Rattus norvegicus

0 known processes

Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

(Aliases: Gpr48)

Lgr4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.437
Mouse
organic acid metabolic process GO:0006082 292 0.426
cellular response to peptide hormone stimulus GO:0071375 120 0.419
transcription dna templated GO:0006351 377 0.414
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.325
cellular response to organonitrogen compound GO:0071417 197 0.310
response to tumor necrosis factor GO:0034612 56 0.300
regulation of nucleic acid templated transcription GO:1903506 380 0.295
Mouse
monocarboxylic acid metabolic process GO:0032787 152 0.289
carboxylic acid metabolic process GO:0019752 289 0.284
negative regulation of cellular metabolic process GO:0031324 281 0.278
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.276
Rat
response to extracellular stimulus GO:0009991 380 0.268
response to cytokine GO:0034097 215 0.259
cellular response to peptide GO:1901653 133 0.255
cellular response to stress GO:0033554 269 0.254
regulation of rna biosynthetic process GO:2001141 381 0.232
Mouse
protein phosphorylation GO:0006468 345 0.221
cellular lipid metabolic process GO:0044255 208 0.219
regulation of multicellular organismal development GO:2000026 376 0.215
Mouse
negative regulation of metabolic process GO:0009892 331 0.212
Mouse
rna biosynthetic process GO:0032774 380 0.206
Mouse
oxoacid metabolic process GO:0043436 290 0.206
positive regulation of nervous system development GO:0051962 178 0.176
carbohydrate metabolic process GO:0005975 130 0.175
nucleic acid templated transcription GO:0097659 379 0.174
Mouse
cellular response to lipid GO:0071396 201 0.173
homeostatic process GO:0042592 331 0.173
Rat
negative regulation of signaling GO:0023057 157 0.173
Mouse
cellular response to nitrogen compound GO:1901699 210 0.170
regulation of signal transduction GO:0009966 318 0.166
Human Mouse Rat
carboxylic acid biosynthetic process GO:0046394 83 0.166
regulation of protein metabolic process GO:0051246 289 0.165
cellular response to insulin stimulus GO:0032869 81 0.160
macromolecular complex subunit organization GO:0043933 339 0.159
single organism biosynthetic process GO:0044711 342 0.156
Rat
positive regulation of cell development GO:0010720 176 0.155
positive regulation of protein metabolic process GO:0051247 178 0.155
negative regulation of macromolecule metabolic process GO:0010605 260 0.153
Mouse
negative regulation of response to stimulus GO:0048585 155 0.149
Mouse
positive regulation of transport GO:0051050 245 0.146
Rat
response to peptide hormone GO:0043434 278 0.144
cellular component assembly GO:0022607 360 0.140
chemical homeostasis GO:0048878 292 0.134
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.131
Mouse Rat
cellular response to hormone stimulus GO:0032870 247 0.130
Rat
protein complex subunit organization GO:0071822 302 0.129
regulation of hormone levels GO:0010817 187 0.127
Rat
cation transport GO:0006812 382 0.126
Rat
response to inorganic substance GO:0010035 377 0.125
negative regulation of protein metabolic process GO:0051248 114 0.123
behavior GO:0007610 205 0.122
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.122
Mouse
negative regulation of rna biosynthetic process GO:1902679 118 0.121
Mouse
cellular component biogenesis GO:0044085 368 0.120
regulation of cellular component biogenesis GO:0044087 86 0.119
growth GO:0040007 165 0.119
positive regulation of signaling GO:0023056 270 0.119
Human Mouse Rat
reproductive process GO:0022414 372 0.117
Mouse Rat
positive regulation of cellular component organization GO:0051130 200 0.116
regulation of cellular component organization GO:0051128 368 0.115
cation homeostasis GO:0055080 195 0.112
Rat
cellular ion homeostasis GO:0006873 184 0.112
Rat
regulation of secretion GO:0051046 224 0.112
Mouse
negative regulation of developmental process GO:0051093 125 0.111
transcription from rna polymerase ii promoter GO:0006366 252 0.110
aging GO:0007568 241 0.110
macromolecular complex assembly GO:0065003 273 0.110
cellular ketone metabolic process GO:0042180 51 0.108
tissue development GO:0009888 252 0.106
Mouse
positive regulation of cell differentiation GO:0045597 217 0.105
positive regulation of response to stimulus GO:0048584 285 0.101
Human Mouse Rat
positive regulation of developmental process GO:0051094 283 0.100
Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.097
central nervous system development GO:0007417 311 0.097
Rat
cellular chemical homeostasis GO:0055082 247 0.095
Rat
neurological system process GO:0050877 219 0.095
response to ethanol GO:0045471 162 0.095
protein modification by small protein conjugation GO:0032446 31 0.095
response to nutrient levels GO:0031667 370 0.094
negative regulation of gene expression GO:0010629 199 0.094
Mouse
protein maturation GO:0051604 68 0.094
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.093
response to decreased oxygen levels GO:0036293 237 0.093
small molecule biosynthetic process GO:0044283 124 0.093
multi organism reproductive process GO:0044703 262 0.093
Mouse
cell adhesion GO:0007155 110 0.093
single organism carbohydrate metabolic process GO:0044723 118 0.093
metal ion homeostasis GO:0055065 186 0.092
Rat
cognition GO:0050890 92 0.091
multicellular organismal reproductive process GO:0048609 233 0.091
Mouse Rat
fatty acid metabolic process GO:0006631 99 0.089
intracellular protein transport GO:0006886 79 0.089
Rat
positive regulation of molecular function GO:0044093 230 0.089
Rat
regulation of cell differentiation GO:0045595 320 0.088
synaptic growth at neuromuscular junction GO:0051124 1 0.088
positive regulation of gene expression GO:0010628 244 0.088
Mouse
proteolysis GO:0006508 175 0.087
positive regulation of locomotion GO:0040017 102 0.087
cellular response to tumor necrosis factor GO:0071356 46 0.087
response to toxic substance GO:0009636 133 0.087
immune system process GO:0002376 204 0.085
Mouse
multi multicellular organism process GO:0044706 138 0.084
regulation of rna metabolic process GO:0051252 391 0.084
Mouse
cellular catabolic process GO:0044248 295 0.083
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.083
regulation of cellular localization GO:0060341 263 0.082
Mouse Rat
reproduction GO:0000003 245 0.082
Mouse Rat
regulation of protein phosphorylation GO:0001932 183 0.082
negative regulation of cellular biosynthetic process GO:0031327 161 0.081
Mouse
regulation of transcription dna templated GO:0006355 374 0.081
Mouse
transmembrane transport GO:0055085 412 0.081
regulation of cell development GO:0060284 263 0.079
response to oxidative stress GO:0006979 186 0.079
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.078
response to monosaccharide GO:0034284 159 0.076
regulation of nervous system development GO:0051960 264 0.075
divalent metal ion transport GO:0070838 132 0.075
Rat
multicellular organism reproduction GO:0032504 233 0.074
Mouse Rat
regulation of molecular function GO:0065009 398 0.073
Rat
cellular amino acid metabolic process GO:0006520 107 0.073
negative regulation of cellular protein metabolic process GO:0032269 106 0.072
single organism cellular localization GO:1902580 102 0.072
Rat
response to molecule of bacterial origin GO:0002237 194 0.072
response to hexose GO:0009746 144 0.071
programmed cell death GO:0012501 392 0.071
negative regulation of signal transduction GO:0009968 83 0.071
Mouse
locomotion GO:0040011 237 0.070
negative regulation of cell death GO:0060548 229 0.070
lipid metabolic process GO:0006629 283 0.070
Rat
actin filament based process GO:0030029 86 0.069
regulation of intracellular signal transduction GO:1902531 218 0.068
Rat
response to insulin GO:0032868 133 0.068
positive regulation of biosynthetic process GO:0009891 319 0.067
Mouse Rat
negative regulation of biosynthetic process GO:0009890 168 0.067
Mouse
response to corticosteroid GO:0031960 235 0.067
protein complex assembly GO:0006461 263 0.067
divalent inorganic cation homeostasis GO:0072507 165 0.066
Rat
catabolic process GO:0009056 351 0.066
response to external biotic stimulus GO:0043207 221 0.065
nucleobase containing small molecule metabolic process GO:0055086 316 0.064
Rat
response to peptide GO:1901652 292 0.063
regulation of cell proliferation GO:0042127 359 0.063
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.062
Mouse
cellular protein localization GO:0034613 122 0.062
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.061
Rat
response to purine containing compound GO:0014074 126 0.061
renal system development GO:0072001 67 0.061
Mouse
heart morphogenesis GO:0003007 3 0.061
positive regulation of cell communication GO:0010647 271 0.061
Human Mouse Rat
dna metabolic process GO:0006259 96 0.061
cellular response to molecule of bacterial origin GO:0071219 56 0.060
positive regulation of cell motility GO:2000147 97 0.059
response to nutrient GO:0007584 248 0.059
response to oxygen levels GO:0070482 265 0.058
response to metal ion GO:0010038 253 0.058
apoptotic process GO:0006915 381 0.058
positive regulation of catalytic activity GO:0043085 184 0.058
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.057
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.056
secretion GO:0046903 307 0.055
Mouse Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.055
Mouse
response to organophosphorus GO:0046683 102 0.055
negative regulation of multicellular organismal process GO:0051241 203 0.055
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.054
Rat
anion transport GO:0006820 178 0.054
Rat
cellular component morphogenesis GO:0032989 155 0.054
positive regulation of cellular component movement GO:0051272 102 0.054
regulation of ion transport GO:0043269 245 0.054
Rat
negative regulation of cell communication GO:0010648 158 0.054
Mouse
negative regulation of transcription dna templated GO:0045892 116 0.054
Mouse
positive regulation of neurogenesis GO:0050769 165 0.054
reproductive structure development GO:0048608 128 0.054
Mouse Rat
developmental process involved in reproduction GO:0003006 159 0.054
Mouse Rat
positive regulation of cell migration GO:0030335 96 0.053
endocytosis GO:0006897 84 0.053
single organism reproductive process GO:0044702 297 0.053
Mouse Rat
cell type specific apoptotic process GO:0097285 134 0.052
positive regulation of cell proliferation GO:0008284 249 0.052
Rat
intracellular signal transduction GO:0035556 314 0.052
Rat
kidney development GO:0001822 67 0.052
Mouse
regulation of programmed cell death GO:0043067 341 0.052
regulation of neuron death GO:1901214 115 0.051
positive regulation of rna biosynthetic process GO:1902680 197 0.051
Mouse
positive regulation of cellular biosynthetic process GO:0031328 295 0.051
Mouse Rat
amine metabolic process GO:0009308 38 0.051
positive regulation of cellular protein metabolic process GO:0032270 167 0.051
positive regulation of phosphate metabolic process GO:0045937 262 0.051
Rat
cellular calcium ion homeostasis GO:0006874 160 0.051
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.051
Rat
response to other organism GO:0051707 220 0.051
single organism organelle organization GO:1902589 180 0.050
small gtpase mediated signal transduction GO:0007264 36 0.050
protein processing GO:0016485 68 0.049
response to mechanical stimulus GO:0009612 134 0.049
regulation of phosphorylation GO:0042325 248 0.049
negative regulation of transport GO:0051051 136 0.049
Mouse
cell motility GO:0048870 202 0.048
anterior posterior pattern specification GO:0009952 1 0.048
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.048
positive regulation of multicellular organismal process GO:0051240 387 0.048
Mouse
response to biotic stimulus GO:0009607 226 0.047
protein complex biogenesis GO:0070271 263 0.047
response to glucocorticoid GO:0051384 223 0.047
neuron differentiation GO:0030182 368 0.047
cell cell signaling GO:0007267 335 0.046
Mouse
regulation of protein modification process GO:0031399 194 0.046
defense response GO:0006952 194 0.046
cellular response to cytokine stimulus GO:0071345 127 0.046
signal transduction by phosphorylation GO:0023014 144 0.046
response to carbohydrate GO:0009743 183 0.046
positive regulation of phosphorylation GO:0042327 177 0.046
protein oligomerization GO:0051259 191 0.045
cellular response to growth factor stimulus GO:0071363 162 0.045
positive regulation of protein phosphorylation GO:0001934 135 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.045
Mouse Rat
response to temperature stimulus GO:0009266 94 0.045
cellular divalent inorganic cation homeostasis GO:0072503 162 0.045
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.044
divalent inorganic cation transport GO:0072511 134 0.044
Rat
response to bacterium GO:0009617 200 0.044
positive regulation of programmed cell death GO:0043068 157 0.044
reactive oxygen species metabolic process GO:0072593 37 0.044
alpha amino acid metabolic process GO:1901605 71 0.044
cell projection organization GO:0030030 302 0.044
regulation of catalytic activity GO:0050790 304 0.044
Rat
response to camp GO:0051591 91 0.044
neuron death GO:0070997 127 0.043
embryo development GO:0009790 49 0.043
cellular response to organic cyclic compound GO:0071407 202 0.043
cell morphogenesis GO:0000902 142 0.043
response to acid chemical GO:0001101 222 0.043
single organism behavior GO:0044708 130 0.043
positive regulation of transcription dna templated GO:0045893 197 0.043
Mouse
positive regulation of signal transduction GO:0009967 175 0.043
Human Mouse Rat
negative regulation of protein phosphorylation GO:0001933 44 0.043
response to amino acid GO:0043200 75 0.043
cellular amine metabolic process GO:0044106 38 0.042
regulation of t cell chemotaxis GO:0010819 1 0.042
jak stat cascade GO:0007259 26 0.042
positive regulation of apoptotic process GO:0043065 154 0.041
positive regulation of ion transport GO:0043270 94 0.041
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.041
male mating behavior GO:0060179 3 0.040
response to growth factor GO:0070848 189 0.040
regulation of synaptic transmission GO:0050804 141 0.040
taxis GO:0042330 67 0.040
positive regulation of neuron differentiation GO:0045666 126 0.040
negative regulation of phosphorus metabolic process GO:0010563 80 0.040
organic acid biosynthetic process GO:0016053 83 0.040
response to radiation GO:0009314 137 0.039
establishment of protein localization to organelle GO:0072594 44 0.039
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.039
Mouse
regulation of membrane potential GO:0042391 110 0.038
cellular homeostasis GO:0019725 252 0.038
Rat
synapse organization GO:0050808 46 0.038
organophosphate biosynthetic process GO:0090407 143 0.038
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.038
macromolecule localization GO:0033036 252 0.038
Mouse Rat
cytoplasmic transport GO:0016482 115 0.038
Rat
immune response GO:0006955 104 0.038
cellular response to biotic stimulus GO:0071216 59 0.037
response to glucose GO:0009749 136 0.037
protein homooligomerization GO:0051260 91 0.036
regulation of protein localization GO:0032880 81 0.036
Mouse
unsaturated fatty acid metabolic process GO:0033559 39 0.036
protein transport GO:0015031 132 0.036
Mouse Rat
ion homeostasis GO:0050801 212 0.036
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.035
positive regulation of cell death GO:0010942 184 0.035
carbohydrate derivative biosynthetic process GO:1901137 124 0.035
Rat
peptidyl serine phosphorylation GO:0018105 33 0.035
cytoskeleton organization GO:0007010 111 0.035
response to reactive oxygen species GO:0000302 120 0.035
organic substance catabolic process GO:1901575 316 0.035
gastrulation GO:0007369 2 0.035
response to transition metal nanoparticle GO:1990267 122 0.035
pyrimidine nucleobase metabolic process GO:0006206 8 0.034
cell activation GO:0001775 97 0.034
single organism catabolic process GO:0044712 283 0.034
regulation of response to external stimulus GO:0032101 106 0.034
reactive oxygen species biosynthetic process GO:1903409 8 0.034
cellular macromolecule localization GO:0070727 122 0.033
Rat
tube development GO:0035295 89 0.033
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.033
Rat
cellular carbohydrate metabolic process GO:0044262 72 0.033
gamete generation GO:0007276 124 0.033
Mouse
positive regulation of rna metabolic process GO:0051254 203 0.033
Mouse
cellular cation homeostasis GO:0030003 180 0.033
Rat
enzyme linked receptor protein signaling pathway GO:0007167 116 0.032
ion transmembrane transport GO:0034220 365 0.032
organelle organization GO:0006996 266 0.032
head development GO:0060322 247 0.032
development of primary sexual characteristics GO:0045137 107 0.032
Rat
regulation of lipid metabolic process GO:0019216 68 0.032
Rat
brain development GO:0007420 247 0.031
localization of cell GO:0051674 202 0.031
regulation of neuron differentiation GO:0045664 208 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.031
Mouse
cellular response to acid chemical GO:0071229 75 0.031
purine nucleoside triphosphate metabolic process GO:0009144 141 0.031
cellular response to reactive oxygen species GO:0034614 55 0.031
response to hypoxia GO:0001666 231 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.031
Mouse
cellular amide metabolic process GO:0043603 44 0.030
regulation of fatty acid metabolic process GO:0019217 18 0.030
regulation of metal ion transport GO:0010959 118 0.030
Rat
lipid biosynthetic process GO:0008610 128 0.030
Rat
sexual reproduction GO:0019953 148 0.030
Mouse
cellular component movement GO:0006928 248 0.030
vesicle mediated transport GO:0016192 181 0.030
Rat
regulation of immune system process GO:0002682 123 0.030
Mouse
non canonical wnt signaling pathway GO:0035567 3 0.029
embryonic pattern specification GO:0009880 1 0.029
calcium ion homeostasis GO:0055074 162 0.029
Rat
regulation of lipid biosynthetic process GO:0046890 38 0.029
Rat
response to lipopolysaccharide GO:0032496 191 0.029
negative regulation of molecular function GO:0044092 133 0.029
regulation of protein kinase activity GO:0045859 105 0.028
response to starvation GO:0042594 59 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.028
Mouse
regulation of canonical wnt signaling pathway GO:0060828 4 0.028
Human Mouse
synaptic transmission GO:0007268 235 0.028
response to cadmium ion GO:0046686 35 0.028
regulation of cell motility GO:2000145 131 0.027
reproductive system development GO:0061458 128 0.027
Mouse Rat
regulation of neurogenesis GO:0050767 247 0.027
epithelium development GO:0060429 96 0.027
Mouse
intracellular transport GO:0046907 185 0.027
Rat
monosaccharide metabolic process GO:0005996 61 0.027
insulin receptor signaling pathway GO:0008286 24 0.026
rhythmic process GO:0048511 156 0.026
Rat
release of cytochrome c from mitochondria GO:0001836 8 0.026
regulation of kinase activity GO:0043549 117 0.026
protein tetramerization GO:0051262 38 0.026
regulation of proteolysis GO:0030162 66 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.026
regulation of homeostatic process GO:0032844 101 0.026
Rat
negative regulation of cell proliferation GO:0008285 119 0.025
neuron apoptotic process GO:0051402 88 0.025
negative regulation of cell differentiation GO:0045596 99 0.025
positive regulation of immune system process GO:0002684 90 0.025
Mouse
cellular response to lipopolysaccharide GO:0071222 55 0.025
metal ion transport GO:0030001 289 0.024
Rat
peptidyl amino acid modification GO:0018193 126 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
neuron development GO:0048666 286 0.024
calcium ion transport GO:0006816 131 0.024
Rat
long chain fatty acid metabolic process GO:0001676 32 0.024
hormone metabolic process GO:0042445 69 0.024
Rat
multicellular organism growth GO:0035264 1 0.024
sex differentiation GO:0007548 113 0.023
Mouse Rat
regulation of transferase activity GO:0051338 123 0.023
energy derivation by oxidation of organic compounds GO:0015980 46 0.023
post embryonic development GO:0009791 6 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.023
cytosolic calcium ion homeostasis GO:0051480 140 0.023
Rat
response to ketone GO:1901654 182 0.023
activation of cysteine type endopeptidase activity GO:0097202 4 0.023
neurotransmitter gated ion channel clustering GO:0072578 3 0.023
cellular amino acid catabolic process GO:0009063 21 0.023
alpha amino acid catabolic process GO:1901606 20 0.023
g protein coupled receptor signaling pathway GO:0007186 242 0.023
Rat
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.023
generation of precursor metabolites and energy GO:0006091 62 0.022
b cell differentiation GO:0030183 2 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
regulation of organelle organization GO:0033043 80 0.022
cell cycle GO:0007049 101 0.022
protein targeting to nucleus GO:0044744 35 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.022
mapk cascade GO:0000165 140 0.022
oxidation reduction process GO:0055114 304 0.022
transmission of nerve impulse GO:0019226 42 0.022
establishment of planar polarity GO:0001736 1 0.022
negative regulation of phosphate metabolic process GO:0045936 80 0.022
response to wounding GO:0009611 254 0.022
lipid localization GO:0010876 62 0.022
Rat
carboxylic acid transport GO:0046942 115 0.022
Rat
activation of protein kinase activity GO:0032147 47 0.022
glucose metabolic process GO:0006006 52 0.021
cell junction assembly GO:0034329 18 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
Rat
cellular response to oxidative stress GO:0034599 76 0.021
morphogenesis of an epithelium GO:0002009 20 0.021
Mouse
macroautophagy GO:0016236 4 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
Rat
organic acid catabolic process GO:0016054 49 0.021
prostaglandin transport GO:0015732 8 0.021
axon guidance GO:0007411 24 0.021
hexose metabolic process GO:0019318 58 0.021
response to hydrogen peroxide GO:0042542 89 0.021
monocarboxylic acid biosynthetic process GO:0072330 48 0.021
digestive system development GO:0055123 41 0.021
protein localization to organelle GO:0033365 57 0.021
Rat
gonad development GO:0008406 104 0.021
Rat
biological adhesion GO:0022610 110 0.021
behavioral response to ethanol GO:0048149 1 0.021
regulation of calcium ion transport GO:0051924 77 0.021
Rat
apoptotic signaling pathway GO:0097190 27 0.021
regulation of cell migration GO:0030334 128 0.020
protein heterooligomerization GO:0051291 89 0.020
regulation of cellular catabolic process GO:0031329 101 0.020
regulation of cell adhesion GO:0030155 52 0.020
endocardial cushion development GO:0003197 1 0.020
regulation of growth GO:0040008 105 0.020
response to amine GO:0014075 46 0.020
protein autophosphorylation GO:0046777 66 0.020
regulation of response to stress GO:0080134 126 0.020
Mouse
regulation of neuron apoptotic process GO:0043523 83 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
Rat
glycosyl compound metabolic process GO:1901657 182 0.020
wnt signaling pathway GO:0016055 17 0.020
Human Mouse
protein localization GO:0008104 191 0.020
Mouse Rat
embryonic morphogenesis GO:0048598 14 0.020
purine ribonucleoside catabolic process GO:0046130 124 0.020
secretion by cell GO:0032940 248 0.020
Mouse
organonitrogen compound catabolic process GO:1901565 179 0.020
regulation of defense response GO:0031347 68 0.020
Mouse
negative regulation of rna metabolic process GO:0051253 123 0.020
Mouse
response to vitamin GO:0033273 131 0.020
lipid transport GO:0006869 61 0.019
Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
Mouse
axonogenesis GO:0007409 71 0.019
male sex differentiation GO:0046661 64 0.019
Mouse
regulation of neuron projection development GO:0010975 161 0.019
regulation of jak stat cascade GO:0046425 21 0.019
cell migration GO:0016477 197 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
Rat
reactive nitrogen species metabolic process GO:2001057 1 0.019
regulation of smoothened signaling pathway GO:0008589 2 0.019
cellular response to alcohol GO:0097306 87 0.019
cytokine production GO:0001816 61 0.019
Mouse
axon ensheathment GO:0008366 40 0.019
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
hormone secretion GO:0046879 115 0.019
regulation of circadian sleep wake cycle GO:0042749 18 0.019
negative regulation of mapk cascade GO:0043409 20 0.019
cell junction organization GO:0034330 21 0.019
regulation of cell projection organization GO:0031344 175 0.019
regulation of apoptotic process GO:0042981 335 0.019
regulation of locomotion GO:0040012 148 0.019
regulation of behavior GO:0050795 61 0.019
establishment of protein localization GO:0045184 141 0.018
Mouse Rat
regulation of catabolic process GO:0009894 113 0.018
response to fatty acid GO:0070542 65 0.018
positive regulation of icosanoid secretion GO:0032305 7 0.018
regulation of dna metabolic process GO:0051052 60 0.018
female pregnancy GO:0007565 122 0.018
activation of mapkkk activity GO:0000185 1 0.018
single organism intracellular transport GO:1902582 166 0.018
Rat
regulation of establishment of protein localization GO:0070201 69 0.018
Mouse
cell substrate adhesion GO:0031589 29 0.018
response to estrogen GO:0043627 232 0.018
negative regulation of intracellular signal transduction GO:1902532 38 0.018
circadian rhythm GO:0007623 88 0.018
neuronal action potential GO:0019228 35 0.018
regulation of establishment of planar polarity GO:0090175 2 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
Mouse
organ morphogenesis GO:0009887 75 0.018
Mouse
cellular response to abiotic stimulus GO:0071214 85 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
Rat
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.017
fatty acid transport GO:0015908 25 0.017
Rat
regeneration GO:0031099 163 0.017
cellular response to steroid hormone stimulus GO:0071383 93 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.017
nitrogen compound transport GO:0071705 229 0.017
positive regulation of protein modification process GO:0031401 142 0.017
response to alkaloid GO:0043279 132 0.017
monocarboxylic acid transport GO:0015718 52 0.017
Rat
cardiovascular system development GO:0072358 134 0.017
gland development GO:0048732 155 0.017
insulin secretion GO:0030073 69 0.017
negative regulation of neuron death GO:1901215 69 0.017
learning or memory GO:0007611 90 0.017
glial cell differentiation GO:0010001 65 0.016
regulation of protein serine threonine kinase activity GO:0071900 64 0.016
regulation of peptidase activity GO:0052547 55 0.016
collateral sprouting GO:0048668 2 0.016
neural crest cell development GO:0014032 2 0.016
positive regulation of growth GO:0045927 55 0.016
negative regulation of phosphorylation GO:0042326 57 0.016
negative regulation of protein modification process GO:0031400 52 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
cellular response to metal ion GO:0071248 55 0.016
digestive tract development GO:0048565 39 0.016
protein ubiquitination GO:0016567 28 0.016

Lgr4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.020
disease of anatomical entity DOID:7 0 0.020
eye and adnexa disease DOID:1492 0 0.020
nervous system disease DOID:863 0 0.020
eye disease DOID:5614 0 0.020