Rattus norvegicus

0 known processes

Magi1

membrane associated guanylate kinase, WW and PDZ domain containing 1

Magi1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling GO:0007267 335 0.494
ion homeostasis GO:0050801 212 0.414
synaptic vesicle exocytosis GO:0016079 15 0.387
exocytosis GO:0006887 60 0.334
synaptic transmission GO:0007268 235 0.323
synaptic vesicle endocytosis GO:0048488 4 0.311
secretion GO:0046903 307 0.231
protein heterooligomerization GO:0051291 89 0.214
signal release GO:0023061 145 0.208
receptor localization to synapse GO:0097120 2 0.202
synaptic vesicle transport GO:0048489 23 0.193
regulation of secretion by cell GO:1903530 208 0.188
regulation of exocytosis GO:0017157 37 0.167
macromolecular complex assembly GO:0065003 273 0.165
neurotransmitter secretion GO:0007269 33 0.163
neuron development GO:0048666 286 0.158
protein complex subunit organization GO:0071822 302 0.158
regulation of cell development GO:0060284 263 0.148
calcium ion homeostasis GO:0055074 162 0.146
cellular chemical homeostasis GO:0055082 247 0.141
positive regulation of locomotion GO:0040017 102 0.137
cellular calcium ion homeostasis GO:0006874 160 0.136
regulation of synaptic transmission GO:0050804 141 0.131
positive regulation of exocytosis GO:0045921 19 0.131
synaptic vesicle localization GO:0097479 24 0.126
inorganic ion transmembrane transport GO:0098660 229 0.123
regulation of membrane potential GO:0042391 110 0.121
chemical homeostasis GO:0048878 292 0.118
positive regulation of multicellular organismal process GO:0051240 387 0.116
positive regulation of cellular component organization GO:0051130 200 0.110
regulation of synaptic vesicle exocytosis GO:2000300 6 0.106
cellular component assembly GO:0022607 360 0.105
metal ion homeostasis GO:0055065 186 0.103
positive regulation of developmental process GO:0051094 283 0.103
homeostatic process GO:0042592 331 0.101
intracellular signal transduction GO:0035556 314 0.100
secretion by cell GO:0032940 248 0.097
cellular ion homeostasis GO:0006873 184 0.092
hormone secretion GO:0046879 115 0.092
vesicle localization GO:0051648 33 0.092
rhythmic synaptic transmission GO:0060024 1 0.091
biological adhesion GO:0022610 110 0.091
regulation of cell differentiation GO:0045595 320 0.090
immune response GO:0006955 104 0.087
cellular cation homeostasis GO:0030003 180 0.087
cytosolic calcium ion homeostasis GO:0051480 140 0.086
lipid metabolic process GO:0006629 283 0.083
establishment of organelle localization GO:0051656 37 0.082
protein complex biogenesis GO:0070271 263 0.081
organic hydroxy compound metabolic process GO:1901615 115 0.078
cellular homeostasis GO:0019725 252 0.074
locomotion GO:0040011 237 0.072
cellular divalent inorganic cation homeostasis GO:0072503 162 0.071
neurological system process GO:0050877 219 0.071
regulation of cellular localization GO:0060341 263 0.070
positive regulation of transport GO:0051050 245 0.070
response to extracellular stimulus GO:0009991 380 0.070
divalent inorganic cation homeostasis GO:0072507 165 0.069
vesicle mediated transport GO:0016192 181 0.068
cellular metal ion homeostasis GO:0006875 172 0.068
postsynaptic density protein 95 clustering GO:0097119 2 0.067
positive regulation of cell motility GO:2000147 97 0.066
regulation of secretion GO:0051046 224 0.066
positive regulation of cellular component biogenesis GO:0044089 55 0.066
action potential GO:0001508 54 0.065
positive regulation of response to stimulus GO:0048584 285 0.065
transmembrane transport GO:0055085 412 0.064
positive regulation of immune system process GO:0002684 90 0.062
cellular component biogenesis GO:0044085 368 0.061
single organism reproductive process GO:0044702 297 0.059
organelle localization GO:0051640 55 0.059
protein oligomerization GO:0051259 191 0.057
establishment of synaptic vesicle localization GO:0097480 23 0.057
cation homeostasis GO:0055080 195 0.056
cation transport GO:0006812 382 0.056
immune system process GO:0002376 204 0.056
positive regulation of secretion by cell GO:1903532 128 0.056
regulation of locomotion GO:0040012 148 0.054
regulation of multicellular organismal development GO:2000026 376 0.051
establishment of vesicle localization GO:0051650 31 0.049
protein homooligomerization GO:0051260 91 0.046
cell motility GO:0048870 202 0.046
regulation of vesicle mediated transport GO:0060627 81 0.045
synaptic transmission glycinergic GO:0060012 2 0.044
response to inorganic substance GO:0010035 377 0.042
positive regulation of cell development GO:0010720 176 0.042
positive regulation of secretion GO:0051047 140 0.040
regulation of neurotransmitter secretion GO:0046928 19 0.040
positive regulation of synaptic vesicle transport GO:1902805 3 0.039
positive regulation of signaling GO:0023056 270 0.039
positive regulation of inhibitory postsynaptic membrane potential GO:0097151 3 0.039
regulation of system process GO:0044057 208 0.039
regulation of nervous system development GO:0051960 264 0.038
positive regulation of synaptic vesicle exocytosis GO:2000302 3 0.038
synaptic transmission glutamatergic GO:0035249 33 0.037
response to metal ion GO:0010038 253 0.037
regulation of neurogenesis GO:0050767 247 0.037
synaptic vesicle recycling GO:0036465 5 0.037
regulation of cellular component organization GO:0051128 368 0.037
neuron projection development GO:0031175 273 0.037
multicellular organism reproduction GO:0032504 233 0.036
positive regulation of nervous system development GO:0051962 178 0.036
positive regulation of cellular component movement GO:0051272 102 0.036
cellular component morphogenesis GO:0032989 155 0.036
neuronal action potential GO:0019228 35 0.035
transmission of nerve impulse GO:0019226 42 0.035
multi organism reproductive process GO:0044703 262 0.034
protein complex assembly GO:0006461 263 0.034
organelle organization GO:0006996 266 0.034
cell morphogenesis GO:0000902 142 0.034
synaptic growth at neuromuscular junction GO:0051124 1 0.032
neurotransmitter transport GO:0006836 42 0.032
multicellular organismal reproductive process GO:0048609 233 0.032
neuron neuron synaptic transmission GO:0007270 60 0.032
positive regulation of signal transduction GO:0009967 175 0.032
axon ensheathment GO:0008366 40 0.032
regulation of homeostatic process GO:0032844 101 0.032
response to monosaccharide GO:0034284 159 0.031
amide transport GO:0042886 105 0.031
reproductive process GO:0022414 372 0.031
synaptic vesicle priming GO:0016082 4 0.031
cation transmembrane transport GO:0098655 263 0.031
gamete generation GO:0007276 124 0.031
regulation of neuron projection development GO:0010975 161 0.030
response to oxygen levels GO:0070482 265 0.030
peristalsis GO:0030432 2 0.030
regulation of intracellular signal transduction GO:1902531 218 0.030
regulation of hormone secretion GO:0046883 106 0.029
regulation of peptide transport GO:0090087 87 0.029
hormone transport GO:0009914 121 0.029
membrane organization GO:0061024 94 0.029
cell migration GO:0016477 197 0.029
gliogenesis GO:0042063 93 0.029
negative regulation of secretion GO:0051048 82 0.029
growth GO:0040007 165 0.029
detection of calcium ion GO:0005513 1 0.029
neuromuscular synaptic transmission GO:0007274 2 0.029
positive regulation of cell migration GO:0030335 96 0.029
regulation of neurotransmitter levels GO:0001505 42 0.029
leukocyte differentiation GO:0002521 30 0.028
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 3 0.028
response to growth factor GO:0070848 189 0.028
regulation of cell motility GO:2000145 131 0.028
regulation of cell projection organization GO:0031344 175 0.028
epithelium development GO:0060429 96 0.027
regulation of synaptic plasticity GO:0048167 70 0.027
positive regulation of immune response GO:0050778 42 0.027
nitrogen compound transport GO:0071705 229 0.027
metal ion transport GO:0030001 289 0.027
negative regulation of cell proliferation GO:0008285 119 0.027
cellular amine metabolic process GO:0044106 38 0.026
monovalent inorganic cation transport GO:0015672 172 0.026
localization of cell GO:0051674 202 0.026
adult locomotory behavior GO:0008344 4 0.026
regulation of immune response GO:0050776 55 0.026
g protein coupled receptor signaling pathway GO:0007186 242 0.025
cgmp catabolic process GO:0046069 6 0.025
gastrulation GO:0007369 2 0.025
macromolecule localization GO:0033036 252 0.025
defecation GO:0030421 1 0.025
cellular ketone metabolic process GO:0042180 51 0.025
response to external biotic stimulus GO:0043207 221 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
multicellular organismal signaling GO:0035637 44 0.025
regulation of cell migration GO:0030334 128 0.025
endomembrane system organization GO:0010256 48 0.025
regulation of catalytic activity GO:0050790 304 0.025
response to nutrient GO:0007584 248 0.024
tissue development GO:0009888 252 0.024
developmental process involved in reproduction GO:0003006 159 0.024
positive regulation of cell communication GO:0010647 271 0.024
endocytosis GO:0006897 84 0.023
ion transmembrane transport GO:0034220 365 0.023
cell adhesion GO:0007155 110 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
regulation of lipid metabolic process GO:0019216 68 0.022
sensory perception GO:0007600 101 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
regulation of peptide hormone secretion GO:0090276 80 0.022
axis specification GO:0009798 4 0.022
lymphoid progenitor cell differentiation GO:0002320 2 0.022
presynaptic membrane assembly GO:0097105 3 0.022
sexual reproduction GO:0019953 148 0.022
actin filament bundle assembly GO:0051017 19 0.021
regeneration GO:0031099 163 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
regulation of hormone levels GO:0010817 187 0.021
multicellular organism growth GO:0035264 1 0.020
retina morphogenesis in camera type eye GO:0060042 1 0.020
circulatory system process GO:0003013 183 0.020
single organism cellular localization GO:1902580 102 0.020
establishment of protein localization GO:0045184 141 0.020
locomotory exploration behavior GO:0035641 1 0.019
regulation of molecular function GO:0065009 398 0.019
regulation of signal transduction GO:0009966 318 0.019
ensheathment of neurons GO:0007272 40 0.019
positive regulation of synaptic transmission GO:0050806 62 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
cytoskeleton organization GO:0007010 111 0.019
cellular response to stress GO:0033554 269 0.019
sequestering of metal ion GO:0051238 9 0.018
regulation of neuron differentiation GO:0045664 208 0.018
reproduction GO:0000003 245 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
protein phosphorylation GO:0006468 345 0.018
receptor mediated endocytosis GO:0006898 42 0.018
dendrite development GO:0016358 72 0.018
sequestering of calcium ion GO:0051208 8 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
regulation of anatomical structure size GO:0090066 135 0.018
exploration behavior GO:0035640 1 0.017
regulation of synaptic transmission glutamatergic GO:0051966 26 0.017
cellular macromolecule localization GO:0070727 122 0.017
lipid modification GO:0030258 52 0.017
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.017
intracellular protein transport GO:0006886 79 0.017
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.017
positive regulation of neurotransmitter secretion GO:0001956 9 0.017
second messenger mediated signaling GO:0019932 51 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
locomotory behavior GO:0007626 15 0.017
asymmetric protein localization GO:0008105 2 0.017
organ regeneration GO:0031100 101 0.017
sodium ion transmembrane transport GO:0035725 67 0.017
regulation of smooth muscle cell proliferation GO:0048660 75 0.017
male gamete generation GO:0048232 99 0.016
oxoacid metabolic process GO:0043436 290 0.016
tongue morphogenesis GO:0043587 3 0.016
amine metabolic process GO:0009308 38 0.016
response to histamine GO:0034776 3 0.016
small molecule biosynthetic process GO:0044283 124 0.016
aging GO:0007568 241 0.016
cell fate commitment involved in pattern specification GO:0060581 2 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
single organism intracellular transport GO:1902582 166 0.016
organophosphate metabolic process GO:0019637 370 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
regulation of cellular component movement GO:0051270 150 0.015
positive regulation of synaptic vesicle recycling GO:1903423 1 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
embryonic axis specification GO:0000578 1 0.015
neuromuscular process GO:0050905 2 0.015
central nervous system development GO:0007417 311 0.015
response to reactive oxygen species GO:0000302 120 0.015
positive regulation of focal adhesion assembly GO:0051894 2 0.015
single organism membrane organization GO:0044802 74 0.015
regulation of synaptic vesicle endocytosis GO:1900242 1 0.015
regulation of tube size GO:0035150 89 0.015
endoplasmic reticulum organization GO:0007029 1 0.015
intracellular transport GO:0046907 185 0.015
protein tetramerization GO:0051262 38 0.015
regulation of notch signaling pathway GO:0008593 3 0.015
regulation of excretion GO:0044062 21 0.015
glial cell differentiation GO:0010001 65 0.015
cellular lipid metabolic process GO:0044255 208 0.015
phasic smooth muscle contraction GO:0014821 3 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
cellular response to alcohol GO:0097306 87 0.014
tube formation GO:0035148 3 0.014
immune system development GO:0002520 41 0.014
protein transport GO:0015031 132 0.014
negative regulation of signaling GO:0023057 157 0.014
anion transport GO:0006820 178 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
neurotransmitter gated ion channel clustering GO:0072578 3 0.014
regulation of dendrite development GO:0050773 59 0.014
regulated secretory pathway GO:0045055 17 0.014
regulation of cell proliferation GO:0042127 359 0.014
synaptic vesicle docking involved in exocytosis GO:0016081 2 0.013
regulation of neurotransmitter transport GO:0051588 21 0.013
phosphatidylinositol dephosphorylation GO:0046856 4 0.013
spermatogenesis GO:0007283 99 0.013
peptide transport GO:0015833 97 0.013
actin filament bundle organization GO:0061572 19 0.013
rhythmic process GO:0048511 156 0.013
response to decreased oxygen levels GO:0036293 237 0.013
calcium mediated signaling GO:0019722 23 0.013
cell growth GO:0016049 104 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
regulation of peptide secretion GO:0002791 82 0.013
developmental growth GO:0048589 100 0.013
regulation of synaptic vesicle transport GO:1902803 6 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
blood circulation GO:0008015 183 0.013
cell migration involved in metanephros development GO:0035788 2 0.013
peptide secretion GO:0002790 86 0.012
hair cell differentiation GO:0035315 2 0.012
ovulation cycle GO:0042698 67 0.012
response to mechanical stimulus GO:0009612 134 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
sodium ion transport GO:0006814 82 0.012
positive regulation of dendritic spine development GO:0060999 9 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
actin filament based process GO:0030029 86 0.012
response to vitamin GO:0033273 131 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
regulation of ion homeostasis GO:2000021 63 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
cellular protein localization GO:0034613 122 0.012
regulation of inflammatory response GO:0050727 48 0.012
neuron differentiation GO:0030182 368 0.012
b cell differentiation GO:0030183 2 0.012
establishment of tissue polarity GO:0007164 2 0.012
calcium ion dependent exocytosis GO:0017156 16 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
regulation of organelle organization GO:0033043 80 0.012
response to hypoxia GO:0001666 231 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
negative regulation of osteoblast differentiation GO:0045668 2 0.012
auditory receptor cell differentiation GO:0042491 2 0.012
glutamate receptor signaling pathway GO:0007215 43 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
cellular component movement GO:0006928 248 0.011
insulin secretion GO:0030073 69 0.011
cellular response to corticosteroid stimulus GO:0071384 69 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
regulation of regulated secretory pathway GO:1903305 7 0.011
response to vitamin a GO:0033189 36 0.011
lipid localization GO:0010876 62 0.011
cellular response to drug GO:0035690 30 0.011
negative regulation of cell development GO:0010721 82 0.011
mast cell degranulation GO:0043303 10 0.011
negative regulation of vesicle fusion GO:0031339 2 0.011
tube morphogenesis GO:0035239 23 0.011
reproductive structure development GO:0048608 128 0.011
regulation of cellular amino acid metabolic process GO:0006521 2 0.011
response to nutrient levels GO:0031667 370 0.011
vesicle organization GO:0016050 29 0.011
actin filament organization GO:0007015 42 0.011
anterior posterior pattern specification GO:0009952 1 0.011
cytoplasmic transport GO:0016482 115 0.011
ureteric bud development GO:0001657 14 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
embryonic pattern specification GO:0009880 1 0.011
negative regulation of metabolic process GO:0009892 331 0.011
rna localization GO:0006403 4 0.011
glycerolipid metabolic process GO:0046486 67 0.011
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 6 0.011
positive regulation of response to wounding GO:1903036 34 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
mesoderm development GO:0007498 2 0.011
gonad development GO:0008406 104 0.011
endoplasmic reticulum to cytosol transport GO:1903513 4 0.011
maintenance of location GO:0051235 17 0.010
ovulation cycle process GO:0022602 50 0.010
brain development GO:0007420 247 0.010
response to other organism GO:0051707 220 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
detection of chemical stimulus GO:0009593 10 0.010
regulation of phosphorylation GO:0042325 248 0.010
myeloid cell activation involved in immune response GO:0002275 13 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
carboxylic acid transport GO:0046942 115 0.010
regulation of ion transport GO:0043269 245 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
positive regulation of defense response GO:0031349 37 0.010
formation of primary germ layer GO:0001704 1 0.010

Magi1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.042
central nervous system disease DOID:331 0 0.017
musculoskeletal system disease DOID:17 0 0.015
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
disease of metabolism DOID:0014667 0 0.013
neuropathy DOID:870 0 0.011
cardiovascular system disease DOID:1287 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010