Rattus norvegicus

382 known processes

Lep

leptin

(Aliases: obese,OB)

Lep biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 130 0.472
head development GO:0060322 247 0.323
anion transport GO:0006820 178 0.318
apoptotic process GO:0006915 381 0.297
cell cell signaling GO:0007267 335 0.283
behavior GO:0007610 205 0.262
carboxylic acid transport GO:0046942 115 0.251
secretion GO:0046903 307 0.240
regulation of nucleic acid templated transcription GO:1903506 380 0.236
response to nutrient levels GO:0031667 370 0.220
transcription from rna polymerase ii promoter GO:0006366 252 0.218
response to peptide hormone GO:0043434 278 0.211
nitrogen compound transport GO:0071705 229 0.210
regulation of rna metabolic process GO:0051252 391 0.210
central nervous system development GO:0007417 311 0.208
rhythmic process GO:0048511 156 0.204
organonitrogen compound biosynthetic process GO:1901566 167 0.204
response to extracellular stimulus GO:0009991 380 0.193
brain development GO:0007420 247 0.190
rna metabolic process GO:0016070 406 0.189
cation transport GO:0006812 382 0.186
oxoacid metabolic process GO:0043436 290 0.179
transcription dna templated GO:0006351 377 0.174
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.171
cellular response to organic cyclic compound GO:0071407 202 0.171
hormone secretion GO:0046879 115 0.167
regulation of synaptic plasticity GO:0048167 70 0.167
synaptic transmission GO:0007268 235 0.163
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.161
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.160
cellular response to nitrogen compound GO:1901699 210 0.153
regulation of secretion GO:0051046 224 0.150
negative regulation of multicellular organismal process GO:0051241 203 0.150
regulation of apoptotic process GO:0042981 335 0.149
positive regulation of cellular biosynthetic process GO:0031328 295 0.146
carbohydrate metabolic process GO:0005975 130 0.144
regulation of peptide transport GO:0090087 87 0.143
regulation of hormone levels GO:0010817 187 0.137
response to corticosteroid GO:0031960 235 0.133
cell type specific apoptotic process GO:0097285 134 0.133
response to estradiol GO:0032355 164 0.131
regulation of blood pressure GO:0008217 83 0.128
cellular divalent inorganic cation homeostasis GO:0072503 162 0.125
response to nicotine GO:0035094 51 0.125
hormone transport GO:0009914 121 0.122
sensory perception GO:0007600 101 0.120
response to toxic substance GO:0009636 133 0.119
response to carbohydrate GO:0009743 183 0.119
signal release GO:0023061 145 0.118
transmembrane transport GO:0055085 412 0.117
learning or memory GO:0007611 90 0.113
single organism biosynthetic process GO:0044711 342 0.109
macromolecular complex assembly GO:0065003 273 0.109
lens development in camera type eye GO:0002088 13 0.107
response to wounding GO:0009611 254 0.104
nucleic acid templated transcription GO:0097659 379 0.104
positive regulation of transcription dna templated GO:0045893 197 0.101
regulation of muscle system process GO:0090257 79 0.100
cytosolic calcium ion homeostasis GO:0051480 140 0.100
macromolecular complex subunit organization GO:0043933 339 0.099
camp metabolic process GO:0046058 63 0.098
response to estrogen GO:0043627 232 0.098
cellular response to hormone stimulus GO:0032870 247 0.097
regulation of hormone secretion GO:0046883 106 0.097
reproductive process GO:0022414 372 0.095
cardiac muscle contraction GO:0060048 27 0.093
regulation of cell proliferation GO:0042127 359 0.093
regeneration GO:0031099 163 0.092
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.091
insulin like growth factor receptor signaling pathway GO:0048009 3 0.090
protein complex assembly GO:0006461 263 0.089
response to cocaine GO:0042220 39 0.089
oxidation reduction process GO:0055114 304 0.088
amide transport GO:0042886 105 0.088
monovalent inorganic cation transport GO:0015672 172 0.087
anatomical structure morphogenesis GO:0009653 298 0.086
secretion by cell GO:0032940 248 0.086
positive regulation of biosynthetic process GO:0009891 319 0.085
fructose 2 6 bisphosphate metabolic process GO:0006003 2 0.085
positive regulation of rna metabolic process GO:0051254 203 0.084
ion transmembrane transport GO:0034220 365 0.083
peptide hormone secretion GO:0030072 84 0.082
response to alkaloid GO:0043279 132 0.082
metal ion transport GO:0030001 289 0.081
gland development GO:0048732 155 0.081
peptide secretion GO:0002790 86 0.081
synaptic transmission glycinergic GO:0060012 2 0.077
negative regulation of hormone secretion GO:0046888 46 0.077
locomotory behavior GO:0007626 15 0.076
cellular response to endogenous stimulus GO:0071495 377 0.075
positive regulation of molecular function GO:0044093 230 0.074
one carbon compound transport GO:0019755 5 0.074
regulation of transcription dna templated GO:0006355 374 0.074
regulation of synaptic transmission GO:0050804 141 0.073
positive regulation of gene expression GO:0010628 244 0.073
response to nutrient GO:0007584 248 0.072
positive regulation of signaling GO:0023056 270 0.072
development of primary female sexual characteristics GO:0046545 56 0.071
regulation of ion transport GO:0043269 245 0.071
negative regulation of signaling GO:0023057 157 0.071
cognition GO:0050890 92 0.071
epithelium development GO:0060429 96 0.071
negative regulation of programmed cell death GO:0043069 183 0.070
organic acid metabolic process GO:0006082 292 0.070
cellular calcium ion homeostasis GO:0006874 160 0.070
protein complex biogenesis GO:0070271 263 0.069
neurological system process GO:0050877 219 0.069
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.069
positive regulation of nucleic acid templated transcription GO:1903508 197 0.068
carboxylic acid metabolic process GO:0019752 289 0.068
response to radiation GO:0009314 137 0.067
regulation of neuron death GO:1901214 115 0.066
neuromuscular process GO:0050905 2 0.065
positive regulation of secretion by cell GO:1903532 128 0.064
regulation of programmed cell death GO:0043067 341 0.064
positive regulation of cellular amine metabolic process GO:0033240 3 0.064
positive regulation of rna biosynthetic process GO:1902680 197 0.063
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.063
response to cytokine GO:0034097 215 0.063
locomotion GO:0040011 237 0.060
positive regulation of cell communication GO:0010647 271 0.059
regulation of defecation GO:2000292 1 0.059
multicellular organism reproduction GO:0032504 233 0.059
cellular metal ion homeostasis GO:0006875 172 0.058
muscle system process GO:0003012 115 0.058
cellular chemical homeostasis GO:0055082 247 0.058
regulation of system process GO:0044057 208 0.057
regulation of rna biosynthetic process GO:2001141 381 0.057
inorganic ion transmembrane transport GO:0098660 229 0.056
response to dexamethasone GO:0071548 49 0.056
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.056
negative regulation of secretion by cell GO:1903531 72 0.056
homeostatic process GO:0042592 331 0.056
positive regulation of peptide hormone secretion GO:0090277 50 0.056
positive regulation of camp metabolic process GO:0030816 31 0.055
response to inorganic substance GO:0010035 377 0.055
long term synaptic potentiation GO:0060291 21 0.055
tissue development GO:0009888 252 0.055
nucleotide metabolic process GO:0009117 279 0.055
hormone mediated signaling pathway GO:0009755 23 0.055
phenol containing compound metabolic process GO:0018958 30 0.054
negative regulation of secretion GO:0051048 82 0.054
response to oxygen levels GO:0070482 265 0.054
vascular process in circulatory system GO:0003018 96 0.053
lymphoid progenitor cell differentiation GO:0002320 2 0.053
sequestering of metal ion GO:0051238 9 0.053
regulation of peptide hormone secretion GO:0090276 80 0.053
rna biosynthetic process GO:0032774 380 0.053
regulation of blood vessel size GO:0050880 89 0.051
lens fiber cell differentiation GO:0070306 3 0.050
single organism carbohydrate metabolic process GO:0044723 118 0.050
potassium ion transport GO:0006813 97 0.050
organic acid transport GO:0015849 116 0.050
regulation of cellular localization GO:0060341 263 0.049
detection of external stimulus GO:0009581 13 0.049
catechol containing compound biosynthetic process GO:0009713 9 0.048
aging GO:0007568 241 0.048
feeding behavior GO:0007631 53 0.048
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.047
positive regulation of phosphate metabolic process GO:0045937 262 0.047
organic anion transport GO:0015711 132 0.047
forebrain development GO:0030900 98 0.047
cell motility GO:0048870 202 0.046
cellular response to steroid hormone stimulus GO:0071383 93 0.046
regulation of secretion by cell GO:1903530 208 0.046
regulation of follicle stimulating hormone secretion GO:0046880 5 0.046
learning GO:0007612 33 0.046
regulation of behavior GO:0050795 61 0.046
response to acid chemical GO:0001101 222 0.045
ovulation cycle process GO:0022602 50 0.045
cyclic nucleotide metabolic process GO:0009187 80 0.045
chemical homeostasis GO:0048878 292 0.045
negative regulation of peptide hormone secretion GO:0090278 30 0.044
response to ethanol GO:0045471 162 0.044
amine metabolic process GO:0009308 38 0.044
response to peptide GO:1901652 292 0.044
purine containing compound metabolic process GO:0072521 253 0.044
programmed cell death GO:0012501 392 0.043
positive regulation of camp biosynthetic process GO:0030819 28 0.043
hepaticobiliary system development GO:0061008 90 0.043
positive regulation of cell proliferation GO:0008284 249 0.043
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.043
response to ketone GO:1901654 182 0.043
regulation of cellular amine metabolic process GO:0033238 8 0.043
regulation of organelle organization GO:0033043 80 0.043
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.042
cellular ion homeostasis GO:0006873 184 0.042
cellular component biogenesis GO:0044085 368 0.042
multi multicellular organism process GO:0044706 138 0.042
calcium ion transport GO:0006816 131 0.042
response to metal ion GO:0010038 253 0.041
heart contraction GO:0060047 57 0.041
regulation of nucleotide biosynthetic process GO:0030808 47 0.041
ion homeostasis GO:0050801 212 0.041
multicellular organismal reproductive process GO:0048609 233 0.040
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.040
positive regulation of multicellular organismal process GO:0051240 387 0.040
steroid metabolic process GO:0008202 73 0.040
synaptic transmission gabaergic GO:0051932 22 0.039
locomotory exploration behavior GO:0035641 1 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.039
catabolic process GO:0009056 351 0.039
cell migration GO:0016477 197 0.038
metal ion homeostasis GO:0055065 186 0.038
regulation of cell differentiation GO:0045595 320 0.038
regulation of body fluid levels GO:0050878 90 0.037
response to hexose GO:0009746 144 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.037
cyclic nucleotide biosynthetic process GO:0009190 63 0.036
peptide transport GO:0015833 97 0.036
negative regulation of gene expression GO:0010629 199 0.036
positive regulation of peptide secretion GO:0002793 52 0.036
response to cesium ion GO:0010164 2 0.036
gonadotropin secretion GO:0032274 8 0.036
regulation of cardiac muscle contraction GO:0055117 17 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.035
response to histamine GO:0034776 3 0.035
negative regulation of cell death GO:0060548 229 0.035
cellular carbohydrate metabolic process GO:0044262 72 0.035
positive regulation of signal transduction GO:0009967 175 0.035
cellular response to organonitrogen compound GO:0071417 197 0.034
calcium ion homeostasis GO:0055074 162 0.034
anion transmembrane transport GO:0098656 77 0.034
single organism intracellular transport GO:1902582 166 0.034
organ regeneration GO:0031100 101 0.033
ovulation cycle GO:0042698 67 0.033
purine ribonucleotide biosynthetic process GO:0009152 81 0.033
organelle organization GO:0006996 266 0.033
amino acid transport GO:0006865 70 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
organophosphate biosynthetic process GO:0090407 143 0.033
heart process GO:0003015 57 0.032
development of primary sexual characteristics GO:0045137 107 0.032
response to monosaccharide GO:0034284 159 0.032
multi organism reproductive process GO:0044703 262 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
maintenance of location GO:0051235 17 0.032
positive regulation of hormone secretion GO:0046887 65 0.032
protein homooligomerization GO:0051260 91 0.032
single organism cellular localization GO:1902580 102 0.032
circadian rhythm GO:0007623 88 0.031
divalent inorganic cation homeostasis GO:0072507 165 0.031
protein complex subunit organization GO:0071822 302 0.031
regulation of metal ion transport GO:0010959 118 0.031
cellular homeostasis GO:0019725 252 0.030
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.030
nucleoside phosphate biosynthetic process GO:1901293 102 0.030
blood circulation GO:0008015 183 0.030
macromolecule localization GO:0033036 252 0.030
proteolysis GO:0006508 175 0.030
negative regulation of response to external stimulus GO:0032102 37 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.030
sequestering of calcium ion GO:0051208 8 0.030
response to growth factor GO:0070848 189 0.030
negative regulation of biosynthetic process GO:0009890 168 0.030
fatty acid metabolic process GO:0006631 99 0.030
acid secretion GO:0046717 48 0.030
circulatory system process GO:0003013 183 0.029
cellular ketone metabolic process GO:0042180 51 0.028
lipid metabolic process GO:0006629 283 0.028
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.028
divalent inorganic cation transport GO:0072511 134 0.028
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.028
negative regulation of apoptotic process GO:0043066 181 0.028
bile acid secretion GO:0032782 5 0.028
cellular cation homeostasis GO:0030003 180 0.028
inorganic cation transmembrane transport GO:0098662 202 0.028
response to glucocorticoid GO:0051384 223 0.028
amine transport GO:0015837 57 0.028
g protein coupled receptor signaling pathway GO:0007186 242 0.028
lipid biosynthetic process GO:0008610 128 0.027
response to reactive oxygen species GO:0000302 120 0.027
negative regulation of transport GO:0051051 136 0.027
positive regulation of leukocyte degranulation GO:0043302 4 0.027
regulation of feeding behavior GO:0060259 14 0.027
sodium ion transport GO:0006814 82 0.027
regulation of transmembrane transport GO:0034762 122 0.026
positive regulation of synaptic transmission GO:0050806 62 0.026
cellular response to cytokine stimulus GO:0071345 127 0.026
defecation GO:0030421 1 0.026
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 2 0.026
insulin secretion GO:0030073 69 0.026
positive regulation of heart contraction GO:0045823 15 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
regulation of membrane potential GO:0042391 110 0.026
camp biosynthetic process GO:0006171 47 0.025
positive regulation of serotonin secretion GO:0014064 1 0.025
cation homeostasis GO:0055080 195 0.025
regulation of tube size GO:0035150 89 0.025
regulation of catalytic activity GO:0050790 304 0.025
response to purine containing compound GO:0014074 126 0.025
regulation of ion homeostasis GO:2000021 63 0.025
cytosolic calcium ion transport GO:0060401 39 0.025
purine nucleotide biosynthetic process GO:0006164 83 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
cellular response to peptide GO:1901653 133 0.025
negative regulation of luteinizing hormone secretion GO:0033685 4 0.025
calcium ion import GO:0070509 22 0.025
cytoskeleton organization GO:0007010 111 0.024
sensory organ development GO:0007423 74 0.024
regulation of adenylate cyclase activity GO:0045761 18 0.024
cellular component movement GO:0006928 248 0.024
response to oxidative stress GO:0006979 186 0.024
regulation of camp biosynthetic process GO:0030817 38 0.024
regulation of cell growth GO:0001558 85 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.024
organic hydroxy compound transport GO:0015850 77 0.024
reproduction GO:0000003 245 0.024
regulation of insulin secretion GO:0050796 65 0.024
regulation of heart rate GO:0002027 16 0.024
negative regulation of cell communication GO:0010648 158 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
organic substance catabolic process GO:1901575 316 0.023
developmental growth GO:0048589 100 0.023
organophosphate metabolic process GO:0019637 370 0.023
organic hydroxy compound metabolic process GO:1901615 115 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
negative regulation of homeostatic process GO:0032845 47 0.023
catecholamine secretion GO:0050432 33 0.023
neuron neuron synaptic transmission GO:0007270 60 0.023
peptidyl amino acid modification GO:0018193 126 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.023
positive regulation of transport GO:0051050 245 0.023
muscle contraction GO:0006936 88 0.023
cellular response to histamine GO:0071420 3 0.022
cellular response to metal ion GO:0071248 55 0.022
divalent metal ion transport GO:0070838 132 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
response to light stimulus GO:0009416 52 0.022
defense response GO:0006952 194 0.022
single organism reproductive process GO:0044702 297 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
cellular response to external stimulus GO:0071496 118 0.022
regulation of molecular function GO:0065009 398 0.022
rhythmic behavior GO:0007622 24 0.022
gastric motility GO:0035482 3 0.022
cellular component morphogenesis GO:0032989 155 0.022
protein oligomerization GO:0051259 191 0.022
calcium ion transport into cytosol GO:0060402 38 0.022
multicellular organismal response to stress GO:0033555 25 0.021
response to testosterone GO:0033574 55 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
limbic system development GO:0021761 38 0.021
gamma aminobutyric acid secretion GO:0014051 6 0.021
regulation of homeostatic process GO:0032844 101 0.021
regulation of protein maturation GO:1903317 50 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
intracellular transport GO:0046907 185 0.021
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.021
carbohydrate derivative biosynthetic process GO:1901137 124 0.021
cellular response to corticosteroid stimulus GO:0071384 69 0.021
cellular macromolecule localization GO:0070727 122 0.021
response to retinoic acid GO:0032526 63 0.021
leukocyte activation involved in immune response GO:0002366 16 0.020
regulation of calcium ion transport GO:0051924 77 0.020
cell projection organization GO:0030030 302 0.020
regulation of wound healing GO:0061041 14 0.020
phospholipase c activating serotonin receptor signaling pathway GO:0007208 2 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
positive regulation of growth GO:0045927 55 0.020
cellular component assembly GO:0022607 360 0.020
phenol containing compound biosynthetic process GO:0046189 9 0.020
catecholamine biosynthetic process GO:0042423 9 0.020
positive regulation of leukocyte activation GO:0002696 30 0.020
cellular amine metabolic process GO:0044106 38 0.020
cellular response to growth factor stimulus GO:0071363 162 0.019
regulation of glucose transport GO:0010827 18 0.019
purine containing compound biosynthetic process GO:0072522 85 0.019
adult locomotory behavior GO:0008344 4 0.019
single organism carbohydrate catabolic process GO:0044724 40 0.019
regulation of developmental growth GO:0048638 45 0.019
monocarboxylic acid transport GO:0015718 52 0.019
regulation of cellular component movement GO:0051270 150 0.019
urinary bladder smooth muscle contraction GO:0014832 4 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
response to calcium ion GO:0051592 59 0.019
response to mineralocorticoid GO:0051385 49 0.019
positive regulation of blood circulation GO:1903524 65 0.019
regulation of cell migration GO:0030334 128 0.019
chemosensory behavior GO:0007635 2 0.018
organic hydroxy compound biosynthetic process GO:1901617 51 0.018
ribonucleotide biosynthetic process GO:0009260 85 0.018
regulation of protein metabolic process GO:0051246 289 0.018
release of sequestered calcium ion into cytosol GO:0051209 25 0.018
regulation of striated muscle contraction GO:0006942 21 0.018
positive regulation of nucleotide metabolic process GO:0045981 91 0.018
negative regulation of signal transduction GO:0009968 83 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
regulation of peptide secretion GO:0002791 82 0.018
positive regulation of cell death GO:0010942 184 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
hematopoietic progenitor cell differentiation GO:0002244 2 0.018
regulation of phosphorylation GO:0042325 248 0.018
negative regulation of amine transport GO:0051953 24 0.018
response to starvation GO:0042594 59 0.018
cellular response to magnesium ion GO:0071286 4 0.018
regulation of response to stress GO:0080134 126 0.018
response to ammonium ion GO:0060359 71 0.018
nucleotide biosynthetic process GO:0009165 98 0.018
adult behavior GO:0030534 16 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
cytoplasmic transport GO:0016482 115 0.017
negative regulation of defecation GO:2000293 1 0.017
positive regulation of ion transport GO:0043270 94 0.017
regulation of cell cycle GO:0051726 73 0.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.017
positive regulation of fat cell differentiation GO:0045600 2 0.017
endocrine hormone secretion GO:0060986 21 0.017
negative regulation of response to wounding GO:1903035 23 0.017
ossification GO:0001503 70 0.017
multicellular organism growth GO:0035264 1 0.017
negative regulation of developmental process GO:0051093 125 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
positive regulation of long term synaptic potentiation GO:1900273 4 0.017
immune system process GO:0002376 204 0.017
response to gonadotropin GO:0034698 34 0.017
positive regulation of insulin secretion GO:0032024 36 0.017
regulation of oxidoreductase activity GO:0051341 11 0.017
male sex differentiation GO:0046661 64 0.017
cellular protein localization GO:0034613 122 0.016
reactive oxygen species metabolic process GO:0072593 37 0.016
peptidyl tyrosine modification GO:0018212 72 0.016
positive regulation of heart rate GO:0010460 9 0.016
protein localization GO:0008104 191 0.016
positive regulation of cell motility GO:2000147 97 0.016
regulation of systemic arterial blood pressure GO:0003073 30 0.016
regulation of ion transmembrane transport GO:0034765 121 0.016
synapse organization GO:0050808 46 0.016
memory GO:0007613 54 0.016
cation transmembrane transport GO:0098655 263 0.016
cerebellar granule cell precursor proliferation GO:0021930 1 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
cellular response to lipid GO:0071396 201 0.016
membrane depolarization GO:0051899 32 0.016
response to organophosphorus GO:0046683 102 0.016
regulation of carbohydrate metabolic process GO:0006109 41 0.016
involuntary skeletal muscle contraction GO:0003011 2 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.016
lymphocyte migration GO:0072676 3 0.016
cellular response to nutrient levels GO:0031669 60 0.016
muscle structure development GO:0061061 87 0.016
purine containing compound catabolic process GO:0072523 138 0.016
regulation of camp metabolic process GO:0030814 43 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
regulation of cell activation GO:0050865 50 0.015
regulation of catecholamine secretion GO:0050433 32 0.015
negative regulation of neuron death GO:1901215 69 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
membrane organization GO:0061024 94 0.015
canalicular bile acid transport GO:0015722 5 0.015
protein localization to membrane GO:0072657 36 0.015
serotonin secretion GO:0001820 6 0.015
negative regulation of calcium ion import GO:0090281 2 0.015
regulation of cytoskeleton organization GO:0051493 49 0.015
regulation of signal transduction GO:0009966 318 0.015
fear response GO:0042596 9 0.015
positive regulation of adenylate cyclase activity GO:0045762 12 0.015
fat cell proliferation GO:0070341 2 0.015
cellular response to glucocorticoid stimulus GO:0071385 68 0.014
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
thyroid gland development GO:0030878 1 0.014
protein heterooligomerization GO:0051291 89 0.014
cell fate commitment involved in pattern specification GO:0060581 2 0.014
response to glucose GO:0009749 136 0.014
sexual reproduction GO:0019953 148 0.014
endocrine process GO:0050886 32 0.014
muscle cell proliferation GO:0033002 84 0.014
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.014
startle response GO:0001964 2 0.014
olfactory behavior GO:0042048 2 0.014
renal system process GO:0003014 40 0.014
positive regulation of cardiac muscle contraction GO:0060452 4 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
vasoconstriction GO:0042310 54 0.014
positive regulation of developmental process GO:0051094 283 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.013
regulation of the force of heart contraction by chemical signal GO:0003057 2 0.013
regulation of neural precursor cell proliferation GO:2000177 16 0.013
triglyceride homeostasis GO:0070328 2 0.013
establishment of protein localization GO:0045184 141 0.013
cellular response to gonadotropin stimulus GO:0071371 17 0.013
response to transition metal nanoparticle GO:1990267 122 0.013

Lep disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
obesity DOID:9970 0 0.107
nutrition disease DOID:374 0 0.107
overnutrition DOID:654 0 0.107
disease of metabolism DOID:0014667 0 0.107
acquired metabolic disease DOID:0060158 0 0.107
nervous system disease DOID:863 0 0.036
disease of anatomical entity DOID:7 0 0.036
endocrine system disease DOID:28 0 0.020
central nervous system disease DOID:331 0 0.016