Rattus norvegicus

0 known processes

Lrrc50

leucine rich repeat containing 50

(Aliases: RGD1310542)

Lrrc50 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.268
carboxylic acid metabolic process GO:0019752 289 0.190
anatomical structure morphogenesis GO:0009653 298 0.186
Human Zebrafish
rhythmic process GO:0048511 156 0.153
oxoacid metabolic process GO:0043436 290 0.151
transcription dna templated GO:0006351 377 0.144
cell projection organization GO:0030030 302 0.134
Human Zebrafish
transcription from rna polymerase ii promoter GO:0006366 252 0.129
response to peptide GO:1901652 292 0.116
neuron development GO:0048666 286 0.097
apoptotic process GO:0006915 381 0.083
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.081
response to nutrient GO:0007584 248 0.081
organonitrogen compound biosynthetic process GO:1901566 167 0.080
transmembrane transport GO:0055085 412 0.078
single organism biosynthetic process GO:0044711 342 0.071
negative regulation of macromolecule metabolic process GO:0010605 260 0.070
regulation of molecular function GO:0065009 398 0.068
tissue development GO:0009888 252 0.068
Human Zebrafish
neuron differentiation GO:0030182 368 0.067
cell projection morphogenesis GO:0048858 123 0.065
Human Zebrafish
regulation of rna biosynthetic process GO:2001141 381 0.065
cell part morphogenesis GO:0032990 123 0.063
Human Zebrafish
macromolecular complex subunit organization GO:0043933 339 0.062
Human
regulation of nucleic acid templated transcription GO:1903506 380 0.060
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.060
negative regulation of metabolic process GO:0009892 331 0.060
cellular response to endogenous stimulus GO:0071495 377 0.057
cellular catabolic process GO:0044248 295 0.057
cellular component morphogenesis GO:0032989 155 0.056
Human Zebrafish
positive regulation of gene expression GO:0010628 244 0.055
response to peptide hormone GO:0043434 278 0.055
nucleic acid templated transcription GO:0097659 379 0.055
regulation of multicellular organismal development GO:2000026 376 0.054
amine metabolic process GO:0009308 38 0.053
cellular amino acid metabolic process GO:0006520 107 0.053
rna metabolic process GO:0016070 406 0.053
negative regulation of gene expression GO:0010629 199 0.051
metanephric s shaped body morphogenesis GO:0072284 2 0.050
head development GO:0060322 247 0.050
cellular amine metabolic process GO:0044106 38 0.050
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.049
positive regulation of response to stimulus GO:0048584 285 0.047
regulation of cell projection organization GO:0031344 175 0.045
monocarboxylic acid metabolic process GO:0032787 152 0.044
multicellular organism reproduction GO:0032504 233 0.043
reproduction GO:0000003 245 0.043
reproductive process GO:0022414 372 0.043
regulation of phosphate metabolic process GO:0019220 349 0.043
neuron projection morphogenesis GO:0048812 122 0.043
negative regulation of cellular biosynthetic process GO:0031327 161 0.041
response to glucose GO:0009749 136 0.041
central nervous system development GO:0007417 311 0.040
positive regulation of nucleic acid templated transcription GO:1903508 197 0.039
lipid biosynthetic process GO:0008610 128 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.039
ion transmembrane transport GO:0034220 365 0.038
cellular response to oxygen containing compound GO:1901701 386 0.038
developmental growth GO:0048589 100 0.037
organophosphate metabolic process GO:0019637 370 0.037
regulation of ion transmembrane transport GO:0034765 121 0.036
homeostatic process GO:0042592 331 0.035
response to cytokine GO:0034097 215 0.035
behavior GO:0007610 205 0.035
regulation of transcription dna templated GO:0006355 374 0.035
regulation of nucleotide metabolic process GO:0006140 117 0.035
regeneration GO:0031099 163 0.034
organ morphogenesis GO:0009887 75 0.034
Human Zebrafish
regulation of ion transport GO:0043269 245 0.034
regulation of neuron differentiation GO:0045664 208 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
response to nutrient levels GO:0031667 370 0.032
chemical homeostasis GO:0048878 292 0.032
positive regulation of rna biosynthetic process GO:1902680 197 0.032
response to hexose GO:0009746 144 0.032
chemosensory behavior GO:0007635 2 0.032
cellular lipid metabolic process GO:0044255 208 0.032
organonitrogen compound catabolic process GO:1901565 179 0.031
regulation of protein phosphorylation GO:0001932 183 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
regulation of cellular component organization GO:0051128 368 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.029
regulation of signal transduction GO:0009966 318 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
brain development GO:0007420 247 0.028
positive regulation of transport GO:0051050 245 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.028
regulation of transporter activity GO:0032409 50 0.028
cellular response to lipid GO:0071396 201 0.028
glycerolipid metabolic process GO:0046486 67 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
response to wounding GO:0009611 254 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
neuron projection development GO:0031175 273 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
negative regulation of nucleic acid templated transcription GO:1903507 117 0.027
response to other organism GO:0051707 220 0.027
s shaped body morphogenesis GO:0072050 2 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
single organism reproductive process GO:0044702 297 0.026
negative regulation of cell communication GO:0010648 158 0.026
protein complex subunit organization GO:0071822 302 0.026
Human
regulation of canonical wnt signaling pathway GO:0060828 4 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.025
organ formation GO:0048645 3 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
intracellular signal transduction GO:0035556 314 0.025
regulation of anatomical structure size GO:0090066 135 0.025
axon development GO:0061564 96 0.024
cation transmembrane transport GO:0098655 263 0.024
heart morphogenesis GO:0003007 3 0.024
Human Zebrafish
development of primary sexual characteristics GO:0045137 107 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
response to reactive oxygen species GO:0000302 120 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
gamete generation GO:0007276 124 0.024
cation transport GO:0006812 382 0.024
metanephric comma shaped body morphogenesis GO:0072278 2 0.023
sensory organ development GO:0007423 74 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
regulation of protein modification process GO:0031399 194 0.023
regulation of transmembrane transporter activity GO:0022898 49 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
cell morphogenesis GO:0000902 142 0.023
Human Zebrafish
positive regulation of transcription dna templated GO:0045893 197 0.023
sodium ion transmembrane transport GO:0035725 67 0.022
regulation of neuron projection development GO:0010975 161 0.022
regulation of rna metabolic process GO:0051252 391 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
regulation of cell development GO:0060284 263 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
sensory perception GO:0007600 101 0.022
regulation of system process GO:0044057 208 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
camera type eye development GO:0043010 48 0.022
mitotic spindle organization GO:0007052 2 0.022
cellular component assembly GO:0022607 360 0.021
Human Zebrafish
regulation of cell differentiation GO:0045595 320 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
response to extracellular stimulus GO:0009991 380 0.020
response to toxic substance GO:0009636 133 0.020
regulation of neurogenesis GO:0050767 247 0.020
single organism organelle organization GO:1902589 180 0.020
Human Zebrafish
circadian rhythm GO:0007623 88 0.020
response to carbohydrate GO:0009743 183 0.020
positive regulation of protein modification process GO:0031401 142 0.020
divalent inorganic cation homeostasis GO:0072507 165 0.020
regulation of apoptotic process GO:0042981 335 0.020
establishment of organelle localization GO:0051656 37 0.019
organic hydroxy compound metabolic process GO:1901615 115 0.019
retina development in camera type eye GO:0060041 27 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.019
divalent metal ion transport GO:0070838 132 0.019
regulation of programmed cell death GO:0043067 341 0.019
developmental induction GO:0031128 2 0.019
regulation of blood circulation GO:1903522 110 0.019
carbohydrate homeostasis GO:0033500 75 0.019
regulation of cellular localization GO:0060341 263 0.018
cellular ketone metabolic process GO:0042180 51 0.018
actin filament based process GO:0030029 86 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
anterior posterior pattern specification GO:0009952 1 0.018
synaptic growth at neuromuscular junction GO:0051124 1 0.018
organic acid biosynthetic process GO:0016053 83 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
myosin filament assembly GO:0031034 1 0.018
cellular chemical homeostasis GO:0055082 247 0.017
cellular response to insulin stimulus GO:0032869 81 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
positive regulation of developmental process GO:0051094 283 0.017
sexual reproduction GO:0019953 148 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
response to growth factor GO:0070848 189 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
gonad development GO:0008406 104 0.017
gland development GO:0048732 155 0.017
Human
spindle organization GO:0007051 2 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
response to fatty acid GO:0070542 65 0.017
axis specification GO:0009798 4 0.016
cardiac chamber development GO:0003205 1 0.016
regulation of catalytic activity GO:0050790 304 0.016
single organism behavior GO:0044708 130 0.016
growth GO:0040007 165 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
lipid metabolic process GO:0006629 283 0.016
regulation of tube size GO:0035150 89 0.016
cellular response to abiotic stimulus GO:0071214 85 0.016
comma shaped body morphogenesis GO:0072049 2 0.016
positive regulation of signaling GO:0023056 270 0.016
purine containing compound metabolic process GO:0072521 253 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
regulation of developmental growth GO:0048638 45 0.015
cellular response to acid chemical GO:0071229 75 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
positive regulation of the force of heart contraction by chemical signal GO:0003099 2 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
response to inorganic substance GO:0010035 377 0.015
heart contraction GO:0060047 57 0.015
regulation of mapk cascade GO:0043408 116 0.015
positive regulation of cell communication GO:0010647 271 0.015
reproductive structure development GO:0048608 128 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
positive regulation of organelle organization GO:0010638 48 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
negative regulation of nervous system development GO:0051961 79 0.015
embryonic skeletal system development GO:0048706 3 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.015
response to monosaccharide GO:0034284 159 0.015
organophosphate catabolic process GO:0046434 148 0.014
cellular response to monosaccharide stimulus GO:0071326 67 0.014
regulation of nervous system development GO:0051960 264 0.014
small molecule biosynthetic process GO:0044283 124 0.014
regulation of metal ion transport GO:0010959 118 0.014
male gamete generation GO:0048232 99 0.014
response to corticosteroid GO:0031960 235 0.014
heart process GO:0003015 57 0.014
cellular response to stress GO:0033554 269 0.014
protein complex assembly GO:0006461 263 0.014
Human
actin cytoskeleton organization GO:0030036 73 0.014
cellular response to hexose stimulus GO:0071331 65 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
multi organism reproductive process GO:0044703 262 0.014
eye morphogenesis GO:0048592 4 0.014
protein phosphorylation GO:0006468 345 0.014
regulation of heart contraction GO:0008016 48 0.014
regulation of cation channel activity GO:2001257 23 0.014
blood circulation GO:0008015 183 0.014
cell cell signaling involved in cell fate commitment GO:0045168 2 0.014
eye development GO:0001654 50 0.013
carboxylic acid biosynthetic process GO:0046394 83 0.013
response to estrogen GO:0043627 232 0.013
organelle organization GO:0006996 266 0.013
Human Zebrafish
cellular response to glucose stimulus GO:0071333 65 0.013
regulation of organ formation GO:0003156 2 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
vascular process in circulatory system GO:0003018 96 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
programmed cell death GO:0012501 392 0.013
protein oligomerization GO:0051259 191 0.013
nucleotide metabolic process GO:0009117 279 0.013
cellular component biogenesis GO:0044085 368 0.013
Human Zebrafish
rna biosynthetic process GO:0032774 380 0.012
lipid transport GO:0006869 61 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
glucose homeostasis GO:0042593 75 0.012
response to oxidative stress GO:0006979 186 0.012
regulation of catabolic process GO:0009894 113 0.012
cell cell signaling GO:0007267 335 0.012
spermatogenesis GO:0007283 99 0.012
negative regulation of molecular function GO:0044092 133 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
metanephric glomerulus development GO:0072224 3 0.012
developmental process involved in reproduction GO:0003006 159 0.012
negative regulation of cell development GO:0010721 82 0.012
cellular component movement GO:0006928 248 0.012
Human Zebrafish
wound healing GO:0042060 122 0.012
regulation of muscle system process GO:0090257 79 0.012
sex differentiation GO:0007548 113 0.012
regulation of cell proliferation GO:0042127 359 0.011
locomotor rhythm GO:0045475 1 0.011
cell fate determination GO:0001709 2 0.011
embryo development GO:0009790 49 0.011
Human Zebrafish
monocarboxylic acid biosynthetic process GO:0072330 48 0.011
regulation of membrane potential GO:0042391 110 0.011
negative regulation of dopamine secretion GO:0033602 4 0.011
alcohol metabolic process GO:0006066 77 0.011
positive regulation of potassium ion transmembrane transport GO:1901381 4 0.011
regulation of homotypic cell cell adhesion GO:0034110 4 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
regulation of hormone levels GO:0010817 187 0.011
olfactory behavior GO:0042048 2 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
peptide transport GO:0015833 97 0.011
forebrain development GO:0030900 98 0.011
regulation of transmembrane transport GO:0034762 122 0.011
response to antibiotic GO:0046677 39 0.011
regulation of cell fate commitment GO:0010453 1 0.010
cellular response to reactive oxygen species GO:0034614 55 0.010
synaptic vesicle endocytosis GO:0048488 4 0.010
regulation of metanephros development GO:0072215 4 0.010
cognition GO:0050890 92 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
cellular response to carbohydrate stimulus GO:0071322 72 0.010
sensory perception of light stimulus GO:0050953 3 0.010
metal ion transport GO:0030001 289 0.010
organic substance catabolic process GO:1901575 316 0.010
negative regulation of transport GO:0051051 136 0.010

Lrrc50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
primary ciliary dyskinesia DOID:9562 0 0.112
Human
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.031
nervous system disease DOID:863 0 0.026
muscular disease DOID:0080000 0 0.023
muscle tissue disease DOID:66 0 0.023
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
urinary system disease DOID:18 0 0.013
retinal disease DOID:5679 0 0.012
retinal degeneration DOID:8466 0 0.012
retinitis pigmentosa DOID:10584 0 0.012