Rattus norvegicus

43 known processes

Mdh2

malate dehydrogenase 2, NAD (mitochondrial)

(Aliases: Mor1)

Mdh2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nadh metabolic process GO:0006734 10 0.786
generation of precursor metabolites and energy GO:0006091 62 0.758
nucleobase containing small molecule metabolic process GO:0055086 316 0.660
tricarboxylic acid metabolic process GO:0072350 10 0.605
carboxylic acid metabolic process GO:0019752 289 0.473
nicotinamide nucleotide metabolic process GO:0046496 28 0.467
organic acid metabolic process GO:0006082 292 0.465
purine ribonucleoside diphosphate biosynthetic process GO:0009180 9 0.447
aerobic respiration GO:0009060 13 0.428
dicarboxylic acid metabolic process GO:0043648 42 0.424
oxidation reduction process GO:0055114 304 0.420
oxoacid metabolic process GO:0043436 290 0.333
nucleoside triphosphate metabolic process GO:0009141 144 0.312
single organism biosynthetic process GO:0044711 342 0.304
ribonucleoside triphosphate metabolic process GO:0009199 141 0.301
organophosphate metabolic process GO:0019637 370 0.281
purine nucleoside metabolic process GO:0042278 169 0.272
purine nucleoside monophosphate metabolic process GO:0009126 84 0.269
purine nucleoside triphosphate metabolic process GO:0009144 141 0.269
nad metabolic process GO:0019674 15 0.266
nucleotide metabolic process GO:0009117 279 0.264
ribonucleotide metabolic process GO:0009259 231 0.262
glutamine family amino acid biosynthetic process GO:0009084 2 0.258
nucleoside monophosphate metabolic process GO:0009123 93 0.232
purine nucleoside biosynthetic process GO:0042451 21 0.221
pyridine containing compound metabolic process GO:0072524 32 0.220
organic substance catabolic process GO:1901575 316 0.214
atp metabolic process GO:0046034 72 0.200
energy derivation by oxidation of organic compounds GO:0015980 46 0.193
isocitrate metabolic process GO:0006102 5 0.191
citrate metabolic process GO:0006101 3 0.189
purine nucleotide metabolic process GO:0006163 229 0.162
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.162
nucleoside phosphate metabolic process GO:0006753 283 0.141
catabolic process GO:0009056 351 0.134
single organism catabolic process GO:0044712 283 0.129
purine containing compound metabolic process GO:0072521 253 0.123
glycosyl compound metabolic process GO:1901657 182 0.123
purine ribonucleotide metabolic process GO:0009150 227 0.119
organonitrogen compound catabolic process GO:1901565 179 0.119
coenzyme metabolic process GO:0006732 86 0.113
purine ribonucleoside monophosphate biosynthetic process GO:0009168 20 0.108
ribonucleoside metabolic process GO:0009119 174 0.098
cellular catabolic process GO:0044248 295 0.094
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.089
nucleoside metabolic process GO:0009116 179 0.089
monocarboxylic acid metabolic process GO:0032787 152 0.086
cellular respiration GO:0045333 21 0.086
purine ribonucleoside metabolic process GO:0046128 168 0.083
multicellular organism reproduction GO:0032504 233 0.075
carbohydrate derivative metabolic process GO:1901135 346 0.074
cell cell signaling GO:0007267 335 0.071
porphyrin containing compound biosynthetic process GO:0006779 6 0.069
purine containing compound catabolic process GO:0072523 138 0.066
response to extracellular stimulus GO:0009991 380 0.066
pyridine nucleotide metabolic process GO:0019362 28 0.066
atp catabolic process GO:0006200 54 0.064
response to oxidative stress GO:0006979 186 0.064
reproductive process GO:0022414 372 0.060
response to peptide GO:1901652 292 0.059
response to peptide hormone GO:0043434 278 0.058
multi organism reproductive process GO:0044703 262 0.054
cofactor metabolic process GO:0051186 95 0.052
ribonucleoside monophosphate metabolic process GO:0009161 88 0.048
glutamate catabolic process GO:0006538 1 0.048
cation homeostasis GO:0055080 195 0.047
ribonucleotide catabolic process GO:0009261 136 0.047
ribose phosphate biosynthetic process GO:0046390 87 0.046
regulation of apoptotic process GO:0042981 335 0.046
Fly
nucleotide catabolic process GO:0009166 139 0.044
monovalent inorganic cation transport GO:0015672 172 0.041
cellular metal ion homeostasis GO:0006875 172 0.041
purine ribonucleoside biosynthetic process GO:0046129 21 0.040
tricarboxylic acid cycle GO:0006099 11 0.040
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.040
single organism reproductive process GO:0044702 297 0.039
organonitrogen compound biosynthetic process GO:1901566 167 0.039
nucleoside phosphate catabolic process GO:1901292 140 0.039
response to toxic substance GO:0009636 133 0.038
organophosphate catabolic process GO:0046434 148 0.038
monosaccharide metabolic process GO:0005996 61 0.038
glycosyl compound catabolic process GO:1901658 126 0.038
purine ribonucleotide biosynthetic process GO:0009152 81 0.038
transmembrane transport GO:0055085 412 0.038
organelle organization GO:0006996 266 0.036
developmental process involved in reproduction GO:0003006 159 0.035
nucleoside monophosphate biosynthetic process GO:0009124 28 0.035
purine ribonucleoside catabolic process GO:0046130 124 0.035
cation transport GO:0006812 382 0.035
vesicle mediated transport GO:0016192 181 0.034
purine nucleoside diphosphate biosynthetic process GO:0009136 9 0.033
purine nucleoside catabolic process GO:0006152 124 0.033
adp biosynthetic process GO:0006172 8 0.033
cellular amino acid biosynthetic process GO:0008652 32 0.032
development of primary sexual characteristics GO:0045137 107 0.032
ribonucleotide biosynthetic process GO:0009260 85 0.032
cellular component assembly GO:0022607 360 0.031
purine ribonucleotide catabolic process GO:0009154 136 0.031
rna metabolic process GO:0016070 406 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.031
chemical homeostasis GO:0048878 292 0.031
nucleoside diphosphate biosynthetic process GO:0009133 12 0.031
response to decreased oxygen levels GO:0036293 237 0.030
proteolysis GO:0006508 175 0.030
Fly
ribonucleoside biosynthetic process GO:0042455 25 0.030
regulation of signal transduction GO:0009966 318 0.029
single organism organelle organization GO:1902589 180 0.028
reproduction GO:0000003 245 0.028
cell motility GO:0048870 202 0.027
inorganic ion transmembrane transport GO:0098660 229 0.026
metal ion homeostasis GO:0055065 186 0.025
transcription dna templated GO:0006351 377 0.025
response to ethanol GO:0045471 162 0.025
cellular component biogenesis GO:0044085 368 0.024
cellular ion homeostasis GO:0006873 184 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
Fly
carbohydrate derivative biosynthetic process GO:1901137 124 0.024
oxidoreduction coenzyme metabolic process GO:0006733 31 0.024
gamete generation GO:0007276 124 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
cation transmembrane transport GO:0098655 263 0.023
head development GO:0060322 247 0.023
purine nucleotide catabolic process GO:0006195 136 0.023
ossification GO:0001503 70 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
organophosphate biosynthetic process GO:0090407 143 0.022
aromatic compound catabolic process GO:0019439 168 0.022
positive regulation of molecular function GO:0044093 230 0.022
Fly
ion homeostasis GO:0050801 212 0.022
syncytium formation by plasma membrane fusion GO:0000768 3 0.021
cellular chemical homeostasis GO:0055082 247 0.021
protein complex subunit organization GO:0071822 302 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
central nervous system development GO:0007417 311 0.021
reproductive structure development GO:0048608 128 0.021
purine nucleotide biosynthetic process GO:0006164 83 0.021
anatomical structure formation involved in morphogenesis GO:0048646 83 0.021
response to ketone GO:1901654 182 0.020
response to alkaloid GO:0043279 132 0.020
heterocycle catabolic process GO:0046700 167 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.020
response to nutrient levels GO:0031667 370 0.020
macromolecule localization GO:0033036 252 0.020
synaptic transmission GO:0007268 235 0.020
locomotion GO:0040011 237 0.020
cellular response to stress GO:0033554 269 0.020
single organism carbohydrate metabolic process GO:0044723 118 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.019
cell migration GO:0016477 197 0.019
nucleoside catabolic process GO:0009164 126 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
response to corticosteroid GO:0031960 235 0.019
2 oxoglutarate metabolic process GO:0006103 6 0.019
ion transmembrane transport GO:0034220 365 0.019
regulation of cell proliferation GO:0042127 359 0.018
dicarboxylic acid catabolic process GO:0043649 1 0.018
ribonucleoside triphosphate catabolic process GO:0009203 122 0.018
response to nutrient GO:0007584 248 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
maintenance of location GO:0051235 17 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
response to activity GO:0014823 73 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
cell cell signaling involved in cell fate commitment GO:0045168 2 0.017
ribose phosphate metabolic process GO:0019693 235 0.016
cellular cation homeostasis GO:0030003 180 0.016
organic acid biosynthetic process GO:0016053 83 0.016
carbohydrate metabolic process GO:0005975 130 0.016
secretion GO:0046903 307 0.016
adp metabolic process GO:0046031 8 0.016
intracellular transport GO:0046907 185 0.016
protein localization to endoplasmic reticulum GO:0070972 1 0.015
cellular homeostasis GO:0019725 252 0.015
ribonucleoside diphosphate metabolic process GO:0009185 10 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
negative regulation of neuron death GO:1901215 69 0.015
metal ion transport GO:0030001 289 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
nucleoside monophosphate catabolic process GO:0009125 56 0.015
behavior GO:0007610 205 0.015
negative regulation of cell death GO:0060548 229 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
cellular response to oxygen containing compound GO:1901701 386 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
purine ribonucleoside diphosphate metabolic process GO:0009179 9 0.014
intracellular signal transduction GO:0035556 314 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
cellular amine metabolic process GO:0044106 38 0.013
negative regulation of metabolic process GO:0009892 331 0.013
cell cycle checkpoint GO:0000075 2 0.013
protein complex assembly GO:0006461 263 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
protein complex biogenesis GO:0070271 263 0.012
response to reactive oxygen species GO:0000302 120 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
endocytosis GO:0006897 84 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
homeostatic process GO:0042592 331 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
response to mineralocorticoid GO:0051385 49 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
blood vessel development GO:0001568 69 0.012
regulation of catalytic activity GO:0050790 304 0.012
Fly
spermatogenesis GO:0007283 99 0.012
macromolecular complex assembly GO:0065003 273 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
negative regulation of autophagy GO:0010507 1 0.012
cytoplasmic transport GO:0016482 115 0.012
small molecule biosynthetic process GO:0044283 124 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
liver development GO:0001889 90 0.011
localization of cell GO:0051674 202 0.011
calcium ion homeostasis GO:0055074 162 0.011
reproductive system development GO:0061458 128 0.011
regulation of multicellular organismal development GO:2000026 376 0.011
negative regulation of cell communication GO:0010648 158 0.011
myoblast fusion GO:0007520 2 0.011
cardiovascular system development GO:0072358 134 0.011
lipid storage GO:0019915 1 0.011
sex differentiation GO:0007548 113 0.011
electron transport chain GO:0022900 5 0.011
alpha amino acid metabolic process GO:1901605 71 0.011
response to hexose GO:0009746 144 0.011
negative regulation of protein modification by small protein conjugation or removal GO:1903321 4 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
apoptotic process GO:0006915 381 0.011
Fly
negative regulation of signaling GO:0023057 157 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
regulation of growth GO:0040008 105 0.010
protein processing GO:0016485 68 0.010
Fly
calcium ion transport GO:0006816 131 0.010
response to organophosphorus GO:0046683 102 0.010
triglyceride homeostasis GO:0070328 2 0.010
nucleoside diphosphate metabolic process GO:0009132 14 0.010

Mdh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
central nervous system disease DOID:331 0 0.026