Rattus norvegicus

0 known processes

Lrrc59

leucine rich repeat containing 59

(Aliases: MGC105677)

Lrrc59 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular biogenic amine biosynthetic process GO:0042401 4 0.276
polyamine biosynthetic process GO:0006596 4 0.238
macromolecular complex assembly GO:0065003 273 0.208
regulation of nucleic acid templated transcription GO:1903506 380 0.183
regulation of immune system process GO:0002682 123 0.162
rna metabolic process GO:0016070 406 0.155
positive regulation of biosynthetic process GO:0009891 319 0.146
rna biosynthetic process GO:0032774 380 0.129
organelle organization GO:0006996 266 0.123
nucleic acid templated transcription GO:0097659 379 0.122
brain development GO:0007420 247 0.107
regulation of molecular function GO:0065009 398 0.100
positive regulation of cellular biosynthetic process GO:0031328 295 0.098
positive regulation of gene expression GO:0010628 244 0.098
response to external biotic stimulus GO:0043207 221 0.096
regulation of rna metabolic process GO:0051252 391 0.095
immune system process GO:0002376 204 0.092
negative regulation of gene expression GO:0010629 199 0.090
negative regulation of developmental process GO:0051093 125 0.088
reproductive process GO:0022414 372 0.087
protein complex subunit organization GO:0071822 302 0.084
regulation of cellular protein metabolic process GO:0032268 267 0.081
regulation of cellular component organization GO:0051128 368 0.081
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.074
negative regulation of macromolecule metabolic process GO:0010605 260 0.073
metal ion homeostasis GO:0055065 186 0.073
regulation of rna biosynthetic process GO:2001141 381 0.073
positive regulation of apoptotic process GO:0043065 154 0.070
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.069
regulation of programmed cell death GO:0043067 341 0.069
cellular component assembly GO:0022607 360 0.069
vesicle mediated transport GO:0016192 181 0.067
neural crest cell development GO:0014032 2 0.066
intracellular transport GO:0046907 185 0.065
eye morphogenesis GO:0048592 4 0.064
single organism organelle organization GO:1902589 180 0.064
catabolic process GO:0009056 351 0.063
cellular ion homeostasis GO:0006873 184 0.061
cytoskeleton organization GO:0007010 111 0.061
aging GO:0007568 241 0.060
single organism reproductive process GO:0044702 297 0.060
positive regulation of phosphorus metabolic process GO:0010562 262 0.060
cellular response to stress GO:0033554 269 0.060
regulation of transcription dna templated GO:0006355 374 0.058
proteolysis GO:0006508 175 0.058
er associated ubiquitin dependent protein catabolic process GO:0030433 1 0.057
gland development GO:0048732 155 0.056
head development GO:0060322 247 0.056
amine metabolic process GO:0009308 38 0.056
cellular component biogenesis GO:0044085 368 0.054
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.054
cation homeostasis GO:0055080 195 0.054
reproduction GO:0000003 245 0.054
negative regulation of cellular biosynthetic process GO:0031327 161 0.054
cytoplasmic transport GO:0016482 115 0.051
alpha amino acid metabolic process GO:1901605 71 0.051
regulation of neurogenesis GO:0050767 247 0.051
positive regulation of nucleic acid templated transcription GO:1903508 197 0.050
neuron projection development GO:0031175 273 0.050
protein complex assembly GO:0006461 263 0.049
regulation of cell proliferation GO:0042127 359 0.048
negative regulation of cell development GO:0010721 82 0.048
negative regulation of metabolic process GO:0009892 331 0.047
endoplasmic reticulum unfolded protein response GO:0030968 2 0.047
tissue development GO:0009888 252 0.046
hepaticobiliary system development GO:0061008 90 0.046
regulation of leukocyte migration GO:0002685 24 0.045
organic acid metabolic process GO:0006082 292 0.044
cellular amino acid metabolic process GO:0006520 107 0.044
ribose phosphate metabolic process GO:0019693 235 0.044
regulation of cell differentiation GO:0045595 320 0.043
apoptotic process GO:0006915 381 0.043
negative regulation of multicellular organismal process GO:0051241 203 0.043
carbohydrate derivative biosynthetic process GO:1901137 124 0.043
programmed cell death GO:0012501 392 0.043
positive regulation of rna metabolic process GO:0051254 203 0.042
regulation of transmembrane transport GO:0034762 122 0.042
protein complex biogenesis GO:0070271 263 0.041
macromolecule localization GO:0033036 252 0.041
negative regulation of biosynthetic process GO:0009890 168 0.040
cellular chemical homeostasis GO:0055082 247 0.040
cellular metal ion homeostasis GO:0006875 172 0.039
neuron differentiation GO:0030182 368 0.039
receptor mediated endocytosis GO:0006898 42 0.039
intracellular signal transduction GO:0035556 314 0.039
regulation of behavior GO:0050795 61 0.038
organonitrogen compound biosynthetic process GO:1901566 167 0.038
positive regulation of cell differentiation GO:0045597 217 0.038
regulation of calcium ion transport GO:0051924 77 0.037
anatomical structure morphogenesis GO:0009653 298 0.037
regulation of ion transport GO:0043269 245 0.036
calcium ion transport GO:0006816 131 0.035
nucleotide metabolic process GO:0009117 279 0.035
positive regulation of phosphate metabolic process GO:0045937 262 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
membrane organization GO:0061024 94 0.035
negative regulation of cell differentiation GO:0045596 99 0.034
regulation of cellular component biogenesis GO:0044087 86 0.034
secretion by cell GO:0032940 248 0.034
central nervous system development GO:0007417 311 0.034
cellular response to unfolded protein GO:0034620 2 0.033
regulation of phosphate metabolic process GO:0019220 349 0.033
oxoacid metabolic process GO:0043436 290 0.033
macromolecule catabolic process GO:0009057 58 0.033
response to hypoxia GO:0001666 231 0.032
cellular amine metabolic process GO:0044106 38 0.032
mitotic cell cycle GO:0000278 49 0.032
sexual reproduction GO:0019953 148 0.031
regulation of multicellular organismal development GO:2000026 376 0.031
positive regulation of rna biosynthetic process GO:1902680 197 0.031
single organism intracellular transport GO:1902582 166 0.031
neuron development GO:0048666 286 0.030
positive regulation of catalytic activity GO:0043085 184 0.030
cardiovascular system development GO:0072358 134 0.029
negative regulation of dendrite development GO:2000171 9 0.029
multicellular organism reproduction GO:0032504 233 0.029
homeostatic process GO:0042592 331 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
synaptic vesicle endocytosis GO:0048488 4 0.028
cellular cation homeostasis GO:0030003 180 0.028
cell cycle GO:0007049 101 0.027
maintenance of location GO:0051235 17 0.027
chemical homeostasis GO:0048878 292 0.027
cation transport GO:0006812 382 0.026
cellular homeostasis GO:0019725 252 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
chromatin remodeling GO:0006338 3 0.025
response to endoplasmic reticulum stress GO:0034976 10 0.025
positive regulation of cell migration GO:0030335 96 0.025
regulation of response to stress GO:0080134 126 0.024
dna metabolic process GO:0006259 96 0.024
organophosphate metabolic process GO:0019637 370 0.024
cellular response to cytokine stimulus GO:0071345 127 0.024
carboxylic acid biosynthetic process GO:0046394 83 0.024
protein polymerization GO:0051258 22 0.024
endocytosis GO:0006897 84 0.024
regulation of hydrolase activity GO:0051336 143 0.024
regulation of metal ion transport GO:0010959 118 0.024
protein localization to organelle GO:0033365 57 0.024
organelle localization GO:0051640 55 0.023
negative regulation of rna biosynthetic process GO:1902679 118 0.023
extracellular matrix constituent secretion GO:0070278 4 0.023
response to decreased oxygen levels GO:0036293 237 0.023
inorganic cation transmembrane transport GO:0098662 202 0.023
positive regulation of cell death GO:0010942 184 0.023
positive regulation of immune system process GO:0002684 90 0.023
positive regulation of cellular component biogenesis GO:0044089 55 0.023
gamete generation GO:0007276 124 0.022
cellular protein complex assembly GO:0043623 44 0.022
positive regulation of hydrolase activity GO:0051345 86 0.022
response to other organism GO:0051707 220 0.022
divalent metal ion transport GO:0070838 132 0.022
chromosome segregation GO:0007059 2 0.022
regulation of cell cycle GO:0051726 73 0.022
membrane fusion GO:0061025 26 0.022
nucleocytoplasmic transport GO:0006913 48 0.022
defense response GO:0006952 194 0.022
response to cytokine GO:0034097 215 0.022
positive regulation of programmed cell death GO:0043068 157 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
multi organism reproductive process GO:0044703 262 0.021
positive regulation of transcription dna templated GO:0045893 197 0.021
carboxylic acid metabolic process GO:0019752 289 0.020
cytoskeleton dependent cytokinesis GO:0061640 2 0.020
developmental process involved in reproduction GO:0003006 159 0.020
divalent inorganic cation transport GO:0072511 134 0.020
establishment of protein localization GO:0045184 141 0.020
positive regulation of organelle organization GO:0010638 48 0.020
positive regulation of molecular function GO:0044093 230 0.020
regulation of cell development GO:0060284 263 0.020
response to amine GO:0014075 46 0.020
positive regulation of developmental process GO:0051094 283 0.020
ion homeostasis GO:0050801 212 0.019
negative regulation of nervous system development GO:0051961 79 0.019
cell morphogenesis involved in differentiation GO:0000904 119 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
regulation of catabolic process GO:0009894 113 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
cellular biogenic amine metabolic process GO:0006576 30 0.019
lipid storage GO:0019915 1 0.018
cellular catabolic process GO:0044248 295 0.018
vesicle docking GO:0048278 5 0.018
response to oxidative stress GO:0006979 186 0.018
cellular component movement GO:0006928 248 0.018
regulation of catalytic activity GO:0050790 304 0.018
response to peptide hormone GO:0043434 278 0.018
regulation of anatomical structure size GO:0090066 135 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.018
regulation of cell cycle process GO:0010564 31 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
sequestering of metal ion GO:0051238 9 0.018
positive regulation of protein metabolic process GO:0051247 178 0.017
regulation of protein metabolic process GO:0051246 289 0.017
nicotinamide nucleotide metabolic process GO:0046496 28 0.017
er nucleus signaling pathway GO:0006984 3 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
secretion GO:0046903 307 0.016
spermatogenesis GO:0007283 99 0.016
regulation of nervous system development GO:0051960 264 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
eye development GO:0001654 50 0.016
vesicle docking involved in exocytosis GO:0006904 4 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
single organism membrane organization GO:0044802 74 0.015
response to tumor cell GO:0002347 4 0.015
ras protein signal transduction GO:0007265 29 0.015
single organism biosynthetic process GO:0044711 342 0.015
nitrogen compound transport GO:0071705 229 0.015
heterocycle catabolic process GO:0046700 167 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
response to oxygen levels GO:0070482 265 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
reproductive structure development GO:0048608 128 0.014
protein modification by small protein conjugation GO:0032446 31 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
cellular response to oxidative stress GO:0034599 76 0.014
protein modification by small protein conjugation or removal GO:0070647 35 0.014
glycoprotein biosynthetic process GO:0009101 19 0.014
regulation of calcium ion transmembrane transporter activity GO:1901019 17 0.014
spindle organization GO:0007051 2 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
nuclear import GO:0051170 35 0.014
sex differentiation GO:0007548 113 0.014
cellular response to external stimulus GO:0071496 118 0.014
protein targeting to nucleus GO:0044744 35 0.014
anterograde axon cargo transport GO:0008089 1 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
regulation of neuron differentiation GO:0045664 208 0.014
response to inorganic substance GO:0010035 377 0.014
cardiac ventricle development GO:0003231 1 0.014
negative regulation of rna metabolic process GO:0051253 123 0.013
regulation of locomotion GO:0040012 148 0.013
response to nutrient levels GO:0031667 370 0.013
protein import into nucleus GO:0006606 35 0.013
cell cycle process GO:0022402 57 0.013
single organism catabolic process GO:0044712 283 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
male gamete generation GO:0048232 99 0.013
microtubule organizing center organization GO:0031023 1 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
nuclear transport GO:0051169 49 0.013
organic anion transport GO:0015711 132 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
endoplasmic reticulum organization GO:0007029 1 0.013
liver development GO:0001889 90 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
tube development GO:0035295 89 0.012
transcription dna templated GO:0006351 377 0.012
positive regulation of cell motility GO:2000147 97 0.012
calcium ion transport into cytosol GO:0060402 38 0.012
calcium ion homeostasis GO:0055074 162 0.012
protein catabolic process GO:0030163 30 0.012
locomotion GO:0040011 237 0.012
regulation of chemotaxis GO:0050920 29 0.012
sequestering of calcium ion GO:0051208 8 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
maintenance of protein location GO:0045185 7 0.012
lipid localization GO:0010876 62 0.012
regulation of apoptotic process GO:0042981 335 0.012
dephosphorylation GO:0016311 98 0.012
response to wounding GO:0009611 254 0.012
cell migration GO:0016477 197 0.012
oxidation reduction process GO:0055114 304 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
chromatin assembly or disassembly GO:0006333 1 0.012
immune effector process GO:0002252 53 0.012
coenzyme metabolic process GO:0006732 86 0.012
rna localization GO:0006403 4 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
reproductive system development GO:0061458 128 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.011
calcium ion transmembrane transport GO:0070588 70 0.011
protein folding GO:0006457 12 0.011
negative regulation of molecular function GO:0044092 133 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
camera type eye morphogenesis GO:0048593 2 0.011
immune response GO:0006955 104 0.011
regulation of neuron projection development GO:0010975 161 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
multicellular organism growth GO:0035264 1 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
embryo development GO:0009790 49 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
response to glucose GO:0009749 136 0.011
innate immune response GO:0045087 35 0.011
metal ion transport GO:0030001 289 0.011
gtp metabolic process GO:0046039 72 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
negative regulation of cell death GO:0060548 229 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
regulation of signal transduction GO:0009966 318 0.011
cellular response to nutrient levels GO:0031669 60 0.011
synaptic transmission GO:0007268 235 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
proteasomal protein catabolic process GO:0010498 8 0.010
amine biosynthetic process GO:0009309 4 0.010
branched chain amino acid transport GO:0015803 2 0.010
regulation of cell projection organization GO:0031344 175 0.010
cell projection organization GO:0030030 302 0.010
chordate embryonic development GO:0043009 18 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.010

Lrrc59 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
neuromuscular disease DOID:440 0 0.021
charcot marie tooth disease type 2 DOID:0050539 0 0.021
charcot marie tooth disease DOID:10595 0 0.021
neuropathy DOID:870 0 0.021
central nervous system disease DOID:331 0 0.016
brain disease DOID:936 0 0.014
disease of cellular proliferation DOID:14566 0 0.010