Rattus norvegicus

0 known processes

Mll5

myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

Mll5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.586
Human
regulation of transcription dna templated GO:0006355 374 0.415
Human
rna biosynthetic process GO:0032774 380 0.341
Human
positive regulation of gene expression GO:0010628 244 0.268
Human
rna metabolic process GO:0016070 406 0.264
Human
nucleic acid templated transcription GO:0097659 379 0.231
Human
positive regulation of nucleic acid templated transcription GO:1903508 197 0.229
Human
positive regulation of rna metabolic process GO:0051254 203 0.201
Human
positive regulation of cellular biosynthetic process GO:0031328 295 0.196
Human
macromolecular complex subunit organization GO:0043933 339 0.191
Human
transcription dna templated GO:0006351 377 0.173
Human
positive regulation of biosynthetic process GO:0009891 319 0.166
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.147
regulation of programmed cell death GO:0043067 341 0.133
regulation of nucleic acid templated transcription GO:1903506 380 0.121
Human
multi organism reproductive process GO:0044703 262 0.120
multicellular organismal reproductive process GO:0048609 233 0.119
positive regulation of rna biosynthetic process GO:1902680 197 0.114
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.111
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.110
Human
negative regulation of rna metabolic process GO:0051253 123 0.108
reproduction GO:0000003 245 0.097
multicellular organism reproduction GO:0032504 233 0.094
positive regulation of programmed cell death GO:0043068 157 0.087
positive regulation of cell death GO:0010942 184 0.082
single organism reproductive process GO:0044702 297 0.082
positive regulation of response to stimulus GO:0048584 285 0.081
transcription from rna polymerase ii promoter GO:0006366 252 0.077
eye development GO:0001654 50 0.071
brain development GO:0007420 247 0.068
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.068
Human
protein complex subunit organization GO:0071822 302 0.068
organic acid metabolic process GO:0006082 292 0.064
regulation of apoptotic process GO:0042981 335 0.063
central nervous system development GO:0007417 311 0.060
cellular component biogenesis GO:0044085 368 0.057
positive regulation of transcription dna templated GO:0045893 197 0.057
Human
forebrain development GO:0030900 98 0.056
single organism organelle organization GO:1902589 180 0.055
Human
regulation of molecular function GO:0065009 398 0.054
tissue development GO:0009888 252 0.054
cellular component assembly GO:0022607 360 0.053
positive regulation of apoptotic process GO:0043065 154 0.048
camera type eye development GO:0043010 48 0.047
cellular response to oxygen containing compound GO:1901701 386 0.046
Human
sexual reproduction GO:0019953 148 0.046
motor neuron axon guidance GO:0008045 1 0.043
negative regulation of transcription dna templated GO:0045892 116 0.043
organelle organization GO:0006996 266 0.042
Human
regulation of phosphorus metabolic process GO:0051174 349 0.040
glycoside transport GO:1901656 2 0.040
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.040
negative regulation of metabolic process GO:0009892 331 0.040
neuron death GO:0070997 127 0.040
regulation of rna biosynthetic process GO:2001141 381 0.039
Human
positive regulation of multicellular organismal process GO:0051240 387 0.038
Human
cellular response to lipid GO:0071396 201 0.037
Human
developmental process involved in reproduction GO:0003006 159 0.037
response to biotic stimulus GO:0009607 226 0.036
neuron apoptotic process GO:0051402 88 0.035
reproductive process GO:0022414 372 0.034
carboxylic acid metabolic process GO:0019752 289 0.033
head development GO:0060322 247 0.033
calcium ion export GO:1901660 6 0.032
positive regulation of phosphorus metabolic process GO:0010562 262 0.032
response to wounding GO:0009611 254 0.032
regulation of calcineurin nfat signaling cascade GO:0070884 3 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
gland development GO:0048732 155 0.031
sensory organ development GO:0007423 74 0.030
regulation of protein localization GO:0032880 81 0.029
cellular response to hormone stimulus GO:0032870 247 0.029
regulation of extent of cell growth GO:0061387 25 0.029
synaptic transmission GO:0007268 235 0.029
growth GO:0040007 165 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
cytosolic calcium ion homeostasis GO:0051480 140 0.029
locomotion GO:0040011 237 0.029
regulation of multicellular organismal development GO:2000026 376 0.028
Human
microtubule cytoskeleton organization GO:0000226 25 0.028
hippocampus development GO:0021766 30 0.028
regulation of phosphate metabolic process GO:0019220 349 0.026
neuron projection extension GO:1990138 26 0.025
male gamete generation GO:0048232 99 0.025
axonogenesis GO:0007409 71 0.025
regulation of signal transduction GO:0009966 318 0.025
regulation of cell differentiation GO:0045595 320 0.025
Human
chromatin remodeling GO:0006338 3 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.024
taxis GO:0042330 67 0.024
cell cell signaling GO:0007267 335 0.024
cellular response to endogenous stimulus GO:0071495 377 0.023
regulation of protein kinase activity GO:0045859 105 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
neuron projection development GO:0031175 273 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
telencephalon development GO:0021537 62 0.023
positive regulation of developmental process GO:0051094 283 0.023
Human
single organism biosynthetic process GO:0044711 342 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
cell type specific apoptotic process GO:0097285 134 0.022
programmed cell death GO:0012501 392 0.022
gamete generation GO:0007276 124 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
apoptotic process GO:0006915 381 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
regulation of synaptic transmission GO:0050804 141 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
calcineurin nfat signaling cascade GO:0033173 3 0.020
axon extension GO:0048675 26 0.020
regulation of catalytic activity GO:0050790 304 0.020
glandular epithelial cell differentiation GO:0002067 4 0.020
multicellular organism growth GO:0035264 1 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
epithelium development GO:0060429 96 0.020
retina development in camera type eye GO:0060041 27 0.020
regulation of axonogenesis GO:0050770 37 0.019
response to nutrient levels GO:0031667 370 0.019
macromolecular complex assembly GO:0065003 273 0.019
actin filament based process GO:0030029 86 0.019
spermatogenesis GO:0007283 99 0.019
axis specification GO:0009798 4 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
Human
oxoacid metabolic process GO:0043436 290 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.018
negative regulation of cell communication GO:0010648 158 0.018
negative regulation of cell death GO:0060548 229 0.018
ras protein signal transduction GO:0007265 29 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
negative regulation of gene expression GO:0010629 199 0.018
intracellular signal transduction GO:0035556 314 0.018
negative regulation of catalytic activity GO:0043086 103 0.017
regulation of growth GO:0040008 105 0.017
eye morphogenesis GO:0048592 4 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
cellular response to stress GO:0033554 269 0.017
spindle organization GO:0007051 2 0.017
gonad development GO:0008406 104 0.017
response to fungicide GO:0060992 20 0.017
cellular chemical homeostasis GO:0055082 247 0.017
cellular homeostasis GO:0019725 252 0.017
protein phosphorylation GO:0006468 345 0.016
cell growth GO:0016049 104 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
cell cycle GO:0007049 101 0.016
regulation of synaptic plasticity GO:0048167 70 0.016
cell projection organization GO:0030030 302 0.016
amine metabolic process GO:0009308 38 0.015
single organism catabolic process GO:0044712 283 0.015
cellular amine metabolic process GO:0044106 38 0.015
negative regulation of osteoblast differentiation GO:0045668 2 0.015
response to lipopolysaccharide GO:0032496 191 0.015
response to growth factor GO:0070848 189 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
aging GO:0007568 241 0.015
cell part morphogenesis GO:0032990 123 0.015
peptidyl amino acid modification GO:0018193 126 0.015
Human
cellular ketone metabolic process GO:0042180 51 0.015
cell morphogenesis GO:0000902 142 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
centrosome organization GO:0051297 1 0.015
response to cytokine GO:0034097 215 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
cellular response to molecule of bacterial origin GO:0071219 56 0.015
pallium development GO:0021543 42 0.015
small gtpase mediated signal transduction GO:0007264 36 0.014
regulation of neuron death GO:1901214 115 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
regulation of mitotic sister chromatid separation GO:0010965 1 0.014
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 3 0.014
cellular response to biotic stimulus GO:0071216 59 0.014
positive regulation of signal transduction GO:0009967 175 0.014
metal ion homeostasis GO:0055065 186 0.014
regulation of calcium mediated signaling GO:0050848 8 0.014
response to monosaccharide GO:0034284 159 0.013
proteolysis GO:0006508 175 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
neuron fate commitment GO:0048663 4 0.013
response to estrogen GO:0043627 232 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
positive regulation of sarcomere organization GO:0060298 2 0.013
homeostatic process GO:0042592 331 0.013
organophosphate metabolic process GO:0019637 370 0.013
protein complex assembly GO:0006461 263 0.013
protein complex biogenesis GO:0070271 263 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
secretion GO:0046903 307 0.013
rhythmic process GO:0048511 156 0.013
regulation of ras protein signal transduction GO:0046578 45 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
neuron differentiation GO:0030182 368 0.012
regulation of body fluid levels GO:0050878 90 0.012
regulation of hydrolase activity GO:0051336 143 0.012
negative regulation of molecular function GO:0044092 133 0.012
membrane organization GO:0061024 94 0.012
positive regulation of cell development GO:0010720 176 0.012
developmental growth involved in morphogenesis GO:0060560 33 0.012
regulation of chromosome segregation GO:0051983 1 0.012
tube development GO:0035295 89 0.012
positive regulation of molecular function GO:0044093 230 0.012
positive regulation of growth GO:0045927 55 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
response to axon injury GO:0048678 59 0.012
ion homeostasis GO:0050801 212 0.012
chromosome segregation GO:0007059 2 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
chemical homeostasis GO:0048878 292 0.011
neuron development GO:0048666 286 0.011
response to hexose GO:0009746 144 0.011
cellular response to external stimulus GO:0071496 118 0.011
positive regulation of protein modification process GO:0031401 142 0.011
chromatin organization GO:0006325 34 0.011
Human
cellular response to glucocorticoid stimulus GO:0071385 68 0.011
response to extracellular stimulus GO:0009991 380 0.011
regulation of response to wounding GO:1903034 69 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
regulation of cellular response to stress GO:0080135 49 0.011
response to glucocorticoid GO:0051384 223 0.011
positive regulation of defense response GO:0031349 37 0.011
response to oxidative stress GO:0006979 186 0.011
microtubule based process GO:0007017 36 0.011
developmental growth GO:0048589 100 0.011
microtubule organizing center organization GO:0031023 1 0.011
regulation of mitotic sister chromatid segregation GO:0033047 1 0.011
canalicular bile acid transport GO:0015722 5 0.010
regulation of neuronal synaptic plasticity GO:0048168 31 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
somatic stem cell maintenance GO:0035019 2 0.010
organic substance catabolic process GO:1901575 316 0.010
regulation of system process GO:0044057 208 0.010
regulation of kinase activity GO:0043549 117 0.010
regulation of axon extension GO:0030516 24 0.010
regulation of transferase activity GO:0051338 123 0.010
regulation of anatomical structure size GO:0090066 135 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
embryonic pattern specification GO:0009880 1 0.010
response to molecule of bacterial origin GO:0002237 194 0.010

Mll5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014