Rattus norvegicus

33 known processes

Lef1

lymphoid enhancer binding factor 1

Lef1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic appendage morphogenesis GO:0035113 4 0.356
Mouse
appendage morphogenesis GO:0035107 4 0.287
Mouse
regulation of apoptotic process GO:0042981 335 0.236
Human
skeletal system development GO:0001501 41 0.192
leukocyte activation GO:0045321 76 0.179
Mouse
gland development GO:0048732 155 0.175
Mouse
limb morphogenesis GO:0035108 4 0.174
Mouse
negative regulation of metabolic process GO:0009892 331 0.169
Human Mouse
anatomical structure morphogenesis GO:0009653 298 0.168
Human Mouse
transcription dna templated GO:0006351 377 0.161
Human Mouse
cell migration GO:0016477 197 0.159
Human Mouse
cellular response to lipid GO:0071396 201 0.139
Human
regulation of transcription dna templated GO:0006355 374 0.135
Human Mouse
immune system process GO:0002376 204 0.122
Human Mouse
apoptotic process GO:0006915 381 0.114
Human Mouse
regulation of leukocyte activation GO:0002694 45 0.112
cellular response to peptide hormone stimulus GO:0071375 120 0.111
response to lipopolysaccharide GO:0032496 191 0.109
cell motility GO:0048870 202 0.107
Human Mouse
positive regulation of immune system process GO:0002684 90 0.106
Human
neuron projection development GO:0031175 273 0.105
nucleic acid templated transcription GO:0097659 379 0.103
Human Mouse
organic acid metabolic process GO:0006082 292 0.101
response to peptide GO:1901652 292 0.098
biological adhesion GO:0022610 110 0.090
taxis GO:0042330 67 0.090
Human
regulation of cellular component movement GO:0051270 150 0.084
Human
rna biosynthetic process GO:0032774 380 0.084
Human Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.082
Human Mouse
programmed cell death GO:0012501 392 0.082
Human Mouse
embryonic skeletal system development GO:0048706 3 0.079
response to oxygen levels GO:0070482 265 0.078
neuron differentiation GO:0030182 368 0.078
organ morphogenesis GO:0009887 75 0.078
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.078
Human Mouse
negative regulation of cell proliferation GO:0008285 119 0.077
neuron development GO:0048666 286 0.076
rna metabolic process GO:0016070 406 0.076
Human Mouse
locomotion GO:0040011 237 0.074
Human Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.074
Human Mouse
regulation of immune system process GO:0002682 123 0.073
Human
liver development GO:0001889 90 0.072
cellular component movement GO:0006928 248 0.072
Human Mouse
regulation of signal transduction GO:0009966 318 0.068
Human Mouse
positive regulation of protein modification process GO:0031401 142 0.067
positive regulation of cell motility GO:2000147 97 0.066
Human
embryonic skeletal system morphogenesis GO:0048704 3 0.063
oxoacid metabolic process GO:0043436 290 0.062
macromolecule localization GO:0033036 252 0.062
negative regulation of multicellular organismal process GO:0051241 203 0.061
Human Mouse
cellular response to oxygen containing compound GO:1901701 386 0.060
response to insulin GO:0032868 133 0.059
regulation of phosphorylation GO:0042325 248 0.058
regulation of phosphate metabolic process GO:0019220 349 0.057
regulation of protein kinase activity GO:0045859 105 0.057
negative regulation of rna biosynthetic process GO:1902679 118 0.057
Human Mouse
negative regulation of rna metabolic process GO:0051253 123 0.057
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 197 0.057
Human Mouse
cell adhesion GO:0007155 110 0.056
negative regulation of biosynthetic process GO:0009890 168 0.056
Human Mouse
response to extracellular stimulus GO:0009991 380 0.056
hepaticobiliary system development GO:0061008 90 0.056
response to molecule of bacterial origin GO:0002237 194 0.055
regulation of cell differentiation GO:0045595 320 0.055
Human
cellular response to organonitrogen compound GO:0071417 197 0.055
cell morphogenesis GO:0000902 142 0.053
Human Mouse
cell projection organization GO:0030030 302 0.053
response to increased oxygen levels GO:0036296 45 0.053
negative regulation of developmental process GO:0051093 125 0.052
Mouse
anterior posterior pattern specification GO:0009952 1 0.052
Mouse
gliogenesis GO:0042063 93 0.052
Mouse
response to oxidative stress GO:0006979 186 0.052
positive regulation of cell proliferation GO:0008284 249 0.052
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.051
Human Mouse
embryonic hindlimb morphogenesis GO:0035116 2 0.051
regulation of cell migration GO:0030334 128 0.050
Human
axonogenesis GO:0007409 71 0.050
cellular response to hormone stimulus GO:0032870 247 0.048
Human
carboxylic acid metabolic process GO:0019752 289 0.048
cellular response to stress GO:0033554 269 0.047
lymphocyte activation GO:0046649 43 0.047
Mouse
cellular macromolecule localization GO:0070727 122 0.047
regulation of rna biosynthetic process GO:2001141 381 0.047
Human Mouse
regulation of secretion GO:0051046 224 0.046
response to external biotic stimulus GO:0043207 221 0.046
hormone transport GO:0009914 121 0.045
positive regulation of rna metabolic process GO:0051254 203 0.045
Human Mouse
regulation of mesenchymal cell proliferation GO:0010464 4 0.045
tissue development GO:0009888 252 0.045
response to peptide hormone GO:0043434 278 0.044
cell part morphogenesis GO:0032990 123 0.044
mononuclear cell proliferation GO:0032943 29 0.044
Mouse
regulation of cell activation GO:0050865 50 0.044
positive regulation of cellular biosynthetic process GO:0031328 295 0.043
Human Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.043
Human Mouse
skeletal system morphogenesis GO:0048705 12 0.042
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
Human Mouse
catabolic process GO:0009056 351 0.041
negative regulation of cell death GO:0060548 229 0.041
Human
regulation of nucleic acid templated transcription GO:1903506 380 0.041
Human Mouse
cellular protein localization GO:0034613 122 0.041
cell activation GO:0001775 97 0.040
Mouse
cellular lipid metabolic process GO:0044255 208 0.040
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.040
Human Mouse
embryonic limb morphogenesis GO:0030326 4 0.040
Mouse
neuron projection morphogenesis GO:0048812 122 0.039
response to nutrient levels GO:0031667 370 0.039
negative regulation of cellular biosynthetic process GO:0031327 161 0.039
Human Mouse
regulation of hormone levels GO:0010817 187 0.039
negative regulation of apoptotic process GO:0043066 181 0.038
Human
positive regulation of catalytic activity GO:0043085 184 0.038
cell morphogenesis involved in differentiation GO:0000904 119 0.038
Human Mouse
neuron fate commitment GO:0048663 4 0.038
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.037
amine metabolic process GO:0009308 38 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
response to hyperoxia GO:0055093 45 0.037
regulation of multicellular organismal development GO:2000026 376 0.036
Human Mouse
regulation of rna metabolic process GO:0051252 391 0.036
Human Mouse
embryonic cranial skeleton morphogenesis GO:0048701 2 0.036
axon development GO:0061564 96 0.035
mesenchymal cell proliferation GO:0010463 4 0.035
regeneration GO:0031099 163 0.035
response to other organism GO:0051707 220 0.035
positive regulation of cellular component movement GO:0051272 102 0.035
Human
regulation of programmed cell death GO:0043067 341 0.035
Human
negative regulation of response to stimulus GO:0048585 155 0.035
Human
urogenital system development GO:0001655 78 0.034
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.034
Mouse
negative regulation of nervous system development GO:0051961 79 0.033
positive regulation of cell death GO:0010942 184 0.033
regulation of epithelial cell proliferation GO:0050678 49 0.033
regulation of response to stress GO:0080134 126 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
response to organophosphorus GO:0046683 102 0.032
response to growth factor GO:0070848 189 0.032
positive regulation of programmed cell death GO:0043068 157 0.032
single organism cell adhesion GO:0098602 46 0.032
Human Mouse
protein phosphorylation GO:0006468 345 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
lipid metabolic process GO:0006629 283 0.030
regulation of leukocyte proliferation GO:0070663 26 0.030
negative regulation of nucleic acid templated transcription GO:1903507 117 0.029
Human Mouse
bone development GO:0060348 25 0.029
positive regulation of protein phosphorylation GO:0001934 135 0.029
regulation of mononuclear cell proliferation GO:0032944 26 0.029
organic acid transport GO:0015849 116 0.029
regulation of intracellular signal transduction GO:1902531 218 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.029
Human
head development GO:0060322 247 0.028
Mouse
regulation of cell motility GO:2000145 131 0.028
Human
negative regulation of transport GO:0051051 136 0.028
regulation of anatomical structure morphogenesis GO:0022603 141 0.028
Human
negative regulation of cell development GO:0010721 82 0.028
immune system development GO:0002520 41 0.027
Human Mouse
cardiovascular system development GO:0072358 134 0.027
Mouse
cellular component morphogenesis GO:0032989 155 0.027
Human Mouse
cell projection morphogenesis GO:0048858 123 0.027
regulation of anatomical structure size GO:0090066 135 0.027
regulation of secretion by cell GO:1903530 208 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
Human
cellular response to oxidative stress GO:0034599 76 0.027
regulation of neuron differentiation GO:0045664 208 0.027
response to wounding GO:0009611 254 0.027
response to hypoxia GO:0001666 231 0.026
cellular ketone metabolic process GO:0042180 51 0.026
negative regulation of gene expression GO:0010629 199 0.026
Human Mouse
tissue remodeling GO:0048771 40 0.026
action potential GO:0001508 54 0.026
cell type specific apoptotic process GO:0097285 134 0.026
Human
response to bacterium GO:0009617 200 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
Human Mouse
chemotaxis GO:0006935 66 0.026
Human
cellular response to cytokine stimulus GO:0071345 127 0.026
Human
response to ketone GO:1901654 182 0.026
regulation of cell proliferation GO:0042127 359 0.026
Human
positive regulation of rna biosynthetic process GO:1902680 197 0.026
Human Mouse
organic substance catabolic process GO:1901575 316 0.025
positive regulation of gene expression GO:0010628 244 0.025
Human Mouse
cellular amine metabolic process GO:0044106 38 0.025
nitrogen compound transport GO:0071705 229 0.025
metestrus GO:0060210 1 0.025
nephric duct development GO:0072176 1 0.025
cellular catabolic process GO:0044248 295 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
Human Mouse
hindlimb morphogenesis GO:0035137 2 0.025
regulation of protein phosphorylation GO:0001932 183 0.024
cellular response to peptide GO:1901653 133 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
single organismal cell cell adhesion GO:0016337 42 0.024
Human Mouse
regulation of canonical wnt signaling pathway GO:0060828 4 0.024
Human
regulation of establishment of planar polarity GO:0090175 2 0.024
regulation of neuron projection development GO:0010975 161 0.024
regulation of system process GO:0044057 208 0.024
reproductive process GO:0022414 372 0.024
Mouse
regulation of cellular component organization GO:0051128 368 0.024
Human
regulation of nervous system development GO:0051960 264 0.023
hormone metabolic process GO:0042445 69 0.023
positive regulation of protein metabolic process GO:0051247 178 0.023
regulation of cell morphogenesis GO:0022604 77 0.023
Human
regulation of axonogenesis GO:0050770 37 0.023
negative regulation of cell differentiation GO:0045596 99 0.023
single organism organelle organization GO:1902589 180 0.023
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
Human Mouse
regulation of cell projection size GO:0032536 1 0.023
positive regulation of biosynthetic process GO:0009891 319 0.022
Human Mouse
positive regulation of neurogenesis GO:0050769 165 0.022
b cell differentiation GO:0030183 2 0.022
mesoderm development GO:0007498 2 0.022
Mouse
positive regulation of cell communication GO:0010647 271 0.022
regulation of cell projection organization GO:0031344 175 0.022
developmental growth involved in morphogenesis GO:0060560 33 0.022
prostate gland morphogenesis GO:0060512 2 0.021
connective tissue development GO:0061448 33 0.021
single organism catabolic process GO:0044712 283 0.021
lymphocyte proliferation GO:0046651 29 0.021
Mouse
motor neuron axon guidance GO:0008045 1 0.021
response to acid chemical GO:0001101 222 0.021
regulation of locomotion GO:0040012 148 0.021
Human
regulation of lymphocyte proliferation GO:0050670 26 0.021
cellular response to biotic stimulus GO:0071216 59 0.021
tube development GO:0035295 89 0.021
Mouse
reactive oxygen species metabolic process GO:0072593 37 0.021
cell fate determination GO:0001709 2 0.020
response to estrogen GO:0043627 232 0.020
response to decreased oxygen levels GO:0036293 237 0.020
response to retinoic acid GO:0032526 63 0.020
regulation of kinase activity GO:0043549 117 0.020
regulation of protein metabolic process GO:0051246 289 0.020
Human
response to camp GO:0051591 91 0.020
response to purine containing compound GO:0014074 126 0.020
intracellular signal transduction GO:0035556 314 0.020
regulation of neurogenesis GO:0050767 247 0.020
response to cytokine GO:0034097 215 0.020
Human
eye morphogenesis GO:0048592 4 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
Human
muscle system process GO:0003012 115 0.020
response to corticosteroid GO:0031960 235 0.020
neuronal action potential GO:0019228 35 0.019
secretion GO:0046903 307 0.019
myelination GO:0042552 39 0.019
behavior GO:0007610 205 0.019
amide transport GO:0042886 105 0.019
lipid transport GO:0006869 61 0.019
central nervous system development GO:0007417 311 0.019
Mouse
positive regulation of kinase activity GO:0033674 77 0.019
heart morphogenesis GO:0003007 3 0.019
cellular response to lipopolysaccharide GO:0071222 55 0.019
response to carbohydrate GO:0009743 183 0.019
negative regulation of secretion by cell GO:1903531 72 0.019
secretion by cell GO:0032940 248 0.019
myeloid leukocyte activation GO:0002274 36 0.018
glycerolipid metabolic process GO:0046486 67 0.018
odontogenesis GO:0042476 32 0.018
Mouse
regulation of protein modification process GO:0031399 194 0.018
negative regulation of growth GO:0045926 37 0.018
positive regulation of signaling GO:0023056 270 0.018
negative regulation of neurogenesis GO:0050768 78 0.018
neuron apoptotic process GO:0051402 88 0.018
regulation of cellular component size GO:0032535 51 0.018
circulatory system development GO:0072359 134 0.018
Mouse
hepatocyte differentiation GO:0070365 8 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
anatomical structure maturation GO:0071695 2 0.018
positive regulation of leukocyte activation GO:0002696 30 0.018
cell differentiation involved in kidney development GO:0061005 4 0.018
angiogenesis GO:0001525 53 0.018
Mouse
cellular modified amino acid metabolic process GO:0006575 61 0.017
regulation of catalytic activity GO:0050790 304 0.017
Human
negative regulation of neuron differentiation GO:0045665 62 0.017
t cell activation GO:0042110 29 0.017
Mouse
gastrulation GO:0007369 2 0.017
Mouse
transmission of nerve impulse GO:0019226 42 0.017
cellular response to fluid shear stress GO:0071498 4 0.017
mapk cascade GO:0000165 140 0.017
positive regulation of lymphocyte proliferation GO:0050671 20 0.017
membrane organization GO:0061024 94 0.017
epithelial cell proliferation GO:0050673 54 0.017
regulation of fat cell differentiation GO:0045598 3 0.017
regulation of growth GO:0040008 105 0.017
Human
s shaped body morphogenesis GO:0072050 2 0.017
neuron projection guidance GO:0097485 24 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
establishment of tissue polarity GO:0007164 2 0.016
positive regulation of nervous system development GO:0051962 178 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
Human Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.016
Human
antigen receptor mediated signaling pathway GO:0050851 1 0.016
ion homeostasis GO:0050801 212 0.016
regulation of axon extension GO:0030516 24 0.016
response to estradiol GO:0032355 164 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
Human
cellular response to steroid hormone stimulus GO:0071383 93 0.016
Human
ras protein signal transduction GO:0007265 29 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
regulation of lymphocyte activation GO:0051249 34 0.016
kidney development GO:0001822 67 0.016
response to inorganic substance GO:0010035 377 0.016
negative regulation of osteoblast differentiation GO:0045668 2 0.016
molting cycle process GO:0022404 2 0.016
hair follicle development GO:0001942 2 0.016
localization of cell GO:0051674 202 0.016
Human Mouse
camera type eye morphogenesis GO:0048593 2 0.015
limb development GO:0060173 5 0.015
Mouse
amino acid transport GO:0006865 70 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
Human Mouse
organonitrogen compound catabolic process GO:1901565 179 0.015
response to indole 3 methanol GO:0071680 2 0.015
response to axon injury GO:0048678 59 0.015
actin filament based process GO:0030029 86 0.015
intestinal absorption GO:0050892 3 0.015
mitotic spindle organization GO:0007052 2 0.015
carbohydrate metabolic process GO:0005975 130 0.015
salivary gland morphogenesis GO:0007435 1 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
muscle cell proliferation GO:0033002 84 0.015
leukocyte differentiation GO:0002521 30 0.015
Human Mouse
single organism reproductive process GO:0044702 297 0.015
Mouse
response to toxic substance GO:0009636 133 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
Human
epithelial cell differentiation GO:0030855 71 0.015
signal release GO:0023061 145 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
regulation of homeostatic process GO:0032844 101 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
spindle organization GO:0007051 2 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
Human
regulation of cell cell adhesion GO:0022407 14 0.014
Human Mouse
regulation of neuron death GO:1901214 115 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
Human
regulation of vasculature development GO:1901342 44 0.014
metanephric comma shaped body morphogenesis GO:0072278 2 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
cellular response to iron iii ion GO:0071283 3 0.014
leukocyte proliferation GO:0070661 29 0.014
Mouse
positive regulation of response to external stimulus GO:0032103 51 0.014
forebrain development GO:0030900 98 0.014
Mouse
proteolysis GO:0006508 175 0.014
Human
regulation of immunoglobulin production GO:0002637 4 0.013
negative regulation of signaling GO:0023057 157 0.013
Human
cytoskeleton organization GO:0007010 111 0.013
response to hydrogen peroxide GO:0042542 89 0.013
regulation of odontogenesis GO:0042481 4 0.013
diencephalon development GO:0021536 21 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
positive regulation of angiogenesis GO:0045766 28 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
positive regulation of epithelial cell proliferation GO:0050679 32 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
positive regulation of locomotion GO:0040017 102 0.013
Human
glial cell differentiation GO:0010001 65 0.013
Mouse
positive regulation of protein kinase activity GO:0045860 73 0.013
oligodendrocyte differentiation GO:0048709 32 0.013
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.013
regulation of stem cell differentiation GO:2000736 2 0.013
Human
developmental process involved in reproduction GO:0003006 159 0.013
Mouse
regulation of vesicle mediated transport GO:0060627 81 0.013
endochondral bone morphogenesis GO:0060350 7 0.013
somatic stem cell division GO:0048103 2 0.013
Mouse
inflammatory response GO:0006954 150 0.013
protein autophosphorylation GO:0046777 66 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
negative regulation of secretion GO:0051048 82 0.013
appendage development GO:0048736 5 0.013
Mouse
morphogenesis of an epithelium GO:0002009 20 0.012
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
negative regulation of neuron projection development GO:0010977 46 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
wnt signaling pathway GO:0016055 17 0.012
Human Mouse
tissue morphogenesis GO:0048729 22 0.012
Mouse
organophosphate metabolic process GO:0019637 370 0.012
ensheathment of neurons GO:0007272 40 0.012
organelle organization GO:0006996 266 0.012
Human
reactive oxygen species biosynthetic process GO:1903409 8 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
multicellular organism reproduction GO:0032504 233 0.012
growth plate cartilage development GO:0003417 2 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
cellular response to alcohol GO:0097306 87 0.012
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.012
regulation of cellular response to stress GO:0080135 49 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
positive regulation of developmental process GO:0051094 283 0.012
Human
response to monosaccharide GO:0034284 159 0.012
chemical homeostasis GO:0048878 292 0.012
embryonic pattern specification GO:0009880 1 0.012
bone morphogenesis GO:0060349 11 0.012
positive regulation of synaptic plasticity GO:0031915 3 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
cellular response to molecule of bacterial origin GO:0071219 56 0.012
sex differentiation GO:0007548 113 0.012
metanephric s shaped body morphogenesis GO:0072284 2 0.012
positive regulation of defense response GO:0031349 37 0.012
positive regulation of transferase activity GO:0051347 81 0.012
establishment of planar polarity GO:0001736 1 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
positive regulation of molecular function GO:0044093 230 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
Human
positive regulation of phosphate metabolic process GO:0045937 262 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
Human Mouse
cellular homeostasis GO:0019725 252 0.011
blood vessel development GO:0001568 69 0.011
Mouse
phospholipid metabolic process GO:0006644 61 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
response to nutrient GO:0007584 248 0.011
cellular chemical homeostasis GO:0055082 247 0.011
aging GO:0007568 241 0.011
cell cycle checkpoint GO:0000075 2 0.011
biological phase GO:0044848 17 0.011
nucleotide metabolic process GO:0009117 279 0.011
regulation of fc receptor mediated stimulatory signaling pathway GO:0060368 3 0.011
renal system development GO:0072001 67 0.011
mechanoreceptor differentiation GO:0042490 2 0.011
tube formation GO:0035148 3 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
endothelial cell proliferation GO:0001935 20 0.011
intracellular transport GO:0046907 185 0.011
organic anion transport GO:0015711 132 0.011
epithelium development GO:0060429 96 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
transmembrane transport GO:0055085 412 0.011
cytoplasmic transport GO:0016482 115 0.011
cellular response to acid chemical GO:0071229 75 0.011
respiratory system development GO:0060541 45 0.011
Mouse
hematopoietic or lymphoid organ development GO:0048534 36 0.011
Human Mouse
carboxylic acid transport GO:0046942 115 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
positive regulation of cell development GO:0010720 176 0.011
Human
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
comma shaped body morphogenesis GO:0072049 2 0.011
ossification GO:0001503 70 0.011
Human
positive regulation of lymphocyte activation GO:0051251 25 0.011
response to hexose GO:0009746 144 0.011
defense response GO:0006952 194 0.011
reproductive structure development GO:0048608 128 0.011
Mouse
lipid localization GO:0010876 62 0.011
neuron projection extension GO:1990138 26 0.011
negative regulation of cell communication GO:0010648 158 0.011
Human
regulation of mapk cascade GO:0043408 116 0.011
vesicle mediated transport GO:0016192 181 0.011
morphogenesis of a polarized epithelium GO:0001738 1 0.011
response to mechanical stimulus GO:0009612 134 0.010
regulation of homotypic cell cell adhesion GO:0034110 4 0.010
axon guidance GO:0007411 24 0.010
peptide transport GO:0015833 97 0.010
regulation of transferase activity GO:0051338 123 0.010
brain development GO:0007420 247 0.010
Mouse
cellular carbohydrate metabolic process GO:0044262 72 0.010
regulation of tube size GO:0035150 89 0.010
regulation of cellular ketone metabolic process GO:0010565 27 0.010
axon ensheathment GO:0008366 40 0.010
positive regulation of cytokine secretion GO:0050715 9 0.010
regulation of cell cycle g2 m phase transition GO:1902749 4 0.010
specification of organ identity GO:0010092 2 0.010
axis specification GO:0009798 4 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of cell adhesion GO:0030155 52 0.010
Human Mouse
wound healing GO:0042060 122 0.010
positive regulation of cell activation GO:0050867 34 0.010
response to dexamethasone GO:0071548 49 0.010
response to testosterone GO:0033574 55 0.010
generation of precursor metabolites and energy GO:0006091 62 0.010
dna integrity checkpoint GO:0031570 2 0.010

Lef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
connective tissue disease DOID:65 0 0.051
musculoskeletal system disease DOID:17 0 0.051
bone disease DOID:0080001 0 0.051
nervous system disease DOID:863 0 0.026
bone development disease DOID:0080006 0 0.021
sensory system disease DOID:0050155 0 0.021
disease of cellular proliferation DOID:14566 0 0.013
osteochondrodysplasia DOID:2256 0 0.011
organ system cancer DOID:0050686 0 0.010
cancer DOID:162 0 0.010