Rattus norvegicus

52 known processes

Klk1l

kallikrein 1-like peptidase

(Aliases: KALA,RATKALA,Klk1c7,Kal,Klk1,Klk5,Klk7,RSKG-7)

Klk1l biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anatomical structure morphogenesis GO:0009653 298 0.663
ion transmembrane transport GO:0034220 365 0.333
tissue development GO:0009888 252 0.271
organ morphogenesis GO:0009887 75 0.269
response to nutrient GO:0007584 248 0.256
heart morphogenesis GO:0003007 3 0.206
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.166
muscle tissue morphogenesis GO:0060415 1 0.147
response to acid chemical GO:0001101 222 0.146
tissue morphogenesis GO:0048729 22 0.140
inorganic cation transmembrane transport GO:0098662 202 0.138
intracellular signal transduction GO:0035556 314 0.124
response to extracellular stimulus GO:0009991 380 0.122
muscle tissue development GO:0060537 58 0.108
striated muscle tissue development GO:0014706 58 0.105
regulation of phosphate metabolic process GO:0019220 349 0.094
cardiovascular system development GO:0072358 134 0.093
cell projection organization GO:0030030 302 0.090
regulation of secretion GO:0051046 224 0.087
cardiac chamber development GO:0003205 1 0.087
positive regulation of phosphorus metabolic process GO:0010562 262 0.082
cardiac muscle tissue morphogenesis GO:0055008 1 0.081
cellular response to organic cyclic compound GO:0071407 202 0.080
multicellular organismal reproductive process GO:0048609 233 0.080
muscle structure development GO:0061061 87 0.077
positive regulation of rna biosynthetic process GO:1902680 197 0.076
response to inorganic substance GO:0010035 377 0.073
development of primary sexual characteristics GO:0045137 107 0.071
regulation of neuron differentiation GO:0045664 208 0.069
cellular response to endogenous stimulus GO:0071495 377 0.069
rna biosynthetic process GO:0032774 380 0.068
regulation of multicellular organismal development GO:2000026 376 0.066
epithelium development GO:0060429 96 0.065
macromolecular complex subunit organization GO:0043933 339 0.063
cell motility GO:0048870 202 0.059
cellular component biogenesis GO:0044085 368 0.059
cellular response to oxygen containing compound GO:1901701 386 0.058
macromolecular complex assembly GO:0065003 273 0.058
cation transmembrane transport GO:0098655 263 0.058
response to hypoxia GO:0001666 231 0.058
muscle organ morphogenesis GO:0048644 1 0.055
positive regulation of rna metabolic process GO:0051254 203 0.054
response to nutrient levels GO:0031667 370 0.052
regeneration GO:0031099 163 0.051
calcium ion homeostasis GO:0055074 162 0.051
reproductive structure development GO:0048608 128 0.051
transmembrane transport GO:0055085 412 0.049
neuron differentiation GO:0030182 368 0.048
response to metal ion GO:0010038 253 0.047
neuron projection development GO:0031175 273 0.047
neuron development GO:0048666 286 0.047
positive regulation of cellular biosynthetic process GO:0031328 295 0.047
regulation of signal transduction GO:0009966 318 0.047
regulation of system process GO:0044057 208 0.045
cellular response to stress GO:0033554 269 0.045
regulation of anatomical structure morphogenesis GO:0022603 141 0.044
odontogenesis GO:0042476 32 0.043
cytosolic calcium ion homeostasis GO:0051480 140 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.043
cellular response to acid chemical GO:0071229 75 0.042
regulation of anatomical structure size GO:0090066 135 0.042
regulation of phosphorylation GO:0042325 248 0.042
regulation of response to stress GO:0080134 126 0.041
positive regulation of transcription dna templated GO:0045893 197 0.041
protein complex biogenesis GO:0070271 263 0.041
rna metabolic process GO:0016070 406 0.041
regulation of transcription dna templated GO:0006355 374 0.040
nucleic acid templated transcription GO:0097659 379 0.040
monovalent inorganic cation transport GO:0015672 172 0.040
reproduction GO:0000003 245 0.040
circulatory system development GO:0072359 134 0.039
inorganic ion transmembrane transport GO:0098660 229 0.039
cellular response to lipid GO:0071396 201 0.038
sequestering of calcium ion GO:0051208 8 0.038
regulation of rna biosynthetic process GO:2001141 381 0.038
metal ion transport GO:0030001 289 0.037
cellular homeostasis GO:0019725 252 0.037
response to peptide hormone GO:0043434 278 0.036
cellular calcium ion homeostasis GO:0006874 160 0.035
regulation of rna metabolic process GO:0051252 391 0.035
response to vitamin GO:0033273 131 0.035
circulatory system process GO:0003013 183 0.035
response to wounding GO:0009611 254 0.035
cytoskeleton organization GO:0007010 111 0.035
cellular component assembly GO:0022607 360 0.034
cardiac ventricle development GO:0003231 1 0.034
stress activated protein kinase signaling cascade GO:0031098 37 0.033
regulation of cell differentiation GO:0045595 320 0.033
cellular response to organonitrogen compound GO:0071417 197 0.033
regulation of ion transport GO:0043269 245 0.033
muscle organ development GO:0007517 50 0.032
positive regulation of intracellular signal transduction GO:1902533 138 0.032
negative regulation of multicellular organismal process GO:0051241 203 0.032
regulation of protein modification process GO:0031399 194 0.032
regulation of cell development GO:0060284 263 0.032
regulation of cell motility GO:2000145 131 0.031
cellular response to nitrogen compound GO:1901699 210 0.031
regulation of cell projection organization GO:0031344 175 0.031
single organism reproductive process GO:0044702 297 0.031
multi organism reproductive process GO:0044703 262 0.031
protein complex assembly GO:0006461 263 0.030
positive regulation of cell motility GO:2000147 97 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
cellular metal ion homeostasis GO:0006875 172 0.029
regulation of neurogenesis GO:0050767 247 0.029
negative regulation of response to stimulus GO:0048585 155 0.029
cation transport GO:0006812 382 0.029
sexual reproduction GO:0019953 148 0.029
neurological system process GO:0050877 219 0.028
maintenance of location GO:0051235 17 0.028
positive regulation of phosphorylation GO:0042327 177 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
secretion GO:0046903 307 0.026
negative regulation of signal transduction GO:0009968 83 0.026
protein oligomerization GO:0051259 191 0.025
locomotion GO:0040011 237 0.025
protein complex subunit organization GO:0071822 302 0.025
response to retinoic acid GO:0032526 63 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
cellular response to peptide GO:1901653 133 0.025
brain development GO:0007420 247 0.025
epithelial cell differentiation GO:0030855 71 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
sex differentiation GO:0007548 113 0.024
reproductive system development GO:0061458 128 0.024
regulation of catalytic activity GO:0050790 304 0.024
response to peptide GO:1901652 292 0.024
negative regulation of cell death GO:0060548 229 0.024
response to amino acid GO:0043200 75 0.024
organic acid metabolic process GO:0006082 292 0.024
homeostatic process GO:0042592 331 0.024
head development GO:0060322 247 0.024
regulation of nervous system development GO:0051960 264 0.024
regulation of secretion by cell GO:1903530 208 0.023
reproductive process GO:0022414 372 0.023
regulation of neuron projection development GO:0010975 161 0.023
sequestering of metal ion GO:0051238 9 0.023
wound healing GO:0042060 122 0.023
multi multicellular organism process GO:0044706 138 0.023
positive regulation of gene expression GO:0010628 244 0.022
negative regulation of cell communication GO:0010648 158 0.022
regulation of organ formation GO:0003156 2 0.022
divalent inorganic cation homeostasis GO:0072507 165 0.022
positive regulation of protein phosphorylation GO:0001934 135 0.022
peptide biosynthetic process GO:0043043 3 0.022
organelle organization GO:0006996 266 0.022
skeletal muscle organ development GO:0060538 33 0.021
multicellular organism reproduction GO:0032504 233 0.021
response to oxygen levels GO:0070482 265 0.021
regulation of cellular component organization GO:0051128 368 0.021
negative regulation of developmental process GO:0051093 125 0.021
response to electrical stimulus involved in regulation of muscle adaptation GO:0014878 4 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
response to estrogen GO:0043627 232 0.021
skeletal muscle tissue development GO:0007519 31 0.021
tube development GO:0035295 89 0.021
purine nucleoside metabolic process GO:0042278 169 0.020
anatomical structure formation involved in morphogenesis GO:0048646 83 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
cellular component movement GO:0006928 248 0.020
response to nicotine GO:0035094 51 0.020
regulation of molecular function GO:0065009 398 0.020
heart contraction GO:0060047 57 0.019
aging GO:0007568 241 0.019
cellular response to peptide hormone stimulus GO:0071375 120 0.019
central nervous system development GO:0007417 311 0.019
regulation of locomotion GO:0040012 148 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
tissue regeneration GO:0042246 36 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
striated muscle contraction GO:0006941 44 0.018
cell morphogenesis GO:0000902 142 0.018
anion transmembrane transport GO:0098656 77 0.018
carboxylic acid metabolic process GO:0019752 289 0.017
growth GO:0040007 165 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
cognition GO:0050890 92 0.017
cellular cation homeostasis GO:0030003 180 0.017
transmission of nerve impulse GO:0019226 42 0.017
cellular component morphogenesis GO:0032989 155 0.017
small molecule biosynthetic process GO:0044283 124 0.017
response to corticosteroid GO:0031960 235 0.017
release of sequestered calcium ion into cytosol GO:0051209 25 0.017
connective tissue development GO:0061448 33 0.017
metal ion homeostasis GO:0055065 186 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
regulation of cellular response to stress GO:0080135 49 0.017
negative regulation of metabolic process GO:0009892 331 0.016
positive regulation of cell communication GO:0010647 271 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
muscle system process GO:0003012 115 0.016
regulation of ion transmembrane transport GO:0034765 121 0.016
sarcomere organization GO:0045214 6 0.016
actin cytoskeleton organization GO:0030036 73 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
behavior GO:0007610 205 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
regulation of blood circulation GO:1903522 110 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.015
adult locomotory behavior GO:0008344 4 0.015
response to growth factor GO:0070848 189 0.015
anion transport GO:0006820 178 0.015
organ induction GO:0001759 1 0.015
embryonic appendage morphogenesis GO:0035113 4 0.015
calcium ion transport into cytosol GO:0060402 38 0.015
chemical homeostasis GO:0048878 292 0.015
nucleotide metabolic process GO:0009117 279 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
sodium ion transport GO:0006814 82 0.015
response to oxidative stress GO:0006979 186 0.015
positive regulation of protein modification process GO:0031401 142 0.015
protein polymerization GO:0051258 22 0.015
oxoacid metabolic process GO:0043436 290 0.014
response to reactive oxygen species GO:0000302 120 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
regulation of transmembrane transport GO:0034762 122 0.014
regulation of kinase activity GO:0043549 117 0.014
urogenital system development GO:0001655 78 0.014
response to decreased oxygen levels GO:0036293 237 0.014
skeletal system development GO:0001501 41 0.014
negative regulation of intracellular signal transduction GO:1902532 38 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
parasympathetic nervous system development GO:0048486 1 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
protein homooligomerization GO:0051260 91 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
regulation of muscle tissue development GO:1901861 25 0.013
regulation of cellular component movement GO:0051270 150 0.013
establishment of tissue polarity GO:0007164 2 0.013
positive regulation of nervous system development GO:0051962 178 0.013
response to alkaloid GO:0043279 132 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
regulation of cell proliferation GO:0042127 359 0.013
negative regulation of neuron differentiation GO:0045665 62 0.013
inorganic anion transport GO:0015698 41 0.013
secretion by cell GO:0032940 248 0.013
blood circulation GO:0008015 183 0.013
heart development GO:0007507 72 0.013
cellular amine metabolic process GO:0044106 38 0.013
neuronal action potential GO:0019228 35 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
positive regulation of cell death GO:0010942 184 0.013
jnk cascade GO:0007254 28 0.012
response to tumor necrosis factor GO:0034612 56 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
protein activation cascade GO:0072376 12 0.012
positive regulation of secretion GO:0051047 140 0.012
action potential GO:0001508 54 0.012
positive regulation of ion transport GO:0043270 94 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
female gonad development GO:0008585 53 0.012
regulation of intracellular transport GO:0032386 65 0.012
learning or memory GO:0007611 90 0.012
actin filament based movement GO:0030048 16 0.012
apoptotic process GO:0006915 381 0.012
regulation of protein metabolic process GO:0051246 289 0.012
positive regulation of signal transduction GO:0009967 175 0.012
cardiac muscle contraction GO:0060048 27 0.012
peptide metabolic process GO:0006518 32 0.012
ossification GO:0001503 70 0.012
cellular response to drug GO:0035690 30 0.011
positive regulation of cell development GO:0010720 176 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
response to heat GO:0009408 60 0.011
muscle contraction GO:0006936 88 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
regulation of membrane potential GO:0042391 110 0.011
negative regulation of sequestering of calcium ion GO:0051283 25 0.011
response to calcium ion GO:0051592 59 0.011
cellular response to external stimulus GO:0071496 118 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
cytosolic calcium ion transport GO:0060401 39 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.011
sensory organ development GO:0007423 74 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
transcription dna templated GO:0006351 377 0.010
renal system development GO:0072001 67 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
cytoplasmic transport GO:0016482 115 0.010
embryonic skeletal system development GO:0048706 3 0.010
positive regulation of smooth muscle cell migration GO:0014911 27 0.010
negative regulation of signaling GO:0023057 157 0.010
tissue remodeling GO:0048771 40 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
response to ethanol GO:0045471 162 0.010
cellular amino acid metabolic process GO:0006520 107 0.010
amine metabolic process GO:0009308 38 0.010

Klk1l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.032
disease of anatomical entity DOID:7 0 0.032
urinary system disease DOID:18 0 0.029
kidney disease DOID:557 0 0.029
renal tubular transport disease DOID:447 0 0.026
musculoskeletal system disease DOID:17 0 0.024
muscular disease DOID:0080000 0 0.024
central nervous system disease DOID:331 0 0.017