Rattus norvegicus

7 known processes

Mbtps1

membrane-bound transcription factor peptidase, site 1

(Aliases: S1p,Ski-1)

Mbtps1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transcription dna templated GO:0045893 197 0.208
regulation of rna metabolic process GO:0051252 391 0.182
regulation of transcription dna templated GO:0006355 374 0.173
negative regulation of cellular metabolic process GO:0031324 281 0.126
negative regulation of metabolic process GO:0009892 331 0.111
transcription dna templated GO:0006351 377 0.107
axon development GO:0061564 96 0.104
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.098
regulation of rna biosynthetic process GO:2001141 381 0.098
transcription from rna polymerase ii promoter GO:0006366 252 0.095
regulation of protein modification process GO:0031399 194 0.094
rna metabolic process GO:0016070 406 0.083
regulation of signal transduction GO:0009966 318 0.082
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.082
regulation of nucleic acid templated transcription GO:1903506 380 0.082
single organism reproductive process GO:0044702 297 0.080
neuron projection development GO:0031175 273 0.079
nucleic acid templated transcription GO:0097659 379 0.077
regulation of cell proliferation GO:0042127 359 0.077
intracellular signal transduction GO:0035556 314 0.076
cellular response to stress GO:0033554 269 0.075
multi organism reproductive process GO:0044703 262 0.074
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.069
regulation of protein phosphorylation GO:0001932 183 0.068
cellular component assembly GO:0022607 360 0.067
positive regulation of gene expression GO:0010628 244 0.067
multicellular organismal reproductive process GO:0048609 233 0.067
protein complex biogenesis GO:0070271 263 0.067
cellular ion homeostasis GO:0006873 184 0.067
positive regulation of response to stimulus GO:0048584 285 0.067
reproductive process GO:0022414 372 0.065
organic acid metabolic process GO:0006082 292 0.063
cellular component biogenesis GO:0044085 368 0.062
oxoacid metabolic process GO:0043436 290 0.062
regulation of apoptotic process GO:0042981 335 0.060
positive regulation of signal transduction GO:0009967 175 0.059
cell morphogenesis involved in differentiation GO:0000904 119 0.056
positive regulation of signaling GO:0023056 270 0.056
multicellular organism reproduction GO:0032504 233 0.051
multi multicellular organism process GO:0044706 138 0.051
rna biosynthetic process GO:0032774 380 0.051
regulation of cellular localization GO:0060341 263 0.050
cellular chemical homeostasis GO:0055082 247 0.049
positive regulation of transport GO:0051050 245 0.049
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.049
carbohydrate derivative metabolic process GO:1901135 346 0.048
homeostatic process GO:0042592 331 0.048
regulation of phosphorus metabolic process GO:0051174 349 0.047
reproduction GO:0000003 245 0.046
positive regulation of rna biosynthetic process GO:1902680 197 0.046
negative regulation of multicellular organismal process GO:0051241 203 0.046
regulation of multicellular organismal development GO:2000026 376 0.046
positive regulation of cellular biosynthetic process GO:0031328 295 0.045
regulation of cell differentiation GO:0045595 320 0.043
regulation of cell cycle g1 s phase transition GO:1902806 7 0.043
positive regulation of cell differentiation GO:0045597 217 0.043
cytosolic calcium ion homeostasis GO:0051480 140 0.042
negative regulation of cell cycle g1 s phase transition GO:1902807 2 0.042
macromolecular complex assembly GO:0065003 273 0.041
positive regulation of multicellular organismal process GO:0051240 387 0.040
positive regulation of cell communication GO:0010647 271 0.040
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.039
peptidyl amino acid modification GO:0018193 126 0.039
positive regulation of nucleotide metabolic process GO:0045981 91 0.039
reproductive system development GO:0061458 128 0.039
axonogenesis GO:0007409 71 0.039
regulation of intracellular signal transduction GO:1902531 218 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
protein autophosphorylation GO:0046777 66 0.037
chemical homeostasis GO:0048878 292 0.037
regulation of cell development GO:0060284 263 0.037
protein phosphorylation GO:0006468 345 0.037
negative regulation of cellular biosynthetic process GO:0031327 161 0.037
positive regulation of molecular function GO:0044093 230 0.035
nucleotide metabolic process GO:0009117 279 0.035
regulation of molecular function GO:0065009 398 0.035
cellular response to hormone stimulus GO:0032870 247 0.035
regulation of phosphorylation GO:0042325 248 0.034
positive regulation of cell development GO:0010720 176 0.034
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.033
epithelial cell proliferation GO:0050673 54 0.033
immune system process GO:0002376 204 0.033
positive regulation of intracellular signal transduction GO:1902533 138 0.033
regulation of protein metabolic process GO:0051246 289 0.033
regulation of phosphate metabolic process GO:0019220 349 0.033
reproductive structure development GO:0048608 128 0.033
cellular response to endogenous stimulus GO:0071495 377 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
negative regulation of cell death GO:0060548 229 0.032
regulation of cellular component organization GO:0051128 368 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
regulation of hydrolase activity GO:0051336 143 0.032
negative regulation of rna metabolic process GO:0051253 123 0.031
cell type specific apoptotic process GO:0097285 134 0.031
ossification GO:0001503 70 0.031
divalent inorganic cation homeostasis GO:0072507 165 0.031
cell migration GO:0016477 197 0.031
single organism behavior GO:0044708 130 0.031
catabolic process GO:0009056 351 0.030
neuron differentiation GO:0030182 368 0.030
cellular amine metabolic process GO:0044106 38 0.030
neuron apoptotic process GO:0051402 88 0.030
response to extracellular stimulus GO:0009991 380 0.030
cellular amino acid metabolic process GO:0006520 107 0.029
negative regulation of programmed cell death GO:0043069 183 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
small gtpase mediated signal transduction GO:0007264 36 0.028
cellular response to lipid GO:0071396 201 0.028
protein complex subunit organization GO:0071822 302 0.028
cellular component movement GO:0006928 248 0.028
positive regulation of nucleic acid templated transcription GO:1903508 197 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.027
positive regulation of developmental process GO:0051094 283 0.027
rhythmic process GO:0048511 156 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
anatomical structure formation involved in morphogenesis GO:0048646 83 0.027
response to decreased oxygen levels GO:0036293 237 0.026
cation homeostasis GO:0055080 195 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
regulation of neuron differentiation GO:0045664 208 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
blood vessel morphogenesis GO:0048514 58 0.026
response to hydrogen peroxide GO:0042542 89 0.026
secretion GO:0046903 307 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
cellular homeostasis GO:0019725 252 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
central nervous system development GO:0007417 311 0.025
apoptotic process GO:0006915 381 0.025
growth GO:0040007 165 0.025
cellular response to growth factor stimulus GO:0071363 162 0.025
regulation of neurogenesis GO:0050767 247 0.024
appendage morphogenesis GO:0035107 4 0.024
regulation of catalytic activity GO:0050790 304 0.024
cellular ketone metabolic process GO:0042180 51 0.024
regulation of programmed cell death GO:0043067 341 0.024
cell projection organization GO:0030030 302 0.024
cellular metal ion homeostasis GO:0006875 172 0.023
positive regulation of cellular protein metabolic process GO:0032270 167 0.023
dna integrity checkpoint GO:0031570 2 0.023
limb morphogenesis GO:0035108 4 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
negative regulation of developmental process GO:0051093 125 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
axon choice point recognition GO:0016198 2 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
regulation of nucleotide metabolic process GO:0006140 117 0.022
vasculature development GO:0001944 70 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of cell projection organization GO:0031344 175 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
neuron development GO:0048666 286 0.022
cell growth GO:0016049 104 0.022
anterior posterior pattern specification GO:0009952 1 0.021
protein oligomerization GO:0051259 191 0.021
regulation of nervous system development GO:0051960 264 0.021
amine metabolic process GO:0009308 38 0.021
protein complex assembly GO:0006461 263 0.021
carboxylic acid metabolic process GO:0019752 289 0.021
metal ion transport GO:0030001 289 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
positive regulation of protein phosphorylation GO:0001934 135 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
positive regulation of nervous system development GO:0051962 178 0.020
response to glucose GO:0009749 136 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
regulation of growth GO:0040008 105 0.020
cellular cation homeostasis GO:0030003 180 0.020
sexual reproduction GO:0019953 148 0.020
regulation of protein transport GO:0051223 68 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
cell cell signaling GO:0007267 335 0.020
regulation of catabolic process GO:0009894 113 0.020
response to nutrient levels GO:0031667 370 0.020
cellular component morphogenesis GO:0032989 155 0.020
axis specification GO:0009798 4 0.020
positive regulation of cell death GO:0010942 184 0.020
negative regulation of cell cycle phase transition GO:1901988 4 0.019
regulation of immune response GO:0050776 55 0.019
regulation of neuron death GO:1901214 115 0.019
guanosine containing compound metabolic process GO:1901068 74 0.019
neuron projection morphogenesis GO:0048812 122 0.019
positive regulation of ion transport GO:0043270 94 0.019
response to peptide hormone GO:0043434 278 0.019
cellular response to external stimulus GO:0071496 118 0.019
glandular epithelial cell differentiation GO:0002067 4 0.019
negative regulation of gene expression GO:0010629 199 0.019
leukocyte activation GO:0045321 76 0.019
ion homeostasis GO:0050801 212 0.019
signal transduction by phosphorylation GO:0023014 144 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
negative regulation of viral process GO:0048525 4 0.018
response to cytokine GO:0034097 215 0.018
proteolysis GO:0006508 175 0.018
vasculogenesis GO:0001570 3 0.018
mesoderm development GO:0007498 2 0.018
hair cycle process GO:0022405 2 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
developmental process involved in reproduction GO:0003006 159 0.018
purine containing compound metabolic process GO:0072521 253 0.018
regulation of cell growth GO:0001558 85 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
regulation of cell cycle GO:0051726 73 0.018
development of primary sexual characteristics GO:0045137 107 0.018
cell morphogenesis GO:0000902 142 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
neuron death GO:0070997 127 0.018
embryo implantation GO:0007566 15 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
regulation of gtpase activity GO:0043087 57 0.017
response to oxygen levels GO:0070482 265 0.017
response to hexose GO:0009746 144 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.017
cellular response to extracellular stimulus GO:0031668 73 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
nucleotide catabolic process GO:0009166 139 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.017
defense response GO:0006952 194 0.017
regulation of mrna splicing via spliceosome GO:0048024 3 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
multicellular organism growth GO:0035264 1 0.016
protein processing GO:0016485 68 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
cyclic nucleotide biosynthetic process GO:0009190 63 0.016
positive regulation of protein modification process GO:0031401 142 0.016
cell cycle g1 s phase transition GO:0044843 13 0.016
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.016
gamete generation GO:0007276 124 0.016
negative regulation of molecular function GO:0044092 133 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
guanosine containing compound catabolic process GO:1901069 71 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
regulation of g1 s transition of mitotic cell cycle GO:2000045 6 0.016
response to carbohydrate GO:0009743 183 0.016
sex differentiation GO:0007548 113 0.015
developmental growth GO:0048589 100 0.015
brain development GO:0007420 247 0.015
wound healing GO:0042060 122 0.015
single organism catabolic process GO:0044712 283 0.015
response to acid chemical GO:0001101 222 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
programmed cell death GO:0012501 392 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
embryonic pattern specification GO:0009880 1 0.015
organelle organization GO:0006996 266 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
cell projection morphogenesis GO:0048858 123 0.015
regulation of protein kinase activity GO:0045859 105 0.015
tissue development GO:0009888 252 0.015
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
protein heterooligomerization GO:0051291 89 0.015
ras protein signal transduction GO:0007265 29 0.015
positive regulation of hydrolase activity GO:0051345 86 0.015
cardiovascular system development GO:0072358 134 0.014
cardiac chamber development GO:0003205 1 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
rho protein signal transduction GO:0007266 11 0.014
regulation of response to stress GO:0080134 126 0.014
molting cycle process GO:0022404 2 0.014
negative regulation of innate immune response GO:0045824 4 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
locomotion GO:0040011 237 0.014
protein maturation GO:0051604 68 0.014
response to growth factor GO:0070848 189 0.014
regulation of establishment of planar polarity GO:0090175 2 0.014
regulation of secretion GO:0051046 224 0.014
cyclic purine nucleotide metabolic process GO:0052652 62 0.014
regulation of epithelial cell proliferation GO:0050678 49 0.014
positive regulation of rac gtpase activity GO:0032855 5 0.014
motor neuron axon guidance GO:0008045 1 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
peptide biosynthetic process GO:0043043 3 0.013
regulation of neuron projection development GO:0010975 161 0.013
negative regulation of vasculature development GO:1901343 11 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
protein localization GO:0008104 191 0.013
response to peptide GO:1901652 292 0.013
cell activation GO:0001775 97 0.013
female pregnancy GO:0007565 122 0.013
regulation of fat cell differentiation GO:0045598 3 0.013
regulation of transferase activity GO:0051338 123 0.013
circadian rhythm GO:0007623 88 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
lymphocyte activation GO:0046649 43 0.013
circulatory system development GO:0072359 134 0.013
cell part morphogenesis GO:0032990 123 0.013
cytokine production GO:0001816 61 0.013
molting cycle GO:0042303 3 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
positive regulation of camp metabolic process GO:0030816 31 0.013
negative regulation of immune system process GO:0002683 39 0.013
g1 s transition of mitotic cell cycle GO:0000082 12 0.013
regulation of protein localization GO:0032880 81 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
muscle system process GO:0003012 115 0.012
ovulation cycle GO:0042698 67 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
negative regulation of cell communication GO:0010648 158 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.012
head development GO:0060322 247 0.012
ion transmembrane transport GO:0034220 365 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
cellular response to nutrient levels GO:0031669 60 0.012
response to ketone GO:1901654 182 0.012
behavior GO:0007610 205 0.012
organophosphate metabolic process GO:0019637 370 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
gtp metabolic process GO:0046039 72 0.012
mapk cascade GO:0000165 140 0.012
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.012
establishment of planar polarity GO:0001736 1 0.012
calcium ion homeostasis GO:0055074 162 0.012
pallium development GO:0021543 42 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
positive regulation of protein transport GO:0051222 41 0.012
regulation of immune system process GO:0002682 123 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
hippocampus development GO:0021766 30 0.012
negative regulation of growth GO:0045926 37 0.012
negative regulation of organ growth GO:0046621 3 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
hair follicle development GO:0001942 2 0.011
inflammatory response GO:0006954 150 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
regulation of anatomical structure size GO:0090066 135 0.011
protein secretion GO:0009306 34 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
response to estrogen GO:0043627 232 0.011
synapse assembly GO:0007416 29 0.011
spindle organization GO:0007051 2 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
actin filament based process GO:0030029 86 0.011
protein ubiquitination GO:0016567 28 0.011
protein transport GO:0015031 132 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
immune response GO:0006955 104 0.011
response to lipopolysaccharide GO:0032496 191 0.011
eye morphogenesis GO:0048592 4 0.011
positive regulation of humoral immune response GO:0002922 2 0.011
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
axon guidance GO:0007411 24 0.011
single organism organelle organization GO:1902589 180 0.011
dna damage checkpoint GO:0000077 2 0.011
secretion by cell GO:0032940 248 0.011
angiogenesis GO:0001525 53 0.011
establishment of tissue polarity GO:0007164 2 0.011
regulation of membrane potential GO:0042391 110 0.011
neurological system process GO:0050877 219 0.011
nitrogen compound transport GO:0071705 229 0.010
positive regulation of kinase activity GO:0033674 77 0.010
cellular response to peptide GO:1901653 133 0.010
cellular macromolecule localization GO:0070727 122 0.010
positive regulation of innate immune response GO:0045089 11 0.010
response to monosaccharide GO:0034284 159 0.010
nucleoside transport GO:0015858 8 0.010
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
embryonic skeletal system morphogenesis GO:0048704 3 0.010

Mbtps1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
connective tissue disease DOID:65 0 0.018
musculoskeletal system disease DOID:17 0 0.018
disease of anatomical entity DOID:7 0 0.018
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
cardiovascular system disease DOID:1287 0 0.011
vascular disease DOID:178 0 0.011
bone disease DOID:0080001 0 0.011