Rattus norvegicus

127 known processes

Map2k7

mitogen activated protein kinase kinase 7

(Aliases: 2,JNKK)

Map2k7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 379 0.195
Fly
rna biosynthetic process GO:0032774 380 0.181
Fly
intracellular signal transduction GO:0035556 314 0.177
regulation of nucleic acid templated transcription GO:1903506 380 0.172
Fly
regulation of transcription dna templated GO:0006355 374 0.171
Fly
transcription dna templated GO:0006351 377 0.150
Fly
regulation of signal transduction GO:0009966 318 0.115
chromatin modification GO:0016568 33 0.104
rna metabolic process GO:0016070 406 0.104
Fly
cellular response to oxygen containing compound GO:1901701 386 0.099
regulation of rna metabolic process GO:0051252 391 0.099
Fly
organelle organization GO:0006996 266 0.092
Worm Fly
single organism organelle organization GO:1902589 180 0.091
Fly
chromatin organization GO:0006325 34 0.087
regulation of cell differentiation GO:0045595 320 0.076
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.075
Rat Fly
neuron development GO:0048666 286 0.074
Fly
neuron projection development GO:0031175 273 0.070
Fly
anatomical structure morphogenesis GO:0009653 298 0.069
Zebrafish Fly
regulation of intracellular signal transduction GO:1902531 218 0.069
positive regulation of nucleic acid templated transcription GO:1903508 197 0.069
Fly
cellular response to endogenous stimulus GO:0071495 377 0.065
macromolecular complex subunit organization GO:0043933 339 0.064
Fly
positive regulation of developmental process GO:0051094 283 0.062
regulation of rna biosynthetic process GO:2001141 381 0.059
Fly
chromosome organization GO:0051276 36 0.057
amine metabolic process GO:0009308 38 0.057
positive regulation of biosynthetic process GO:0009891 319 0.055
Rat Fly
cellular component assembly GO:0022607 360 0.054
Fly
apoptotic process GO:0006915 381 0.052
cellular amine metabolic process GO:0044106 38 0.050
protein complex subunit organization GO:0071822 302 0.048
Fly
protein phosphorylation GO:0006468 345 0.048
programmed cell death GO:0012501 392 0.048
organic substance catabolic process GO:1901575 316 0.045
cellular response to lipid GO:0071396 201 0.045
Rat
neurological system process GO:0050877 219 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.043
histone modification GO:0016570 30 0.041
response to extracellular stimulus GO:0009991 380 0.041
Worm
neuron projection morphogenesis GO:0048812 122 0.041
Fly
regulation of nervous system development GO:0051960 264 0.040
regulation of neuron differentiation GO:0045664 208 0.040
cellular amino acid metabolic process GO:0006520 107 0.039
positive regulation of cellular component organization GO:0051130 200 0.039
positive regulation of response to stimulus GO:0048584 285 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
Rat Fly
regulation of phosphate metabolic process GO:0019220 349 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
Rat Fly
positive regulation of transcription dna templated GO:0045893 197 0.037
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
neuron differentiation GO:0030182 368 0.036
Fly
positive regulation of rna biosynthetic process GO:1902680 197 0.036
Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
aromatic compound catabolic process GO:0019439 168 0.035
cellular response to hormone stimulus GO:0032870 247 0.034
regulation of multicellular organismal development GO:2000026 376 0.034
regulation of molecular function GO:0065009 398 0.033
positive regulation of rna metabolic process GO:0051254 203 0.032
Fly
histone h3 acetylation GO:0043966 2 0.031
nucleotide metabolic process GO:0009117 279 0.031
small gtpase mediated signal transduction GO:0007264 36 0.031
response to inorganic substance GO:0010035 377 0.031
Worm Fly
regulation of proteasomal protein catabolic process GO:0061136 4 0.031
negative regulation of multicellular organismal process GO:0051241 203 0.031
positive regulation of cell communication GO:0010647 271 0.030
regulation of cell proliferation GO:0042127 359 0.030
negative regulation of developmental process GO:0051093 125 0.030
brain development GO:0007420 247 0.030
positive regulation of neuron differentiation GO:0045666 126 0.029
cellular component morphogenesis GO:0032989 155 0.029
Fly
cognition GO:0050890 92 0.029
catabolic process GO:0009056 351 0.029
Fly
covalent chromatin modification GO:0016569 30 0.029
negative regulation of cell communication GO:0010648 158 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.028
peptidyl amino acid modification GO:0018193 126 0.028
developmental growth GO:0048589 100 0.028
Rat Fly
single organism catabolic process GO:0044712 283 0.027
ras protein signal transduction GO:0007265 29 0.027
cellular response to growth factor stimulus GO:0071363 162 0.027
cellular nitrogen compound catabolic process GO:0044270 163 0.027
cellular component biogenesis GO:0044085 368 0.027
Fly
macromolecular complex assembly GO:0065003 273 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.027
negative regulation of phosphate metabolic process GO:0045936 80 0.026
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.026
Fly
organophosphate metabolic process GO:0019637 370 0.026
positive regulation of gene expression GO:0010628 244 0.026
Fly
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
organonitrogen compound catabolic process GO:1901565 179 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
regulation of protein modification process GO:0031399 194 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
organic cyclic compound catabolic process GO:1901361 175 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
nucleobase containing compound catabolic process GO:0034655 152 0.025
negative regulation of nervous system development GO:0051961 79 0.024
positive regulation of cell projection organization GO:0031346 111 0.024
protein complex biogenesis GO:0070271 263 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
heterocycle catabolic process GO:0046700 167 0.024
negative regulation of cell differentiation GO:0045596 99 0.023
response to metal ion GO:0010038 253 0.023
Worm Fly
regulation of phosphorylation GO:0042325 248 0.023
regulation of cell development GO:0060284 263 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
response to nutrient levels GO:0031667 370 0.023
Worm
transcription from rna polymerase ii promoter GO:0006366 252 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
immune system process GO:0002376 204 0.022
Fly
nucleotide catabolic process GO:0009166 139 0.022
negative regulation of signaling GO:0023057 157 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
response to monosaccharide GO:0034284 159 0.022
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
negative regulation of neuron differentiation GO:0045665 62 0.022
circadian rhythm GO:0007623 88 0.022
regulation of neurogenesis GO:0050767 247 0.022
regulation of cellular catabolic process GO:0031329 101 0.021
Fly
single organism behavior GO:0044708 130 0.021
nucleoside phosphate catabolic process GO:1901292 140 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
positive regulation of intracellular signal transduction GO:1902533 138 0.021
cell cell signaling GO:0007267 335 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
positive regulation of catabolic process GO:0009896 78 0.020
Fly
regulation of programmed cell death GO:0043067 341 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
carbohydrate derivative catabolic process GO:1901136 147 0.020
regulation of neuron projection development GO:0010975 161 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
response to tumor necrosis factor GO:0034612 56 0.020
Human
regulation of cellular component biogenesis GO:0044087 86 0.020
peptide biosynthetic process GO:0043043 3 0.020
regulation of apoptotic process GO:0042981 335 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
Rat Fly
central nervous system development GO:0007417 311 0.020
purine containing compound metabolic process GO:0072521 253 0.020
regulation of cellular component organization GO:0051128 368 0.019
neuron death GO:0070997 127 0.019
protein complex assembly GO:0006461 263 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.019
positive regulation of nervous system development GO:0051962 178 0.019
cell morphogenesis GO:0000902 142 0.019
Fly
cellular response to cytokine stimulus GO:0071345 127 0.018
regulation of hormone levels GO:0010817 187 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
regulation of catabolic process GO:0009894 113 0.018
Fly
cell part morphogenesis GO:0032990 123 0.018
Fly
glycosyl compound catabolic process GO:1901658 126 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
response to glucose GO:0009749 136 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
neurotrophin production GO:0032898 2 0.018
behavior GO:0007610 205 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
cellular response to abiotic stimulus GO:0071214 85 0.017
single organism intracellular transport GO:1902582 166 0.017
regulation of cellular localization GO:0060341 263 0.017
regulation of growth GO:0040008 105 0.017
Worm
purine nucleotide catabolic process GO:0006195 136 0.017
tissue development GO:0009888 252 0.016
Zebrafish Rat Fly
cellular response to organonitrogen compound GO:0071417 197 0.016
organ formation GO:0048645 3 0.016
response to vitamin GO:0033273 131 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
Rat Worm Fly
ribonucleotide catabolic process GO:0009261 136 0.016
cellular catabolic process GO:0044248 295 0.016
Fly
multicellular organism reproduction GO:0032504 233 0.016
Rat Worm Fly
protein oligomerization GO:0051259 191 0.016
response to lipopolysaccharide GO:0032496 191 0.016
Rat
regulation of protein metabolic process GO:0051246 289 0.016
organic acid metabolic process GO:0006082 292 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
negative regulation of organ growth GO:0046621 3 0.016
response to peptide GO:1901652 292 0.015
regulation of synaptic transmission GO:0050804 141 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
positive regulation of signaling GO:0023056 270 0.015
gland development GO:0048732 155 0.015
toxin transport GO:1901998 3 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
reproductive process GO:0022414 372 0.015
Rat Worm Fly
response to mechanical stimulus GO:0009612 134 0.015
regulation of hormone secretion GO:0046883 106 0.015
nucleoside metabolic process GO:0009116 179 0.014
embryonic pattern specification GO:0009880 1 0.014
cell fate determination GO:0001709 2 0.014
defense response GO:0006952 194 0.014
Worm Fly
negative regulation of neurogenesis GO:0050768 78 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
oxoacid metabolic process GO:0043436 290 0.014
muscle system process GO:0003012 115 0.014
Rat
negative regulation of cell development GO:0010721 82 0.014
regulation of protein kinase activity GO:0045859 105 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
chemosensory behavior GO:0007635 2 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
insulin like growth factor receptor signaling pathway GO:0048009 3 0.014
negative regulation of metabolic process GO:0009892 331 0.014
axis specification GO:0009798 4 0.014
protein transport GO:0015031 132 0.014
multi multicellular organism process GO:0044706 138 0.014
peptide hormone secretion GO:0030072 84 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
regulation of system process GO:0044057 208 0.013
regulation of peptide secretion GO:0002791 82 0.013
response to oxidative stress GO:0006979 186 0.013
cellular ketone metabolic process GO:0042180 51 0.013
regulation of membrane potential GO:0042391 110 0.013
growth GO:0040007 165 0.013
Rat Worm Fly
cellular response to stress GO:0033554 269 0.013
response to oxygen levels GO:0070482 265 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
lipid storage GO:0019915 1 0.013
memory GO:0007613 54 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
regulation of organelle organization GO:0033043 80 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
anion transport GO:0006820 178 0.012
Rat
gtp catabolic process GO:0006184 71 0.012
positive regulation of signal transduction GO:0009967 175 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
regulation of intracellular transport GO:0032386 65 0.012
cellular response to lipopolysaccharide GO:0071222 55 0.012
Rat
aging GO:0007568 241 0.012
Fly
olfactory behavior GO:0042048 2 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
regulation of rab protein signal transduction GO:0032483 3 0.012
multicellular organism growth GO:0035264 1 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
axon ensheathment GO:0008366 40 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
Zebrafish Fly
cell projection morphogenesis GO:0048858 123 0.012
Fly
response to hexose GO:0009746 144 0.012
negative regulation of cell death GO:0060548 229 0.012
positive regulation of synapse maturation GO:0090129 2 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
rab protein signal transduction GO:0032482 1 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
chemical homeostasis GO:0048878 292 0.011
Fly
amide transport GO:0042886 105 0.011
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.011
regulation of kinase activity GO:0043549 117 0.011
actin cytoskeleton organization GO:0030036 73 0.011
Fly
cell projection organization GO:0030030 302 0.011
Fly
cytoskeleton organization GO:0007010 111 0.011
Fly
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
muscle cell proliferation GO:0033002 84 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
response to carbohydrate GO:0009743 183 0.011
regulation of cell projection organization GO:0031344 175 0.011
response to growth factor GO:0070848 189 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
multi organism reproductive process GO:0044703 262 0.011
Worm Fly
negative regulation of signal transduction GO:0009968 83 0.011
cellular response to peptide GO:1901653 133 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
learning or memory GO:0007611 90 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
Fly
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of transferase activity GO:0051338 123 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
reproduction GO:0000003 245 0.011
Rat Worm Fly
cellular response to tumor necrosis factor GO:0071356 46 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
response to ethanol GO:0045471 162 0.011
negative regulation of protein modification process GO:0031400 52 0.011
response to estradiol GO:0032355 164 0.011
histone methylation GO:0016571 3 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.010
anterior posterior pattern specification GO:0009952 1 0.010
Zebrafish
response to estrogen GO:0043627 232 0.010
neuron apoptotic process GO:0051402 88 0.010
positive regulation of protein modification process GO:0031401 142 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
positive regulation of peptide secretion GO:0002793 52 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
proteolysis GO:0006508 175 0.010
response to cytokine GO:0034097 215 0.010
Human
spermatogenesis GO:0007283 99 0.010
negative regulation of gene expression GO:0010629 199 0.010
macromolecule catabolic process GO:0009057 58 0.010
glomerulus morphogenesis GO:0072102 1 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
single organism reproductive process GO:0044702 297 0.010
Rat Worm Fly

Map2k7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
sensory system disease DOID:0050155 0 0.013