Rattus norvegicus

0 known processes

Lpar2

lysophosphatidic acid receptor 2

(Aliases: Edg4,RGD1561336,Pbx4)

Lpar2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to nutrient levels GO:0031667 370 0.197
Rat
organic acid metabolic process GO:0006082 292 0.172
Rat
reproductive process GO:0022414 372 0.170
Rat
cellular lipid metabolic process GO:0044255 208 0.162
Rat
response to acid chemical GO:0001101 222 0.155
cellular response to hormone stimulus GO:0032870 247 0.147
inorganic cation transmembrane transport GO:0098662 202 0.139
positive regulation of gene expression GO:0010628 244 0.125
Rat
epithelial cell differentiation GO:0030855 71 0.121
Rat
cation transmembrane transport GO:0098655 263 0.120
cellular response to oxygen containing compound GO:1901701 386 0.111
aging GO:0007568 241 0.110
Rat
lipid metabolic process GO:0006629 283 0.105
Rat
cation transport GO:0006812 382 0.090
Rat
cellular response to stress GO:0033554 269 0.087
cellular response to corticosteroid stimulus GO:0071384 69 0.087
cellular ketone metabolic process GO:0042180 51 0.087
Rat
cell cell signaling GO:0007267 335 0.086
Rat
regulation of neurogenesis GO:0050767 247 0.084
Rat
carboxylic acid metabolic process GO:0019752 289 0.083
Rat
tissue development GO:0009888 252 0.082
Rat
homeostatic process GO:0042592 331 0.082
Rat
regulation of neuron differentiation GO:0045664 208 0.082
Rat
cellular chemical homeostasis GO:0055082 247 0.081
Rat
choline transport GO:0015871 4 0.081
brain development GO:0007420 247 0.080
central nervous system development GO:0007417 311 0.079
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.077
Rat
ion transmembrane transport GO:0034220 365 0.077
response to carbohydrate GO:0009743 183 0.077
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.076
Rat
regulation of programmed cell death GO:0043067 341 0.076
Rat
catecholamine transport GO:0051937 37 0.072
Rat
sulfur compound transport GO:0072348 8 0.072
behavior GO:0007610 205 0.072
Rat
transcription dna templated GO:0006351 377 0.072
Rat
response to inorganic substance GO:0010035 377 0.068
oxoacid metabolic process GO:0043436 290 0.067
Rat
reproduction GO:0000003 245 0.066
Rat
response to nutrient GO:0007584 248 0.065
Rat
response to decreased oxygen levels GO:0036293 237 0.065
cellular response to glucocorticoid stimulus GO:0071385 68 0.065
response to external biotic stimulus GO:0043207 221 0.062
Rat
multicellular organismal reproductive process GO:0048609 233 0.061
Rat
response to hypoxia GO:0001666 231 0.059
response to oxygen levels GO:0070482 265 0.058
Rat
multi multicellular organism process GO:0044706 138 0.057
Rat
secretion GO:0046903 307 0.057
Rat
rhythmic process GO:0048511 156 0.056
regulation of cellular ketone metabolic process GO:0010565 27 0.055
Rat
response to estradiol GO:0032355 164 0.054
amine metabolic process GO:0009308 38 0.053
response to estrogen GO:0043627 232 0.052
regulation of cellular amine metabolic process GO:0033238 8 0.049
positive regulation of transcription dna templated GO:0045893 197 0.049
Rat
single organism reproductive process GO:0044702 297 0.048
Rat
catabolic process GO:0009056 351 0.047
Rat
gland development GO:0048732 155 0.047
negative regulation of multicellular organismal process GO:0051241 203 0.047
Rat
regulation of transcription dna templated GO:0006355 374 0.047
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.047
Rat
cellular response to endogenous stimulus GO:0071495 377 0.046
head development GO:0060322 247 0.046
metal ion homeostasis GO:0055065 186 0.045
Rat
negative regulation of metabolic process GO:0009892 331 0.045
Rat
response to corticosteroid GO:0031960 235 0.044
chemical homeostasis GO:0048878 292 0.044
Rat
transmembrane transport GO:0055085 412 0.043
multi organism reproductive process GO:0044703 262 0.043
Rat
negative regulation of nervous system development GO:0051961 79 0.043
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.043
negative regulation of cell proliferation GO:0008285 119 0.042
bmp signaling pathway GO:0030509 4 0.042
glutathione transport GO:0034635 2 0.042
regulation of protein metabolic process GO:0051246 289 0.041
multicellular organism growth GO:0035264 1 0.041
antibiotic transport GO:0042891 2 0.040
positive regulation of nervous system development GO:0051962 178 0.040
Rat
regulation of molecular function GO:0065009 398 0.040
Rat
regulation of cell development GO:0060284 263 0.039
Rat
cellular metal ion homeostasis GO:0006875 172 0.038
Rat
regulation of hormone levels GO:0010817 187 0.038
Rat
neuron differentiation GO:0030182 368 0.038
Rat
mesoderm development GO:0007498 2 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.037
Rat
regulation of rna metabolic process GO:0051252 391 0.037
Rat
rna biosynthetic process GO:0032774 380 0.037
Rat
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.036
macromolecular complex subunit organization GO:0043933 339 0.036
Rat
cell morphogenesis GO:0000902 142 0.035
multicellular organism reproduction GO:0032504 233 0.035
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.034
response to other organism GO:0051707 220 0.034
Rat
cellular amine metabolic process GO:0044106 38 0.034
response to monosaccharide GO:0034284 159 0.034
developmental process involved in reproduction GO:0003006 159 0.034
ion homeostasis GO:0050801 212 0.034
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
Rat
response to metal ion GO:0010038 253 0.032
response to growth factor GO:0070848 189 0.032
response to ethanol GO:0045471 162 0.031
Rat
response to extracellular stimulus GO:0009991 380 0.031
Rat
metal ion transport GO:0030001 289 0.031
Rat
rna metabolic process GO:0016070 406 0.031
Rat
response to cocaine GO:0042220 39 0.031
Rat
dendrite morphogenesis GO:0048813 43 0.031
inorganic ion transmembrane transport GO:0098660 229 0.031
divalent metal ion transport GO:0070838 132 0.031
Rat
programmed cell death GO:0012501 392 0.031
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
Rat
sexual reproduction GO:0019953 148 0.030
Rat
regulation of locomotion GO:0040012 148 0.030
Rat
female pregnancy GO:0007565 122 0.030
Rat
cell part morphogenesis GO:0032990 123 0.030
regulation of response to stress GO:0080134 126 0.029
Rat
anion transmembrane transport GO:0098656 77 0.029
negative regulation of cellular metabolic process GO:0031324 281 0.029
Rat
protein complex assembly GO:0006461 263 0.029
positive regulation of neurogenesis GO:0050769 165 0.029
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
Rat
regulation of transferase activity GO:0051338 123 0.028
organ regeneration GO:0031100 101 0.028
cellular response to growth factor stimulus GO:0071363 162 0.028
tube development GO:0035295 89 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
cell projection organization GO:0030030 302 0.027
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.027
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.027
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.027
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.027
regulation of cell projection organization GO:0031344 175 0.027
Rat
positive regulation of molecular function GO:0044093 230 0.027
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.027
organelle organization GO:0006996 266 0.027
Rat
positive regulation of developmental process GO:0051094 283 0.027
Rat
regulation of protein modification process GO:0031399 194 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
regulation of secretion GO:0051046 224 0.026
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
small molecule biosynthetic process GO:0044283 124 0.026
epithelium development GO:0060429 96 0.026
Rat
immune system process GO:0002376 204 0.026
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.025
neuron projection development GO:0031175 273 0.025
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.025
Rat
regulation of apoptotic process GO:0042981 335 0.025
Rat
cellular cation homeostasis GO:0030003 180 0.025
Rat
calcium ion homeostasis GO:0055074 162 0.024
Rat
norepinephrine transport GO:0015874 18 0.024
alcohol metabolic process GO:0006066 77 0.024
purine containing compound metabolic process GO:0072521 253 0.024
Rat
protein phosphorylation GO:0006468 345 0.024
regulation of cell motility GO:2000145 131 0.023
Rat
regulation of phosphate metabolic process GO:0019220 349 0.023
Rat
cellular ion homeostasis GO:0006873 184 0.023
Rat
response to cytokine GO:0034097 215 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
Rat
hormone secretion GO:0046879 115 0.023
Rat
positive regulation of rna metabolic process GO:0051254 203 0.023
Rat
sex differentiation GO:0007548 113 0.023
carbohydrate metabolic process GO:0005975 130 0.023
response to osmotic stress GO:0006970 42 0.023
response to glucose GO:0009749 136 0.023
positive regulation of transport GO:0051050 245 0.022
Rat
cellular component assembly GO:0022607 360 0.022
Rat
cellular component morphogenesis GO:0032989 155 0.022
response to peptide hormone GO:0043434 278 0.022
neuron development GO:0048666 286 0.022
Rat
response to vitamin GO:0033273 131 0.022
apoptotic process GO:0006915 381 0.022
Rat
inflammatory response GO:0006954 150 0.022
Rat
regulation of cell differentiation GO:0045595 320 0.021
Rat
positive regulation of cellular component organization GO:0051130 200 0.021
Rat
embryonic pattern specification GO:0009880 1 0.021
positive regulation of cellular biosynthetic process GO:0031328 295 0.021
Rat
regulation of system process GO:0044057 208 0.021
response to peptide GO:1901652 292 0.021
reproductive system development GO:0061458 128 0.021
carboxylic acid catabolic process GO:0046395 49 0.021
Rat
c21 steroid hormone biosynthetic process GO:0006700 10 0.021
dendrite development GO:0016358 72 0.020
Rat
chromosome segregation GO:0007059 2 0.020
regulation of cell proliferation GO:0042127 359 0.020
Rat
cardiovascular system development GO:0072358 134 0.020
regulation of synaptic transmission GO:0050804 141 0.020
Rat
response to oxidative stress GO:0006979 186 0.020
tissue regeneration GO:0042246 36 0.020
cellular calcium ion homeostasis GO:0006874 160 0.019
Rat
endocrine system development GO:0035270 30 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
Rat
response to ammonium ion GO:0060359 71 0.019
Rat
positive regulation of secretion GO:0051047 140 0.019
nitrogen compound transport GO:0071705 229 0.018
Rat
cellular catabolic process GO:0044248 295 0.018
Rat
response to transition metal nanoparticle GO:1990267 122 0.018
regeneration GO:0031099 163 0.018
monocarboxylic acid transport GO:0015718 52 0.018
developmental growth GO:0048589 100 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
lipid localization GO:0010876 62 0.018
protein complex subunit organization GO:0071822 302 0.018
Rat
thyroid gland development GO:0030878 1 0.018
response to molecule of fungal origin GO:0002238 3 0.018
calcium ion transport GO:0006816 131 0.018
Rat
cellular response to lipid GO:0071396 201 0.018
response to hexose GO:0009746 144 0.017
nucleic acid templated transcription GO:0097659 379 0.017
Rat
negative regulation of protein metabolic process GO:0051248 114 0.017
response to toxic substance GO:0009636 133 0.017
positive regulation of signaling GO:0023056 270 0.017
neuron projection morphogenesis GO:0048812 122 0.016
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.016
establishment of tissue polarity GO:0007164 2 0.016
regulation of neuron death GO:1901214 115 0.016
hepaticobiliary system development GO:0061008 90 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
Rat
single organism biosynthetic process GO:0044711 342 0.016
regulation of neuron projection development GO:0010975 161 0.016
Rat
negative regulation of apoptotic process GO:0043066 181 0.016
organic acid transport GO:0015849 116 0.016
sulfur compound metabolic process GO:0006790 70 0.016
single organism intracellular transport GO:1902582 166 0.015
proteolysis GO:0006508 175 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
Rat
oligopeptide transport GO:0006857 4 0.015
muscle system process GO:0003012 115 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
modified amino acid transport GO:0072337 12 0.015
circadian rhythm GO:0007623 88 0.015
tripeptide transport GO:0042939 2 0.015
response to ketone GO:1901654 182 0.015
response to organophosphorus GO:0046683 102 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
regulation of cellular response to stress GO:0080135 49 0.015
toxin transport GO:1901998 3 0.015
positive regulation of hormone secretion GO:0046887 65 0.014
gamete generation GO:0007276 124 0.014
Rat
organic acid biosynthetic process GO:0016053 83 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
Rat
cellular homeostasis GO:0019725 252 0.014
Rat
telencephalon development GO:0021537 62 0.014
adult locomotory behavior GO:0008344 4 0.014
negative regulation of cell development GO:0010721 82 0.014
Rat
actin filament based process GO:0030029 86 0.014
Rat
regulation of phosphorylation GO:0042325 248 0.014
cell projection morphogenesis GO:0048858 123 0.014
regulation of ion transport GO:0043269 245 0.014
Rat
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
Rat
monovalent inorganic cation transport GO:0015672 172 0.014
positive regulation of calcium ion transport GO:0051928 36 0.014
Rat
organic hydroxy compound transport GO:0015850 77 0.014
Rat
gonad development GO:0008406 104 0.014
cytoplasmic transport GO:0016482 115 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
Rat
mesoderm morphogenesis GO:0048332 1 0.014
hormone mediated signaling pathway GO:0009755 23 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
Rat
regulation of nervous system development GO:0051960 264 0.014
Rat
response to alkaloid GO:0043279 132 0.013
Rat
heart morphogenesis GO:0003007 3 0.013
secretion by cell GO:0032940 248 0.013
Rat
macromolecular complex assembly GO:0065003 273 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
Rat
cellular response to follicle stimulating hormone stimulus GO:0071372 13 0.013
lipid storage GO:0019915 1 0.013
tube formation GO:0035148 3 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
Rat
anion transport GO:0006820 178 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
Rat
positive regulation of neuron projection development GO:0010976 99 0.013
Rat
growth GO:0040007 165 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
Rat
leukocyte activation GO:0045321 76 0.013
Rat
cell cycle checkpoint GO:0000075 2 0.013
monoamine transport GO:0015844 43 0.013
Rat
reproductive structure development GO:0048608 128 0.013
cellular response to oxidative stress GO:0034599 76 0.012
regulation of secretion by cell GO:1903530 208 0.012
Rat
positive regulation of cell development GO:0010720 176 0.012
Rat
peptidyl serine phosphorylation GO:0018105 33 0.012
regulation of protein kinase activity GO:0045859 105 0.012
peptidyl amino acid modification GO:0018193 126 0.012
gastrulation GO:0007369 2 0.012
digestive system development GO:0055123 41 0.012
intracellular transport GO:0046907 185 0.012
divalent inorganic cation transport GO:0072511 134 0.012
Rat
macromolecule localization GO:0033036 252 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
neurotransmitter uptake GO:0001504 3 0.012
cell cycle GO:0007049 101 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
Rat
cell type specific apoptotic process GO:0097285 134 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
Rat
axis specification GO:0009798 4 0.012
protein maturation GO:0051604 68 0.012
formation of primary germ layer GO:0001704 1 0.012
dna integrity checkpoint GO:0031570 2 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
development of primary sexual characteristics GO:0045137 107 0.011
cation homeostasis GO:0055080 195 0.011
Rat
negative regulation of cell death GO:0060548 229 0.011
locomotion GO:0040011 237 0.011
Rat
regulation of neuron apoptotic process GO:0043523 83 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
embryonic skeletal system morphogenesis GO:0048704 3 0.011
sequestering of metal ion GO:0051238 9 0.011
regulation of cellular component organization GO:0051128 368 0.011
Rat
regulation of growth GO:0040008 105 0.011
monocarboxylic acid catabolic process GO:0072329 28 0.011
Rat
sodium independent organic anion transport GO:0043252 2 0.011
negative regulation of cell communication GO:0010648 158 0.011
Rat
protein oligomerization GO:0051259 191 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
signal release GO:0023061 145 0.011
Rat
anterior posterior pattern specification GO:0009952 1 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
Rat
carnitine transport GO:0015879 1 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
macroautophagy GO:0016236 4 0.011
embryo development GO:0009790 49 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
cellular response to acid chemical GO:0071229 75 0.011
c21 steroid hormone metabolic process GO:0008207 14 0.011
response to axon injury GO:0048678 59 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
regulation of blood volume by renal aldosterone GO:0002017 1 0.011
cardiac chamber development GO:0003205 1 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
chemotaxis GO:0006935 66 0.011
Rat
regulation of cell morphogenesis GO:0022604 77 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
Rat
response to insulin GO:0032868 133 0.010
regulation of signal transduction GO:0009966 318 0.010
Rat
organ morphogenesis GO:0009887 75 0.010
regulation of dendrite development GO:0050773 59 0.010
Rat
glucose homeostasis GO:0042593 75 0.010
neuron apoptotic process GO:0051402 88 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
Rat
monosaccharide transport GO:0015749 31 0.010
transmission of nerve impulse GO:0019226 42 0.010
Rat
negative regulation of muscle cell apoptotic process GO:0010656 21 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
response to radiation GO:0009314 137 0.010
nucleotide metabolic process GO:0009117 279 0.010
Rat
kidney development GO:0001822 67 0.010
negative regulation of gene expression GO:0010629 199 0.010
camp biosynthetic process GO:0006171 47 0.010
digestive tract development GO:0048565 39 0.010
heart development GO:0007507 72 0.010
sensory organ development GO:0007423 74 0.010

Lpar2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.029
inherited metabolic disorder DOID:655 0 0.026
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
congenital adrenal hyperplasia DOID:0050811 0 0.012
lipid metabolism disorder DOID:3146 0 0.012
steroid inherited metabolic disorder DOID:1701 0 0.012