Rattus norvegicus

0 known processes

Mcm5

minichromosome maintenance complex component 5

Mcm5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
chromosome segregation GO:0007059 2 0.121
anatomical structure morphogenesis GO:0009653 298 0.099
single organism reproductive process GO:0044702 297 0.096
positive regulation of developmental process GO:0051094 283 0.085
chromosome organization GO:0051276 36 0.082
regulation of molecular function GO:0065009 398 0.082
tetrahydrofolate metabolic process GO:0046653 9 0.081
regulation of protein modification process GO:0031399 194 0.078
dna metabolic process GO:0006259 96 0.075
multicellular organismal reproductive process GO:0048609 233 0.069
intracellular signal transduction GO:0035556 314 0.065
regulation of sister chromatid segregation GO:0033045 1 0.064
reproductive process GO:0022414 372 0.060
positive regulation of synapse maturation GO:0090129 2 0.059
regulation of exit from mitosis GO:0007096 1 0.059
cellular response to stress GO:0033554 269 0.056
aging GO:0007568 241 0.056
negative regulation of gene expression GO:0010629 199 0.055
regulation of ubiquitin protein transferase activity GO:0051438 1 0.054
double strand break repair GO:0006302 1 0.054
neuron differentiation GO:0030182 368 0.054
multi organism reproductive process GO:0044703 262 0.054
response to purine containing compound GO:0014074 126 0.054
cellular component biogenesis GO:0044085 368 0.051
regulation of neurogenesis GO:0050767 247 0.051
macromolecular complex subunit organization GO:0043933 339 0.050
regulation of cellular component organization GO:0051128 368 0.050
regulation of rna biosynthetic process GO:2001141 381 0.049
regulation of chromosome segregation GO:0051983 1 0.048
organelle organization GO:0006996 266 0.048
reproduction GO:0000003 245 0.046
response to metal ion GO:0010038 253 0.046
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.045
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
positive regulation of multicellular organismal process GO:0051240 387 0.044
organophosphate metabolic process GO:0019637 370 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.043
histone h3 k9 methylation GO:0051567 1 0.043
negative regulation of cell death GO:0060548 229 0.041
rhythmic process GO:0048511 156 0.040
negative regulation of developmental process GO:0051093 125 0.040
protein phosphorylation GO:0006468 345 0.040
regulation of cell proliferation GO:0042127 359 0.039
negative regulation of cellular metabolic process GO:0031324 281 0.039
regulation of cell differentiation GO:0045595 320 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.039
response to glucocorticoid GO:0051384 223 0.037
multicellular organism reproduction GO:0032504 233 0.036
mitotic sister chromatid separation GO:0051306 1 0.035
single organism organelle organization GO:1902589 180 0.035
cellular amino acid metabolic process GO:0006520 107 0.035
nucleic acid templated transcription GO:0097659 379 0.034
regeneration GO:0031099 163 0.034
regulation of transcription dna templated GO:0006355 374 0.033
somatic stem cell maintenance GO:0035019 2 0.033
organ regeneration GO:0031100 101 0.033
rna metabolic process GO:0016070 406 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
positive regulation of cell differentiation GO:0045597 217 0.031
cellular nitrogen compound catabolic process GO:0044270 163 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.030
protein transport GO:0015031 132 0.030
negative regulation of metabolic process GO:0009892 331 0.029
response to corticosteroid GO:0031960 235 0.029
spermatogenesis GO:0007283 99 0.029
single organism biosynthetic process GO:0044711 342 0.028
response to vitamin GO:0033273 131 0.027
single organism catabolic process GO:0044712 283 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
cellular macromolecule localization GO:0070727 122 0.027
chromosome condensation GO:0030261 3 0.027
regulation of protein phosphorylation GO:0001932 183 0.027
dna replication GO:0006260 37 0.027
regulation of cell cycle phase transition GO:1901987 12 0.027
response to transition metal nanoparticle GO:1990267 122 0.027
negative regulation of biosynthetic process GO:0009890 168 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
cellular component movement GO:0006928 248 0.026
regulation of rna metabolic process GO:0051252 391 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
neuronal stem cell maintenance GO:0097150 2 0.026
positive regulation of protein modification process GO:0031401 142 0.026
cellular response to endogenous stimulus GO:0071495 377 0.025
dna integrity checkpoint GO:0031570 2 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
chromatin assembly or disassembly GO:0006333 1 0.025
protein complex assembly GO:0006461 263 0.025
regulation of proteasomal protein catabolic process GO:0061136 4 0.025
response to ethanol GO:0045471 162 0.025
liver development GO:0001889 90 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
cellular component assembly GO:0022607 360 0.024
metaphase anaphase transition of cell cycle GO:0044784 1 0.024
histone h3 acetylation GO:0043966 2 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
sexual reproduction GO:0019953 148 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
regulation of cell development GO:0060284 263 0.024
response to nutrient levels GO:0031667 370 0.024
rna biosynthetic process GO:0032774 380 0.023
organic cyclic compound catabolic process GO:1901361 175 0.023
response to organophosphorus GO:0046683 102 0.023
regulation of synapse maturation GO:0090128 2 0.023
gamete generation GO:0007276 124 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
regulation of phosphate metabolic process GO:0019220 349 0.022
pteridine containing compound metabolic process GO:0042558 14 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
hepaticobiliary system development GO:0061008 90 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
transcription dna templated GO:0006351 377 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
anterior posterior pattern specification GO:0009952 1 0.021
purine containing compound metabolic process GO:0072521 253 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
regulation of dendrite development GO:0050773 59 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
cellular component morphogenesis GO:0032989 155 0.020
response to cytokine GO:0034097 215 0.020
regulation of phosphorylation GO:0042325 248 0.020
cerebellar purkinje cell layer morphogenesis GO:0021692 1 0.020
protein complex biogenesis GO:0070271 263 0.020
nucleosome organization GO:0034728 1 0.020
gland development GO:0048732 155 0.020
protein complex subunit organization GO:0071822 302 0.020
aromatic compound catabolic process GO:0019439 168 0.020
response to growth factor GO:0070848 189 0.020
regulation of neuron differentiation GO:0045664 208 0.019
nucleotide metabolic process GO:0009117 279 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
nucleoside metabolic process GO:0009116 179 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
circadian rhythm GO:0007623 88 0.019
neuron development GO:0048666 286 0.019
protein homooligomerization GO:0051260 91 0.019
protein targeting GO:0006605 61 0.019
regulation of mitotic sister chromatid separation GO:0010965 1 0.019
negative regulation of transcription dna templated GO:0045892 116 0.019
response to oxygen levels GO:0070482 265 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
tube development GO:0035295 89 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
response to extracellular stimulus GO:0009991 380 0.018
macromolecular complex assembly GO:0065003 273 0.018
response to peptide hormone GO:0043434 278 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
cardiovascular system development GO:0072358 134 0.018
cell cycle dna replication GO:0044786 1 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
cellular amine metabolic process GO:0044106 38 0.018
pyrimidine containing compound metabolic process GO:0072527 20 0.018
cellular response to oxygen containing compound GO:1901701 386 0.017
chromosome separation GO:0051304 1 0.017
response to wounding GO:0009611 254 0.017
regulation of neuron projection development GO:0010975 161 0.017
positive regulation of molecular function GO:0044093 230 0.017
coenzyme metabolic process GO:0006732 86 0.017
regulation of programmed cell death GO:0043067 341 0.017
programmed cell death GO:0012501 392 0.017
negative regulation of cell cycle phase transition GO:1901988 4 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
regulation of protein kinase activity GO:0045859 105 0.017
heterocycle catabolic process GO:0046700 167 0.017
female pregnancy GO:0007565 122 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
protein localization to chromosome centromeric region GO:0071459 1 0.016
cellular catabolic process GO:0044248 295 0.016
response to decreased oxygen levels GO:0036293 237 0.016
lipid metabolic process GO:0006629 283 0.016
cell cycle checkpoint GO:0000075 2 0.016
cell cycle g1 s phase transition GO:0044843 13 0.016
response to estradiol GO:0032355 164 0.016
mitotic dna damage checkpoint GO:0044773 1 0.016
regulation of mitotic sister chromatid segregation GO:0033047 1 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
protein modification by small protein conjugation or removal GO:0070647 35 0.016
negative regulation of cell division GO:0051782 1 0.016
negative regulation of cell communication GO:0010648 158 0.016
response to axon injury GO:0048678 59 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
male gamete generation GO:0048232 99 0.016
ras protein signal transduction GO:0007265 29 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
positive regulation of synaptic plasticity GO:0031915 3 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
oxoacid metabolic process GO:0043436 290 0.015
catabolic process GO:0009056 351 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
negative regulation of chromosome organization GO:2001251 1 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
cell projection organization GO:0030030 302 0.015
regulation of protein metabolic process GO:0051246 289 0.015
centrosome organization GO:0051297 1 0.015
negative regulation of nuclear division GO:0051784 1 0.015
regulation of cell projection organization GO:0031344 175 0.015
brain development GO:0007420 247 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
organic substance catabolic process GO:1901575 316 0.015
cell morphogenesis GO:0000902 142 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
organ morphogenesis GO:0009887 75 0.014
regulation of apoptotic process GO:0042981 335 0.014
positive regulation of transferase activity GO:0051347 81 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.014
response to ketone GO:1901654 182 0.014
positive regulation of cell development GO:0010720 176 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
cellular ketone metabolic process GO:0042180 51 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
metaphase plate congression GO:0051310 1 0.014
chromatin organization GO:0006325 34 0.014
homeostatic process GO:0042592 331 0.014
response to hypoxia GO:0001666 231 0.014
regulation of transferase activity GO:0051338 123 0.014
positive regulation of lipid catabolic process GO:0050996 4 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
regulation of cell cycle GO:0051726 73 0.014
regulation of dna metabolic process GO:0051052 60 0.013
regulation of cellular response to stress GO:0080135 49 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
response to amine GO:0014075 46 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
response to camp GO:0051591 91 0.013
protein localization GO:0008104 191 0.013
regulation of kinase activity GO:0043549 117 0.013
tissue development GO:0009888 252 0.013
sister chromatid segregation GO:0000819 1 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
regulation of catalytic activity GO:0050790 304 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
protein localization to organelle GO:0033365 57 0.013
cellular chemical homeostasis GO:0055082 247 0.013
ribonucleotide metabolic process GO:0009259 231 0.012
meiotic cell cycle process GO:1903046 3 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
response to toxic substance GO:0009636 133 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
response to indole 3 methanol GO:0071680 2 0.012
head development GO:0060322 247 0.012
ovulation cycle GO:0042698 67 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
ion homeostasis GO:0050801 212 0.012
regulation of cell cycle arrest GO:0071156 2 0.012
cellular protein localization GO:0034613 122 0.012
mitotic cell cycle phase transition GO:0044772 20 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
peptidyl amino acid modification GO:0018193 126 0.012
amine metabolic process GO:0009308 38 0.012
positive regulation of growth GO:0045927 55 0.012
response to inorganic substance GO:0010035 377 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
kidney development GO:0001822 67 0.011
organophosphate catabolic process GO:0046434 148 0.011
neuroblast differentiation GO:0014016 1 0.011
negative regulation of signaling GO:0023057 157 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.011
growth GO:0040007 165 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of nervous system development GO:0051960 264 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.011
heart development GO:0007507 72 0.011
histone h3 k9 modification GO:0061647 2 0.011
negative regulation of signal transduction GO:0009968 83 0.011
chemical homeostasis GO:0048878 292 0.011
cell cycle GO:0007049 101 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
regulation of growth GO:0040008 105 0.011
purine containing compound catabolic process GO:0072523 138 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
regulation of nuclear cell cycle dna replication GO:0033262 1 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
vesicle mediated transport GO:0016192 181 0.011
positive regulation of gene expression GO:0010628 244 0.011
single organism cellular localization GO:1902580 102 0.011
intracellular transport GO:0046907 185 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
regulation of cell cycle process GO:0010564 31 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
dna dependent dna replication GO:0006261 5 0.010
pyrimidine nucleotide biosynthetic process GO:0006221 9 0.010
muscle organ morphogenesis GO:0048644 1 0.010
synaptic transmission GO:0007268 235 0.010
axis specification GO:0009798 4 0.010
macromolecule localization GO:0033036 252 0.010
muscle tissue morphogenesis GO:0060415 1 0.010
ventricular cardiac muscle cell development GO:0055015 2 0.010

Mcm5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.023
cancer DOID:162 0 0.023
breast cancer DOID:1612 0 0.017
thoracic cancer DOID:5093 0 0.017
organ system cancer DOID:0050686 0 0.017