Rattus norvegicus

0 known processes

Mcm6

minichromosome maintenance complex component 6

(Aliases: Mcmd6)

Mcm6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 96 0.516
single organism reproductive process GO:0044702 297 0.229
regeneration GO:0031099 163 0.202
response to metal ion GO:0010038 253 0.201
nucleobase containing small molecule metabolic process GO:0055086 316 0.193
regulation of cell proliferation GO:0042127 359 0.185
cellular response to endogenous stimulus GO:0071495 377 0.182
reproductive system development GO:0061458 128 0.180
cellular response to acid chemical GO:0071229 75 0.171
alpha amino acid metabolic process GO:1901605 71 0.164
apoptotic process GO:0006915 381 0.158
dna dependent dna replication GO:0006261 5 0.134
triglyceride catabolic process GO:0019433 3 0.115
reproduction GO:0000003 245 0.111
chromatin modification GO:0016568 33 0.108
macromolecule localization GO:0033036 252 0.108
reproductive process GO:0022414 372 0.108
positive regulation of gene expression GO:0010628 244 0.107
negative regulation of chromosome organization GO:2001251 1 0.106
organelle organization GO:0006996 266 0.105
response to inorganic substance GO:0010035 377 0.102
positive regulation of lipid catabolic process GO:0050996 4 0.101
chromatin assembly or disassembly GO:0006333 1 0.100
regulation of cellular component organization GO:0051128 368 0.100
positive regulation of cell proliferation GO:0008284 249 0.099
response to purine containing compound GO:0014074 126 0.099
negative regulation of gene expression GO:0010629 199 0.098
cellular response to organonitrogen compound GO:0071417 197 0.098
response to ionizing radiation GO:0010212 59 0.097
regulation of programmed cell death GO:0043067 341 0.096
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.096
organ regeneration GO:0031100 101 0.096
chromatin organization GO:0006325 34 0.096
response to nutrient GO:0007584 248 0.095
response to estradiol GO:0032355 164 0.091
macromolecular complex subunit organization GO:0043933 339 0.090
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.090
single organism biosynthetic process GO:0044711 342 0.089
chromosome segregation GO:0007059 2 0.086
transcription from rna polymerase ii promoter GO:0006366 252 0.085
protein phosphorylation GO:0006468 345 0.083
aging GO:0007568 241 0.083
negative regulation of macromolecule metabolic process GO:0010605 260 0.083
negative regulation of cellular biosynthetic process GO:0031327 161 0.082
carboxylic acid metabolic process GO:0019752 289 0.081
oxoacid metabolic process GO:0043436 290 0.080
negative regulation of biosynthetic process GO:0009890 168 0.080
development of primary sexual characteristics GO:0045137 107 0.079
nucleoside phosphate metabolic process GO:0006753 283 0.079
regulation of molecular function GO:0065009 398 0.078
response to ethanol GO:0045471 162 0.076
rhythmic process GO:0048511 156 0.075
double strand break repair GO:0006302 1 0.074
purine nucleoside metabolic process GO:0042278 169 0.071
positive regulation of developmental process GO:0051094 283 0.071
cellular amino acid metabolic process GO:0006520 107 0.069
response to nutrient levels GO:0031667 370 0.068
base excision repair GO:0006284 6 0.067
dna conformation change GO:0071103 10 0.067
dna packaging GO:0006323 4 0.066
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.066
response to estrogen GO:0043627 232 0.065
reproductive structure development GO:0048608 128 0.064
response to alkaloid GO:0043279 132 0.064
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.064
organic cyclic compound catabolic process GO:1901361 175 0.063
head development GO:0060322 247 0.062
organophosphate metabolic process GO:0019637 370 0.061
positive regulation of rna metabolic process GO:0051254 203 0.060
negative regulation of apoptotic process GO:0043066 181 0.059
response to peptide hormone GO:0043434 278 0.057
regulation of gene expression epigenetic GO:0040029 10 0.056
cell motility GO:0048870 202 0.055
rna metabolic process GO:0016070 406 0.054
purine containing compound metabolic process GO:0072521 253 0.053
central nervous system development GO:0007417 311 0.051
response to amino acid GO:0043200 75 0.051
pyrimidine nucleobase metabolic process GO:0006206 8 0.051
positive regulation of biosynthetic process GO:0009891 319 0.051
positive regulation of apoptotic process GO:0043065 154 0.050
nucleobase containing compound catabolic process GO:0034655 152 0.050
immune system process GO:0002376 204 0.050
cell cycle checkpoint GO:0000075 2 0.049
cellular nitrogen compound catabolic process GO:0044270 163 0.049
organic acid metabolic process GO:0006082 292 0.049
hematopoietic progenitor cell differentiation GO:0002244 2 0.049
response to lipopolysaccharide GO:0032496 191 0.049
male gonad development GO:0008584 59 0.048
programmed cell death GO:0012501 392 0.048
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.047
response to toxic substance GO:0009636 133 0.047
regulation of rna biosynthetic process GO:2001141 381 0.047
regulation of nuclear cell cycle dna replication GO:0033262 1 0.047
multicellular organism reproduction GO:0032504 233 0.045
cellular response to oxygen containing compound GO:1901701 386 0.045
nucleic acid templated transcription GO:0097659 379 0.045
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.045
brain development GO:0007420 247 0.045
single organism catabolic process GO:0044712 283 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.044
positive regulation of cell migration GO:0030335 96 0.044
organophosphate catabolic process GO:0046434 148 0.044
nucleoside metabolic process GO:0009116 179 0.043
tissue development GO:0009888 252 0.043
cellular response to nitrogen compound GO:1901699 210 0.041
regulation of apoptotic process GO:0042981 335 0.041
rna biosynthetic process GO:0032774 380 0.040
chemical homeostasis GO:0048878 292 0.040
neuron differentiation GO:0030182 368 0.040
negative regulation of cell communication GO:0010648 158 0.040
response to peptide GO:1901652 292 0.040
cellular modified amino acid metabolic process GO:0006575 61 0.040
response to cadmium ion GO:0046686 35 0.039
eye development GO:0001654 50 0.039
homeostatic process GO:0042592 331 0.039
response to ketone GO:1901654 182 0.039
regulation of transcription dna templated GO:0006355 374 0.038
protein localization to chromosome centromeric region GO:0071459 1 0.038
sexual reproduction GO:0019953 148 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.037
apoptotic signaling pathway GO:0097190 27 0.037
ventricular cardiac muscle cell development GO:0055015 2 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.036
response to vitamin GO:0033273 131 0.036
negative regulation of rna metabolic process GO:0051253 123 0.035
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.035
response to lead ion GO:0010288 33 0.035
response to oxygen levels GO:0070482 265 0.035
axis specification GO:0009798 4 0.035
aromatic compound catabolic process GO:0019439 168 0.034
negative regulation of nucleic acid templated transcription GO:1903507 117 0.034
cerebellar cortex formation GO:0021697 2 0.034
positive regulation of transport GO:0051050 245 0.034
negative regulation of rna biosynthetic process GO:1902679 118 0.034
response to growth factor GO:0070848 189 0.033
glycosyl compound metabolic process GO:1901657 182 0.033
nucleotide metabolic process GO:0009117 279 0.033
cell cycle g1 s phase transition GO:0044843 13 0.033
sex differentiation GO:0007548 113 0.032
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
macromolecular complex assembly GO:0065003 273 0.032
purine containing compound catabolic process GO:0072523 138 0.032
nucleoside triphosphate metabolic process GO:0009141 144 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
regulation of homeostatic process GO:0032844 101 0.031
positive regulation of transcription dna templated GO:0045893 197 0.031
regulation of rna metabolic process GO:0051252 391 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
erythrocyte differentiation GO:0030218 1 0.030
cell cycle dna replication GO:0044786 1 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
transcription dna templated GO:0006351 377 0.030
gonad development GO:0008406 104 0.029
multicellular organismal reproductive process GO:0048609 233 0.029
heterocycle catabolic process GO:0046700 167 0.029
regulation of dna metabolic process GO:0051052 60 0.029
nucleosome organization GO:0034728 1 0.029
negative regulation of response to stimulus GO:0048585 155 0.029
regulation of apoptotic signaling pathway GO:2001233 13 0.029
cellular response to stress GO:0033554 269 0.028
negative regulation of programmed cell death GO:0043069 183 0.028
multi organism reproductive process GO:0044703 262 0.028
response to extracellular stimulus GO:0009991 380 0.027
negative regulation of transcription dna templated GO:0045892 116 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
ribonucleoside metabolic process GO:0009119 174 0.027
gamete generation GO:0007276 124 0.027
cell cycle GO:0007049 101 0.027
cell type specific apoptotic process GO:0097285 134 0.027
response to activity GO:0014823 73 0.026
spermatogenesis GO:0007283 99 0.026
positive regulation of molecular function GO:0044093 230 0.026
response to radiation GO:0009314 137 0.026
cellular response to lipid GO:0071396 201 0.026
developmental process involved in reproduction GO:0003006 159 0.026
purine nucleotide metabolic process GO:0006163 229 0.025
response to external biotic stimulus GO:0043207 221 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
regulation of organelle organization GO:0033043 80 0.025
organic substance catabolic process GO:1901575 316 0.025
positive regulation of triglyceride metabolic process GO:0090208 4 0.025
cellular response to growth factor stimulus GO:0071363 162 0.025
cerebellar purkinje cell differentiation GO:0021702 1 0.024
positive regulation of protein modification process GO:0031401 142 0.024
pyrimidine deoxyribonucleotide metabolic process GO:0009219 5 0.024
response to acid chemical GO:0001101 222 0.024
cellular amine metabolic process GO:0044106 38 0.024
regulation of g2 m transition of mitotic cell cycle GO:0010389 4 0.024
cellular component biogenesis GO:0044085 368 0.024
development of primary male sexual characteristics GO:0046546 59 0.023
response to decreased oxygen levels GO:0036293 237 0.023
negative regulation of metabolic process GO:0009892 331 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
negative regulation of signaling GO:0023057 157 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
atp metabolic process GO:0046034 72 0.023
pyrimidine containing compound metabolic process GO:0072527 20 0.022
circadian rhythm GO:0007623 88 0.022
mitotic dna damage checkpoint GO:0044773 1 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
protein complex biogenesis GO:0070271 263 0.022
positive regulation of catabolic process GO:0009896 78 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
male sex differentiation GO:0046661 64 0.022
chromatin remodeling GO:0006338 3 0.022
positive regulation of cytoskeleton organization GO:0051495 26 0.022
cellular response to insulin stimulus GO:0032869 81 0.022
localization of cell GO:0051674 202 0.022
cellular ketone metabolic process GO:0042180 51 0.022
chromosome organization GO:0051276 36 0.022
histone methylation GO:0016571 3 0.022
triglyceride metabolic process GO:0006641 21 0.021
positive regulation of dna metabolic process GO:0051054 39 0.021
cerebellar purkinje cell layer development GO:0021680 2 0.021
protein complex assembly GO:0006461 263 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
developmental growth GO:0048589 100 0.021
cellular response to abiotic stimulus GO:0071214 85 0.021
cardiac muscle cell development GO:0055013 16 0.021
negative regulation of protein metabolic process GO:0051248 114 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.020
nucleoside phosphate catabolic process GO:1901292 140 0.020
protein homooligomerization GO:0051260 91 0.020
dna replication GO:0006260 37 0.020
positive regulation of hydrolase activity GO:0051345 86 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
response to molecule of bacterial origin GO:0002237 194 0.019
response to corticosterone GO:0051412 40 0.019
response to hypoxia GO:0001666 231 0.019
amine metabolic process GO:0009308 38 0.019
response to camp GO:0051591 91 0.019
response to biotic stimulus GO:0009607 226 0.019
regulation of triglyceride catabolic process GO:0010896 1 0.019
ribose phosphate metabolic process GO:0019693 235 0.018
response to caffeine GO:0031000 18 0.018
catabolic process GO:0009056 351 0.018
cellular response to peptide GO:1901653 133 0.018
coenzyme metabolic process GO:0006732 86 0.018
camera type eye development GO:0043010 48 0.017
peptidyl amino acid modification GO:0018193 126 0.017
regulation of cell differentiation GO:0045595 320 0.017
cellular component morphogenesis GO:0032989 155 0.017
response to other organism GO:0051707 220 0.017
cytoplasmic transport GO:0016482 115 0.017
purine nucleoside monophosphate metabolic process GO:0009126 84 0.017
response to organophosphorus GO:0046683 102 0.017
male gamete generation GO:0048232 99 0.017
skeletal system development GO:0001501 41 0.017
ion homeostasis GO:0050801 212 0.016
nucleotide biosynthetic process GO:0009165 98 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
regulation of hydrolase activity GO:0051336 143 0.016
response to epidermal growth factor GO:0070849 18 0.016
g1 s transition of mitotic cell cycle GO:0000082 12 0.016
cellular cation homeostasis GO:0030003 180 0.016
protein localization GO:0008104 191 0.016
negative regulation of molecular function GO:0044092 133 0.016
leydig cell differentiation GO:0033327 8 0.016
anion transport GO:0006820 178 0.016
response to reactive oxygen species GO:0000302 120 0.015
chromosome condensation GO:0030261 3 0.015
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.015
response to light stimulus GO:0009416 52 0.015
dna integrity checkpoint GO:0031570 2 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
regulation of protein modification process GO:0031399 194 0.015
cell differentiation in hindbrain GO:0021533 2 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
mitotic cell cycle phase transition GO:0044772 20 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
intracellular protein transport GO:0006886 79 0.015
negative regulation of signal transduction GO:0009968 83 0.015
regulation of catalytic activity GO:0050790 304 0.015
negative regulation of cell cycle phase transition GO:1901988 4 0.015
cell projection organization GO:0030030 302 0.014
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.014
chemotaxis GO:0006935 66 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
muscle organ development GO:0007517 50 0.014
response to fatty acid GO:0070542 65 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
neuron projection morphogenesis GO:0048812 122 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
deoxyribonucleotide biosynthetic process GO:0009263 6 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
taxis GO:0042330 67 0.014
cell morphogenesis GO:0000902 142 0.014
protein oligomerization GO:0051259 191 0.014
tetrahydrofolate metabolic process GO:0046653 9 0.014
positive regulation of cell development GO:0010720 176 0.014
regulation of protein metabolic process GO:0051246 289 0.013
extrinsic apoptotic signaling pathway GO:0097191 10 0.013
response to testosterone GO:0033574 55 0.013
cardiac cell development GO:0055006 16 0.013
cellular component movement GO:0006928 248 0.013
response to amine GO:0014075 46 0.013
negative regulation of neuron death GO:1901215 69 0.013
response to mechanical stimulus GO:0009612 134 0.013
cellular chemical homeostasis GO:0055082 247 0.013
ovulation cycle process GO:0022602 50 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
cellular response to purine containing compound GO:0071415 2 0.013
positive regulation of nervous system development GO:0051962 178 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
regulation of cell migration GO:0030334 128 0.013
response to insulin GO:0032868 133 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
regulation of neurogenesis GO:0050767 247 0.013
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.013
pyrimidine nucleotide biosynthetic process GO:0006221 9 0.013
protein transport GO:0015031 132 0.013
single organism organelle organization GO:1902589 180 0.012
cell migration GO:0016477 197 0.012
cellular response to dna damage stimulus GO:0006974 19 0.012
epithelial cell proliferation GO:0050673 54 0.012
protein autophosphorylation GO:0046777 66 0.012
learning or memory GO:0007611 90 0.012
cellular response to external stimulus GO:0071496 118 0.012
nucleotide catabolic process GO:0009166 139 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
cofactor metabolic process GO:0051186 95 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
muscle cell proliferation GO:0033002 84 0.012
positive regulation of growth GO:0045927 55 0.012
anion transmembrane transport GO:0098656 77 0.012
intracellular transport GO:0046907 185 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
growth GO:0040007 165 0.012
muscle structure development GO:0061061 87 0.012
cellular catabolic process GO:0044248 295 0.012
histone h3 k9 modification GO:0061647 2 0.012
ovulation cycle GO:0042698 67 0.012
mitotic cell cycle checkpoint GO:0007093 1 0.012
response to bacterium GO:0009617 200 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
memory GO:0007613 54 0.011
cell chemotaxis GO:0060326 31 0.011
response to wounding GO:0009611 254 0.011
neuron projection development GO:0031175 273 0.011
dna damage checkpoint GO:0000077 2 0.011
deoxyribonucleoside monophosphate biosynthetic process GO:0009157 4 0.011
epithelium development GO:0060429 96 0.011
cellular response to metal ion GO:0071248 55 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
female sex differentiation GO:0046660 59 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
regulation of cellular localization GO:0060341 263 0.011
mrna metabolic process GO:0016071 20 0.011
spindle organization GO:0007051 2 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
cellular modified amino acid biosynthetic process GO:0042398 18 0.011
erythrocyte homeostasis GO:0034101 2 0.011
histone serine phosphorylation GO:0035404 1 0.011
nitrogen compound transport GO:0071705 229 0.011
regulation of growth GO:0040008 105 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
locomotion GO:0040011 237 0.011
regulation of phosphorus metabolic process GO:0051174 349 0.010
secretion GO:0046903 307 0.010
epithelial cell differentiation GO:0030855 71 0.010
histone modification GO:0016570 30 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
sensory organ development GO:0007423 74 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
regulation of cell development GO:0060284 263 0.010
anterior posterior pattern specification GO:0009952 1 0.010
response to carbohydrate GO:0009743 183 0.010
regulation of mrna splicing via spliceosome GO:0048024 3 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.010
response to cytokine GO:0034097 215 0.010
lipid metabolic process GO:0006629 283 0.010

Mcm6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.068
disease of cellular proliferation DOID:14566 0 0.068
organ system cancer DOID:0050686 0 0.032
gastrointestinal system cancer DOID:3119 0 0.027
intestinal cancer DOID:10155 0 0.027
large intestine cancer DOID:5672 0 0.021
breast cancer DOID:1612 0 0.018
thoracic cancer DOID:5093 0 0.018
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
neuropathy DOID:870 0 0.017
colon cancer DOID:219 0 0.013
colorectal cancer DOID:9256 0 0.013