Rattus norvegicus

7 known processes

Mcpt4

mast cell protease 4

Mcpt4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.273
Rat
regulation of catalytic activity GO:0050790 304 0.218
homeostatic process GO:0042592 331 0.156
positive regulation of molecular function GO:0044093 230 0.118
response to hexose GO:0009746 144 0.114
synaptic vesicle amine transport GO:0015842 3 0.114
regulation of molecular function GO:0065009 398 0.111
chemical homeostasis GO:0048878 292 0.105
positive regulation of biosynthetic process GO:0009891 319 0.103
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.102
divalent metal ion transport GO:0070838 132 0.100
response to decreased oxygen levels GO:0036293 237 0.090
response to inorganic substance GO:0010035 377 0.087
organic cyclic compound catabolic process GO:1901361 175 0.085
regulation of phosphorus metabolic process GO:0051174 349 0.084
cellular response to hormone stimulus GO:0032870 247 0.079
cellular ion homeostasis GO:0006873 184 0.078
carboxylic acid metabolic process GO:0019752 289 0.077
regulation of cellular protein metabolic process GO:0032268 267 0.071
single organism catabolic process GO:0044712 283 0.068
regulation of secretion GO:0051046 224 0.067
positive regulation of catalytic activity GO:0043085 184 0.066
regulation of blood pressure GO:0008217 83 0.065
glycosyl compound metabolic process GO:1901657 182 0.065
purine ribonucleoside metabolic process GO:0046128 168 0.065
cellular homeostasis GO:0019725 252 0.065
transmembrane transport GO:0055085 412 0.064
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.062
ribonucleoside metabolic process GO:0009119 174 0.062
extracellular matrix constituent secretion GO:0070278 4 0.061
response to carbohydrate GO:0009743 183 0.061
cellular chemical homeostasis GO:0055082 247 0.058
defense response GO:0006952 194 0.057
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.057
cellular amino acid metabolic process GO:0006520 107 0.057
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.056
regulation of protein metabolic process GO:0051246 289 0.055
positive regulation of nucleoside metabolic process GO:0045979 55 0.055
purine nucleoside triphosphate metabolic process GO:0009144 141 0.054
reproductive process GO:0022414 372 0.053
nucleoside metabolic process GO:0009116 179 0.053
guanosine containing compound metabolic process GO:1901068 74 0.052
regulation of cell proliferation GO:0042127 359 0.052
ras protein signal transduction GO:0007265 29 0.052
regulation of rna biosynthetic process GO:2001141 381 0.051
regulation of nucleotide metabolic process GO:0006140 117 0.050
organic substance catabolic process GO:1901575 316 0.050
apoptotic process GO:0006915 381 0.049
purine nucleoside catabolic process GO:0006152 124 0.048
organophosphate catabolic process GO:0046434 148 0.048
purine nucleoside triphosphate catabolic process GO:0009146 122 0.047
intracellular signal transduction GO:0035556 314 0.046
gtp catabolic process GO:0006184 71 0.046
growth GO:0040007 165 0.046
cellular response to endogenous stimulus GO:0071495 377 0.045
regulation of multicellular organismal development GO:2000026 376 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
guanosine containing compound catabolic process GO:1901069 71 0.043
cation transport GO:0006812 382 0.043
glycosyl compound catabolic process GO:1901658 126 0.043
circulatory system process GO:0003013 183 0.042
positive regulation of cell proliferation GO:0008284 249 0.042
purine nucleoside metabolic process GO:0042278 169 0.041
small gtpase mediated signal transduction GO:0007264 36 0.041
response to antibiotic GO:0046677 39 0.040
regulation of hydrolase activity GO:0051336 143 0.040
ribonucleoside catabolic process GO:0042454 126 0.039
purine ribonucleoside catabolic process GO:0046130 124 0.039
regulation of system process GO:0044057 208 0.038
oxoacid metabolic process GO:0043436 290 0.038
regulation of gtpase activity GO:0043087 57 0.038
positive regulation of gtpase activity GO:0043547 47 0.038
hormone biosynthetic process GO:0042446 25 0.038
ion homeostasis GO:0050801 212 0.037
organic acid biosynthetic process GO:0016053 83 0.037
cell projection organization GO:0030030 302 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
cellular metal ion homeostasis GO:0006875 172 0.036
negative regulation of cellular metabolic process GO:0031324 281 0.036
nucleoside phosphate catabolic process GO:1901292 140 0.036
organic acid metabolic process GO:0006082 292 0.035
ribonucleotide catabolic process GO:0009261 136 0.035
response to glucose GO:0009749 136 0.035
positive regulation of hydrolase activity GO:0051345 86 0.035
single organism intracellular transport GO:1902582 166 0.035
metal ion homeostasis GO:0055065 186 0.034
protein complex biogenesis GO:0070271 263 0.033
response to herbicide GO:0009635 16 0.033
cellular response to stress GO:0033554 269 0.033
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.033
positive regulation of nucleotide metabolic process GO:0045981 91 0.032
response to glucocorticoid GO:0051384 223 0.032
response to hypoxia GO:0001666 231 0.032
regulation of nucleoside metabolic process GO:0009118 66 0.032
blood circulation GO:0008015 183 0.032
cellular ketone metabolic process GO:0042180 51 0.032
immune response to tumor cell GO:0002418 3 0.032
nucleic acid templated transcription GO:0097659 379 0.032
ribonucleoside triphosphate catabolic process GO:0009203 122 0.031
cellular cation homeostasis GO:0030003 180 0.031
steroid biosynthetic process GO:0006694 48 0.031
nucleotide catabolic process GO:0009166 139 0.031
nucleoside catabolic process GO:0009164 126 0.030
rna biosynthetic process GO:0032774 380 0.030
response to monosaccharide GO:0034284 159 0.030
ribonucleoside triphosphate metabolic process GO:0009199 141 0.030
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.029
purine nucleotide catabolic process GO:0006195 136 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.029
nucleobase containing compound catabolic process GO:0034655 152 0.029
multi multicellular organism process GO:0044706 138 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
brain development GO:0007420 247 0.029
ion transmembrane transport GO:0034220 365 0.029
intracellular transport GO:0046907 185 0.029
purine ribonucleotide catabolic process GO:0009154 136 0.028
secretion by cell GO:0032940 248 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.028
cell growth GO:0016049 104 0.028
central nervous system development GO:0007417 311 0.028
negative regulation of immune response to tumor cell GO:0002838 2 0.028
developmental process involved in reproduction GO:0003006 159 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.027
positive regulation of gene expression GO:0010628 244 0.027
nucleoside triphosphate metabolic process GO:0009141 144 0.027
cellular sodium ion homeostasis GO:0006883 4 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
nucleoside triphosphate catabolic process GO:0009143 123 0.027
negative regulation of molecular function GO:0044092 133 0.027
regulation of signal transduction GO:0009966 318 0.026
response to chromate GO:0046687 3 0.026
purine containing compound metabolic process GO:0072521 253 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.025
regulation of purine nucleotide catabolic process GO:0033121 65 0.025
regulation of ras protein signal transduction GO:0046578 45 0.025
regulation of cellular catabolic process GO:0031329 101 0.025
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
regulation of blood circulation GO:1903522 110 0.024
leukocyte cell cell adhesion GO:0007159 4 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
gtp metabolic process GO:0046039 72 0.024
negative regulation of metabolic process GO:0009892 331 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.024
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.023
protein phosphorylation GO:0006468 345 0.023
metal ion transport GO:0030001 289 0.023
chromosome segregation GO:0007059 2 0.023
regulation of phosphorylation GO:0042325 248 0.022
positive regulation of protein modification process GO:0031401 142 0.022
urogenital system development GO:0001655 78 0.022
regulation of protein modification process GO:0031399 194 0.022
cellular catabolic process GO:0044248 295 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
positive regulation of cell communication GO:0010647 271 0.022
neurological system process GO:0050877 219 0.022
anterior posterior pattern specification GO:0009952 1 0.022
negative regulation of cellular protein metabolic process GO:0032269 106 0.022
muscle system process GO:0003012 115 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
response to tumor cell GO:0002347 4 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
positive regulation of multicellular organismal process GO:0051240 387 0.021
heterocycle catabolic process GO:0046700 167 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
positive regulation of developmental process GO:0051094 283 0.021
regulation of extracellular matrix constituent secretion GO:0003330 2 0.021
response to peptide GO:1901652 292 0.021
regulation of programmed cell death GO:0043067 341 0.021
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
regulation of nervous system development GO:0051960 264 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
aromatic compound catabolic process GO:0019439 168 0.020
proteolysis GO:0006508 175 0.020
lipid biosynthetic process GO:0008610 128 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
negative regulation of serine type endopeptidase activity GO:1900004 1 0.020
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.020
regulation of nucleotide catabolic process GO:0030811 65 0.020
response to extracellular stimulus GO:0009991 380 0.020
regulation of immune system process GO:0002682 123 0.020
endocrine process GO:0050886 32 0.020
regulation of serine type peptidase activity GO:1902571 1 0.020
response to biotic stimulus GO:0009607 226 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
glucose homeostasis GO:0042593 75 0.020
calcium ion homeostasis GO:0055074 162 0.019
regulation of small gtpase mediated signal transduction GO:0051056 48 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
positive regulation of extracellular matrix organization GO:1903055 4 0.019
regulation of immune response to tumor cell GO:0002837 3 0.019
multicellular organism reproduction GO:0032504 233 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
response to nutrient levels GO:0031667 370 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
cation transmembrane transport GO:0098655 263 0.018
protein oligomerization GO:0051259 191 0.018
response to oxygen levels GO:0070482 265 0.018
negative regulation of gene expression GO:0010629 199 0.018
tissue development GO:0009888 252 0.018
chromosome separation GO:0051304 1 0.018
positive regulation of secretion GO:0051047 140 0.018
taxis GO:0042330 67 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
cellular component biogenesis GO:0044085 368 0.018
cation homeostasis GO:0055080 195 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
multicellular organismal signaling GO:0035637 44 0.018
regulation of metal ion transport GO:0010959 118 0.018
cellular calcium ion homeostasis GO:0006874 160 0.017
negative regulation of cell communication GO:0010648 158 0.017
regulation of protein kinase activity GO:0045859 105 0.017
response to acid chemical GO:0001101 222 0.017
positive regulation of cellular catabolic process GO:0031331 71 0.017
neuron projection development GO:0031175 273 0.017
negative regulation of response to tumor cell GO:0002835 2 0.017
mitotic sister chromatid separation GO:0051306 1 0.017
lipid transport GO:0006869 61 0.017
regulation of cellular component organization GO:0051128 368 0.017
response to estradiol GO:0032355 164 0.017
regulation of proteasomal protein catabolic process GO:0061136 4 0.017
non canonical wnt signaling pathway GO:0035567 3 0.017
regulation of catabolic process GO:0009894 113 0.017
divalent inorganic cation transport GO:0072511 134 0.017
immune system process GO:0002376 204 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
cellular amine metabolic process GO:0044106 38 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
muscle structure development GO:0061061 87 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
vasoconstriction GO:0042310 54 0.016
anatomical structure formation involved in morphogenesis GO:0048646 83 0.016
transcription dna templated GO:0006351 377 0.016
positive regulation of nucleotide catabolic process GO:0030813 53 0.016
negative regulation of developmental process GO:0051093 125 0.016
regulation of calcium ion transport GO:0051924 77 0.016
aging GO:0007568 241 0.016
cellular response to hexose stimulus GO:0071331 65 0.016
regulation of transcription dna templated GO:0006355 374 0.016
c21 steroid hormone biosynthetic process GO:0006700 10 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
catabolic process GO:0009056 351 0.016
negative regulation of signaling GO:0023057 157 0.015
regulation of norepinephrine secretion GO:0014061 15 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
anatomical structure morphogenesis GO:0009653 298 0.015
tongue morphogenesis GO:0043587 3 0.015
stress activated mapk cascade GO:0051403 35 0.015
regulation of cell growth GO:0001558 85 0.015
single organism reproductive process GO:0044702 297 0.015
sensory perception of pain GO:0019233 73 0.015
amine metabolic process GO:0009308 38 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
steroid metabolic process GO:0008202 73 0.015
regulation of anatomical structure size GO:0090066 135 0.015
multicellular organismal water homeostasis GO:0050891 4 0.015
response to vitamin a GO:0033189 36 0.015
response to hydrogen peroxide GO:0042542 89 0.015
secretion GO:0046903 307 0.015
sensory organ development GO:0007423 74 0.015
cell cell signaling GO:0007267 335 0.015
response to external biotic stimulus GO:0043207 221 0.015
calcium ion transport GO:0006816 131 0.014
cellular response to corticosteroid stimulus GO:0071384 69 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
sex differentiation GO:0007548 113 0.014
cellular macromolecule localization GO:0070727 122 0.014
male gonad development GO:0008584 59 0.014
response to acetate GO:0010034 3 0.014
small molecule biosynthetic process GO:0044283 124 0.014
protein homotrimerization GO:0070207 15 0.014
cellular response to peptide GO:1901653 133 0.014
response to toxic substance GO:0009636 133 0.014
positive regulation of transferase activity GO:0051347 81 0.014
male sex differentiation GO:0046661 64 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
gland development GO:0048732 155 0.014
axis specification GO:0009798 4 0.014
negative regulation of organ growth GO:0046621 3 0.014
positive regulation of blood circulation GO:1903524 65 0.014
intestinal absorption GO:0050892 3 0.014
reproductive system development GO:0061458 128 0.013
response to fluoride GO:1902617 3 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
response to nutrient GO:0007584 248 0.013
vasculature development GO:0001944 70 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
hormone metabolic process GO:0042445 69 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
response to other organism GO:0051707 220 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
organic hydroxy compound transport GO:0015850 77 0.013
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
regulation of hormone levels GO:0010817 187 0.013
negative regulation of serine type peptidase activity GO:1902572 1 0.013
rho protein signal transduction GO:0007266 11 0.013
organophosphate metabolic process GO:0019637 370 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
regulation of cell differentiation GO:0045595 320 0.013
regulation of transferase activity GO:0051338 123 0.013
response to organophosphorus GO:0046683 102 0.013
organelle organization GO:0006996 266 0.013
negative regulation of innate immune response GO:0045824 4 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.013
negative regulation of response to stimulus GO:0048585 155 0.012
regulation of serine type endopeptidase activity GO:1900003 1 0.012
development of primary sexual characteristics GO:0045137 107 0.012
cellular component assembly GO:0022607 360 0.012
regulation of lipid biosynthetic process GO:0046890 38 0.012
regulation of rna metabolic process GO:0051252 391 0.012
response to estrogen GO:0043627 232 0.012
response to corticosterone GO:0051412 40 0.012
positive regulation of transport GO:0051050 245 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
embryonic axis specification GO:0000578 1 0.012
vesicle mediated transport GO:0016192 181 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
limbic system development GO:0021761 38 0.012
tube development GO:0035295 89 0.012
membrane repolarization GO:0086009 1 0.012
protein localization GO:0008104 191 0.011
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of vasculature development GO:1901342 44 0.011
sterol homeostasis GO:0055092 3 0.011
chemotaxis GO:0006935 66 0.011
response to fungicide GO:0060992 20 0.011
cellular response to carbohydrate stimulus GO:0071322 72 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.011
regulation of immune response GO:0050776 55 0.011
anion transport GO:0006820 178 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
gonad development GO:0008406 104 0.011
dna integrity checkpoint GO:0031570 2 0.011
male mating behavior GO:0060179 3 0.011
grooming behavior GO:0007625 4 0.011
cellular glucose homeostasis GO:0001678 66 0.011
purine containing compound catabolic process GO:0072523 138 0.011
male gamete generation GO:0048232 99 0.011
regulation of smoothened signaling pathway GO:0008589 2 0.011
reproductive structure development GO:0048608 128 0.010
cell fate determination GO:0001709 2 0.010
positive regulation of calcium ion transport GO:0051928 36 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
regulation of gtp catabolic process GO:0033124 58 0.010
head development GO:0060322 247 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of proteolysis GO:0030162 66 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
insecticide metabolic process GO:0017143 4 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
hormone transport GO:0009914 121 0.010
sexual reproduction GO:0019953 148 0.010
behavior GO:0007610 205 0.010
protein maturation GO:0051604 68 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
positive regulation of alpha beta t cell activation GO:0046635 2 0.010
reactive oxygen species metabolic process GO:0072593 37 0.010

Mcpt4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.041
respiratory system disease DOID:1579 0 0.030
lower respiratory tract disease DOID:0050161 0 0.030
sensory system disease DOID:0050155 0 0.029
cardiovascular system disease DOID:1287 0 0.025
disease of metabolism DOID:0014667 0 0.018
urinary system disease DOID:18 0 0.013
long qt syndrome DOID:2843 0 0.012
heart conduction disease DOID:10273 0 0.011
familial atrial fibrillation DOID:0050650 0 0.011
acquired metabolic disease DOID:0060158 0 0.011