Rattus norvegicus

258 known processes

Lhcgr

luteinizing hormone/choriogonadotropin receptor

(Aliases: LSH-R,LSHR,Lhr,LH/CG-R)

Lhcgr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.490
androgen biosynthetic process GO:0006702 10 0.447
carboxylic acid biosynthetic process GO:0046394 83 0.430
progesterone biosynthetic process GO:0006701 3 0.424
small molecule biosynthetic process GO:0044283 124 0.232
Mouse
oxoacid metabolic process GO:0043436 290 0.224
female pregnancy GO:0007565 122 0.175
reproductive structure development GO:0048608 128 0.174
Mouse Rat
carboxylic acid metabolic process GO:0019752 289 0.151
macromolecular complex subunit organization GO:0043933 339 0.150
testosterone biosynthetic process GO:0061370 5 0.127
organic acid biosynthetic process GO:0016053 83 0.123
developmental process involved in reproduction GO:0003006 159 0.115
Mouse Rat
rhythmic process GO:0048511 156 0.114
Mouse Rat
androgen metabolic process GO:0008209 14 0.113
multi organism reproductive process GO:0044703 262 0.112
Mouse
cellular response to organic cyclic compound GO:0071407 202 0.109
reproductive process GO:0022414 372 0.096
Mouse Rat
response to estradiol GO:0032355 164 0.091
steroid biosynthetic process GO:0006694 48 0.090
c21 steroid hormone biosynthetic process GO:0006700 10 0.090
multi multicellular organism process GO:0044706 138 0.089
progesterone metabolic process GO:0042448 8 0.085
reproduction GO:0000003 245 0.080
Mouse Rat
organic hydroxy compound metabolic process GO:1901615 115 0.078
Mouse
estrogen biosynthetic process GO:0006703 6 0.076
response to growth factor GO:0070848 189 0.075
cellular amino acid metabolic process GO:0006520 107 0.073
response to corticosteroid GO:0031960 235 0.071
regulation of secretion by cell GO:1903530 208 0.071
multicellular organismal reproductive process GO:0048609 233 0.068
Mouse Rat
multicellular organism reproduction GO:0032504 233 0.068
Mouse Rat
response to inorganic substance GO:0010035 377 0.066
cellular response to endogenous stimulus GO:0071495 377 0.066
leydig cell differentiation GO:0033327 8 0.064
single organism reproductive process GO:0044702 297 0.063
Mouse Rat
regulation of cellular localization GO:0060341 263 0.062
cellular response to peptide GO:1901653 133 0.061
amine metabolic process GO:0009308 38 0.059
epithelium development GO:0060429 96 0.059
gonad development GO:0008406 104 0.059
Mouse Rat
positive regulation of secretion GO:0051047 140 0.057
regulation of system process GO:0044057 208 0.057
c21 steroid hormone metabolic process GO:0008207 14 0.057
cellular amine metabolic process GO:0044106 38 0.054
monocarboxylic acid metabolic process GO:0032787 152 0.050
regulation of secretion GO:0051046 224 0.050
fatty acid metabolic process GO:0006631 99 0.048
gland development GO:0048732 155 0.048
regulation of molecular function GO:0065009 398 0.046
cellular ketone metabolic process GO:0042180 51 0.046
unsaturated fatty acid metabolic process GO:0033559 39 0.045
protein complex subunit organization GO:0071822 302 0.043
response to glucocorticoid GO:0051384 223 0.043
regulation of body fluid levels GO:0050878 90 0.042
cellular response to luteinizing hormone stimulus GO:0071373 5 0.041
cellular response to peptide hormone stimulus GO:0071375 120 0.040
grooming behavior GO:0007625 4 0.039
macromolecular complex assembly GO:0065003 273 0.039
single organism biosynthetic process GO:0044711 342 0.038
immune response GO:0006955 104 0.038
cellular component biogenesis GO:0044085 368 0.038
negative regulation of molecular function GO:0044092 133 0.037
cellular metal ion homeostasis GO:0006875 172 0.036
innate immune response GO:0045087 35 0.036
intracellular transport GO:0046907 185 0.036
development of primary sexual characteristics GO:0045137 107 0.035
Mouse Rat
cation transport GO:0006812 382 0.035
head development GO:0060322 247 0.034
cellular response to glucocorticoid stimulus GO:0071385 68 0.034
circulatory system development GO:0072359 134 0.034
response to vitamin GO:0033273 131 0.034
response to metal ion GO:0010038 253 0.033
behavioral response to ethanol GO:0048149 1 0.033
cellular lipid metabolic process GO:0044255 208 0.033
lipid biosynthetic process GO:0008610 128 0.032
single organism intracellular transport GO:1902582 166 0.032
lipid metabolic process GO:0006629 283 0.031
prepulse inhibition GO:0060134 1 0.031
response to acid chemical GO:0001101 222 0.031
secondary alcohol metabolic process GO:1902652 2 0.031
sexual reproduction GO:0019953 148 0.030
Mouse
cellular response to organonitrogen compound GO:0071417 197 0.030
cellular response to hormone stimulus GO:0032870 247 0.029
chemokine metabolic process GO:0050755 3 0.028
response to nutrient levels GO:0031667 370 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
response to alkaloid GO:0043279 132 0.028
regulation of amino acid transport GO:0051955 25 0.028
renal system process GO:0003014 40 0.028
regulation of rna metabolic process GO:0051252 391 0.028
cellular modified amino acid biosynthetic process GO:0042398 18 0.027
response to fungicide GO:0060992 20 0.027
positive regulation of transport GO:0051050 245 0.027
behavior GO:0007610 205 0.026
regulation of anatomical structure morphogenesis GO:0022603 141 0.026
response to cadmium ion GO:0046686 35 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
reproductive system development GO:0061458 128 0.025
Mouse Rat
regulation of hormone levels GO:0010817 187 0.025
icosanoid metabolic process GO:0006690 38 0.025
regulation of phosphorylation GO:0042325 248 0.025
regulation of blood pressure GO:0008217 83 0.025
mapk cascade GO:0000165 140 0.024
positive regulation of norepinephrine secretion GO:0010701 4 0.024
secretion by cell GO:0032940 248 0.024
carbohydrate metabolic process GO:0005975 130 0.024
Mouse
cellular response to lipid GO:0071396 201 0.024
phenol containing compound metabolic process GO:0018958 30 0.024
ovulation cycle GO:0042698 67 0.024
Mouse Rat
monovalent inorganic cation transport GO:0015672 172 0.024
endocrine system development GO:0035270 30 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
protein complex assembly GO:0006461 263 0.023
maternal behavior GO:0042711 5 0.023
muscle cell differentiation GO:0042692 52 0.023
response to peptide GO:1901652 292 0.023
cellular response to steroid hormone stimulus GO:0071383 93 0.023
cellular response to interleukin 1 GO:0071347 37 0.022
liver development GO:0001889 90 0.022
circulatory system process GO:0003013 183 0.022
brain development GO:0007420 247 0.022
response to peptide hormone GO:0043434 278 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.021
negative regulation of innate immune response GO:0045824 4 0.021
apoptotic process GO:0006915 381 0.021
cellular component assembly GO:0022607 360 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
response to ketone GO:1901654 182 0.020
cardiovascular system development GO:0072358 134 0.020
regulation of renal sodium excretion GO:0035813 20 0.020
transmembrane transport GO:0055085 412 0.020
response to luteinizing hormone GO:0034699 5 0.020
heart process GO:0003015 57 0.020
cellular ion homeostasis GO:0006873 184 0.020
positive regulation of secretion by cell GO:1903532 128 0.020
aldosterone secretion GO:0035932 3 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
negative regulation of signal transduction GO:0009968 83 0.019
fatty acid derivative metabolic process GO:1901568 38 0.019
developmental growth GO:0048589 100 0.019
renal filtration GO:0097205 10 0.019
response to insulin GO:0032868 133 0.019
response to transforming growth factor beta GO:0071559 46 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
response to toxic substance GO:0009636 133 0.018
eating behavior GO:0042755 21 0.018
growth GO:0040007 165 0.018
sex differentiation GO:0007548 113 0.018
Mouse Rat
regulation of apoptotic process GO:0042981 335 0.018
response to xenobiotic stimulus GO:0009410 23 0.018
nitrogen compound transport GO:0071705 229 0.017
cell cell signaling GO:0007267 335 0.017
negative regulation of metabolic process GO:0009892 331 0.017
salivary gland development GO:0007431 3 0.017
response to corticosterone GO:0051412 40 0.016
steroid metabolic process GO:0008202 73 0.016
epiboly GO:0090504 2 0.016
maternal aggressive behavior GO:0002125 3 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
cellular response to tumor necrosis factor GO:0071356 46 0.016
response to herbicide GO:0009635 16 0.016
protein complex biogenesis GO:0070271 263 0.016
cellular macromolecular complex assembly GO:0034622 58 0.016
muscle structure development GO:0061061 87 0.016
renal sodium excretion GO:0035812 20 0.015
cardiac chamber development GO:0003205 1 0.015
multicellular organismal water homeostasis GO:0050891 4 0.015
linoleic acid metabolic process GO:0043651 4 0.015
cellular response to insulin stimulus GO:0032869 81 0.015
cellular response to camp GO:0071320 26 0.015
trichloroethylene metabolic process GO:0018979 1 0.015
regulation of systemic arterial blood pressure GO:0003073 30 0.015
protein phosphorylation GO:0006468 345 0.015
response to purine containing compound GO:0014074 126 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
regulation of anion transport GO:0044070 43 0.015
protein heterooligomerization GO:0051291 89 0.015
positive regulation of leukocyte degranulation GO:0043302 4 0.015
embryo development GO:0009790 49 0.015
regulation of anatomical structure size GO:0090066 135 0.015
axis specification GO:0009798 4 0.015
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
programmed cell death GO:0012501 392 0.014
cell projection morphogenesis GO:0048858 123 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
sulfur compound metabolic process GO:0006790 70 0.014
purine containing compound metabolic process GO:0072521 253 0.014
hormone metabolic process GO:0042445 69 0.014
response to reactive oxygen species GO:0000302 120 0.014
cellular response to gonadotropin stimulus GO:0071371 17 0.014
Mouse
regulation of excretion GO:0044062 21 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
insulin like growth factor receptor signaling pathway GO:0048009 3 0.014
response to ethanol GO:0045471 162 0.014
hormone secretion GO:0046879 115 0.014
cellular modified amino acid metabolic process GO:0006575 61 0.013
catechol containing compound biosynthetic process GO:0009713 9 0.013
vitamin biosynthetic process GO:0009110 3 0.013
cellular response to alcohol GO:0097306 87 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
cytoplasmic transport GO:0016482 115 0.013
regulation of blood circulation GO:1903522 110 0.013
cell growth GO:0016049 104 0.013
cellular response to lipopolysaccharide GO:0071222 55 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
response to temperature stimulus GO:0009266 94 0.013
dicarboxylic acid metabolic process GO:0043648 42 0.013
regulation of transferase activity GO:0051338 123 0.013
response to other organism GO:0051707 220 0.013
circadian rhythm GO:0007623 88 0.013
single organism cellular localization GO:1902580 102 0.013
response to nutrient GO:0007584 248 0.013
negative regulation of organic acid transport GO:0032891 14 0.012
multi organism behavior GO:0051705 24 0.012
rna biosynthetic process GO:0032774 380 0.012
secretion GO:0046903 307 0.012
protein homotrimerization GO:0070207 15 0.012
response to follicle stimulating hormone GO:0032354 18 0.012
cation transmembrane transport GO:0098655 263 0.012
response to organophosphorus GO:0046683 102 0.012
response to camp GO:0051591 91 0.012
regulation of mapk cascade GO:0043408 116 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
negative regulation of cell death GO:0060548 229 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
protein polymerization GO:0051258 22 0.012
negative regulation of circadian sleep wake cycle non rem sleep GO:0042323 2 0.012
single organism catabolic process GO:0044712 283 0.012
action potential GO:0001508 54 0.012
cellular response to stress GO:0033554 269 0.012
response to extracellular stimulus GO:0009991 380 0.012
alpha amino acid catabolic process GO:1901606 20 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
hormone biosynthetic process GO:0042446 25 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
sleep GO:0030431 30 0.011
hepaticobiliary system development GO:0061008 90 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
neurological system process GO:0050877 219 0.011
Human
regulation of signal transduction GO:0009966 318 0.011
negative regulation of cell communication GO:0010648 158 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
hormone transport GO:0009914 121 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
signal release GO:0023061 145 0.011
positive regulation of signal transduction GO:0009967 175 0.011
positive regulation of catecholamine secretion GO:0033605 13 0.011
cell cycle GO:0007049 101 0.011
halogenated hydrocarbon metabolic process GO:0042197 4 0.011
positive regulation of peptide hormone secretion GO:0090277 50 0.011
macromolecule localization GO:0033036 252 0.011
ion homeostasis GO:0050801 212 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.011
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.011
cation homeostasis GO:0055080 195 0.011
catecholamine biosynthetic process GO:0042423 9 0.011
cellular hormone metabolic process GO:0034754 49 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
cytokine secretion GO:0050663 15 0.010
regulation of protein metabolic process GO:0051246 289 0.010
sodium ion homeostasis GO:0055078 23 0.010
regulation of organic acid transport GO:0032890 35 0.010
one carbon compound transport GO:0019755 5 0.010
cardiac conduction GO:0061337 2 0.010
negative regulation of transport GO:0051051 136 0.010
amine transport GO:0015837 57 0.010
calcitriol biosynthetic process from calciol GO:0036378 2 0.010
blood circulation GO:0008015 183 0.010
regulation of kinase activity GO:0043549 117 0.010
anterior posterior pattern specification GO:0009952 1 0.010
vitamin d biosynthetic process GO:0042368 2 0.010
response to oxidative stress GO:0006979 186 0.010
renin angiotensin regulation of aldosterone production GO:0002018 3 0.010
intracellular signal transduction GO:0035556 314 0.010

Lhcgr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.086
disease of anatomical entity DOID:7 0 0.072
kidney disease DOID:557 0 0.072
urinary system disease DOID:18 0 0.072
steroid inherited metabolic disorder DOID:1701 0 0.018
lipid metabolism disorder DOID:3146 0 0.018
congenital adrenal hyperplasia DOID:0050811 0 0.018
inherited metabolic disorder DOID:655 0 0.018
connective tissue disease DOID:65 0 0.017
musculoskeletal system disease DOID:17 0 0.017
congenital hypothyroidism DOID:0050328 0 0.013
hypothyroidism DOID:1459 0 0.013
endocrine system disease DOID:28 0 0.013
thyroid gland disease DOID:50 0 0.013
nervous system disease DOID:863 0 0.011
respiratory system disease DOID:1579 0 0.011
lower respiratory tract disease DOID:0050161 0 0.011