Rattus norvegicus

19 known processes

Mcl1

myeloid cell leukemia sequence 1

Mcl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of apoptotic process GO:0042981 335 0.100
regulation of smooth muscle cell proliferation GO:0048660 75 0.066
cellular response to lipid GO:0071396 201 0.054
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.052
regulation of transforming growth factor beta3 production GO:0032910 2 0.052
transforming growth factor beta3 production GO:0032907 2 0.049
cellular component biogenesis GO:0044085 368 0.047
muscle cell proliferation GO:0033002 84 0.047
rna biosynthetic process GO:0032774 380 0.047
regulation of cell differentiation GO:0045595 320 0.045
cellular response to hormone stimulus GO:0032870 247 0.043
carboxylic acid metabolic process GO:0019752 289 0.042
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.040
programmed cell death GO:0012501 392 0.039
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.039
positive regulation of developmental process GO:0051094 283 0.038
cellular ketone metabolic process GO:0042180 51 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
transcription from rna polymerase ii promoter GO:0006366 252 0.037
regulation of rna metabolic process GO:0051252 391 0.036
nucleic acid templated transcription GO:0097659 379 0.034
single organism carbohydrate metabolic process GO:0044723 118 0.034
carbohydrate metabolic process GO:0005975 130 0.034
monosaccharide metabolic process GO:0005996 61 0.033
positive regulation of neurogenesis GO:0050769 165 0.032
nucleotide metabolic process GO:0009117 279 0.032
peptidyl amino acid modification GO:0018193 126 0.032
smooth muscle cell proliferation GO:0048659 77 0.031
regulation of cell proliferation GO:0042127 359 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.030
nucleoside metabolic process GO:0009116 179 0.030
negative regulation of signaling GO:0023057 157 0.029
cellular amine metabolic process GO:0044106 38 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
purine nucleoside triphosphate metabolic process GO:0009144 141 0.029
positive regulation of cell projection organization GO:0031346 111 0.029
regulation of cell projection organization GO:0031344 175 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.028
transcription dna templated GO:0006351 377 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.028
positive regulation of nucleic acid templated transcription GO:1903508 197 0.028
regulation of molecular function GO:0065009 398 0.027
regulation of transcription dna templated GO:0006355 374 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
regulation of neuron projection development GO:0010975 161 0.027
homeostatic process GO:0042592 331 0.026
cellular response to stress GO:0033554 269 0.026
response to peptide GO:1901652 292 0.026
regulation of protein metabolic process GO:0051246 289 0.026
gastrulation GO:0007369 2 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
positive regulation of neuron projection development GO:0010976 99 0.025
protein phosphorylation GO:0006468 345 0.025
regulation of cell development GO:0060284 263 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
ribonucleoside triphosphate catabolic process GO:0009203 122 0.024
regulation of neurogenesis GO:0050767 247 0.024
amine metabolic process GO:0009308 38 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
ribose phosphate metabolic process GO:0019693 235 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
peptidyl tyrosine phosphorylation GO:0018108 72 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.021
cardiovascular system development GO:0072358 134 0.021
regulation of programmed cell death GO:0043067 341 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
apoptotic process GO:0006915 381 0.021
catabolic process GO:0009056 351 0.021
rna metabolic process GO:0016070 406 0.020
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.020
response to inorganic substance GO:0010035 377 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
central nervous system development GO:0007417 311 0.020
transmembrane transport GO:0055085 412 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
female pregnancy GO:0007565 122 0.019
regulation of proteasomal protein catabolic process GO:0061136 4 0.019
oxoacid metabolic process GO:0043436 290 0.019
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 3 0.019
negative regulation of phosphorus metabolic process GO:0010563 80 0.019
protein complex assembly GO:0006461 263 0.019
regulation of kinase activity GO:0043549 117 0.019
regulation of nervous system development GO:0051960 264 0.018
sex differentiation GO:0007548 113 0.018
peptidyl tyrosine modification GO:0018212 72 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
purine nucleotide catabolic process GO:0006195 136 0.018
response to extracellular stimulus GO:0009991 380 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
negative regulation of gene expression GO:0010629 199 0.018
brain development GO:0007420 247 0.018
single organism reproductive process GO:0044702 297 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
glucose metabolic process GO:0006006 52 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
regulation of multicellular organismal development GO:2000026 376 0.017
regulation of cellular component organization GO:0051128 368 0.017
immune system process GO:0002376 204 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
regulation of protein kinase activity GO:0045859 105 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
circadian rhythm GO:0007623 88 0.017
organophosphate metabolic process GO:0019637 370 0.017
organic acid metabolic process GO:0006082 292 0.017
lipid storage GO:0019915 1 0.016
response to reactive oxygen species GO:0000302 120 0.016
chemical homeostasis GO:0048878 292 0.016
dna methylation or demethylation GO:0044728 8 0.016
protein dephosphorylation GO:0006470 38 0.016
proteolysis GO:0006508 175 0.016
cellular catabolic process GO:0044248 295 0.016
positive regulation of cell death GO:0010942 184 0.016
organic substance catabolic process GO:1901575 316 0.016
cell motility GO:0048870 202 0.016
synaptic transmission GO:0007268 235 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
macromolecular complex assembly GO:0065003 273 0.015
metal ion transport GO:0030001 289 0.015
negative regulation of developmental process GO:0051093 125 0.015
regulation of transferase activity GO:0051338 123 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
membrane organization GO:0061024 94 0.015
peptide biosynthetic process GO:0043043 3 0.015
myeloid cell differentiation GO:0030099 22 0.015
calcium ion transport GO:0006816 131 0.015
intracellular signal transduction GO:0035556 314 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
regulation of catalytic activity GO:0050790 304 0.014
response to radiation GO:0009314 137 0.014
erythrocyte differentiation GO:0030218 1 0.014
reproductive system development GO:0061458 128 0.014
neuron death GO:0070997 127 0.014
multi multicellular organism process GO:0044706 138 0.014
positive regulation of molecular function GO:0044093 230 0.014
response to oxidative stress GO:0006979 186 0.014
regulation of catabolic process GO:0009894 113 0.014
negative regulation of metabolic process GO:0009892 331 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
regulation of signal transduction GO:0009966 318 0.014
cholesterol homeostasis GO:0042632 3 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
neuron differentiation GO:0030182 368 0.014
neuron projection development GO:0031175 273 0.014
negative regulation of cell differentiation GO:0045596 99 0.013
positive regulation of gene expression GO:0010628 244 0.013
response to hypoxia GO:0001666 231 0.013
regulation of cell motility GO:2000145 131 0.013
protein complex subunit organization GO:0071822 302 0.013
ras protein signal transduction GO:0007265 29 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
small gtpase mediated signal transduction GO:0007264 36 0.012
dna templated transcription initiation GO:0006352 4 0.012
response to cytokine GO:0034097 215 0.012
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.012
positive regulation of cell development GO:0010720 176 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of mapk cascade GO:0043408 116 0.012
response to camp GO:0051591 91 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
positive regulation of fat cell differentiation GO:0045600 2 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
regulation of cellular component movement GO:0051270 150 0.012
negative regulation of transport GO:0051051 136 0.012
macromolecule localization GO:0033036 252 0.012
response to estrogen GO:0043627 232 0.012
intracellular transport GO:0046907 185 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
protein complex biogenesis GO:0070271 263 0.012
negative regulation of cell communication GO:0010648 158 0.012
regulation of cytokine biosynthetic process GO:0042035 3 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
negative regulation of transcription dna templated GO:0045892 116 0.011
regulation of neuron differentiation GO:0045664 208 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
head development GO:0060322 247 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
regulation of synaptic transmission GO:0050804 141 0.011
response to toxic substance GO:0009636 133 0.011
organophosphate catabolic process GO:0046434 148 0.011
positive regulation of dna metabolic process GO:0051054 39 0.011
reproductive process GO:0022414 372 0.011
regulation of protein modification process GO:0031399 194 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
multi organism reproductive process GO:0044703 262 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.011
cell type specific apoptotic process GO:0097285 134 0.011
muscle cell migration GO:0014812 36 0.011
response to amino acid GO:0043200 75 0.010
erythrocyte homeostasis GO:0034101 2 0.010
response to external biotic stimulus GO:0043207 221 0.010
regulation of immunoglobulin production GO:0002637 4 0.010
negative regulation of signal transduction GO:0009968 83 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
localization of cell GO:0051674 202 0.010
protein heterooligomerization GO:0051291 89 0.010
protein catabolic process GO:0030163 30 0.010
smooth muscle cell migration GO:0014909 36 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
bmp signaling pathway GO:0030509 4 0.010
cytokine biosynthetic process GO:0042089 3 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
sterol homeostasis GO:0055092 3 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010

Mcl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017