Rattus norvegicus

0 known processes

Klrc1

killer cell lectin-like receptor subfamily C, member 1

(Aliases: rNKG2A)

Klrc1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.344
Rat
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.308
Rat
regulation of immune response to tumor cell GO:0002837 3 0.269
Rat
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.259
Rat
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.220
Rat
positive regulation of response to stimulus GO:0048584 285 0.160
positive regulation of cell proliferation GO:0008284 249 0.157
regulation of cell proliferation GO:0042127 359 0.154
g protein coupled receptor signaling pathway GO:0007186 242 0.135
rna metabolic process GO:0016070 406 0.131
monocarboxylic acid metabolic process GO:0032787 152 0.130
negative regulation of immune system process GO:0002683 39 0.115
Rat
regulation of signal transduction GO:0009966 318 0.113
response to wounding GO:0009611 254 0.112
detection of stimulus GO:0051606 24 0.109
regulation of phosphorylation GO:0042325 248 0.103
epithelium development GO:0060429 96 0.101
immune system process GO:0002376 204 0.100
Rat
negative regulation of chronic inflammatory response GO:0002677 2 0.099
ion homeostasis GO:0050801 212 0.090
stress activated protein kinase signaling cascade GO:0031098 37 0.089
brain development GO:0007420 247 0.088
homeostatic process GO:0042592 331 0.088
reproduction GO:0000003 245 0.084
programmed cell death GO:0012501 392 0.083
immune response to tumor cell GO:0002418 3 0.075
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.074
nitrogen compound transport GO:0071705 229 0.074
response to herbicide GO:0009635 16 0.073
cellular divalent inorganic cation homeostasis GO:0072503 162 0.072
positive regulation of cell communication GO:0010647 271 0.070
defecation GO:0030421 1 0.069
reproductive process GO:0022414 372 0.067
cellular chemical homeostasis GO:0055082 247 0.067
regulation of ion transport GO:0043269 245 0.067
positive regulation of phosphorus metabolic process GO:0010562 262 0.067
response to reactive oxygen species GO:0000302 120 0.065
Rat
metal ion transport GO:0030001 289 0.065
response to other organism GO:0051707 220 0.063
aging GO:0007568 241 0.061
negative regulation of long term synaptic potentiation GO:1900272 1 0.059
regulation of phosphorus metabolic process GO:0051174 349 0.056
angioblast cell migration GO:0035476 1 0.054
positive regulation of cell differentiation GO:0045597 217 0.051
prostate gland epithelium morphogenesis GO:0060740 2 0.051
leukocyte activation GO:0045321 76 0.050
Rat
negative regulation of developmental process GO:0051093 125 0.050
cellular homeostasis GO:0019725 252 0.050
sex differentiation GO:0007548 113 0.049
regulation of phosphate metabolic process GO:0019220 349 0.049
carbohydrate metabolic process GO:0005975 130 0.048
cellular calcium ion homeostasis GO:0006874 160 0.048
reproductive structure development GO:0048608 128 0.047
metal ion homeostasis GO:0055065 186 0.047
single organism biosynthetic process GO:0044711 342 0.047
response to biotic stimulus GO:0009607 226 0.047
Rat
neurological system process GO:0050877 219 0.047
small molecule biosynthetic process GO:0044283 124 0.046
negative regulation of cellular biosynthetic process GO:0031327 161 0.046
regulation of cellular localization GO:0060341 263 0.045
defense response GO:0006952 194 0.044
Rat
negative regulation of innate immune response GO:0045824 4 0.044
Rat
eosinophil migration GO:0072677 3 0.043
multi organism reproductive process GO:0044703 262 0.041
regulation of mapk cascade GO:0043408 116 0.041
regulation of membrane potential GO:0042391 110 0.041
calcium ion transport GO:0006816 131 0.040
chemical homeostasis GO:0048878 292 0.040
regulation of protein metabolic process GO:0051246 289 0.040
response to metal ion GO:0010038 253 0.040
cellular response to lipid GO:0071396 201 0.039
regulation of cell differentiation GO:0045595 320 0.039
apoptotic process GO:0006915 381 0.039
response to external biotic stimulus GO:0043207 221 0.038
regulation of response to tumor cell GO:0002834 3 0.038
Rat
response to inorganic substance GO:0010035 377 0.037
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.037
cellular response to organonitrogen compound GO:0071417 197 0.037
response to calcium ion GO:0051592 59 0.036
amine transport GO:0015837 57 0.036
response to growth factor GO:0070848 189 0.036
regulation of catalytic activity GO:0050790 304 0.035
negative regulation of cell differentiation GO:0045596 99 0.034
prostate gland morphogenesis GO:0060512 2 0.034
calcium ion homeostasis GO:0055074 162 0.034
nucleic acid templated transcription GO:0097659 379 0.033
negative regulation of metabolic process GO:0009892 331 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
negative regulation of multicellular organismal process GO:0051241 203 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
regulation of secretion GO:0051046 224 0.031
tissue development GO:0009888 252 0.030
response to radiation GO:0009314 137 0.029
regulation of synaptic transmission GO:0050804 141 0.029
single organism carbohydrate metabolic process GO:0044723 118 0.029
central nervous system development GO:0007417 311 0.029
positive regulation of signaling GO:0023056 270 0.029
regulation of neurogenesis GO:0050767 247 0.029
cytosolic calcium ion homeostasis GO:0051480 140 0.028
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.028
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.028
protein complex biogenesis GO:0070271 263 0.028
multicellular organism reproduction GO:0032504 233 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
cytokine production GO:0001816 61 0.028
intracellular signal transduction GO:0035556 314 0.028
response to extracellular stimulus GO:0009991 380 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
negative regulation of cell proliferation GO:0008285 119 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
epithelial cell differentiation GO:0030855 71 0.027
rhythmic process GO:0048511 156 0.027
negative regulation of nervous system development GO:0051961 79 0.027
negative regulation of neutrophil apoptotic process GO:0033030 3 0.027
negative regulation of response to tumor cell GO:0002835 2 0.026
Rat
nucleotide metabolic process GO:0009117 279 0.026
positive regulation of mapk cascade GO:0043410 92 0.026
regulation of immune effector process GO:0002697 32 0.026
Rat
angiogenesis GO:0001525 53 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
positive regulation of protein metabolic process GO:0051247 178 0.025
single organism intracellular transport GO:1902582 166 0.025
regulation of rna metabolic process GO:0051252 391 0.025
positive regulation of intracellular signal transduction GO:1902533 138 0.025
response to tumor cell GO:0002347 4 0.025
Rat
negative regulation of immune response to tumor cell GO:0002838 2 0.025
Rat
regulation of apoptotic process GO:0042981 335 0.025
reproductive system development GO:0061458 128 0.025
cell cell signaling GO:0007267 335 0.025
action potential GO:0001508 54 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
cellular ion homeostasis GO:0006873 184 0.024
gliogenesis GO:0042063 93 0.024
t cell chemotaxis GO:0010818 2 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
negative regulation of programmed cell death GO:0043069 183 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
regulation of synaptic plasticity GO:0048167 70 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
cellular metal ion homeostasis GO:0006875 172 0.023
sequestering of calcium ion GO:0051208 8 0.023
cation homeostasis GO:0055080 195 0.023
organophosphate biosynthetic process GO:0090407 143 0.023
anion transport GO:0006820 178 0.023
development of primary sexual characteristics GO:0045137 107 0.023
ras protein signal transduction GO:0007265 29 0.023
divalent inorganic cation transport GO:0072511 134 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
gonad development GO:0008406 104 0.023
positive regulation of transport GO:0051050 245 0.022
wound healing GO:0042060 122 0.022
blood circulation GO:0008015 183 0.022
chemosensory behavior GO:0007635 2 0.022
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.022
response to decreased oxygen levels GO:0036293 237 0.022
blood vessel morphogenesis GO:0048514 58 0.022
protein phosphorylation GO:0006468 345 0.022
adult locomotory behavior GO:0008344 4 0.022
alcohol biosynthetic process GO:0046165 38 0.022
cellular response to nitrogen compound GO:1901699 210 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
organic acid metabolic process GO:0006082 292 0.021
sexual reproduction GO:0019953 148 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
cell activation involved in immune response GO:0002263 16 0.021
rna biosynthetic process GO:0032774 380 0.021
single organism reproductive process GO:0044702 297 0.021
positive regulation of cell development GO:0010720 176 0.021
behavior GO:0007610 205 0.021
immune response GO:0006955 104 0.020
Rat
regulation of programmed cell death GO:0043067 341 0.020
detection of chemical stimulus GO:0009593 10 0.020
negative regulation of ion transport GO:0043271 51 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
second messenger mediated signaling GO:0019932 51 0.020
positive regulation of synaptic plasticity GO:0031915 3 0.020
response to nutrient levels GO:0031667 370 0.020
regulation of secretion by cell GO:1903530 208 0.020
intracellular transport GO:0046907 185 0.019
blood vessel development GO:0001568 69 0.019
regulation of carbohydrate metabolic process GO:0006109 41 0.019
inflammatory cell apoptotic process GO:0006925 5 0.019
regulation of neutrophil apoptotic process GO:0033029 4 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
synaptic transmission GO:0007268 235 0.019
regulation of neural precursor cell proliferation GO:2000177 16 0.019
response to alkaloid GO:0043279 132 0.019
cellular amine metabolic process GO:0044106 38 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.019
lymphocyte chemotaxis GO:0048247 3 0.018
lymphocyte activation GO:0046649 43 0.018
Rat
positive regulation of molecular function GO:0044093 230 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
urogenital system development GO:0001655 78 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
circadian rhythm GO:0007623 88 0.018
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.018
Rat
locomotion GO:0040011 237 0.018
transformation of host cell by virus GO:0019087 4 0.018
myeloid leukocyte activation GO:0002274 36 0.018
divalent metal ion transport GO:0070838 132 0.018
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.018
epithelial cell proliferation GO:0050673 54 0.018
head development GO:0060322 247 0.017
regulation of interferon gamma production GO:0032649 3 0.017
cellular carbohydrate metabolic process GO:0044262 72 0.017
multi multicellular organism process GO:0044706 138 0.017
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.017
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
regulation of defense response GO:0031347 68 0.017
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
negative regulation of amine transport GO:0051953 24 0.017
macromolecular complex assembly GO:0065003 273 0.017
leukocyte cell cell adhesion GO:0007159 4 0.017
Rat
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.017
Rat
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.017
spermatogenesis GO:0007283 99 0.017
response to bacterium GO:0009617 200 0.017
regulation of chronic inflammatory response GO:0002676 3 0.017
regulation of regulated secretory pathway GO:1903305 7 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
regulation of metal ion transport GO:0010959 118 0.016
regulation of calcium ion transport GO:0051924 77 0.016
regulation of leukocyte activation GO:0002694 45 0.016
protein oligomerization GO:0051259 191 0.016
alcohol metabolic process GO:0006066 77 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
negative regulation of luteinizing hormone secretion GO:0033685 4 0.016
regulation of vesicle mediated transport GO:0060627 81 0.016
development of primary female sexual characteristics GO:0046545 56 0.016
response to nutrient GO:0007584 248 0.016
response to mercury ion GO:0046689 15 0.016
forebrain development GO:0030900 98 0.016
regulation of angiogenesis GO:0045765 39 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
regulation of hormone levels GO:0010817 187 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
Rat
response to carbohydrate GO:0009743 183 0.015
sensory perception GO:0007600 101 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
coronary vasculature morphogenesis GO:0060977 3 0.015
negative regulation of secretion by cell GO:1903531 72 0.015
organic hydroxy compound biosynthetic process GO:1901617 51 0.015
negative regulation of immune response GO:0050777 15 0.015
Rat
maintenance of location GO:0051235 17 0.015
regulation of leukocyte mediated immunity GO:0002703 19 0.015
Rat
negative regulation of apoptotic process GO:0043066 181 0.015
positive regulation of signal transduction GO:0009967 175 0.015
phosphatidylinositol dephosphorylation GO:0046856 4 0.015
sodium ion transmembrane transport GO:0035725 67 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
neutrophil apoptotic process GO:0001781 4 0.015
response to lipopolysaccharide GO:0032496 191 0.015
renal system development GO:0072001 67 0.015
regulation of cell development GO:0060284 263 0.015
regulation of vasculature development GO:1901342 44 0.015
response to peptide hormone GO:0043434 278 0.015
lipid metabolic process GO:0006629 283 0.015
regulation of blood circulation GO:1903522 110 0.015
regulation of protein modification process GO:0031399 194 0.014
response to hexose GO:0009746 144 0.014
regulation of circadian sleep wake cycle GO:0042749 18 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
negative regulation of gene expression GO:0010629 199 0.014
eosinophil chemotaxis GO:0048245 3 0.014
response to indole 3 methanol GO:0071680 2 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.014
response to oxygen levels GO:0070482 265 0.014
hormone mediated signaling pathway GO:0009755 23 0.014
t helper 1 type immune response GO:0042088 1 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
insulin secretion GO:0030073 69 0.014
regulation of cell activation GO:0050865 50 0.014
mitotic cell cycle process GO:1903047 35 0.014
female pregnancy GO:0007565 122 0.014
response to estradiol GO:0032355 164 0.014
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.014
Rat
response to cytokine GO:0034097 215 0.014
learning or memory GO:0007611 90 0.014
cell projection organization GO:0030030 302 0.013
lymphocyte migration GO:0072676 3 0.013
response to hypoxia GO:0001666 231 0.013
protein complex subunit organization GO:0071822 302 0.013
regulation of immune system process GO:0002682 123 0.013
Rat
male gamete generation GO:0048232 99 0.013
negative regulation of chronic inflammatory response to non antigenic stimulus GO:0002881 1 0.013
cellular ketone metabolic process GO:0042180 51 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
negative regulation of leukocyte mediated immunity GO:0002704 6 0.013
Rat
response to ethanol GO:0045471 162 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.013
regulation of hydrolase activity GO:0051336 143 0.013
regulation of anion transport GO:0044070 43 0.013
purine containing compound metabolic process GO:0072521 253 0.013
mapk cascade GO:0000165 140 0.013
neuromuscular process GO:0050905 2 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
striated muscle contraction GO:0006941 44 0.013
camp metabolic process GO:0046058 63 0.013
positive regulation of serotonin secretion GO:0014064 1 0.013
lipid storage GO:0019915 1 0.013
developmental process involved in reproduction GO:0003006 159 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
cellular response to stress GO:0033554 269 0.013
circulatory system process GO:0003013 183 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
regulation of amine transport GO:0051952 54 0.012
positive regulation of cytokine production GO:0001819 42 0.012
response to low density lipoprotein particle GO:0055098 4 0.012
detection of stimulus involved in sensory perception GO:0050906 16 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
insecticide metabolic process GO:0017143 4 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
metanephric tubule morphogenesis GO:0072173 2 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
response to mechanical stimulus GO:0009612 134 0.012
signal release GO:0023061 145 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
multicellular organismal signaling GO:0035637 44 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of defecation GO:2000292 1 0.012
single organism behavior GO:0044708 130 0.012
cardiac conduction GO:0061337 2 0.011
female sex differentiation GO:0046660 59 0.011
neuron differentiation GO:0030182 368 0.011
steroid hormone mediated signaling pathway GO:0043401 8 0.011
regulation of dna metabolic process GO:0051052 60 0.011
coenzyme metabolic process GO:0006732 86 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
fatty acid metabolic process GO:0006631 99 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
sensory perception of bitter taste GO:0050913 4 0.011
secretion by cell GO:0032940 248 0.011
regulation of molecular function GO:0065009 398 0.011
calcium mediated signaling GO:0019722 23 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
anion transmembrane transport GO:0098656 77 0.011
developmental induction GO:0031128 2 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 18 0.011
negative regulation of cell communication GO:0010648 158 0.011
gamete generation GO:0007276 124 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
organ induction GO:0001759 1 0.011
negative regulation of defecation GO:2000293 1 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
organophosphate metabolic process GO:0019637 370 0.011
response to monosaccharide GO:0034284 159 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
response to acid chemical GO:0001101 222 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
growth GO:0040007 165 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
response to temperature stimulus GO:0009266 94 0.011
cellular response to retinoic acid GO:0071300 27 0.011
regulation of intracellular transport GO:0032386 65 0.010
serotonin metabolic process GO:0042428 3 0.010
response to fatty acid GO:0070542 65 0.010
oxidation reduction process GO:0055114 304 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
circulatory system development GO:0072359 134 0.010
sequestering of metal ion GO:0051238 9 0.010
striated muscle tissue development GO:0014706 58 0.010
eye development GO:0001654 50 0.010
cell junction organization GO:0034330 21 0.010
oxoacid metabolic process GO:0043436 290 0.010
regulation of nervous system development GO:0051960 264 0.010
calcium ion transmembrane transport GO:0070588 70 0.010
cell cycle checkpoint GO:0000075 2 0.010
negative regulation of response to biotic stimulus GO:0002832 4 0.010
Rat

Klrc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
central nervous system disease DOID:331 0 0.018
cardiovascular system disease DOID:1287 0 0.012