Rattus norvegicus

0 known processes

Lmod2

leiomodin 2 (cardiac)

Lmod2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
striated muscle contraction GO:0006941 44 0.153
cardiac muscle contraction GO:0060048 27 0.095
response to oxygen levels GO:0070482 265 0.080
muscle system process GO:0003012 115 0.077
oxidation reduction process GO:0055114 304 0.061
blood circulation GO:0008015 183 0.059
cellular component biogenesis GO:0044085 368 0.048
macromolecular complex subunit organization GO:0043933 339 0.044
response to nutrient levels GO:0031667 370 0.044
regulation of molecular function GO:0065009 398 0.043
heart contraction GO:0060047 57 0.042
anatomical structure morphogenesis GO:0009653 298 0.041
nucleotide metabolic process GO:0009117 279 0.040
response to hypoxia GO:0001666 231 0.039
regulation of catalytic activity GO:0050790 304 0.038
cellular component assembly GO:0022607 360 0.038
cytoskeleton organization GO:0007010 111 0.036
regulation of transcription dna templated GO:0006355 374 0.036
response to peptide hormone GO:0043434 278 0.036
response to decreased oxygen levels GO:0036293 237 0.036
neuron differentiation GO:0030182 368 0.035
protein complex biogenesis GO:0070271 263 0.035
regulation of cell proliferation GO:0042127 359 0.035
organic substance catabolic process GO:1901575 316 0.035
circulatory system process GO:0003013 183 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.034
negative regulation of cell death GO:0060548 229 0.034
response to peptide GO:1901652 292 0.033
single organism catabolic process GO:0044712 283 0.033
cellular catabolic process GO:0044248 295 0.033
response to extracellular stimulus GO:0009991 380 0.033
macromolecular complex assembly GO:0065003 273 0.033
regulation of multicellular organismal development GO:2000026 376 0.032
nucleic acid templated transcription GO:0097659 379 0.031
protein complex assembly GO:0006461 263 0.031
positive regulation of developmental process GO:0051094 283 0.031
regulation of rna metabolic process GO:0051252 391 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
regulation of muscle contraction GO:0006937 53 0.029
actin filament based movement GO:0030048 16 0.029
protein oligomerization GO:0051259 191 0.029
muscle contraction GO:0006936 88 0.029
cellular homeostasis GO:0019725 252 0.029
organelle organization GO:0006996 266 0.028
response to oxidative stress GO:0006979 186 0.028
transmembrane transport GO:0055085 412 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
response to mechanical stimulus GO:0009612 134 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.026
ion homeostasis GO:0050801 212 0.026
regulation of programmed cell death GO:0043067 341 0.026
protein complex subunit organization GO:0071822 302 0.025
regulation of system process GO:0044057 208 0.025
potassium ion transmembrane transport GO:0071805 71 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
positive regulation of cell differentiation GO:0045597 217 0.024
proteolysis GO:0006508 175 0.024
defense response GO:0006952 194 0.024
regulation of cellular component organization GO:0051128 368 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.023
cation homeostasis GO:0055080 195 0.023
metal ion transport GO:0030001 289 0.023
homeostatic process GO:0042592 331 0.023
catabolic process GO:0009056 351 0.023
regulation of membrane potential GO:0042391 110 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
regulation of catabolic process GO:0009894 113 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
negative regulation of metabolic process GO:0009892 331 0.022
apoptotic process GO:0006915 381 0.021
heart process GO:0003015 57 0.021
actin mediated cell contraction GO:0070252 12 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
cellular ion homeostasis GO:0006873 184 0.020
regulation of hydrolase activity GO:0051336 143 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
response to inorganic substance GO:0010035 377 0.020
rna metabolic process GO:0016070 406 0.020
neuron projection development GO:0031175 273 0.020
cellular response to external stimulus GO:0071496 118 0.020
regulation of blood circulation GO:1903522 110 0.020
intracellular transport GO:0046907 185 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
cellular cation homeostasis GO:0030003 180 0.019
negative regulation of molecular function GO:0044092 133 0.019
circulatory system development GO:0072359 134 0.019
regulation of cell differentiation GO:0045595 320 0.019
rna biosynthetic process GO:0032774 380 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
regulation of muscle system process GO:0090257 79 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
cell projection organization GO:0030030 302 0.019
single organism biosynthetic process GO:0044711 342 0.019
response to toxic substance GO:0009636 133 0.019
cellular amine metabolic process GO:0044106 38 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
heart morphogenesis GO:0003007 3 0.019
single organism organelle organization GO:1902589 180 0.019
response to other organism GO:0051707 220 0.018
oxoacid metabolic process GO:0043436 290 0.018
regulation of striated muscle contraction GO:0006942 21 0.018
monovalent inorganic cation transport GO:0015672 172 0.018
organic acid metabolic process GO:0006082 292 0.018
cardiac muscle cell contraction GO:0086003 10 0.018
cardiac ventricle development GO:0003231 1 0.018
transcription dna templated GO:0006351 377 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
programmed cell death GO:0012501 392 0.018
response to purine containing compound GO:0014074 126 0.018
ras protein signal transduction GO:0007265 29 0.018
ventricular cardiac muscle cell action potential GO:0086005 2 0.018
maintenance of location GO:0051235 17 0.018
cardiac chamber development GO:0003205 1 0.017
purine containing compound metabolic process GO:0072521 253 0.017
cardiovascular system development GO:0072358 134 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
carbohydrate metabolic process GO:0005975 130 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
amine metabolic process GO:0009308 38 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
heterocycle catabolic process GO:0046700 167 0.017
response to external biotic stimulus GO:0043207 221 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
regulation of cardiac muscle contraction GO:0055117 17 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
establishment of protein localization GO:0045184 141 0.016
response to reactive oxygen species GO:0000302 120 0.016
organophosphate metabolic process GO:0019637 370 0.016
regulation of actin filament based movement GO:1903115 12 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
spindle organization GO:0007051 2 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
aromatic compound catabolic process GO:0019439 168 0.016
response to insulin GO:0032868 133 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
sequestering of metal ion GO:0051238 9 0.015
multi organism reproductive process GO:0044703 262 0.015
response to nutrient GO:0007584 248 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
cation transmembrane transport GO:0098655 263 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
intracellular signal transduction GO:0035556 314 0.015
potassium ion transport GO:0006813 97 0.015
macromolecule localization GO:0033036 252 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
nucleotide catabolic process GO:0009166 139 0.014
metal ion homeostasis GO:0055065 186 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
cation transport GO:0006812 382 0.014
cellular response to insulin stimulus GO:0032869 81 0.014
protein homooligomerization GO:0051260 91 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
chemical homeostasis GO:0048878 292 0.014
muscle tissue development GO:0060537 58 0.014
cardiac muscle tissue morphogenesis GO:0055008 1 0.014
single organism reproductive process GO:0044702 297 0.014
cell growth GO:0016049 104 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
actin filament based process GO:0030029 86 0.014
positive regulation of gene expression GO:0010628 244 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
regulation of cellular component movement GO:0051270 150 0.014
inorganic ion transmembrane transport GO:0098660 229 0.013
regulation of growth GO:0040008 105 0.013
alpha amino acid metabolic process GO:1901605 71 0.013
sequestering of calcium ion GO:0051208 8 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
positive regulation of cell development GO:0010720 176 0.013
response to alkaloid GO:0043279 132 0.013
cofactor metabolic process GO:0051186 95 0.013
cell type specific apoptotic process GO:0097285 134 0.013
regulation of cell development GO:0060284 263 0.013
negative regulation of signaling GO:0023057 157 0.013
positive regulation of molecular function GO:0044093 230 0.013
organophosphate catabolic process GO:0046434 148 0.013
calcium ion homeostasis GO:0055074 162 0.012
striated muscle cell development GO:0055002 26 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
regulation of cell growth GO:0001558 85 0.012
cellular response to peptide GO:1901653 133 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
cellular chemical homeostasis GO:0055082 247 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
cellular component movement GO:0006928 248 0.012
rho protein signal transduction GO:0007266 11 0.012
glycogen biosynthetic process GO:0005978 15 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
response to bacterium GO:0009617 200 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
muscle cell differentiation GO:0042692 52 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
single organism intracellular transport GO:1902582 166 0.012
regulation of homeostatic process GO:0032844 101 0.012
regulation of actin filament based process GO:0032970 42 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
response to growth factor GO:0070848 189 0.012
regulation of apoptotic process GO:0042981 335 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
regulation of anatomical structure size GO:0090066 135 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
response to corticosteroid GO:0031960 235 0.011
cellular potassium ion transport GO:0071804 72 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
response to vitamin GO:0033273 131 0.011
positive regulation of cell death GO:0010942 184 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
negative regulation of gene expression GO:0010629 199 0.011
gamete generation GO:0007276 124 0.011
nucleoside catabolic process GO:0009164 126 0.011
response to heat GO:0009408 60 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
immunoglobulin mediated immune response GO:0016064 4 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
negative regulation of cell communication GO:0010648 158 0.011
multicellular organismal movement GO:0050879 17 0.010
skeletal muscle tissue development GO:0007519 31 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
axis specification GO:0009798 4 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
regulation of heart contraction GO:0008016 48 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
cell cell signaling GO:0007267 335 0.010

Lmod2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 0 0.108
disease of anatomical entity DOID:7 0 0.108
musculoskeletal system disease DOID:17 0 0.060
muscular disease DOID:0080000 0 0.053
muscle tissue disease DOID:66 0 0.053
myopathy DOID:423 0 0.050
cardiomyopathy DOID:0050700 0 0.037
heart disease DOID:114 0 0.037
intrinsic cardiomyopathy DOID:0060036 0 0.025
muscular dystrophy DOID:9884 0 0.022
dilated cardiomyopathy DOID:12930 0 0.021
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.011