signal transduction GO:0009967 175 0.061
negative regulation of cell proliferation GO:0008285 119 0.061
neuron fate commitment GO:0048663 4 0.061
negative regulation of molecular function GO:0044092 133 0.061
ribonucleoside triphosphate metabolic process GO:0009199 141 0.061
regulation of erk1 and erk2 cascade GO:0070372 41 0.059
purine nucleoside metabolic process GO:0042278 169 0.059
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.059
positive regulation of transcription dna templated GO:0045893 197 0.058
positive regulation of transport GO:0051050 245 0.057
positive regulation of cell differentiation GO:0045597 217 0.056
response to ketone GO:1901654 182 0.055
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.055
negative regulation of cellular protein metabolic process GO:0032269 106 0.054
ameboidal type cell migration GO:0001667 26 0.054
negative regulation of protein metabolic process GO:0051248 114 0.053
regulation of cellular ketone metabolic process GO:0010565 27 0.053
negative regulation of cell development GO:0010721 82 0.053
cellular ion homeostasis GO:0006873 184 0.053
cellular response to endogenous stimulus GO:0071495 377 0.053
response to peptide GO:1901652 292 0.052
regulation of cell development GO:0060284 263 0.052
response to nutrient levels GO:0031667 370 0.052
negative regulation of programmed cell death GO:0043069 183 0.052
regulation of cell proliferation GO:0042127 359 0.052
Rat
response to mechanical stimulus GO:0009612 134 0.052
negative regulation of phosphate metabolic process GO:0045936 80 0.051
regulation of canonical wnt signaling pathway GO:0060828 4 0.051
regulation of lipid metabolic process GO:0019216 68 0.051
cytoskeleton organization GO:0007010 111 0.049
cellular response to growth factor stimulus GO:0071363 162 0.049
reproductive system development GO:0061458 128 0.049
cellular chemical homeostasis GO:0055082 247 0.048
blood vessel development GO:0001568 69 0.048
tissue development GO:0009888 252 0.048
Mouse
bmp signaling pathway GO:0030509 4 0.048
reproductive structure development GO:0048608 128 0.048
defense response GO:0006952 194 0.047
regulation of system process GO:0044057 208 0.047
cellular response to oxygen containing compound GO:1901701 386 0.046
heart process GO:0003015 57 0.046
cellular metal ion homeostasis GO:0006875 172 0.046
response to hexose GO:0009746 144 0.046
developmental process involved in reproduction GO:0003006 159 0.046
cellular amino acid metabolic process GO:0006520 107 0.045
nucleoside metabolic process GO:0009116 179 0.044
behavior GO:0007610 205 0.044
positive regulation of signaling GO:0023056 270 0.044
multi multicellular organism process GO:0044706 138 0.044
purine ribonucleotide metabolic process GO:0009150 227 0.044
anatomical structure formation involved in morphogenesis GO:0048646 83 0.043
nucleoside catabolic process GO:0009164 126 0.043
response to cytokine GO:0034097 215 0.043
positive regulation of rna metabolic process GO:0051254 203 0.043
organic acid metabolic process GO:0006082 292 0.043
regulation of cellular component organization GO:0051128 368 0.043
organelle organization GO:0006996 266 0.042
organophosphate metabolic process GO:0019637 370 0.042
homeostatic process GO:0042592 331 0.042
Mouse
negative regulation of cell differentiation GO:0045596 99 0.042
multicellular organismal reproductive process GO:0048609 233 0.041
positive regulation of cell development GO:0010720 176 0.041
negative regulation of protein phosphorylation GO:0001933 44 0.040
cellular response to hormone stimulus GO:0032870 247 0.040
gastrulation GO:0007369 2 0.040
cellular homeostasis GO:0019725 252 0.039
blood vessel morphogenesis GO:0048514 58 0.039
ribose phosphate metabolic process GO:0019693 235 0.039
response to estrogen GO:0043627 232 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
response to glucose GO:0009749 136 0.039
muscle system process GO:0003012 115 0.039
biological adhesion GO:0022610 110 0.038
regulation of cell growth GO:0001558 85 0.038
cell type specific apoptotic process GO:0097285 134 0.038
response to hypoxia GO:0001666 231 0.037
regulation of cell migration GO:0030334 128 0.037
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.037
regulation of protein kinase activity GO:0045859 105 0.037
cellular catabolic process GO:0044248 295 0.037
purine containing compound metabolic process GO:0072521 253 0.036
positive regulation of cell communication GO:0010647 271 0.036
brain development GO:0007420 247 0.036
regulation of cell projection organization GO:0031344 175 0.035
blood circulation GO:0008015 183 0.035
regulation of kinase activity GO:0043549 117 0.035
angiogenesis GO:0001525 53 0.035
divalent inorganic cation homeostasis GO:0072507 165 0.035
negative regulation of growth GO:0045926 37 0.035
chemical homeostasis GO:0048878 292 0.034
response to corticosteroid GO:0031960 235 0.034
digestive system development GO:0055123 41 0.034
positive regulation of nucleotide metabolic process GO:0045981 91 0.034
oxoacid metabolic process GO:0043436 290 0.034
regulation of map kinase activity GO:0043405 53 0.034
positive regulation of molecular function GO:0044093 230 0.033
metal ion transport GO:0030001 289 0.033
regulation of cellular catabolic process GO:0031329 101 0.033
embryonic cranial skeleton morphogenesis GO:0048701 2 0.033
amine metabolic process GO:0009308 38 0.033
cell adhesion GO:0007155 110 0.033
positive regulation of protein metabolic process GO:0051247 178 0.033
Human
purine nucleotide catabolic process GO:0006195 136 0.032
organic substance catabolic process GO:1901575 316 0.032
multi organism reproductive process GO:0044703 262 0.032
positive regulation of protein modification process GO:0031401 142 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
regulation of muscle system process GO:0090257 79 0.032
positive regulation of cellular protein metabolic process GO:0032270 167 0.031
regulation of mesenchymal cell proliferation GO:0010464 4 0.031
nucleoside triphosphate metabolic process GO:0009141 144 0.031
epithelial cell migration GO:0010631 19 0.031
carboxylic acid metabolic process GO:0019752 289 0.031
negative regulation of phosphorylation GO:0042326 57 0.031
cytosolic calcium ion homeostasis GO:0051480 140 0.031
axis specification GO:0009798 4 0.031
regulation of vasculature development GO:1901342 44 0.030
positive regulation of bone mineralization GO:0030501 4 0.030
sensory organ development GO:0007423 74 0.030
positive regulation of cellular catabolic process GO:0031331 71 0.029
single organism organelle organization GO:1902589 180 0.029
striated muscle cell development GO:0055002 26 0.029
response to monosaccharide GO:0034284 159 0.029
single organism catabolic process GO:0044712 283 0.028
carbohydrate derivative catabolic process GO:1901136 147 0.028
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.028
hematopoietic progenitor cell differentiation GO:0002244 2 0.028
divalent metal ion transport GO:0070838 132 0.028
response to glucocorticoid GO:0051384 223 0.028
regulation of blood vessel endothelial cell migration GO:0043535 4 0.028
anterior posterior pattern specification GO:0009952 1 0.028
response to metal ion GO:0010038 253 0.027
neurological system process GO:0050877 219 0.027
immune system process GO:0002376 204 0.027
Mouse
regulation of hydrolase activity GO:0051336 143 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 116 0.027
digestive tract development GO:0048565 39 0.027
cellular component biogenesis GO:0044085 368 0.027
cell activation GO:0001775 97 0.026
cellular response to abiotic stimulus GO:0071214 85 0.026
regulation of ossification GO:0030278 32 0.026
chemotaxis GO:0006935 66 0.026
purine ribonucleoside metabolic process GO:0046128 168 0.026
response to peptide hormone GO:0043434 278 0.026
developmental growth GO:0048589 100 0.026
response to wounding GO:0009611 254 0.026
Rat
positive regulation of neuron differentiation GO:0045666 126 0.026
negative regulation of mapk cascade GO:0043409 20 0.026
aromatic compound catabolic process GO:0019439 168 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
regulation of neuron projection development GO:0010975 161 0.026
protein phosphorylation GO:0006468 345 0.026
embryonic limb morphogenesis GO:0030326 4 0.026
regulation of nervous system development GO:0051960 264 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
reactive oxygen species metabolic process GO:0072593 37 0.025
gamete generation GO:0007276 124 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
cell cycle GO:0007049 101 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
Rat
negative regulation of nervous system development GO:0051961 79 0.025
cellular response to organonitrogen compound GO:0071417 197 0.024
positive regulation of protein phosphorylation GO:0001934 135 0.024
divalent inorganic cation transport GO:0072511 134 0.024
response to nutrient GO:0007584 248 0.024
response to carbohydrate GO:0009743 183 0.024
regulation of g0 to g1 transition GO:0070316 3 0.024
positive regulation of biomineral tissue development GO:0070169 4 0.024
catabolic process GO:0009056 351 0.023
female pregnancy GO:0007565 122 0.023
embryonic skeletal system morphogenesis GO:0048704 3 0.023
cellular cation homeostasis GO:0030003 180 0.023
response to camp GO:0051591 91 0.023
cellular response to acid chemical GO:0071229 75 0.023
epithelium migration GO:0090132 19 0.023
mesoderm development GO:0007498 2 0.022
cell growth GO:0016049 104 0.022
wound healing GO:0042060 122 0.022
Rat
ras protein signal transduction GO:0007265 29 0.022
limb morphogenesis GO:0035108 4 0.022
sexual reproduction GO:0019953 148 0.022
neuron development GO:0048666 286 0.022
cation homeostasis GO:0055080 195 0.022
metal ion homeostasis GO:0055065 186 0.022
response to estradiol GO:0032355 164 0.022
organ morphogenesis GO:0009887 75 0.021
rhythmic process GO:0048511 156 0.021
reactive oxygen species biosynthetic process GO:1903409 8 0.021
secretion by cell GO:0032940 248 0.021
regulation of protein serine threonine kinase activity GO:0071900 64 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
response to ethanol GO:0045471 162 0.021
cellular protein localization GO:0034613 122 0.021
chromatin modification GO:0016568 33 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
organophosphate biosynthetic process GO:0090407 143 0.020
response to lithium ion GO:0010226 28 0.020
regulation of cell cycle GO:0051726 73 0.020
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 11 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
regulation of cellular component biogenesis GO:0044087 86 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
gland development GO:0048732 155 0.020
positive regulation of cell motility GO:2000147 97 0.020
embryo development GO:0009790 49 0.019
Mouse
carbohydrate homeostasis GO:0033500 75 0.019
positive regulation of cellular component biogenesis GO:0044089 55 0.019
nucleoside monophosphate metabolic process GO:0009123 93 0.019
embryonic pattern specification GO:0009880 1 0.019
positive regulation of developmental process GO:0051094 283 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
response to transforming growth factor beta GO:0071559 46 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
single organism cellular localization GO:1902580 102 0.018
response to oxidative stress GO:0006979 186 0.018
dendrite development GO:0016358 72 0.018
peptidyl amino acid modification GO:0018193 126 0.018
reproduction GO:0000003 245 0.018
negative regulation of protein modification process GO:0031400 52 0.018
response to purine containing compound GO:0014074 126 0.018
neuron projection development GO:0031175 273 0.018
negative regulation of peptidase activity GO:0010466 38 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
ribonucleoside triphosphate catabolic process GO:0009203 122 0.018
heart development GO:0007507 72 0.018
response to light stimulus GO:0009416 52 0.018
head development GO:0060322 247 0.018
development of primary female sexual characteristics GO:0046545 56 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
regulation of angiogenesis GO:0045765 39 0.018
posttranscriptional regulation of gene expression GO:0010608 37 0.018
vesicle mediated transport GO:0016192 181 0.018
regulation of fat cell differentiation GO:0045598 3 0.018
regulation of catabolic process GO:0009894 113 0.018
positive regulation of long term synaptic potentiation GO:1900273 4 0.018
response to vitamin GO:0033273 131 0.017
regulation of cell adhesion GO:0030155 52 0.017
regulation of cytokine production GO:0001817 56 0.017
neuron death GO:0070997 127 0.017
forebrain development GO:0030900 98 0.017
regulation of embryonic development GO:0045995 2 0.017
negative regulation of catalytic activity GO:0043086 103 0.017
sex differentiation GO:0007548 113 0.017
positive regulation of cell migration GO:0030335 96 0.017
common partner smad protein phosphorylation GO:0007182 1 0.017
positive regulation of nervous system development GO:0051962 178 0.017
ribonucleoside catabolic process GO:0042454 126 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.017
regulation of purine nucleotide catabolic process GO:0033121 65 0.017
response to extracellular stimulus GO:0009991 380 0.017
actin filament based process GO:0030029 86 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.017
regulation of stem cell differentiation GO:2000736 2 0.017
cellular response to oxidative stress GO:0034599 76 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.017
myeloid cell differentiation GO:0030099 22 0.017
Mouse
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
mesenchymal cell proliferation GO:0010463 4 0.016
smooth muscle cell proliferation GO:0048659 77 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
regulation of nucleotide catabolic process GO:0030811 65 0.016
regulation of growth GO:0040008 105 0.016
ion homeostasis GO:0050801 212 0.016
single organism intracellular transport GO:1902582 166 0.016
dna metabolic process GO:0006259 96 0.016
regulation of reactive oxygen species metabolic process GO:2000377 26 0.016
glial cell differentiation GO:0010001 65 0.016
cytokine production GO:0001816 61 0.016
calcium ion homeostasis GO:0055074 162 0.016
aging GO:0007568 241 0.016
regulation of mrna 3 end processing GO:0031440 1 0.016
regulation of synaptic plasticity GO:0048167 70 0.016
cytoplasmic transport GO:0016482 115 0.016
calcium ion transport GO:0006816 131 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.016
lipid transport GO:0006869 61 0.016
cation transport GO:0006812 382 0.016
regulation of secretion GO:0051046 224 0.016
respiratory system development GO:0060541 45 0.016
Mouse
positive regulation of hydrolase activity GO:0051345 86 0.016
appendage morphogenesis GO:0035107 4 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
b cell mediated immunity GO:0019724 4 0.016
growth GO:0040007 165 0.015
Mouse
response to toxic substance GO:0009636 133 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
regulation of lipid kinase activity GO:0043550 7 0.015
multicellular organismal signaling GO:0035637 44 0.015
immune system development GO:0002520 41 0.015
Mouse
response to vitamin d GO:0033280 34 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
response to other organism GO:0051707 220 0.015
central nervous system neuron differentiation GO:0021953 17 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
proteolysis GO:0006508 175 0.015
intracellular transport GO:0046907 185 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
regulation of odontogenesis GO:0042481 4 0.015
taxis GO:0042330 67 0.015
positive regulation of cell activation GO:0050867 34 0.015
tissue migration GO:0090130 19 0.015
protein complex subunit organization GO:0071822 302 0.015
regulation of membrane potential GO:0042391 110 0.015
lipid metabolic process GO:0006629 283 0.015
positive regulation of gtpase activity GO:0043547 47 0.015
endothelium development GO:0003158 12 0.015
regulation of homeostatic process GO:0032844 101 0.014
protein autophosphorylation GO:0046777 66 0.014
cardiovascular system development GO:0072358 134 0.014
renal system development GO:0072001 67 0.014
purine containing compound biosynthetic process GO:0072522 85 0.014
regulation of transferase activity GO:0051338 123 0.014
oxidation reduction process GO:0055114 304 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
lens fiber cell differentiation GO:0070306 3 0.014
negative regulation of nf kappab transcription factor activity GO:0032088 4 0.014
immunoglobulin mediated immune response GO:0016064 4 0.014
development of primary sexual characteristics GO:0045137 107 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
response to radiation GO:0009314 137 0.014
regulation of immunoglobulin mediated immune response GO:0002889 2 0.014
neuron apoptotic process GO:0051402 88 0.014
defense response to gram negative bacterium GO:0050829 3 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
positive regulation of endothelial cell migration GO:0010595 4 0.014
histone modification GO:0016570 30 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
nucleotide catabolic process GO:0009166 139 0.014
multicellular organism growth GO:0035264 1 0.014
Mouse
guanosine containing compound catabolic process GO:1901069 71 0.014
telencephalon development GO:0021537 62 0.014
stress activated protein kinase signaling cascade GO:0031098 37 0.013
hematopoietic or lymphoid organ development GO:0048534 36 0.013
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.013
response to reactive oxygen species GO:0000302 120 0.013
muscle structure development GO:0061061 87 0.013
olfactory bulb interneuron differentiation GO:0021889 1 0.013
noradrenergic neuron differentiation GO:0003357 1 0.013
cytokine biosynthetic process GO:0042089 3 0.013
response to oxygen levels GO:0070482 265 0.013
erythrocyte differentiation GO:0030218 1 0.013
Mouse
cell projection organization GO:0030030 302 0.013
single organism biosynthetic process GO:0044711 342 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
negative regulation of endopeptidase activity GO:0010951 36 0.013
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.013
chordate embryonic development GO:0043009 18 0.013
Mouse
circulatory system process GO:0003013 183 0.013
response to fluid shear stress GO:0034405 16 0.013
regulation of response to external stimulus GO:0032101 106 0.013
cellular component assembly GO:0022607 360 0.013
regulation of cell activation GO:0050865 50 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.013
cellular response to fluid shear stress GO:0071498 4 0.013
Human
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
tissue regeneration GO:0042246 36 0.013
negative regulation of epithelial cell proliferation GO:0050680 16 0.013
response to organophosphorus GO:0046683 102 0.013
negative regulation of calcium ion transport into cytosol GO:0010523 4 0.013
macromolecule localization GO:0033036 252 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
mechanoreceptor differentiation GO:0042490 2 0.012
ovulation cycle GO:0042698 67 0.012
regulation of immune system process GO:0002682 123 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
positive regulation of catabolic process GO:0009896 78 0.012
mesonephric tubule development GO:0072164 14 0.012
eye morphogenesis GO:0048592 4 0.012
inner ear receptor cell differentiation GO:0060113 2 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
glomerular epithelial cell differentiation GO:0072311 2 0.012
heart growth GO:0060419 20 0.012

Klf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
vascular disease DOID:178 0 0.025
cardiovascular system disease DOID:1287 0 0.025
sensory system disease DOID:0050155 0 0.025
nervous system disease DOID:863 0 0.025
hypertension DOID:10763 0 0.024
artery disease DOID:0050828 0 0.024
eye and adnexa disease DOID:1492 0 0.016
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
urinary system disease DOID:18 0 0.014