Rattus norvegicus

94 known processes

Ldha

lactate dehydrogenase A

(Aliases: Ldh1)

Ldha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate catabolic process GO:0016052 40 0.999
single organism carbohydrate catabolic process GO:0044724 40 0.997
glucose metabolic process GO:0006006 52 0.931
monocarboxylic acid metabolic process GO:0032787 152 0.885
pyruvate metabolic process GO:0006090 27 0.840
hexose biosynthetic process GO:0019319 15 0.808
glycolytic process GO:0006096 17 0.795
hexose metabolic process GO:0019318 58 0.788
organic substance catabolic process GO:1901575 316 0.786
gluconeogenesis GO:0006094 15 0.733
organic acid metabolic process GO:0006082 292 0.713
catabolic process GO:0009056 351 0.706
single organism carbohydrate metabolic process GO:0044723 118 0.647
carboxylic acid metabolic process GO:0019752 289 0.643
monosaccharide metabolic process GO:0005996 61 0.628
carbohydrate metabolic process GO:0005975 130 0.573
single organism biosynthetic process GO:0044711 342 0.548
single organism catabolic process GO:0044712 283 0.543
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.394
regulation of transcription dna templated GO:0006355 374 0.351
monosaccharide biosynthetic process GO:0046364 16 0.340
regulation of cellular component organization GO:0051128 368 0.336
negative regulation of biosynthetic process GO:0009890 168 0.315
negative regulation of cellular metabolic process GO:0031324 281 0.311
response to decreased oxygen levels GO:0036293 237 0.266
regulation of apoptotic process GO:0042981 335 0.263
generation of precursor metabolites and energy GO:0006091 62 0.263
carbohydrate derivative biosynthetic process GO:1901137 124 0.223
purine nucleoside biosynthetic process GO:0042451 21 0.223
rna metabolic process GO:0016070 406 0.217
regeneration GO:0031099 163 0.213
oxoacid metabolic process GO:0043436 290 0.212
cellular response to oxygen containing compound GO:1901701 386 0.205
ribose phosphate biosynthetic process GO:0046390 87 0.204
negative regulation of metabolic process GO:0009892 331 0.178
response to peptide hormone GO:0043434 278 0.176
carbohydrate biosynthetic process GO:0016051 42 0.168
regulation of nucleic acid templated transcription GO:1903506 380 0.167
purine ribonucleoside biosynthetic process GO:0046129 21 0.165
purine nucleoside monophosphate metabolic process GO:0009126 84 0.161
nucleotide biosynthetic process GO:0009165 98 0.159
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.150
purine nucleotide biosynthetic process GO:0006164 83 0.147
response to bacterium GO:0009617 200 0.145
cellular component assembly GO:0022607 360 0.144
single organism organelle organization GO:1902589 180 0.143
purine ribonucleotide metabolic process GO:0009150 227 0.139
cellular response to peptide hormone stimulus GO:0071375 120 0.137
hepaticobiliary system development GO:0061008 90 0.137
nucleobase containing small molecule metabolic process GO:0055086 316 0.136
purine ribonucleoside metabolic process GO:0046128 168 0.134
organelle organization GO:0006996 266 0.132
gland development GO:0048732 155 0.128
ribonucleoside biosynthetic process GO:0042455 25 0.127
negative regulation of rna biosynthetic process GO:1902679 118 0.125
programmed cell death GO:0012501 392 0.123
regulation of rna metabolic process GO:0051252 391 0.123
regulation of cell differentiation GO:0045595 320 0.119
response to starvation GO:0042594 59 0.118
membrane organization GO:0061024 94 0.116
response to estrogen GO:0043627 232 0.115
transcription dna templated GO:0006351 377 0.114
purine ribonucleoside monophosphate biosynthetic process GO:0009168 20 0.109
response to wounding GO:0009611 254 0.109
cellular response to endogenous stimulus GO:0071495 377 0.108
negative regulation of rna metabolic process GO:0051253 123 0.105
tissue development GO:0009888 252 0.104
negative regulation of gene expression GO:0010629 199 0.102
proteolysis GO:0006508 175 0.101
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.098
nucleic acid templated transcription GO:0097659 379 0.098
positive regulation of phosphorus metabolic process GO:0010562 262 0.096
apoptotic process GO:0006915 381 0.095
cellular response to peptide GO:1901653 133 0.094
purine ribonucleotide biosynthetic process GO:0009152 81 0.092
liver development GO:0001889 90 0.091
response to purine containing compound GO:0014074 126 0.087
response to nutrient GO:0007584 248 0.085
cellular response to insulin stimulus GO:0032869 81 0.085
negative regulation of macromolecule metabolic process GO:0010605 260 0.083
purine nucleoside triphosphate metabolic process GO:0009144 141 0.083
response to camp GO:0051591 91 0.083
response to oxygen levels GO:0070482 265 0.083
cellular cation homeostasis GO:0030003 180 0.083
carbohydrate derivative metabolic process GO:1901135 346 0.081
macromolecular complex assembly GO:0065003 273 0.079
negative regulation of cell death GO:0060548 229 0.079
regulation of multicellular organismal development GO:2000026 376 0.079
single organism membrane organization GO:0044802 74 0.079
organophosphate metabolic process GO:0019637 370 0.076
positive regulation of biosynthetic process GO:0009891 319 0.075
protein nitrosylation GO:0017014 2 0.075
purine nucleotide metabolic process GO:0006163 229 0.075
negative regulation of transcription dna templated GO:0045892 116 0.075
negative regulation of nucleic acid templated transcription GO:1903507 117 0.074
rna biosynthetic process GO:0032774 380 0.074
response to hypoxia GO:0001666 231 0.074
ribonucleoside triphosphate metabolic process GO:0009199 141 0.073
organ regeneration GO:0031100 101 0.073
cellular response to hormone stimulus GO:0032870 247 0.073
response to estradiol GO:0032355 164 0.069
nucleoside triphosphate biosynthetic process GO:0009142 8 0.069
regulation of neuron differentiation GO:0045664 208 0.068
spermatogenesis GO:0007283 99 0.067
regulation of molecular function GO:0065009 398 0.067
reproductive process GO:0022414 372 0.067
regulation of rna biosynthetic process GO:2001141 381 0.067
adp metabolic process GO:0046031 8 0.066
response to extracellular stimulus GO:0009991 380 0.066
cellular ion homeostasis GO:0006873 184 0.066
response to cytokine GO:0034097 215 0.065
tissue regeneration GO:0042246 36 0.065
purine containing compound biosynthetic process GO:0072522 85 0.063
positive regulation of cellular component organization GO:0051130 200 0.061
response to nutrient levels GO:0031667 370 0.061
response to insulin GO:0032868 133 0.061
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.061
positive regulation of cell differentiation GO:0045597 217 0.059
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.057
cellular component biogenesis GO:0044085 368 0.057
response to lipopolysaccharide GO:0032496 191 0.056
ribonucleotide biosynthetic process GO:0009260 85 0.056
regulation of organelle organization GO:0033043 80 0.056
mitotic dna damage checkpoint GO:0044773 1 0.054
homeostatic process GO:0042592 331 0.054
ribonucleotide metabolic process GO:0009259 231 0.054
cellular response to organonitrogen compound GO:0071417 197 0.054
regulation of catalytic activity GO:0050790 304 0.052
cation homeostasis GO:0055080 195 0.052
response to glucocorticoid GO:0051384 223 0.050
single organism reproductive process GO:0044702 297 0.048
ribonucleoside triphosphate biosynthetic process GO:0009201 7 0.048
positive regulation of cellular biosynthetic process GO:0031328 295 0.048
response to metal ion GO:0010038 253 0.047
organophosphate biosynthetic process GO:0090407 143 0.046
ribose phosphate metabolic process GO:0019693 235 0.046
metal ion transport GO:0030001 289 0.045
chemical homeostasis GO:0048878 292 0.044
regulation of programmed cell death GO:0043067 341 0.044
cellular chemical homeostasis GO:0055082 247 0.044
developmental growth GO:0048589 100 0.044
nucleoside biosynthetic process GO:0009163 25 0.044
cellular response to nitrogen compound GO:1901699 210 0.044
regulation of nervous system development GO:0051960 264 0.044
wound healing GO:0042060 122 0.043
reproduction GO:0000003 245 0.043
anatomical structure morphogenesis GO:0009653 298 0.043
Fly
response to corticosteroid GO:0031960 235 0.043
nucleoside phosphate metabolic process GO:0006753 283 0.042
transmembrane transport GO:0055085 412 0.042
neurotransmitter uptake GO:0001504 3 0.042
aging GO:0007568 241 0.042
protein complex biogenesis GO:0070271 263 0.041
response to acid chemical GO:0001101 222 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.041
multi organism reproductive process GO:0044703 262 0.041
negative regulation of cellular biosynthetic process GO:0031327 161 0.041
cell type specific apoptotic process GO:0097285 134 0.040
cellular ketone metabolic process GO:0042180 51 0.040
cation transmembrane transport GO:0098655 263 0.039
multicellular organismal reproductive process GO:0048609 233 0.039
purine nucleoside diphosphate metabolic process GO:0009135 9 0.039
regulation of cell growth GO:0001558 85 0.039
synaptic transmission GO:0007268 235 0.038
response to other organism GO:0051707 220 0.038
regulation of neurogenesis GO:0050767 247 0.038
protein complex subunit organization GO:0071822 302 0.038
response to peptide GO:1901652 292 0.038
nucleoside phosphate catabolic process GO:1901292 140 0.038
negative regulation of cellular component organization GO:0051129 83 0.037
male gamete generation GO:0048232 99 0.037
cellular homeostasis GO:0019725 252 0.036
regulation of cell development GO:0060284 263 0.036
growth GO:0040007 165 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.035
single organism behavior GO:0044708 130 0.035
ion transmembrane transport GO:0034220 365 0.035
neuron differentiation GO:0030182 368 0.034
cellular catabolic process GO:0044248 295 0.034
regulation of cell proliferation GO:0042127 359 0.034
protein complex assembly GO:0006461 263 0.033
regulation of immune system process GO:0002682 123 0.033
response to biotic stimulus GO:0009607 226 0.033
negative regulation of programmed cell death GO:0043069 183 0.032
skeletal muscle tissue regeneration GO:0043403 10 0.032
cellular response to stress GO:0033554 269 0.032
lipid metabolic process GO:0006629 283 0.032
regulation of hydrolase activity GO:0051336 143 0.031
coenzyme metabolic process GO:0006732 86 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
neuron death GO:0070997 127 0.031
nucleoside metabolic process GO:0009116 179 0.031
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.031
cell cell signaling GO:0007267 335 0.030
negative regulation of cell communication GO:0010648 158 0.030
behavior GO:0007610 205 0.030
response to external biotic stimulus GO:0043207 221 0.030
multicellular organism reproduction GO:0032504 233 0.030
neuron projection development GO:0031175 273 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
positive regulation of transport GO:0051050 245 0.029
response to transition metal nanoparticle GO:1990267 122 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
response to inorganic substance GO:0010035 377 0.028
divalent inorganic cation homeostasis GO:0072507 165 0.028
receptor mediated endocytosis GO:0006898 42 0.028
carboxylic acid biosynthetic process GO:0046394 83 0.027
nucleoside monophosphate metabolic process GO:0009123 93 0.027
regulation of neuron projection development GO:0010975 161 0.027
cation transport GO:0006812 382 0.027
calcium ion homeostasis GO:0055074 162 0.026
nucleoside triphosphate metabolic process GO:0009141 144 0.026
cell cycle checkpoint GO:0000075 2 0.026
regulation of ion transport GO:0043269 245 0.026
response to atp GO:0033198 13 0.026
carbohydrate derivative catabolic process GO:1901136 147 0.026
response to hexose GO:0009746 144 0.025
regulation of cellular localization GO:0060341 263 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
ribonucleoside monophosphate metabolic process GO:0009161 88 0.024
immune system process GO:0002376 204 0.024
monovalent inorganic cation transport GO:0015672 172 0.024
cellular amine metabolic process GO:0044106 38 0.024
ion homeostasis GO:0050801 212 0.024
sexual reproduction GO:0019953 148 0.024
nucleoside diphosphate metabolic process GO:0009132 14 0.024
developmental process involved in reproduction GO:0003006 159 0.024
nucleoside phosphate biosynthetic process GO:1901293 102 0.024
regulation of nucleotide metabolic process GO:0006140 117 0.024
cytoskeleton organization GO:0007010 111 0.024
organonitrogen compound biosynthetic process GO:1901566 167 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.023
cellular carbohydrate metabolic process GO:0044262 72 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
ribonucleoside monophosphate biosynthetic process GO:0009156 24 0.023
metal ion homeostasis GO:0055065 186 0.023
response to monosaccharide GO:0034284 159 0.023
response to carbohydrate GO:0009743 183 0.022
nitrogen compound transport GO:0071705 229 0.022
cellular protein catabolic process GO:0044257 19 0.022
regulation of atp biosynthetic process GO:2001169 2 0.022
camp metabolic process GO:0046058 63 0.022
negative regulation of transport GO:0051051 136 0.022
regulation of protein metabolic process GO:0051246 289 0.022
negative regulation of response to stimulus GO:0048585 155 0.022
locomotion GO:0040011 237 0.022
regulation of carbohydrate metabolic process GO:0006109 41 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
central nervous system development GO:0007417 311 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
negative regulation of cellular protein metabolic process GO:0032269 106 0.021
inorganic ion transmembrane transport GO:0098660 229 0.020
organic acid transport GO:0015849 116 0.020
ribonucleotide catabolic process GO:0009261 136 0.020
response to glucose GO:0009749 136 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
nucleoside catabolic process GO:0009164 126 0.020
atp metabolic process GO:0046034 72 0.020
cell migration GO:0016477 197 0.020
protein homooligomerization GO:0051260 91 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
localization of cell GO:0051674 202 0.019
cell projection organization GO:0030030 302 0.019
carboxylic acid transport GO:0046942 115 0.019
negative regulation of neuron death GO:1901215 69 0.019
purine ribonucleoside diphosphate metabolic process GO:0009179 9 0.019
regulation of signal transduction GO:0009966 318 0.019
mitochondrion organization GO:0007005 35 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
positive regulation of cellular component biogenesis GO:0044089 55 0.018
response to temperature stimulus GO:0009266 94 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
regulation of membrane potential GO:0042391 110 0.018
neuron development GO:0048666 286 0.018
positive regulation of cell development GO:0010720 176 0.018
purine nucleoside catabolic process GO:0006152 124 0.018
aldehyde biosynthetic process GO:0046184 4 0.018
response to ketone GO:1901654 182 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
ubiquitin dependent protein catabolic process GO:0006511 14 0.017
neurological system process GO:0050877 219 0.017
cellular lipid metabolic process GO:0044255 208 0.017
regulation of cell cycle process GO:0010564 31 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
small molecule biosynthetic process GO:0044283 124 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.017
positive regulation of developmental process GO:0051094 283 0.017
purine containing compound catabolic process GO:0072523 138 0.017
cell cell signaling involved in cell fate commitment GO:0045168 2 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
mitotic spindle organization GO:0007052 2 0.016
gamete generation GO:0007276 124 0.016
heart morphogenesis GO:0003007 3 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
extracellular matrix constituent secretion GO:0070278 4 0.016
cell cycle GO:0007049 101 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
chromosome segregation GO:0007059 2 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
brain development GO:0007420 247 0.015
secretion by cell GO:0032940 248 0.015
mitotic cell cycle GO:0000278 49 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
organelle fusion GO:0048284 17 0.015
adp biosynthetic process GO:0006172 8 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
regulation of hormone levels GO:0010817 187 0.015
cofactor biosynthetic process GO:0051188 28 0.015
eye morphogenesis GO:0048592 4 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.015
cell adhesion GO:0007155 110 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
macromolecule localization GO:0033036 252 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
response to organophosphorus GO:0046683 102 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
regulation of synaptic transmission GO:0050804 141 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
cell motility GO:0048870 202 0.014
purine nucleoside triphosphate biosynthetic process GO:0009145 6 0.014
response to alkaloid GO:0043279 132 0.014
regulation of catabolic process GO:0009894 113 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
negative regulation of signal transduction GO:0009968 83 0.014
nucleotide catabolic process GO:0009166 139 0.014
regulation of lipid metabolic process GO:0019216 68 0.014
apoptotic signaling pathway GO:0097190 27 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
single organism membrane fusion GO:0044801 17 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
nucleotide metabolic process GO:0009117 279 0.013
atp catabolic process GO:0006200 54 0.013
peptidyl amino acid modification GO:0018193 126 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
regulation of growth GO:0040008 105 0.013
cell growth GO:0016049 104 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
vesicle mediated transport GO:0016192 181 0.013
positive regulation of protein metabolic process GO:0051247 178 0.012
response to growth factor GO:0070848 189 0.012
secretion GO:0046903 307 0.012
purine containing compound metabolic process GO:0072521 253 0.012
negative regulation of nervous system development GO:0051961 79 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
cofactor metabolic process GO:0051186 95 0.012
regulation of nucleotide biosynthetic process GO:0030808 47 0.012
brain renin angiotensin system GO:0002035 3 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
purine ribonucleoside diphosphate biosynthetic process GO:0009180 9 0.012
tricarboxylic acid metabolic process GO:0072350 10 0.012
response to ammonium ion GO:0060359 71 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
glycosyl compound biosynthetic process GO:1901659 25 0.011
protein phosphorylation GO:0006468 345 0.011
second messenger mediated signaling GO:0019932 51 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
heme biosynthetic process GO:0006783 4 0.011
protein catabolic process GO:0030163 30 0.011
blood circulation GO:0008015 183 0.011
regulation of cell projection organization GO:0031344 175 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
regulation of cysteine type endopeptidase activity GO:2000116 32 0.011
intracellular transport GO:0046907 185 0.011
lipid storage GO:0019915 1 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
cellular component movement GO:0006928 248 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
protein oligomerization GO:0051259 191 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
regulation of potassium ion transport GO:0043266 29 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
negative regulation of cell development GO:0010721 82 0.011
positive regulation of molecular function GO:0044093 230 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
g2 dna damage checkpoint GO:0031572 1 0.011
response to oxidative stress GO:0006979 186 0.011
positive regulation of gene expression GO:0010628 244 0.011
divalent inorganic cation transport GO:0072511 134 0.011
circulatory system development GO:0072359 134 0.011
alpha amino acid metabolic process GO:1901605 71 0.011
regulation of metal ion transport GO:0010959 118 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
purine nucleoside monophosphate catabolic process GO:0009128 55 0.010
biological adhesion GO:0022610 110 0.010
dicarboxylic acid metabolic process GO:0043648 42 0.010
camera type eye morphogenesis GO:0048593 2 0.010
regulation of transmembrane transport GO:0034762 122 0.010
energy derivation by oxidation of organic compounds GO:0015980 46 0.010
peptidyl cysteine s nitrosylation GO:0018119 2 0.010
immune system development GO:0002520 41 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.010

Ldha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.011
disease of anatomical entity DOID:7 0 0.011