Rattus norvegicus

69 known processes

Lrp2

low density lipoprotein-related protein 2

Lrp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.364
sodium ion transport GO:0006814 82 0.214
carboxylic acid metabolic process GO:0019752 289 0.183
organic acid metabolic process GO:0006082 292 0.162
cation transmembrane transport GO:0098655 263 0.147
nucleobase containing small molecule metabolic process GO:0055086 316 0.143
brain development GO:0007420 247 0.136
purine nucleotide metabolic process GO:0006163 229 0.134
ion transmembrane transport GO:0034220 365 0.133
monocarboxylic acid metabolic process GO:0032787 152 0.125
ribonucleotide metabolic process GO:0009259 231 0.120
head development GO:0060322 247 0.114
regulation of ion transport GO:0043269 245 0.113
protein complex assembly GO:0006461 263 0.107
neuron differentiation GO:0030182 368 0.102
homeostatic process GO:0042592 331 0.086
catabolic process GO:0009056 351 0.083
rna metabolic process GO:0016070 406 0.074
single organism catabolic process GO:0044712 283 0.071
inorganic ion transmembrane transport GO:0098660 229 0.070
organophosphate metabolic process GO:0019637 370 0.069
nucleotide metabolic process GO:0009117 279 0.066
positive regulation of transport GO:0051050 245 0.065
transcription dna templated GO:0006351 377 0.065
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.062
tissue development GO:0009888 252 0.060
anion transport GO:0006820 178 0.060
regulation of nucleic acid templated transcription GO:1903506 380 0.060
positive regulation of signaling GO:0023056 270 0.060
cell projection organization GO:0030030 302 0.059
regulation of multicellular organismal development GO:2000026 376 0.057
macromolecular complex assembly GO:0065003 273 0.057
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
protein localization GO:0008104 191 0.054
regulation of transcription dna templated GO:0006355 374 0.054
enzyme linked receptor protein signaling pathway GO:0007167 116 0.054
secretion GO:0046903 307 0.054
cellular catabolic process GO:0044248 295 0.053
rna biosynthetic process GO:0032774 380 0.053
aromatic compound catabolic process GO:0019439 168 0.052
purine containing compound metabolic process GO:0072521 253 0.052
cellular amine metabolic process GO:0044106 38 0.052
organ morphogenesis GO:0009887 75 0.051
transmembrane transport GO:0055085 412 0.051
positive regulation of molecular function GO:0044093 230 0.051
fatty acid metabolic process GO:0006631 99 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
nucleoside phosphate metabolic process GO:0006753 283 0.047
organonitrogen compound biosynthetic process GO:1901566 167 0.045
cellular component biogenesis GO:0044085 368 0.045
regulation of cellular component organization GO:0051128 368 0.044
cellular amino acid metabolic process GO:0006520 107 0.044
purine ribonucleotide metabolic process GO:0009150 227 0.044
macromolecular complex subunit organization GO:0043933 339 0.043
metanephric comma shaped body morphogenesis GO:0072278 2 0.042
organonitrogen compound catabolic process GO:1901565 179 0.042
regulation of molecular function GO:0065009 398 0.041
oligopeptide transport GO:0006857 4 0.041
heart morphogenesis GO:0003007 3 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.041
protein complex biogenesis GO:0070271 263 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.040
regulation of anatomical structure morphogenesis GO:0022603 141 0.040
glycosyl compound metabolic process GO:1901657 182 0.039
regulation of signal transduction GO:0009966 318 0.039
transcription from rna polymerase ii promoter GO:0006366 252 0.039
nucleic acid templated transcription GO:0097659 379 0.038
inorganic cation transmembrane transport GO:0098662 202 0.038
neuron development GO:0048666 286 0.037
purine ribonucleoside metabolic process GO:0046128 168 0.037
cell cell signaling GO:0007267 335 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.035
regulation of rna metabolic process GO:0051252 391 0.035
heterocycle catabolic process GO:0046700 167 0.035
purine nucleotide catabolic process GO:0006195 136 0.035
eye morphogenesis GO:0048592 4 0.035
protein complex subunit organization GO:0071822 302 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.034
ion homeostasis GO:0050801 212 0.034
ribonucleoside triphosphate metabolic process GO:0009199 141 0.033
regulation of cell differentiation GO:0045595 320 0.033
intracellular signal transduction GO:0035556 314 0.032
ribose phosphate metabolic process GO:0019693 235 0.032
regulation of rna biosynthetic process GO:2001141 381 0.032
regulation of cell morphogenesis GO:0022604 77 0.032
regulation of catabolic process GO:0009894 113 0.031
anatomical structure morphogenesis GO:0009653 298 0.031
organic substance catabolic process GO:1901575 316 0.031
cellular component morphogenesis GO:0032989 155 0.030
positive regulation of nucleotide metabolic process GO:0045981 91 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
purine nucleoside catabolic process GO:0006152 124 0.030
regulation of locomotion GO:0040012 148 0.030
cellular ketone metabolic process GO:0042180 51 0.030
response to inorganic substance GO:0010035 377 0.029
metal ion transport GO:0030001 289 0.029
organic cyclic compound catabolic process GO:1901361 175 0.029
vesicle mediated transport GO:0016192 181 0.029
multicellular organismal signaling GO:0035637 44 0.029
cellular component assembly GO:0022607 360 0.029
ribonucleoside metabolic process GO:0009119 174 0.029
organophosphate catabolic process GO:0046434 148 0.029
neuron projection development GO:0031175 273 0.028
synaptic growth at neuromuscular junction GO:0051124 1 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
negative regulation of metabolic process GO:0009892 331 0.028
coenzyme metabolic process GO:0006732 86 0.027
amine metabolic process GO:0009308 38 0.027
regulation of membrane potential GO:0042391 110 0.027
sodium ion transmembrane transport GO:0035725 67 0.027
male mating behavior GO:0060179 3 0.027
cellular nitrogen compound catabolic process GO:0044270 163 0.027
neurological system process GO:0050877 219 0.027
organic acid catabolic process GO:0016054 49 0.027
small gtpase mediated signal transduction GO:0007264 36 0.026
purine ribonucleoside catabolic process GO:0046130 124 0.026
single organism organelle organization GO:1902589 180 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
locomotion GO:0040011 237 0.026
nucleoside triphosphate catabolic process GO:0009143 123 0.025
protein autophosphorylation GO:0046777 66 0.025
oxidation reduction process GO:0055114 304 0.025
organic hydroxy compound metabolic process GO:1901615 115 0.025
aging GO:0007568 241 0.025
negative regulation of cell communication GO:0010648 158 0.025
alpha amino acid metabolic process GO:1901605 71 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
monovalent inorganic cation transport GO:0015672 172 0.025
regulation of neurogenesis GO:0050767 247 0.024
central nervous system development GO:0007417 311 0.024
response to oxidative stress GO:0006979 186 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
regulation of cell projection organization GO:0031344 175 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.024
sensory organ development GO:0007423 74 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
positive regulation of developmental process GO:0051094 283 0.024
developmental growth involved in morphogenesis GO:0060560 33 0.024
cation transport GO:0006812 382 0.024
organelle organization GO:0006996 266 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.024
carboxylic acid catabolic process GO:0046395 49 0.023
forebrain development GO:0030900 98 0.023
macromolecule localization GO:0033036 252 0.023
positive regulation of gene expression GO:0010628 244 0.023
axis specification GO:0009798 4 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
cell morphogenesis GO:0000902 142 0.023
purine ribonucleotide catabolic process GO:0009154 136 0.023
nucleoside phosphate catabolic process GO:1901292 140 0.023
nucleoside triphosphate metabolic process GO:0009141 144 0.022
gastrulation GO:0007369 2 0.022
regulation of neuron differentiation GO:0045664 208 0.022
metanephric s shaped body morphogenesis GO:0072284 2 0.022
cation homeostasis GO:0055080 195 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
positive regulation of immunoglobulin production GO:0002639 4 0.021
cytoskeleton organization GO:0007010 111 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
regulation of apoptotic process GO:0042981 335 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
retina morphogenesis in camera type eye GO:0060042 1 0.021
purine nucleoside triphosphate catabolic process GO:0009146 122 0.021
regulation of catalytic activity GO:0050790 304 0.021
retinal ganglion cell axon guidance GO:0031290 1 0.021
cofactor metabolic process GO:0051186 95 0.020
purine nucleoside triphosphate metabolic process GO:0009144 141 0.020
circadian rhythm GO:0007623 88 0.020
actin filament based process GO:0030029 86 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.020
ribonucleotide catabolic process GO:0009261 136 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
ribonucleoside triphosphate catabolic process GO:0009203 122 0.020
positive regulation of catabolic process GO:0009896 78 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
cell growth GO:0016049 104 0.019
neuron fate commitment GO:0048663 4 0.019
positive regulation of ion transport GO:0043270 94 0.019
small molecule catabolic process GO:0044282 59 0.019
small molecule biosynthetic process GO:0044283 124 0.019
single organism biosynthetic process GO:0044711 342 0.019
circulatory system process GO:0003013 183 0.019
ras protein signal transduction GO:0007265 29 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
negative regulation of signaling GO:0023057 157 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
purine containing compound catabolic process GO:0072523 138 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
anion transmembrane transport GO:0098656 77 0.018
regulation of transmembrane transport GO:0034762 122 0.018
insulin like growth factor receptor signaling pathway GO:0048009 3 0.018
regulation of hormone secretion GO:0046883 106 0.017
cellular lipid metabolic process GO:0044255 208 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
protein transport GO:0015031 132 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
blood circulation GO:0008015 183 0.017
antibiotic transport GO:0042891 2 0.017
response to peptide GO:1901652 292 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
regulation of secretion GO:0051046 224 0.017
chemical homeostasis GO:0048878 292 0.017
protein homooligomerization GO:0051260 91 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
protein oligomerization GO:0051259 191 0.016
lipid transport GO:0006869 61 0.016
programmed cell death GO:0012501 392 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
taxis GO:0042330 67 0.016
regulation of growth GO:0040008 105 0.016
regulation of nervous system development GO:0051960 264 0.016
cellular ion homeostasis GO:0006873 184 0.016
regulation of metal ion transport GO:0010959 118 0.016
response to metal ion GO:0010038 253 0.016
camera type eye morphogenesis GO:0048593 2 0.015
transmission of nerve impulse GO:0019226 42 0.015
cell cycle GO:0007049 101 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
nucleoside catabolic process GO:0009164 126 0.015
regulation of programmed cell death GO:0043067 341 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
nucleoside metabolic process GO:0009116 179 0.015
adult locomotory behavior GO:0008344 4 0.015
circadian regulation of gene expression GO:0032922 3 0.015
guanosine containing compound catabolic process GO:1901069 71 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
cellular response to stress GO:0033554 269 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
dephosphorylation GO:0016311 98 0.015
cardiac chamber development GO:0003205 1 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
synaptic transmission GO:0007268 235 0.014
regulation of gtpase activity GO:0043087 57 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
icosanoid metabolic process GO:0006690 38 0.014
response to toxic substance GO:0009636 133 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
cell projection morphogenesis GO:0048858 123 0.014
specification of organ identity GO:0010092 2 0.014
regulation of system process GO:0044057 208 0.014
amide transport GO:0042886 105 0.014
comma shaped body morphogenesis GO:0072049 2 0.013
chromosome segregation GO:0007059 2 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
response to peptide hormone GO:0043434 278 0.013
multicellular organism growth GO:0035264 1 0.013
neuronal action potential GO:0019228 35 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
action potential GO:0001508 54 0.013
fatty acid catabolic process GO:0009062 26 0.013
cell part morphogenesis GO:0032990 123 0.013
pyridine containing compound metabolic process GO:0072524 32 0.013
synaptic vesicle amine transport GO:0015842 3 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
response to glucocorticoid GO:0051384 223 0.013
regulation of cellular localization GO:0060341 263 0.013
divalent inorganic cation transport GO:0072511 134 0.013
developmental induction GO:0031128 2 0.013
nitrogen compound transport GO:0071705 229 0.013
nucleotide catabolic process GO:0009166 139 0.013
behavior GO:0007610 205 0.012
regulation of transferase activity GO:0051338 123 0.012
b cell differentiation GO:0030183 2 0.012
kidney morphogenesis GO:0060993 13 0.012
alkaloid metabolic process GO:0009820 3 0.012
regulation of nucleotide catabolic process GO:0030811 65 0.012
growth involved in heart morphogenesis GO:0003241 1 0.012
negative regulation of secretion GO:0051048 82 0.012
cellular homeostasis GO:0019725 252 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
spermatogenesis GO:0007283 99 0.012
embryonic pattern specification GO:0009880 1 0.012
negative regulation of transport GO:0051051 136 0.012
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.012
cell adhesion GO:0007155 110 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
protein phosphorylation GO:0006468 345 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
hormone transport GO:0009914 121 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
monocarboxylic acid catabolic process GO:0072329 28 0.011
intracellular transport GO:0046907 185 0.011
glutathione transport GO:0034635 2 0.011
astrocyte development GO:0014002 4 0.011
growth GO:0040007 165 0.011
neuron projection morphogenesis GO:0048812 122 0.011
positive regulation of gtp catabolic process GO:0033126 48 0.011
establishment of protein localization GO:0045184 141 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
single organism behavior GO:0044708 130 0.011
reproduction GO:0000003 245 0.011
epithelial cell differentiation GO:0030855 71 0.011
regulation of cell growth GO:0001558 85 0.011
regulation of cell proliferation GO:0042127 359 0.010
response to osmotic stress GO:0006970 42 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
purine nucleoside monophosphate metabolic process GO:0009126 84 0.010
negative regulation of cell death GO:0060548 229 0.010
heart development GO:0007507 72 0.010
positive regulation of calcium ion transport GO:0051928 36 0.010
cellular cation homeostasis GO:0030003 180 0.010
spindle organization GO:0007051 2 0.010
peptide secretion GO:0002790 86 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
tube development GO:0035295 89 0.010
sexual reproduction GO:0019953 148 0.010
positive regulation of cell communication GO:0010647 271 0.010
lipid metabolic process GO:0006629 283 0.010
regulation of hydrolase activity GO:0051336 143 0.010
regulation of protein modification process GO:0031399 194 0.010
regulation of homeostatic process GO:0032844 101 0.010
morphogenesis of embryonic epithelium GO:0016331 3 0.010
s shaped body morphogenesis GO:0072050 2 0.010
tripeptide transport GO:0042939 2 0.010

Lrp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
respiratory system disease DOID:1579 0 0.035
lower respiratory tract disease DOID:0050161 0 0.035
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.020
renal tubular transport disease DOID:447 0 0.011
kidney disease DOID:557 0 0.011
urinary system disease DOID:18 0 0.011