Rattus norvegicus

25 known processes

Lss

lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)

Lss biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid biosynthetic process GO:0008610 128 0.971
lipid metabolic process GO:0006629 283 0.901
cholesterol metabolic process GO:0008203 17 0.788
small molecule biosynthetic process GO:0044283 124 0.744
sterol metabolic process GO:0016125 18 0.739
fatty acid biosynthetic process GO:0006633 33 0.712
cellular lipid metabolic process GO:0044255 208 0.692
monocarboxylic acid biosynthetic process GO:0072330 48 0.574
acetyl coa metabolic process GO:0006084 17 0.526
alcohol metabolic process GO:0006066 77 0.514
single organism biosynthetic process GO:0044711 342 0.499
coenzyme metabolic process GO:0006732 86 0.401
steroid biosynthetic process GO:0006694 48 0.371
alcohol biosynthetic process GO:0046165 38 0.316
organic hydroxy compound metabolic process GO:1901615 115 0.296
monocarboxylic acid metabolic process GO:0032787 152 0.281
steroid metabolic process GO:0008202 73 0.263
cofactor metabolic process GO:0051186 95 0.169
carboxylic acid biosynthetic process GO:0046394 83 0.166
cellular response to oxygen containing compound GO:1901701 386 0.154
organic hydroxy compound biosynthetic process GO:1901617 51 0.142
response to starvation GO:0042594 59 0.132
cellular response to nitrogen compound GO:1901699 210 0.122
regulation of lipid biosynthetic process GO:0046890 38 0.119
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.116
response to peptide GO:1901652 292 0.109
fatty acid metabolic process GO:0006631 99 0.107
organic acid metabolic process GO:0006082 292 0.104
regulation of hormone levels GO:0010817 187 0.103
cellular response to peptide hormone stimulus GO:0071375 120 0.102
secretion GO:0046903 307 0.100
carboxylic acid metabolic process GO:0019752 289 0.095
regulation of cholesterol metabolic process GO:0090181 5 0.093
response to insulin GO:0032868 133 0.091
regulation of lipid metabolic process GO:0019216 68 0.089
cellular response to lipid GO:0071396 201 0.084
oxoacid metabolic process GO:0043436 290 0.081
isoprenoid metabolic process GO:0006720 45 0.080
response to nutrient levels GO:0031667 370 0.079
response to peptide hormone GO:0043434 278 0.076
response to nutrient GO:0007584 248 0.072
organic acid biosynthetic process GO:0016053 83 0.070
response to extracellular stimulus GO:0009991 380 0.066
phospholipid metabolic process GO:0006644 61 0.064
transmembrane transport GO:0055085 412 0.064
response to isolation stress GO:0035900 2 0.063
cellular response to organonitrogen compound GO:0071417 197 0.059
metanephric epithelium development GO:0072207 4 0.058
regulation of secretion GO:0051046 224 0.056
organophosphate metabolic process GO:0019637 370 0.053
response to other organism GO:0051707 220 0.052
response to fatty acid GO:0070542 65 0.052
anion transport GO:0006820 178 0.051
acyl coa metabolic process GO:0006637 28 0.051
organophosphate biosynthetic process GO:0090407 143 0.050
regulation of homeostatic process GO:0032844 101 0.045
regulation of phosphate metabolic process GO:0019220 349 0.043
cellular response to hormone stimulus GO:0032870 247 0.041
positive regulation of transport GO:0051050 245 0.041
metanephric tubule development GO:0072170 4 0.040
negative regulation of cell communication GO:0010648 158 0.040
regulation of triglyceride biosynthetic process GO:0010866 4 0.037
response to biotic stimulus GO:0009607 226 0.037
regulation of cellular amine metabolic process GO:0033238 8 0.037
brain development GO:0007420 247 0.037
regulation of cell proliferation GO:0042127 359 0.036
cellular amine metabolic process GO:0044106 38 0.036
sterol biosynthetic process GO:0016126 10 0.036
ribose phosphate metabolic process GO:0019693 235 0.035
cellular response to endogenous stimulus GO:0071495 377 0.034
organic anion transport GO:0015711 132 0.033
aging GO:0007568 241 0.033
response to external biotic stimulus GO:0043207 221 0.033
cellular response to peptide GO:1901653 133 0.033
gonad development GO:0008406 104 0.032
vesicle mediated transport GO:0016192 181 0.032
cholesterol biosynthetic process GO:0006695 10 0.031
plasma lipoprotein particle clearance GO:0034381 3 0.031
icosanoid metabolic process GO:0006690 38 0.030
acetate metabolic process GO:0006083 2 0.030
positive regulation of cell growth GO:0030307 44 0.030
secretion by cell GO:0032940 248 0.029
response to ethanol GO:0045471 162 0.029
thioester metabolic process GO:0035383 28 0.029
response to cytokine GO:0034097 215 0.029
amine metabolic process GO:0009308 38 0.028
cellular response to stress GO:0033554 269 0.028
positive regulation of cell communication GO:0010647 271 0.028
response to ketone GO:1901654 182 0.028
cell projection organization GO:0030030 302 0.028
response to acid chemical GO:0001101 222 0.027
organelle organization GO:0006996 266 0.027
carboxylic acid transport GO:0046942 115 0.027
sterol homeostasis GO:0055092 3 0.027
regulation of cellular component organization GO:0051128 368 0.027
head development GO:0060322 247 0.027
cellular ion homeostasis GO:0006873 184 0.027
cellular component assembly GO:0022607 360 0.026
regulation of cellular localization GO:0060341 263 0.026
male mating behavior GO:0060179 3 0.026
macromolecular complex assembly GO:0065003 273 0.025
oxidation reduction process GO:0055114 304 0.025
chemical homeostasis GO:0048878 292 0.025
cell cell signaling GO:0007267 335 0.025
endocytosis GO:0006897 84 0.024
positive regulation of secretion by cell GO:1903532 128 0.024
homeostatic process GO:0042592 331 0.024
ras protein signal transduction GO:0007265 29 0.023
regulation of secretion by cell GO:1903530 208 0.023
central nervous system development GO:0007417 311 0.023
regulation of cell morphogenesis GO:0022604 77 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
regulation of cholesterol biosynthetic process GO:0045540 4 0.023
cellular component biogenesis GO:0044085 368 0.023
cellular chemical homeostasis GO:0055082 247 0.023
hormone transport GO:0009914 121 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
multicellular organism reproduction GO:0032504 233 0.022
cellular ketone metabolic process GO:0042180 51 0.022
intracellular signal transduction GO:0035556 314 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
response to inorganic substance GO:0010035 377 0.022
response to carbohydrate GO:0009743 183 0.022
nitrogen compound transport GO:0071705 229 0.022
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.022
macromolecule localization GO:0033036 252 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.021
signal release GO:0023061 145 0.021
single organism intracellular transport GO:1902582 166 0.021
triglyceride metabolic process GO:0006641 21 0.021
proteolysis GO:0006508 175 0.021
unsaturated fatty acid metabolic process GO:0033559 39 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
cellular cation homeostasis GO:0030003 180 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
cellular catabolic process GO:0044248 295 0.021
positive regulation of triglyceride metabolic process GO:0090208 4 0.020
cellular response to cytokine stimulus GO:0071345 127 0.020
organophosphate catabolic process GO:0046434 148 0.020
response to estrogen GO:0043627 232 0.020
positive regulation of signaling GO:0023056 270 0.020
cellular response to insulin stimulus GO:0032869 81 0.019
single organism catabolic process GO:0044712 283 0.019
positive regulation of cardiac muscle cell apoptotic process GO:0010666 3 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
catabolic process GO:0009056 351 0.019
cell morphogenesis GO:0000902 142 0.019
response to corticosteroid GO:0031960 235 0.018
cellular response to extracellular stimulus GO:0031668 73 0.018
organic substance catabolic process GO:1901575 316 0.018
regulation of response to external stimulus GO:0032101 106 0.018
response to bacterium GO:0009617 200 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
multicellular organism growth GO:0035264 1 0.018
multi multicellular organism process GO:0044706 138 0.018
tube development GO:0035295 89 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
hepaticobiliary system development GO:0061008 90 0.018
circulatory system development GO:0072359 134 0.018
response to glucose GO:0009749 136 0.018
ion transmembrane transport GO:0034220 365 0.017
response to purine containing compound GO:0014074 126 0.017
embryonic skeletal system development GO:0048706 3 0.017
response to lipopolysaccharide GO:0032496 191 0.017
response to decreased oxygen levels GO:0036293 237 0.017
single organism reproductive process GO:0044702 297 0.017
lipid localization GO:0010876 62 0.017
response to interleukin 1 GO:0070555 55 0.017
regulation of hormone secretion GO:0046883 106 0.017
multi organism reproductive process GO:0044703 262 0.017
peptide secretion GO:0002790 86 0.016
gland development GO:0048732 155 0.016
regulation of plasma lipoprotein particle levels GO:0097006 3 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.016
reproductive structure development GO:0048608 128 0.016
positive regulation of secretion GO:0051047 140 0.016
short chain fatty acid metabolic process GO:0046459 3 0.015
cellular response to acid chemical GO:0071229 75 0.015
regulation of catalytic activity GO:0050790 304 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
single organism organelle organization GO:1902589 180 0.015
response to organophosphorus GO:0046683 102 0.015
carbohydrate homeostasis GO:0033500 75 0.015
cytoskeleton organization GO:0007010 111 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
regulation of cell growth GO:0001558 85 0.015
cell adhesion GO:0007155 110 0.015
acute inflammatory response GO:0002526 58 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
neurological system process GO:0050877 219 0.014
inflammatory response GO:0006954 150 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
sulfur compound metabolic process GO:0006790 70 0.014
cellular response to fatty acid GO:0071398 29 0.014
response to monosaccharide GO:0034284 159 0.014
cellular response to molecule of bacterial origin GO:0071219 56 0.014
regulation of protein metabolic process GO:0051246 289 0.014
gamete generation GO:0007276 124 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
blood circulation GO:0008015 183 0.014
intracellular transport GO:0046907 185 0.014
neuron projection development GO:0031175 273 0.014
negative regulation of metabolic process GO:0009892 331 0.014
cholesterol homeostasis GO:0042632 3 0.014
regulation of membrane potential GO:0042391 110 0.014
peptide transport GO:0015833 97 0.014
liver development GO:0001889 90 0.014
amide transport GO:0042886 105 0.014
regulation of catabolic process GO:0009894 113 0.014
negative regulation of transport GO:0051051 136 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
negative regulation of signaling GO:0023057 157 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
defense response GO:0006952 194 0.013
response to oxygen levels GO:0070482 265 0.013
regulation of peptide transport GO:0090087 87 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
protein maturation GO:0051604 68 0.013
cellular homeostasis GO:0019725 252 0.013
peptide hormone secretion GO:0030072 84 0.013
regulation of cell motility GO:2000145 131 0.013
reproductive process GO:0022414 372 0.013
intestinal absorption GO:0050892 3 0.013
metal ion homeostasis GO:0055065 186 0.013
unsaturated fatty acid biosynthetic process GO:0006636 21 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
protein complex subunit organization GO:0071822 302 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
positive regulation of protein modification process GO:0031401 142 0.013
muscle cell proliferation GO:0033002 84 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
response to vitamin GO:0033273 131 0.013
single organism behavior GO:0044708 130 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
neuron development GO:0048666 286 0.013
protein complex assembly GO:0006461 263 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
response to hexose GO:0009746 144 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
organic acid transport GO:0015849 116 0.012
hormone metabolic process GO:0042445 69 0.012
protein oligomerization GO:0051259 191 0.012
negative regulation of cell death GO:0060548 229 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
programmed cell death GO:0012501 392 0.012
behavior GO:0007610 205 0.012
regulation of neuron projection development GO:0010975 161 0.012
regulation of molecular function GO:0065009 398 0.012
negative regulation of gene expression GO:0010629 199 0.012
developmental growth GO:0048589 100 0.012
lipid storage GO:0019915 1 0.012
regulation of cell differentiation GO:0045595 320 0.012
ethanolamine containing compound metabolic process GO:0042439 14 0.012
phospholipid biosynthetic process GO:0008654 29 0.012
response to metal ion GO:0010038 253 0.012
regulation of steroid metabolic process GO:0019218 25 0.012
actin filament based process GO:0030029 86 0.012
protein complex biogenesis GO:0070271 263 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
positive regulation of molecular function GO:0044093 230 0.012
macromolecular complex subunit organization GO:0043933 339 0.011
regulation of multicellular organismal development GO:2000026 376 0.011
regulation of response to wounding GO:1903034 69 0.011
regulation of developmental growth GO:0048638 45 0.011
cellular component movement GO:0006928 248 0.011
glucose homeostasis GO:0042593 75 0.011
positive regulation of skeletal muscle tissue development GO:0048643 4 0.011
sensory perception GO:0007600 101 0.011
regulation of alcohol biosynthetic process GO:1902930 12 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
neutral lipid biosynthetic process GO:0046460 7 0.011
regulation of peptide secretion GO:0002791 82 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
ion homeostasis GO:0050801 212 0.011
axis specification GO:0009798 4 0.011
neuron differentiation GO:0030182 368 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
cation transport GO:0006812 382 0.011
positive regulation of lipid biosynthetic process GO:0046889 25 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
response to estradiol GO:0032355 164 0.011
spindle organization GO:0007051 2 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
response to wounding GO:0009611 254 0.010
male gamete generation GO:0048232 99 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
negative regulation of molecular function GO:0044092 133 0.010
purine containing compound metabolic process GO:0072521 253 0.010
cellular response to external stimulus GO:0071496 118 0.010
positive regulation of cell differentiation GO:0045597 217 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
cellular response to nutrient levels GO:0031669 60 0.010
response to testosterone GO:0033574 55 0.010
response to hypoxia GO:0001666 231 0.010
heart morphogenesis GO:0003007 3 0.010
spermatogenesis GO:0007283 99 0.010
regulation of rna biosynthetic process GO:2001141 381 0.010
regulation of signal transduction GO:0009966 318 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010

Lss disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.018
disease of anatomical entity DOID:7 0 0.018
inherited metabolic disorder DOID:655 0 0.016
disease of metabolism DOID:0014667 0 0.016
sensory system disease DOID:0050155 0 0.012