Rattus norvegicus

15 known processes

Mcm7

minichromosome maintenance complex component 7

(Aliases: MGC93853)

Mcm7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna packaging GO:0006323 4 0.578
dna metabolic process GO:0006259 96 0.573
chromatin assembly or disassembly GO:0006333 1 0.535
chromatin organization GO:0006325 34 0.338
single organism reproductive process GO:0044702 297 0.287
rna metabolic process GO:0016070 406 0.270
nucleosome organization GO:0034728 1 0.244
chromosome organization GO:0051276 36 0.223
regulation of protein metabolic process GO:0051246 289 0.163
macromolecular complex subunit organization GO:0043933 339 0.160
regulation of cell proliferation GO:0042127 359 0.151
transcription from rna polymerase ii promoter GO:0006366 252 0.150
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.148
chromosome segregation GO:0007059 2 0.146
negative regulation of cellular metabolic process GO:0031324 281 0.138
regulation of cellular component organization GO:0051128 368 0.134
negative regulation of metabolic process GO:0009892 331 0.122
reproductive process GO:0022414 372 0.120
organic acid metabolic process GO:0006082 292 0.116
histone h3 k9 methylation GO:0051567 1 0.116
regulation of nucleic acid templated transcription GO:1903506 380 0.104
negative regulation of macromolecule metabolic process GO:0010605 260 0.102
organelle organization GO:0006996 266 0.101
multi organism reproductive process GO:0044703 262 0.097
regulation of rna metabolic process GO:0051252 391 0.095
regulation of chromosome organization GO:0033044 9 0.086
negative regulation of gene expression GO:0010629 199 0.085
regulation of transcription dna templated GO:0006355 374 0.084
histone modification GO:0016570 30 0.082
regulation of rna biosynthetic process GO:2001141 381 0.077
macromolecule localization GO:0033036 252 0.074
cellular component assembly GO:0022607 360 0.073
carboxylic acid metabolic process GO:0019752 289 0.073
neuron differentiation GO:0030182 368 0.071
cellular component biogenesis GO:0044085 368 0.071
regulation of proteasomal protein catabolic process GO:0061136 4 0.068
macromolecular complex assembly GO:0065003 273 0.065
regulation of phosphate metabolic process GO:0019220 349 0.065
regulation of cellular protein metabolic process GO:0032268 267 0.064
response to inorganic substance GO:0010035 377 0.063
nucleic acid templated transcription GO:0097659 379 0.061
protein phosphorylation GO:0006468 345 0.060
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.060
chromatin modification GO:0016568 33 0.059
oxoacid metabolic process GO:0043436 290 0.058
cell cycle dna replication GO:0044786 1 0.058
rna biosynthetic process GO:0032774 380 0.058
sensory organ development GO:0007423 74 0.058
transcription dna templated GO:0006351 377 0.057
cellular amino acid metabolic process GO:0006520 107 0.057
purine containing compound metabolic process GO:0072521 253 0.057
cellular response to oxygen containing compound GO:1901701 386 0.056
cellular response to endogenous stimulus GO:0071495 377 0.054
negative regulation of biosynthetic process GO:0009890 168 0.052
cellular response to stress GO:0033554 269 0.052
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.051
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.050
positive regulation of gene expression GO:0010628 244 0.049
regulation of molecular function GO:0065009 398 0.048
response to extracellular stimulus GO:0009991 380 0.047
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.047
positive regulation of transcription dna templated GO:0045893 197 0.044
regulation of protein modification process GO:0031399 194 0.044
cell cycle checkpoint GO:0000075 2 0.044
negative regulation of cellular biosynthetic process GO:0031327 161 0.044
aging GO:0007568 241 0.043
regulation of cellular localization GO:0060341 263 0.043
epithelium development GO:0060429 96 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.042
organic substance catabolic process GO:1901575 316 0.042
head development GO:0060322 247 0.042
positive regulation of protein modification process GO:0031401 142 0.041
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.040
regulation of cell development GO:0060284 263 0.040
regulation of phosphorus metabolic process GO:0051174 349 0.040
response to alkaloid GO:0043279 132 0.038
negative regulation of rna biosynthetic process GO:1902679 118 0.038
gamete generation GO:0007276 124 0.038
programmed cell death GO:0012501 392 0.037
cellular catabolic process GO:0044248 295 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
regulation of cell cycle GO:0051726 73 0.036
regulation of cell differentiation GO:0045595 320 0.036
positive regulation of rna biosynthetic process GO:1902680 197 0.036
positive regulation of cellular biosynthetic process GO:0031328 295 0.036
cellular response to nitrogen compound GO:1901699 210 0.036
response to metal ion GO:0010038 253 0.036
nucleoside triphosphate metabolic process GO:0009141 144 0.035
multicellular organismal reproductive process GO:0048609 233 0.035
protein maturation GO:0051604 68 0.035
protein complex assembly GO:0006461 263 0.034
protein complex biogenesis GO:0070271 263 0.034
positive regulation of protein metabolic process GO:0051247 178 0.034
cell cycle GO:0007049 101 0.034
positive regulation of transport GO:0051050 245 0.033
regulation of cellular amine metabolic process GO:0033238 8 0.033
tissue development GO:0009888 252 0.033
multicellular organism reproduction GO:0032504 233 0.033
neuron development GO:0048666 286 0.032
cellular protein localization GO:0034613 122 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
brain development GO:0007420 247 0.032
catabolic process GO:0009056 351 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
proteolysis GO:0006508 175 0.031
regulation of multicellular organismal development GO:2000026 376 0.031
positive regulation of programmed cell death GO:0043068 157 0.030
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
negative regulation of transcription dna templated GO:0045892 116 0.030
negative regulation of signaling GO:0023057 157 0.030
negative regulation of cell cycle phase transition GO:1901988 4 0.030
nucleocytoplasmic transport GO:0006913 48 0.030
peptidyl amino acid modification GO:0018193 126 0.029
response to nutrient levels GO:0031667 370 0.029
response to radiation GO:0009314 137 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
organic cyclic compound catabolic process GO:1901361 175 0.029
establishment of protein localization GO:0045184 141 0.029
cellular ketone metabolic process GO:0042180 51 0.028
apoptotic process GO:0006915 381 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
regulation of organelle organization GO:0033043 80 0.028
neuron projection development GO:0031175 273 0.027
regulation of programmed cell death GO:0043067 341 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
circulatory system development GO:0072359 134 0.027
cellular nitrogen compound catabolic process GO:0044270 163 0.027
meiotic cell cycle process GO:1903046 3 0.027
single organism biosynthetic process GO:0044711 342 0.026
negative regulation of chromosome organization GO:2001251 1 0.026
protein localization GO:0008104 191 0.026
response to toxic substance GO:0009636 133 0.026
single organism organelle organization GO:1902589 180 0.026
response to hypoxia GO:0001666 231 0.026
positive regulation of molecular function GO:0044093 230 0.025
histone h3 k9 modification GO:0061647 2 0.025
eye development GO:0001654 50 0.025
cell projection organization GO:0030030 302 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
cellular macromolecular complex assembly GO:0034622 58 0.025
ribose phosphate metabolic process GO:0019693 235 0.025
positive regulation of signaling GO:0023056 270 0.025
cellular amine metabolic process GO:0044106 38 0.024
reproductive structure development GO:0048608 128 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.024
response to decreased oxygen levels GO:0036293 237 0.024
spindle organization GO:0007051 2 0.024
cellular response to organonitrogen compound GO:0071417 197 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
dna conformation change GO:0071103 10 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
histone serine phosphorylation GO:0035404 1 0.023
negative regulation of cellular component organization GO:0051129 83 0.023
regulation of phosphorylation GO:0042325 248 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.022
positive regulation of developmental process GO:0051094 283 0.022
meiosis i GO:0007127 2 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
nucleobase containing compound catabolic process GO:0034655 152 0.022
cellular response to abiotic stimulus GO:0071214 85 0.022
regulation of cellular catabolic process GO:0031329 101 0.022
negative regulation of cell communication GO:0010648 158 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
protein complex subunit organization GO:0071822 302 0.021
chromosome condensation GO:0030261 3 0.021
amine metabolic process GO:0009308 38 0.021
organophosphate metabolic process GO:0019637 370 0.021
regulation of mitotic cell cycle phase transition GO:1901990 11 0.021
regulation of cellular response to stress GO:0080135 49 0.021
reproduction GO:0000003 245 0.021
cell cell signaling GO:0007267 335 0.021
response to nutrient GO:0007584 248 0.021
central nervous system development GO:0007417 311 0.020
response to peptide GO:1901652 292 0.020
regulation of signal transduction GO:0009966 318 0.020
nuclear transport GO:0051169 49 0.020
spermatogenesis GO:0007283 99 0.020
response to purine containing compound GO:0014074 126 0.020
mitotic cell cycle phase transition GO:0044772 20 0.020
chemical homeostasis GO:0048878 292 0.020
organ regeneration GO:0031100 101 0.020
response to growth factor GO:0070848 189 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
response to oxygen levels GO:0070482 265 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
response to peptide hormone GO:0043434 278 0.019
negative regulation of rna metabolic process GO:0051253 123 0.019
regulation of transferase activity GO:0051338 123 0.019
response to light stimulus GO:0009416 52 0.019
cardiovascular system development GO:0072358 134 0.019
covalent chromatin modification GO:0016569 30 0.019
sexual reproduction GO:0019953 148 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
positive regulation of apoptotic process GO:0043065 154 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
chromatin remodeling GO:0006338 3 0.018
cellular macromolecule localization GO:0070727 122 0.018
gland development GO:0048732 155 0.018
regulation of kinase activity GO:0043549 117 0.018
dna replication GO:0006260 37 0.018
response to ethanol GO:0045471 162 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
microtubule based process GO:0007017 36 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
positive regulation of cellular catabolic process GO:0031331 71 0.017
developmental process involved in reproduction GO:0003006 159 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
homeostatic process GO:0042592 331 0.017
regulation of gene expression epigenetic GO:0040029 10 0.016
dna integrity checkpoint GO:0031570 2 0.016
nucleotide metabolic process GO:0009117 279 0.016
response to organophosphorus GO:0046683 102 0.016
heterocycle catabolic process GO:0046700 167 0.016
synaptic transmission GO:0007268 235 0.016
regulation of apoptotic process GO:0042981 335 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
negative regulation of cell division GO:0051782 1 0.016
regeneration GO:0031099 163 0.016
organelle fission GO:0048285 25 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
male gamete generation GO:0048232 99 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
reproductive system development GO:0061458 128 0.016
response to vitamin GO:0033273 131 0.015
single organism catabolic process GO:0044712 283 0.015
response to monosaccharide GO:0034284 159 0.015
axis specification GO:0009798 4 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
nitrogen compound transport GO:0071705 229 0.015
rhythmic process GO:0048511 156 0.015
activation of cysteine type endopeptidase activity GO:0097202 4 0.015
growth GO:0040007 165 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
cell cycle process GO:0022402 57 0.014
cellular response to external stimulus GO:0071496 118 0.014
response to estradiol GO:0032355 164 0.014
positive regulation of proteasomal protein catabolic process GO:1901800 3 0.014
vesicle mediated transport GO:0016192 181 0.014
cell motility GO:0048870 202 0.014
histone phosphorylation GO:0016572 6 0.014
regulation of neurogenesis GO:0050767 247 0.014
regulation of protein kinase activity GO:0045859 105 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
aromatic compound catabolic process GO:0019439 168 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
sex differentiation GO:0007548 113 0.013
negative regulation of protein modification process GO:0031400 52 0.013
ion homeostasis GO:0050801 212 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
regulation of neuron projection development GO:0010975 161 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
rna localization GO:0006403 4 0.013
cytoskeleton dependent cytokinesis GO:0061640 2 0.013
heart development GO:0007507 72 0.013
chromosome separation GO:0051304 1 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.013
cellular component movement GO:0006928 248 0.012
behavior GO:0007610 205 0.012
purine containing compound catabolic process GO:0072523 138 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
regulation of proteolysis GO:0030162 66 0.012
mitotic cell cycle checkpoint GO:0007093 1 0.012
intracellular signal transduction GO:0035556 314 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
double strand break repair GO:0006302 1 0.012
negative regulation of cell death GO:0060548 229 0.012
positive regulation of catabolic process GO:0009896 78 0.012
cell morphogenesis GO:0000902 142 0.012
positive regulation of cell death GO:0010942 184 0.012
nucleoside metabolic process GO:0009116 179 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
response to uv GO:0009411 8 0.012
mitotic spindle organization GO:0007052 2 0.012
intracellular transport GO:0046907 185 0.012
cellular response to lipid GO:0071396 201 0.012
centrosome cycle GO:0007098 1 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
neuron projection morphogenesis GO:0048812 122 0.011
response to ketone GO:1901654 182 0.011
regulation of membrane potential GO:0042391 110 0.011
ras protein signal transduction GO:0007265 29 0.011
pteridine containing compound metabolic process GO:0042558 14 0.011
learning or memory GO:0007611 90 0.011
regulation of catalytic activity GO:0050790 304 0.011
nucleoside catabolic process GO:0009164 126 0.011
regulation of nervous system development GO:0051960 264 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
regulation of dna metabolic process GO:0051052 60 0.011
negative regulation of nuclear division GO:0051784 1 0.011
cellular chemical homeostasis GO:0055082 247 0.011
positive regulation of cytoplasmic transport GO:1903651 32 0.011
gonad development GO:0008406 104 0.011
centrosome organization GO:0051297 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
negative regulation of protein maturation GO:1903318 47 0.011
meiotic nuclear division GO:0007126 8 0.011
response to corticosteroid GO:0031960 235 0.010
developmental growth GO:0048589 100 0.010
secretion GO:0046903 307 0.010
negative regulation of developmental process GO:0051093 125 0.010
mitotic sister chromatid separation GO:0051306 1 0.010
positive regulation of dna metabolic process GO:0051054 39 0.010
neurological system process GO:0050877 219 0.010
regulation of protein maturation GO:1903317 50 0.010
positive regulation of phosphorylation GO:0042327 177 0.010

Mcm7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.043
disease of cellular proliferation DOID:14566 0 0.043
organ system cancer DOID:0050686 0 0.043
gastrointestinal system cancer DOID:3119 0 0.039
intestinal cancer DOID:10155 0 0.039
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
large intestine cancer DOID:5672 0 0.011