Rattus norvegicus

0 known processes

Krt5

keratin 5

(Aliases: Krt2-5,Sak57)

Krt5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to metal ion GO:0010038 253 0.705
response to inorganic substance GO:0010035 377 0.446
tissue development GO:0009888 252 0.410
oxoacid metabolic process GO:0043436 290 0.389
anatomical structure morphogenesis GO:0009653 298 0.378
organic acid metabolic process GO:0006082 292 0.345
single organism reproductive process GO:0044702 297 0.283
homeostatic process GO:0042592 331 0.260
response to transition metal nanoparticle GO:1990267 122 0.249
chemical homeostasis GO:0048878 292 0.249
reproductive process GO:0022414 372 0.232
tongue morphogenesis GO:0043587 3 0.224
gland development GO:0048732 155 0.196
inorganic cation transmembrane transport GO:0098662 202 0.195
organ morphogenesis GO:0009887 75 0.195
response to decreased oxygen levels GO:0036293 237 0.192
regulation of cell proliferation GO:0042127 359 0.169
urogenital system development GO:0001655 78 0.163
carboxylic acid metabolic process GO:0019752 289 0.154
wound healing GO:0042060 122 0.151
kidney development GO:0001822 67 0.147
biological adhesion GO:0022610 110 0.143
cellular component assembly GO:0022607 360 0.134
cation transport GO:0006812 382 0.133
metal ion transport GO:0030001 289 0.133
response to estradiol GO:0032355 164 0.128
response to corticosteroid GO:0031960 235 0.122
response to radiation GO:0009314 137 0.119
cation transmembrane transport GO:0098655 263 0.116
localization of cell GO:0051674 202 0.116
response to retinoic acid GO:0032526 63 0.115
transmembrane transport GO:0055085 412 0.115
cellular chemical homeostasis GO:0055082 247 0.107
cellular response to lipid GO:0071396 201 0.103
renal system development GO:0072001 67 0.102
monovalent inorganic cation transport GO:0015672 172 0.099
aging GO:0007568 241 0.096
positive regulation of cell proliferation GO:0008284 249 0.094
rna biosynthetic process GO:0032774 380 0.089
response to zinc ion GO:0010043 39 0.089
regulation of cellular localization GO:0060341 263 0.084
response to acid chemical GO:0001101 222 0.083
response to oxygen levels GO:0070482 265 0.080
sodium ion transmembrane transport GO:0035725 67 0.078
reproduction GO:0000003 245 0.078
response to ionizing radiation GO:0010212 59 0.077
response to glucocorticoid GO:0051384 223 0.076
regeneration GO:0031099 163 0.075
regulation of protein metabolic process GO:0051246 289 0.075
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.074
circulatory system development GO:0072359 134 0.074
response to estrogen GO:0043627 232 0.073
amine metabolic process GO:0009308 38 0.071
monocarboxylic acid transport GO:0015718 52 0.071
response to bacterium GO:0009617 200 0.070
peptide metabolic process GO:0006518 32 0.070
ion homeostasis GO:0050801 212 0.069
cellular amino acid metabolic process GO:0006520 107 0.069
ion transmembrane transport GO:0034220 365 0.068
response to nutrient GO:0007584 248 0.066
sodium ion transport GO:0006814 82 0.065
cellular response to organic cyclic compound GO:0071407 202 0.064
protein complex subunit organization GO:0071822 302 0.064
neuron differentiation GO:0030182 368 0.061
neuronal action potential GO:0019228 35 0.061
negative regulation of kidney development GO:0090185 2 0.059
cellular homeostasis GO:0019725 252 0.058
negative regulation of rna metabolic process GO:0051253 123 0.058
response to wounding GO:0009611 254 0.058
negative regulation of macromolecule metabolic process GO:0010605 260 0.056
regulation of cytokine production GO:0001817 56 0.056
multicellular organismal signaling GO:0035637 44 0.055
regulation of cell differentiation GO:0045595 320 0.054
growth GO:0040007 165 0.054
cellular response to endogenous stimulus GO:0071495 377 0.054
response to hypoxia GO:0001666 231 0.053
multicellular organismal reproductive process GO:0048609 233 0.052
negative regulation of multicellular organismal process GO:0051241 203 0.052
establishment of tissue polarity GO:0007164 2 0.051
positive regulation of transport GO:0051050 245 0.050
regulation of cellular amine metabolic process GO:0033238 8 0.046
cellular divalent inorganic cation homeostasis GO:0072503 162 0.046
regulation of membrane potential GO:0042391 110 0.046
cation homeostasis GO:0055080 195 0.045
sexual reproduction GO:0019953 148 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.044
neuron development GO:0048666 286 0.043
cellular response to acid chemical GO:0071229 75 0.041
cellular ion homeostasis GO:0006873 184 0.041
developmental process involved in reproduction GO:0003006 159 0.041
positive regulation of biosynthetic process GO:0009891 319 0.041
inorganic ion transmembrane transport GO:0098660 229 0.040
multicellular organism reproduction GO:0032504 233 0.040
wnt signaling pathway GO:0016055 17 0.040
nucleic acid templated transcription GO:0097659 379 0.039
cyclic purine nucleotide metabolic process GO:0052652 62 0.039
cellular response to drug GO:0035690 30 0.039
divalent inorganic cation homeostasis GO:0072507 165 0.039
regulation of secretion GO:0051046 224 0.038
carboxylic acid biosynthetic process GO:0046394 83 0.037
sensory organ development GO:0007423 74 0.036
regulation of phosphorylation GO:0042325 248 0.035
multi organism reproductive process GO:0044703 262 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
cellular amine metabolic process GO:0044106 38 0.035
defense response GO:0006952 194 0.035
response to electrical stimulus GO:0051602 56 0.035
response to purine containing compound GO:0014074 126 0.034
positive regulation of cellular amine metabolic process GO:0033240 3 0.034
single organism biosynthetic process GO:0044711 342 0.034
monocarboxylic acid metabolic process GO:0032787 152 0.034
blood vessel development GO:0001568 69 0.034
positive regulation of signal transduction GO:0009967 175 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.033
cell cell signaling GO:0007267 335 0.033
cellular response to lipopolysaccharide GO:0071222 55 0.033
neurological system process GO:0050877 219 0.033
neuron projection development GO:0031175 273 0.033
response to molecule of bacterial origin GO:0002237 194 0.033
negative regulation of developmental process GO:0051093 125 0.033
secretion by cell GO:0032940 248 0.032
cellular amide metabolic process GO:0043603 44 0.032
catabolic process GO:0009056 351 0.032
response to external biotic stimulus GO:0043207 221 0.032
organophosphate metabolic process GO:0019637 370 0.032
regulation of rna metabolic process GO:0051252 391 0.032
response to extracellular stimulus GO:0009991 380 0.032
programmed cell death GO:0012501 392 0.032
response to peptide GO:1901652 292 0.032
regulation of body fluid levels GO:0050878 90 0.032
cellular ketone metabolic process GO:0042180 51 0.031
regulation of secretion by cell GO:1903530 208 0.031
negative regulation of cell communication GO:0010648 158 0.031
purine nucleoside metabolic process GO:0042278 169 0.031
spermatogenesis GO:0007283 99 0.031
hepaticobiliary system development GO:0061008 90 0.031
response to oxidative stress GO:0006979 186 0.030
cellular response to peptide hormone stimulus GO:0071375 120 0.030
hepatocyte proliferation GO:0072574 3 0.030
hormone metabolic process GO:0042445 69 0.030
positive regulation of signaling GO:0023056 270 0.030
divalent metal ion transport GO:0070838 132 0.030
tongue development GO:0043586 8 0.030
negative regulation of hemostasis GO:1900047 6 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
protein oligomerization GO:0051259 191 0.029
gamete generation GO:0007276 124 0.028
head development GO:0060322 247 0.028
regulation of system process GO:0044057 208 0.028
cellular response to molecule of bacterial origin GO:0071219 56 0.028
positive regulation of multicellular organismal process GO:0051240 387 0.028
secretion GO:0046903 307 0.028
glomerular mesangial cell proliferation GO:0072110 4 0.028
rna metabolic process GO:0016070 406 0.028
cellular component movement GO:0006928 248 0.027
cell adhesion GO:0007155 110 0.027
regulation of immune system process GO:0002682 123 0.027
cellular component biogenesis GO:0044085 368 0.027
central nervous system development GO:0007417 311 0.027
multicellular organismal water homeostasis GO:0050891 4 0.027
single organism intracellular transport GO:1902582 166 0.026
reproductive system development GO:0061458 128 0.026
nucleoside triphosphate metabolic process GO:0009141 144 0.026
locomotion GO:0040011 237 0.026
regulation of canonical wnt signaling pathway GO:0060828 4 0.026
telencephalon development GO:0021537 62 0.026
response to ethanol GO:0045471 162 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
cytoskeleton organization GO:0007010 111 0.026
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
ribonucleoside triphosphate catabolic process GO:0009203 122 0.025
intestinal absorption GO:0050892 3 0.025
immune system process GO:0002376 204 0.025
male gamete generation GO:0048232 99 0.025
urinary bladder smooth muscle contraction GO:0014832 4 0.025
developmental growth GO:0048589 100 0.025
multi multicellular organism process GO:0044706 138 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
response to interleukin 1 GO:0070555 55 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
action potential GO:0001508 54 0.024
response to nutrient levels GO:0031667 370 0.024
transmission of nerve impulse GO:0019226 42 0.024
regulation of hormone levels GO:0010817 187 0.024
response to organophosphorus GO:0046683 102 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
protein phosphorylation GO:0006468 345 0.023
gonad development GO:0008406 104 0.023
development of primary sexual characteristics GO:0045137 107 0.023
morphogenesis of an epithelium GO:0002009 20 0.023
positive regulation of rna metabolic process GO:0051254 203 0.022
cell projection organization GO:0030030 302 0.022
negative regulation of metabolic process GO:0009892 331 0.022
cellular response to metal ion GO:0071248 55 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
response to peptide hormone GO:0043434 278 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
regulation of multicellular organismal development GO:2000026 376 0.021
regulation of homotypic cell cell adhesion GO:0034110 4 0.021
response to reactive oxygen species GO:0000302 120 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
metal ion homeostasis GO:0055065 186 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
response to fluid shear stress GO:0034405 16 0.021
regulation of vasculature development GO:1901342 44 0.021
signal release GO:0023061 145 0.021
cell motility GO:0048870 202 0.021
response to hydrogen peroxide GO:0042542 89 0.021
glomerular mesangium development GO:0072109 4 0.021
cellular response to oxygen containing compound GO:1901701 386 0.020
fatty acid metabolic process GO:0006631 99 0.020
positive regulation of developmental process GO:0051094 283 0.020
ensheathment of neurons GO:0007272 40 0.020
muscle structure development GO:0061061 87 0.020
organelle organization GO:0006996 266 0.020
divalent inorganic cation transport GO:0072511 134 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
regulation of establishment of protein localization GO:0070201 69 0.020
response to light stimulus GO:0009416 52 0.020
cellular response to steroid hormone stimulus GO:0071383 93 0.020
negative regulation of response to external stimulus GO:0032102 37 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
cellular response to external stimulus GO:0071496 118 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
cellular cation homeostasis GO:0030003 180 0.019
calcium ion homeostasis GO:0055074 162 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
regulation of transcription dna templated GO:0006355 374 0.019
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
glycosyl compound catabolic process GO:1901658 126 0.018
response to monosaccharide GO:0034284 159 0.018
synaptic transmission GO:0007268 235 0.018
vesicle mediated transport GO:0016192 181 0.018
glucose homeostasis GO:0042593 75 0.018
regulation of neuron projection development GO:0010975 161 0.018
response to mineralocorticoid GO:0051385 49 0.018
nucleoside metabolic process GO:0009116 179 0.018
regulation of sodium ion transport GO:0002028 21 0.018
protein complex biogenesis GO:0070271 263 0.018
platelet derived growth factor production GO:0090360 2 0.018
response to ketone GO:1901654 182 0.018
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.018
cellular response to biotic stimulus GO:0071216 59 0.017
establishment of protein localization GO:0045184 141 0.017
positive regulation of protein modification process GO:0031401 142 0.017
regulation of protein localization GO:0032880 81 0.017
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.017
cell migration GO:0016477 197 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
muscle system process GO:0003012 115 0.017
regulation of cell adhesion GO:0030155 52 0.017
negative regulation of transport GO:0051051 136 0.017
cellular catabolic process GO:0044248 295 0.017
protein maturation GO:0051604 68 0.017
peptide transport GO:0015833 97 0.017
rhythmic process GO:0048511 156 0.017
cellular response to retinoic acid GO:0071300 27 0.017
blood circulation GO:0008015 183 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
regulation of molecular function GO:0065009 398 0.016
regulation of cellular component movement GO:0051270 150 0.016
regulation of catalytic activity GO:0050790 304 0.016
response to insulin GO:0032868 133 0.016
regulation of ion transmembrane transport GO:0034765 121 0.016
cellular response to fluid shear stress GO:0071498 4 0.016
regulation of cell projection organization GO:0031344 175 0.016
keratinocyte differentiation GO:0030216 2 0.016
intracellular transport GO:0046907 185 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
regulation of cell motility GO:2000145 131 0.016
epithelial cell differentiation GO:0030855 71 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
response to lithium ion GO:0010226 28 0.016
regulation of transmembrane transport GO:0034762 122 0.016
liver development GO:0001889 90 0.016
regulation of protein transport GO:0051223 68 0.016
negative regulation of signaling GO:0023057 157 0.016
regulation of peptide hormone secretion GO:0090276 80 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
prostate gland development GO:0030850 9 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.015
cellular response to glucose stimulus GO:0071333 65 0.015
organic acid biosynthetic process GO:0016053 83 0.015
single organism catabolic process GO:0044712 283 0.015
cardiovascular system development GO:0072358 134 0.015
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.015
cellular modified amino acid metabolic process GO:0006575 61 0.015
hormone transport GO:0009914 121 0.015
single organism cell adhesion GO:0098602 46 0.015
brain development GO:0007420 247 0.015
hematopoietic progenitor cell differentiation GO:0002244 2 0.015
positive regulation of immune system process GO:0002684 90 0.015
macromolecular complex assembly GO:0065003 273 0.015
regulation of apoptotic process GO:0042981 335 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
purine nucleoside monophosphate metabolic process GO:0009126 84 0.015
carbohydrate homeostasis GO:0033500 75 0.015
regulation of protein modification process GO:0031399 194 0.015
heart contraction GO:0060047 57 0.015
regulation of blood circulation GO:1903522 110 0.015
anion transport GO:0006820 178 0.015
axon development GO:0061564 96 0.015
mesonephric epithelium development GO:0072163 14 0.015
nephron morphogenesis GO:0072028 13 0.014
lipid metabolic process GO:0006629 283 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
regulation of response to stress GO:0080134 126 0.014
protein transport GO:0015031 132 0.014
regulation of signal transduction GO:0009966 318 0.014
female sex differentiation GO:0046660 59 0.014
organic anion transport GO:0015711 132 0.014
negative regulation of molecular function GO:0044092 133 0.014
reproductive structure development GO:0048608 128 0.014
nucleoside catabolic process GO:0009164 126 0.014
cardiac conduction GO:0061337 2 0.014
response to testosterone GO:0033574 55 0.013
positive regulation of blood pressure by epinephrine norepinephrine GO:0003321 2 0.013
circulatory system process GO:0003013 183 0.013
calcium ion transport GO:0006816 131 0.013
regulation of hemostasis GO:1900046 9 0.013
proteolysis GO:0006508 175 0.013
immune response GO:0006955 104 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
sleep GO:0030431 30 0.013
dicarboxylic acid metabolic process GO:0043648 42 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
metanephric tubule development GO:0072170 4 0.013
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.013
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.013
sex differentiation GO:0007548 113 0.013
transcription dna templated GO:0006351 377 0.013
regulation of cell development GO:0060284 263 0.013
axon ensheathment GO:0008366 40 0.013
positive regulation of secretion GO:0051047 140 0.013
ovulation cycle process GO:0022602 50 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
cellular lipid metabolic process GO:0044255 208 0.013
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.013
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.013
potassium ion transport GO:0006813 97 0.012
negative regulation of luteinizing hormone secretion GO:0033685 4 0.012
ossification GO:0001503 70 0.012
forebrain development GO:0030900 98 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
negative regulation of secretion GO:0051048 82 0.012
response to carbohydrate GO:0009743 183 0.012
behavioral response to cocaine GO:0048148 6 0.012
response to toxic substance GO:0009636 133 0.012
response to cadmium ion GO:0046686 35 0.012
cellular response to hexose stimulus GO:0071331 65 0.012
response to axon injury GO:0048678 59 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
leukocyte migration GO:0050900 38 0.012
pituitary gland development GO:0021983 10 0.012
peptide secretion GO:0002790 86 0.012
hindlimb morphogenesis GO:0035137 2 0.012
female gonad development GO:0008585 53 0.012
connective tissue development GO:0061448 33 0.012
small molecule biosynthetic process GO:0044283 124 0.012
cellular response to peptide GO:1901653 133 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
amide transport GO:0042886 105 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
gliogenesis GO:0042063 93 0.012
response to alkaloid GO:0043279 132 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
response to other organism GO:0051707 220 0.012
s shaped body morphogenesis GO:0072050 2 0.012
multicellular organism growth GO:0035264 1 0.012
ovulation cycle GO:0042698 67 0.012
body fluid secretion GO:0007589 41 0.012
protein processing GO:0016485 68 0.012
regulation of cellular component organization GO:0051128 368 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.011
inflammatory response GO:0006954 150 0.011
nucleotide metabolic process GO:0009117 279 0.011
response to lipopolysaccharide GO:0032496 191 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
response to biotic stimulus GO:0009607 226 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
acid secretion GO:0046717 48 0.011
cellular response to tumor necrosis factor GO:0071356 46 0.011
transforming growth factor beta1 production GO:0032905 2 0.011
protein heterooligomerization GO:0051291 89 0.011
nitrogen compound transport GO:0071705 229 0.011
prostate gland morphogenesis GO:0060512 2 0.011
negative regulation of cell death GO:0060548 229 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
protein secretion GO:0009306 34 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
regulation of cell cell adhesion GO:0022407 14 0.011
regulation of glomerular mesangial cell proliferation GO:0072124 4 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
skeletal muscle satellite cell proliferation GO:0014841 1 0.011
male sex differentiation GO:0046661 64 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
embryonic hindlimb morphogenesis GO:0035116 2 0.011
cardiac muscle contraction GO:0060048 27 0.011
regulation of nervous system development GO:0051960 264 0.011
cellular response to inorganic substance GO:0071241 65 0.011
n methyl d aspartate receptor clustering GO:0097114 2 0.011
male gonad development GO:0008584 59 0.011
regulation of blood pressure GO:0008217 83 0.011
response to vitamin d GO:0033280 34 0.010
skeletal muscle organ development GO:0060538 33 0.010
regulation of neuron differentiation GO:0045664 208 0.010
myelination GO:0042552 39 0.010
response to camp GO:0051591 91 0.010
diet induced thermogenesis GO:0002024 1 0.010
hormone secretion GO:0046879 115 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
negative regulation of wound healing GO:0061045 8 0.010
regulation of response to wounding GO:1903034 69 0.010
regulation of locomotion GO:0040012 148 0.010
epiboly GO:0090504 2 0.010
regulation of systemic arterial blood pressure GO:0003073 30 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
nephron development GO:0072006 22 0.010
cellular response to stress GO:0033554 269 0.010
insulin secretion GO:0030073 69 0.010
female pregnancy GO:0007565 122 0.010
cellular response to interleukin 1 GO:0071347 37 0.010
purine containing compound metabolic process GO:0072521 253 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
negative regulation of catalytic activity GO:0043086 103 0.010

Krt5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
integumentary system disease DOID:16 0 0.040
nervous system disease DOID:863 0 0.018