Rattus norvegicus

43 known processes

Lama2

laminin, alpha 2

Lama2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to growth factor GO:0070848 189 0.236
cellular component biogenesis GO:0044085 368 0.236
Rat
peptidyl amino acid modification GO:0018193 126 0.187
protein complex biogenesis GO:0070271 263 0.185
cellular component assembly GO:0022607 360 0.177
Rat
glomerulus morphogenesis GO:0072102 1 0.171
cellular response to endogenous stimulus GO:0071495 377 0.150
locomotion GO:0040011 237 0.143
response to peptide hormone GO:0043434 278 0.114
protein complex subunit organization GO:0071822 302 0.114
reproductive process GO:0022414 372 0.113
pro t cell differentiation GO:0002572 1 0.102
organic acid metabolic process GO:0006082 292 0.098
oxoacid metabolic process GO:0043436 290 0.098
cellular response to organonitrogen compound GO:0071417 197 0.095
macromolecular complex subunit organization GO:0043933 339 0.093
macromolecular complex assembly GO:0065003 273 0.087
response to purine containing compound GO:0014074 126 0.084
ion transmembrane transport GO:0034220 365 0.082
leydig cell differentiation GO:0033327 8 0.078
response to acid chemical GO:0001101 222 0.070
negative regulation of multicellular organismal process GO:0051241 203 0.070
protein oligomerization GO:0051259 191 0.069
cellular metal ion homeostasis GO:0006875 172 0.069
single organism reproductive process GO:0044702 297 0.067
blood circulation GO:0008015 183 0.066
response to peptide GO:1901652 292 0.065
carboxylic acid metabolic process GO:0019752 289 0.065
lipid metabolic process GO:0006629 283 0.064
cellular response to peptide GO:1901653 133 0.064
protein phosphorylation GO:0006468 345 0.062
head development GO:0060322 247 0.061
inorganic cation transmembrane transport GO:0098662 202 0.061
positive regulation of multicellular organismal process GO:0051240 387 0.061
cation transmembrane transport GO:0098655 263 0.059
positive regulation of phosphate metabolic process GO:0045937 262 0.058
cell adhesion GO:0007155 110 0.058
Rat
positive regulation of signal transduction GO:0009967 175 0.057
response to radiation GO:0009314 137 0.057
cellular amino acid metabolic process GO:0006520 107 0.056
regulation of protein kinase activity GO:0045859 105 0.056
muscle structure development GO:0061061 87 0.055
positive regulation of cell communication GO:0010647 271 0.054
regulation of cellular amine metabolic process GO:0033238 8 0.052
regulation of protein metabolic process GO:0051246 289 0.052
regulation of hormone levels GO:0010817 187 0.052
cellular ion homeostasis GO:0006873 184 0.051
transmembrane transport GO:0055085 412 0.050
cellular lipid metabolic process GO:0044255 208 0.050
cellular response to oxygen containing compound GO:1901701 386 0.049
kidney development GO:0001822 67 0.049
cellular response to growth factor stimulus GO:0071363 162 0.049
positive regulation of response to stimulus GO:0048584 285 0.049
digestive system development GO:0055123 41 0.048
digestive tract development GO:0048565 39 0.048
signal transduction by phosphorylation GO:0023014 144 0.048
cellular response to nitrogen compound GO:1901699 210 0.048
response to corticosteroid GO:0031960 235 0.047
homeostatic process GO:0042592 331 0.046
response to monosaccharide GO:0034284 159 0.046
regulation of multicellular organismal development GO:2000026 376 0.045
negative regulation of developmental process GO:0051093 125 0.044
response to camp GO:0051591 91 0.044
amine metabolic process GO:0009308 38 0.044
regulation of molecular function GO:0065009 398 0.043
peptidyl tyrosine modification GO:0018212 72 0.043
metanephric comma shaped body morphogenesis GO:0072278 2 0.042
aging GO:0007568 241 0.042
response to oxygen levels GO:0070482 265 0.042
response to organophosphorus GO:0046683 102 0.041
regulation of cellular component movement GO:0051270 150 0.040
regulation of phosphate metabolic process GO:0019220 349 0.039
secretion by cell GO:0032940 248 0.039
secretion GO:0046903 307 0.039
response to mechanical stimulus GO:0009612 134 0.039
brain development GO:0007420 247 0.039
positive regulation of kinase activity GO:0033674 77 0.039
response to carbohydrate GO:0009743 183 0.038
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.038
positive regulation of cell migration GO:0030335 96 0.038
inorganic ion transmembrane transport GO:0098660 229 0.038
cell migration involved in kidney development GO:0035787 2 0.038
cellular chemical homeostasis GO:0055082 247 0.037
negative regulation of b cell differentiation GO:0045578 1 0.037
cellular homeostasis GO:0019725 252 0.037
response to amino acid GO:0043200 75 0.036
immune system process GO:0002376 204 0.036
response to biotic stimulus GO:0009607 226 0.036
cellular response to hormone stimulus GO:0032870 247 0.036
response to glucocorticoid GO:0051384 223 0.035
regulation of protein phosphorylation GO:0001932 183 0.035
peptide cross linking GO:0018149 1 0.035
response to nutrient levels GO:0031667 370 0.034
multicellular organism reproduction GO:0032504 233 0.034
cellular divalent inorganic cation homeostasis GO:0072503 162 0.034
growth GO:0040007 165 0.034
regulation of protein modification process GO:0031399 194 0.034
intracellular signal transduction GO:0035556 314 0.034
cellular response to organic cyclic compound GO:0071407 202 0.034
chemical homeostasis GO:0048878 292 0.033
extracellular fibril organization GO:0043206 1 0.033
organic hydroxy compound metabolic process GO:1901615 115 0.033
regulation of cellular localization GO:0060341 263 0.032
eye morphogenesis GO:0048592 4 0.032
cation homeostasis GO:0055080 195 0.032
positive regulation of transferase activity GO:0051347 81 0.032
regulation of locomotion GO:0040012 148 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
cellular amine metabolic process GO:0044106 38 0.031
positive regulation of protein phosphorylation GO:0001934 135 0.031
heart development GO:0007507 72 0.031
protein complex assembly GO:0006461 263 0.031
protein autophosphorylation GO:0046777 66 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
cellular response to acid chemical GO:0071229 75 0.031
developmental process involved in reproduction GO:0003006 159 0.031
response to glucose GO:0009749 136 0.031
cellular ketone metabolic process GO:0042180 51 0.031
positive regulation of developmental process GO:0051094 283 0.031
response to cytokine GO:0034097 215 0.031
ras protein signal transduction GO:0007265 29 0.031
protein homooligomerization GO:0051260 91 0.031
regulation of b cell differentiation GO:0045577 1 0.030
response to external biotic stimulus GO:0043207 221 0.030
metanephric s shaped body morphogenesis GO:0072284 2 0.030
cytosolic calcium ion homeostasis GO:0051480 140 0.030
myeloid progenitor cell differentiation GO:0002318 1 0.030
regulation of transferase activity GO:0051338 123 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.029
cellular hormone metabolic process GO:0034754 49 0.029
calcium ion homeostasis GO:0055074 162 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
circulatory system process GO:0003013 183 0.029
cellular response to peptide hormone stimulus GO:0071375 120 0.029
positive regulation of phosphorus metabolic process GO:0010562 262 0.029
single organism biosynthetic process GO:0044711 342 0.029
spindle organization GO:0007051 2 0.029
metal ion transport GO:0030001 289 0.028
response to lipopolysaccharide GO:0032496 191 0.028
regulation of cell motility GO:2000145 131 0.028
regulation of cell differentiation GO:0045595 320 0.028
s shaped body morphogenesis GO:0072050 2 0.028
tissue development GO:0009888 252 0.028
vascular endothelial growth factor receptor signaling pathway GO:0048010 8 0.028
cellular cation homeostasis GO:0030003 180 0.028
lymphoid progenitor cell differentiation GO:0002320 2 0.028
ion homeostasis GO:0050801 212 0.028
skin morphogenesis GO:0043589 2 0.027
gastrulation GO:0007369 2 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
cell motility GO:0048870 202 0.027
positive regulation of protein modification process GO:0031401 142 0.027
growth plate cartilage development GO:0003417 2 0.027
regulation of signal transduction GO:0009966 318 0.027
regulation of phosphorylation GO:0042325 248 0.027
multi organism reproductive process GO:0044703 262 0.027
multi multicellular organism process GO:0044706 138 0.027
nitrogen compound transport GO:0071705 229 0.026
regulation of metal ion transport GO:0010959 118 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
cell migration GO:0016477 197 0.025
regulation of nervous system development GO:0051960 264 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
regulation of system process GO:0044057 208 0.025
regulation of membrane repolarization GO:0060306 1 0.025
regulation of canonical wnt signaling pathway GO:0060828 4 0.025
response to alkaloid GO:0043279 132 0.025
cellular polysaccharide metabolic process GO:0044264 23 0.025
regulation of mapk cascade GO:0043408 116 0.024
response to vitamin GO:0033273 131 0.024
response to wounding GO:0009611 254 0.024
cellular response to vitamin e GO:0071306 3 0.024
response to hyperoxia GO:0055093 45 0.024
central nervous system development GO:0007417 311 0.024
regulation of secretion by cell GO:1903530 208 0.024
response to inorganic substance GO:0010035 377 0.024
endochondral bone growth GO:0003416 3 0.024
response to decreased oxygen levels GO:0036293 237 0.023
endoplasmic reticulum to cytosol transport GO:1903513 4 0.023
sex differentiation GO:0007548 113 0.023
comma shaped body morphogenesis GO:0072049 2 0.023
cellular component movement GO:0006928 248 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
metal ion homeostasis GO:0055065 186 0.023
positive regulation of locomotion GO:0040017 102 0.023
regulation of cell proliferation GO:0042127 359 0.023
skeletal system development GO:0001501 41 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
regulation of kinase activity GO:0043549 117 0.022
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
response to extracellular stimulus GO:0009991 380 0.022
organelle organization GO:0006996 266 0.022
action potential GO:0001508 54 0.022
macromolecule localization GO:0033036 252 0.022
regulation of transmembrane transport GO:0034762 122 0.022
localization of cell GO:0051674 202 0.021
muscle tissue development GO:0060537 58 0.021
regulation of response to stress GO:0080134 126 0.021
metanephric mesenchymal cell migration GO:0035789 2 0.021
odontogenesis GO:0042476 32 0.021
response to estrogen GO:0043627 232 0.021
cellular response to extracellular stimulus GO:0031668 73 0.021
regeneration GO:0031099 163 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
formation of primary germ layer GO:0001704 1 0.021
cardiovascular system development GO:0072358 134 0.021
positive regulation of signaling GO:0023056 270 0.021
metanephric glomerulus morphogenesis GO:0072275 1 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
single organism catabolic process GO:0044712 283 0.021
negative regulation of transport GO:0051051 136 0.021
regulation of cellular component organization GO:0051128 368 0.020
response to other organism GO:0051707 220 0.020
neuronal action potential GO:0019228 35 0.020
glycosaminoglycan biosynthetic process GO:0006024 4 0.020
regulation of secretion GO:0051046 224 0.020
cation transport GO:0006812 382 0.020
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.020
single organism behavior GO:0044708 130 0.020
regulation of hormone secretion GO:0046883 106 0.020
cellular response to glucocorticoid stimulus GO:0071385 68 0.019
regulation of body fluid levels GO:0050878 90 0.019
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.019
muscle contraction GO:0006936 88 0.019
organ regeneration GO:0031100 101 0.019
rna metabolic process GO:0016070 406 0.019
vasculogenesis GO:0001570 3 0.019
response to transforming growth factor beta GO:0071559 46 0.019
positive regulation of lipid kinase activity GO:0090218 2 0.019
motor neuron axon guidance GO:0008045 1 0.018
multicellular organismal signaling GO:0035637 44 0.018
positive regulation of molecular function GO:0044093 230 0.018
regulation of peptide transport GO:0090087 87 0.018
actin filament based process GO:0030029 86 0.018
regulation of rna metabolic process GO:0051252 391 0.018
regulation of blood pressure GO:0008217 83 0.018
response to hydrogen peroxide GO:0042542 89 0.018
negative regulation of metabolic process GO:0009892 331 0.017
regulation of behavior GO:0050795 61 0.017
cellular carbohydrate metabolic process GO:0044262 72 0.017
reproduction GO:0000003 245 0.017
digestive tract morphogenesis GO:0048546 8 0.017
activation of protein kinase activity GO:0032147 47 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
neuron differentiation GO:0030182 368 0.017
organophosphate metabolic process GO:0019637 370 0.017
mesoderm development GO:0007498 2 0.017
cellular response to external stimulus GO:0071496 118 0.017
renal system development GO:0072001 67 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
carbohydrate metabolic process GO:0005975 130 0.017
telencephalon development GO:0021537 62 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
cellular response to cytokine stimulus GO:0071345 127 0.016
regulation of cell development GO:0060284 263 0.016
glucan biosynthetic process GO:0009250 15 0.016
oxidation reduction process GO:0055114 304 0.016
protein heterooligomerization GO:0051291 89 0.016
neuron development GO:0048666 286 0.016
actin cytoskeleton organization GO:0030036 73 0.016
response to hexose GO:0009746 144 0.016
regulation of epithelial cell proliferation GO:0050678 49 0.016
response to ethanol GO:0045471 162 0.016
neuron projection development GO:0031175 273 0.016
regulation of ion transport GO:0043269 245 0.016
anatomical structure formation involved in morphogenesis GO:0048646 83 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
glomerulus vasculature development GO:0072012 6 0.016
positive regulation of cellular component movement GO:0051272 102 0.015
response to ionizing radiation GO:0010212 59 0.015
synaptic transmission GO:0007268 235 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
rna biosynthetic process GO:0032774 380 0.015
positive regulation of nervous system development GO:0051962 178 0.015
positive regulation of transport GO:0051050 245 0.015
camera type eye morphogenesis GO:0048593 2 0.015
response to nutrient GO:0007584 248 0.015
hormone metabolic process GO:0042445 69 0.015
heterocycle catabolic process GO:0046700 167 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
nucleotide metabolic process GO:0009117 279 0.015
male gonad development GO:0008584 59 0.015
skeletal muscle tissue development GO:0007519 31 0.015
regulation of platelet activation GO:0010543 2 0.015
peptide transport GO:0015833 97 0.015
positive regulation of growth GO:0045927 55 0.015
cardiac myofibril assembly GO:0055003 1 0.015
extracellular matrix organization GO:0030198 13 0.014
striated muscle tissue development GO:0014706 58 0.014
negative regulation of immune system process GO:0002683 39 0.014
regulation of small gtpase mediated signal transduction GO:0051056 48 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
positive regulation of secretion GO:0051047 140 0.014
cellular response to nutrient levels GO:0031669 60 0.014
cellular response to fluoride GO:1902618 1 0.014
response to increased oxygen levels GO:0036296 45 0.014
response to estradiol GO:0032355 164 0.014
regulation of growth GO:0040008 105 0.014
ossification GO:0001503 70 0.014
rhythmic process GO:0048511 156 0.014
regulation of catalytic activity GO:0050790 304 0.014
transmission of nerve impulse GO:0019226 42 0.014
extracellular structure organization GO:0043062 13 0.013
response to temperature stimulus GO:0009266 94 0.013
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
epithelial cell differentiation GO:0030855 71 0.013
cytoskeleton organization GO:0007010 111 0.013
regulation of embryonic development GO:0045995 2 0.013
platelet derived growth factor receptor alpha signaling pathway GO:0035790 1 0.013
regulation of neurogenesis GO:0050767 247 0.013
male gamete generation GO:0048232 99 0.013
response to oxidative stress GO:0006979 186 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
single organism organelle organization GO:1902589 180 0.013
sexual reproduction GO:0019953 148 0.013
calcium ion transport GO:0006816 131 0.013
behavior GO:0007610 205 0.013
response to reactive oxygen species GO:0000302 120 0.013
liver development GO:0001889 90 0.013
immune response GO:0006955 104 0.013
eye development GO:0001654 50 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
response to hypoxia GO:0001666 231 0.013
camera type eye development GO:0043010 48 0.013
gland development GO:0048732 155 0.013
regulation of membrane potential GO:0042391 110 0.013
rho protein signal transduction GO:0007266 11 0.013
endochondral bone morphogenesis GO:0060350 7 0.013
regulation of apoptotic process GO:0042981 335 0.013
cellular catabolic process GO:0044248 295 0.013
circulatory system development GO:0072359 134 0.013
neurological system process GO:0050877 219 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
sensory perception GO:0007600 101 0.012
response to metal ion GO:0010038 253 0.012
chemotaxis GO:0006935 66 0.012
skeletal muscle organ development GO:0060538 33 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
glycogen metabolic process GO:0005977 23 0.012
cellular response to lipid GO:0071396 201 0.012
forebrain development GO:0030900 98 0.012
response to activity GO:0014823 73 0.012
embryonic skeletal system development GO:0048706 3 0.012
non canonical wnt signaling pathway GO:0035567 3 0.012
acute inflammatory response GO:0002526 58 0.012
male sex differentiation GO:0046661 64 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
negative regulation of molecular function GO:0044092 133 0.012
monosaccharide transport GO:0015749 31 0.012
organic substance catabolic process GO:1901575 316 0.012
transcription dna templated GO:0006351 377 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
response to retinoic acid GO:0032526 63 0.012
cellular response to stress GO:0033554 269 0.012
cell projection organization GO:0030030 302 0.012
urogenital system development GO:0001655 78 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
nucleic acid templated transcription GO:0097659 379 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
choline transport GO:0015871 4 0.012
reproductive structure development GO:0048608 128 0.012
amide transport GO:0042886 105 0.012
negative regulation of cell death GO:0060548 229 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
potassium ion transport GO:0006813 97 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
embryo development GO:0009790 49 0.011
glycogen biosynthetic process GO:0005978 15 0.011
regulation of cell migration GO:0030334 128 0.011
catabolic process GO:0009056 351 0.011
hexose transport GO:0008645 29 0.011
response to food GO:0032094 27 0.011
spermatogenesis GO:0007283 99 0.011
response to fluoride GO:1902617 3 0.011
muscle system process GO:0003012 115 0.011
peptide secretion GO:0002790 86 0.011
anion transport GO:0006820 178 0.011
signal release GO:0023061 145 0.011
cellular component morphogenesis GO:0032989 155 0.011
kidney mesenchyme development GO:0072074 2 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.011
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.011
response to toxic substance GO:0009636 133 0.011
cell cycle GO:0007049 101 0.011
response to ketone GO:1901654 182 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
taxis GO:0042330 67 0.011
renal system vasculature development GO:0061437 6 0.011
positive regulation of immune system process GO:0002684 90 0.011
blood vessel development GO:0001568 69 0.011
adult locomotory behavior GO:0008344 4 0.011
gamete generation GO:0007276 124 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of cell projection organization GO:0031344 175 0.011
cell cell signaling GO:0007267 335 0.011
regulation of immune system process GO:0002682 123 0.010
heart morphogenesis GO:0003007 3 0.010
developmental growth GO:0048589 100 0.010
carbohydrate biosynthetic process GO:0016051 42 0.010
regulation of heart rate GO:0002027 16 0.010
regulation of cell growth GO:0001558 85 0.010
plasma lipoprotein particle clearance GO:0034381 3 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
negative regulation of gene expression GO:0010629 199 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
biological adhesion GO:0022610 110 0.010
Rat
regulation of catabolic process GO:0009894 113 0.010

Lama2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.023
disease of anatomical entity DOID:7 0 0.022
Human
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.018
Human
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.013
myopathy DOID:423 0 0.012
Human
muscular disease DOID:0080000 0 0.012
Human
muscular dystrophy DOID:9884 0 0.012
Human
muscle tissue disease DOID:66 0 0.012
Human
artery disease DOID:0050828 0 0.011
vascular disease DOID:178 0 0.011
cardiovascular system disease DOID:1287 0 0.011
gastrointestinal system cancer DOID:3119 0 0.010