Rattus norvegicus

27 known processes

Mpdz

multiple PDZ domain protein

Mpdz biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cellular component movement GO:0051272 102 0.183
regulation of cell morphogenesis GO:0022604 77 0.166
nucleotide metabolic process GO:0009117 279 0.159
carbohydrate derivative metabolic process GO:1901135 346 0.123
regulation of cellular component organization GO:0051128 368 0.110
organelle organization GO:0006996 266 0.109
purine nucleotide metabolic process GO:0006163 229 0.105
rna metabolic process GO:0016070 406 0.105
negative regulation of cellular metabolic process GO:0031324 281 0.104
regulation of anatomical structure morphogenesis GO:0022603 141 0.092
nucleic acid templated transcription GO:0097659 379 0.091
glycosyl compound metabolic process GO:1901657 182 0.084
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.083
regulation of protein metabolic process GO:0051246 289 0.083
single organism catabolic process GO:0044712 283 0.082
transcription dna templated GO:0006351 377 0.081
ribonucleotide metabolic process GO:0009259 231 0.077
anatomical structure morphogenesis GO:0009653 298 0.072
carbohydrate derivative biosynthetic process GO:1901137 124 0.069
carbohydrate derivative catabolic process GO:1901136 147 0.069
purine containing compound catabolic process GO:0072523 138 0.068
purine nucleoside metabolic process GO:0042278 169 0.068
nucleobase containing small molecule metabolic process GO:0055086 316 0.068
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.066
aromatic compound catabolic process GO:0019439 168 0.066
central nervous system development GO:0007417 311 0.066
cellular response to oxygen containing compound GO:1901701 386 0.066
intracellular signal transduction GO:0035556 314 0.066
organophosphate metabolic process GO:0019637 370 0.066
ribose phosphate metabolic process GO:0019693 235 0.065
purine ribonucleotide metabolic process GO:0009150 227 0.062
regulation of rna metabolic process GO:0051252 391 0.059
positive regulation of multicellular organismal process GO:0051240 387 0.058
rna biosynthetic process GO:0032774 380 0.058
negative regulation of biosynthetic process GO:0009890 168 0.057
regulation of phosphorylation GO:0042325 248 0.057
ribonucleotide catabolic process GO:0009261 136 0.057
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.056
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.056
organonitrogen compound catabolic process GO:1901565 179 0.056
catabolic process GO:0009056 351 0.055
regulation of locomotion GO:0040012 148 0.055
organophosphate biosynthetic process GO:0090407 143 0.054
purine containing compound metabolic process GO:0072521 253 0.053
cell projection morphogenesis GO:0048858 123 0.052
regulation of phosphorus metabolic process GO:0051174 349 0.051
nucleoside phosphate catabolic process GO:1901292 140 0.050
negative regulation of cellular biosynthetic process GO:0031327 161 0.049
reproductive process GO:0022414 372 0.048
regulation of protein phosphorylation GO:0001932 183 0.048
cell projection organization GO:0030030 302 0.047
regulation of phosphate metabolic process GO:0019220 349 0.047
ribonucleoside triphosphate metabolic process GO:0009199 141 0.047
negative regulation of rna biosynthetic process GO:1902679 118 0.046
nucleoside metabolic process GO:0009116 179 0.046
regulation of cellular ketone metabolic process GO:0010565 27 0.046
regulation of purine nucleotide catabolic process GO:0033121 65 0.045
positive regulation of nucleoside metabolic process GO:0045979 55 0.045
behavior GO:0007610 205 0.045
positive regulation of developmental process GO:0051094 283 0.045
nucleoside triphosphate catabolic process GO:0009143 123 0.044
positive regulation of cell development GO:0010720 176 0.044
purine nucleoside triphosphate metabolic process GO:0009144 141 0.044
positive regulation of cell differentiation GO:0045597 217 0.044
macromolecular complex subunit organization GO:0043933 339 0.044
organic substance catabolic process GO:1901575 316 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
regulation of programmed cell death GO:0043067 341 0.043
regulation of transcription dna templated GO:0006355 374 0.042
purine nucleotide catabolic process GO:0006195 136 0.042
regulation of molecular function GO:0065009 398 0.042
dendrite development GO:0016358 72 0.042
programmed cell death GO:0012501 392 0.042
response to purine containing compound GO:0014074 126 0.041
regulation of catabolic process GO:0009894 113 0.041
protein localization to organelle GO:0033365 57 0.041
cell morphogenesis GO:0000902 142 0.040
regulation of cellular extravasation GO:0002691 2 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.040
regulation of catalytic activity GO:0050790 304 0.040
glycosyl compound catabolic process GO:1901658 126 0.040
response to oxidative stress GO:0006979 186 0.039
positive regulation of protein metabolic process GO:0051247 178 0.039
gtp catabolic process GO:0006184 71 0.039
positive regulation of cell migration GO:0030335 96 0.039
neuron projection development GO:0031175 273 0.038
positive regulation of cell communication GO:0010647 271 0.038
cellular response to endogenous stimulus GO:0071495 377 0.038
negative regulation of macromolecule metabolic process GO:0010605 260 0.038
cellular amino acid metabolic process GO:0006520 107 0.037
regulation of cell migration GO:0030334 128 0.037
regulation of nucleic acid templated transcription GO:1903506 380 0.037
cellular response to stress GO:0033554 269 0.037
regulation of nervous system development GO:0051960 264 0.036
macromolecule localization GO:0033036 252 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.036
positive regulation of cell motility GO:2000147 97 0.036
purine ribonucleoside catabolic process GO:0046130 124 0.036
growth GO:0040007 165 0.036
cellular catabolic process GO:0044248 295 0.036
response to organophosphorus GO:0046683 102 0.035
lipid metabolic process GO:0006629 283 0.035
ras protein signal transduction GO:0007265 29 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.035
negative regulation of metabolic process GO:0009892 331 0.035
regulation of secretion by cell GO:1903530 208 0.035
regulation of cell development GO:0060284 263 0.035
organic cyclic compound catabolic process GO:1901361 175 0.034
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.034
guanosine containing compound catabolic process GO:1901069 71 0.034
divalent inorganic cation homeostasis GO:0072507 165 0.034
reproduction GO:0000003 245 0.033
nucleobase containing compound catabolic process GO:0034655 152 0.033
amine metabolic process GO:0009308 38 0.033
regulation of cell projection organization GO:0031344 175 0.033
organophosphate catabolic process GO:0046434 148 0.033
purine ribonucleotide catabolic process GO:0009154 136 0.033
nucleoside catabolic process GO:0009164 126 0.033
purine nucleoside triphosphate catabolic process GO:0009146 122 0.032
nucleotide catabolic process GO:0009166 139 0.032
cellular nitrogen compound catabolic process GO:0044270 163 0.032
regulation of neuron differentiation GO:0045664 208 0.032
cgmp biosynthetic process GO:0006182 15 0.032
protein phosphorylation GO:0006468 345 0.031
response to peptide hormone GO:0043434 278 0.031
developmental growth GO:0048589 100 0.031
positive regulation of neurogenesis GO:0050769 165 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
guanosine containing compound metabolic process GO:1901068 74 0.031
transmission of nerve impulse GO:0019226 42 0.030
ribonucleoside catabolic process GO:0042454 126 0.030
positive regulation of neuron projection development GO:0010976 99 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
g protein coupled receptor signaling pathway GO:0007186 242 0.030
cell migration GO:0016477 197 0.030
cellular response to nitrogen compound GO:1901699 210 0.029
negative regulation of transcription dna templated GO:0045892 116 0.029
single organism carbohydrate metabolic process GO:0044723 118 0.029
cellular component morphogenesis GO:0032989 155 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.029
positive regulation of cellular component organization GO:0051130 200 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
positive regulation of catalytic activity GO:0043085 184 0.029
regulation of cell motility GO:2000145 131 0.028
multi organism reproductive process GO:0044703 262 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
nucleoside triphosphate metabolic process GO:0009141 144 0.028
carbohydrate metabolic process GO:0005975 130 0.028
tissue development GO:0009888 252 0.028
positive regulation of locomotion GO:0040017 102 0.028
cellular response to organic cyclic compound GO:0071407 202 0.028
response to interleukin 15 GO:0070672 4 0.028
regulation of gtpase activity GO:0043087 57 0.028
neurological system process GO:0050877 219 0.027
regulation of cellular localization GO:0060341 263 0.027
regulation of nucleotide metabolic process GO:0006140 117 0.027
positive regulation of catabolic process GO:0009896 78 0.027
single organism organelle organization GO:1902589 180 0.026
positive regulation of amine transport GO:0051954 26 0.026
adult locomotory behavior GO:0008344 4 0.026
brain development GO:0007420 247 0.026
positive regulation of neuron differentiation GO:0045666 126 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
positive regulation of molecular function GO:0044093 230 0.026
chemical homeostasis GO:0048878 292 0.026
small molecule biosynthetic process GO:0044283 124 0.025
purine nucleoside catabolic process GO:0006152 124 0.025
neuronal action potential GO:0019228 35 0.025
ribonucleoside triphosphate catabolic process GO:0009203 122 0.025
insulin like growth factor receptor signaling pathway GO:0048009 3 0.025
regulation of apoptotic process GO:0042981 335 0.025
cellular amine metabolic process GO:0044106 38 0.025
organic acid metabolic process GO:0006082 292 0.025
cellular component assembly GO:0022607 360 0.024
cell morphogenesis involved in differentiation GO:0000904 119 0.024
positive regulation of response to stimulus GO:0048584 285 0.023
negative regulation of neuron projection development GO:0010977 46 0.023
regulation of cellular catabolic process GO:0031329 101 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
cellular ketone metabolic process GO:0042180 51 0.023
neuron development GO:0048666 286 0.023
regulation of hydrolase activity GO:0051336 143 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.023
metal ion transport GO:0030001 289 0.023
single organism biosynthetic process GO:0044711 342 0.023
positive regulation of hydrolase activity GO:0051345 86 0.023
dendrite morphogenesis GO:0048813 43 0.022
axon ensheathment GO:0008366 40 0.022
regulation of proteasomal protein catabolic process GO:0061136 4 0.022
response to growth factor GO:0070848 189 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
response to acid chemical GO:0001101 222 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
regulation of protein modification process GO:0031399 194 0.022
response to aluminum ion GO:0010044 10 0.022
regulation of cell proliferation GO:0042127 359 0.022
sensory perception GO:0007600 101 0.022
cellular component movement GO:0006928 248 0.022
gtp metabolic process GO:0046039 72 0.021
response to camp GO:0051591 91 0.021
cell motility GO:0048870 202 0.021
response to cgmp GO:0070305 3 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
locomotion GO:0040011 237 0.021
cellular response to cytokine stimulus GO:0071345 127 0.021
regulation of cell differentiation GO:0045595 320 0.021
regulation of purine nucleotide metabolic process GO:1900542 115 0.021
regulation of dendrite development GO:0050773 59 0.020
regulation of neuron projection development GO:0010975 161 0.020
regulation of kinase activity GO:0043549 117 0.020
regulation of nucleoside metabolic process GO:0009118 66 0.020
response to peptide GO:1901652 292 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
secretion GO:0046903 307 0.020
response to nutrient levels GO:0031667 370 0.020
regulation of protein kinase activity GO:0045859 105 0.020
cell part morphogenesis GO:0032990 123 0.020
protein localization GO:0008104 191 0.020
regulation of cellular component movement GO:0051270 150 0.019
regulation of neurogenesis GO:0050767 247 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
cellular ion homeostasis GO:0006873 184 0.019
protein complex biogenesis GO:0070271 263 0.019
positive regulation of signal transduction GO:0009967 175 0.019
cellular response to cgmp GO:0071321 2 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
negative regulation of gene expression GO:0010629 199 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
negative regulation of cell death GO:0060548 229 0.018
positive regulation of cellular catabolic process GO:0031331 71 0.018
second messenger mediated signaling GO:0019932 51 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
macromolecular complex assembly GO:0065003 273 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
mapk cascade GO:0000165 140 0.018
response to monosaccharide GO:0034284 159 0.018
calcium ion homeostasis GO:0055074 162 0.018
regulation of secretion GO:0051046 224 0.018
positive regulation of nervous system development GO:0051962 178 0.018
regulation of growth GO:0040008 105 0.018
chromosome segregation GO:0007059 2 0.018
regulation of synaptic transmission GO:0050804 141 0.018
regulation of nucleotide catabolic process GO:0030811 65 0.018
positive regulation of gtpase activity GO:0043547 47 0.018
negative regulation of protein metabolic process GO:0051248 114 0.017
carbohydrate biosynthetic process GO:0016051 42 0.017
oxoacid metabolic process GO:0043436 290 0.017
metal ion homeostasis GO:0055065 186 0.017
neuron differentiation GO:0030182 368 0.017
heterocycle catabolic process GO:0046700 167 0.017
protein localization to chromosome centromeric region GO:0071459 1 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
response to reactive oxygen species GO:0000302 120 0.017
regulation of transferase activity GO:0051338 123 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
nitrogen compound transport GO:0071705 229 0.017
multicellular organism reproduction GO:0032504 233 0.017
positive regulation of secretion GO:0051047 140 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
reproductive system development GO:0061458 128 0.017
positive regulation of nucleotide metabolic process GO:0045981 91 0.017
regulation of cell growth GO:0001558 85 0.017
protein transport GO:0015031 132 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
localization of cell GO:0051674 202 0.016
cation homeostasis GO:0055080 195 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
response to alkaloid GO:0043279 132 0.016
apoptotic process GO:0006915 381 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.015
cation transmembrane transport GO:0098655 263 0.015
cell cycle GO:0007049 101 0.015
peroxisome organization GO:0007031 6 0.015
negative regulation of cell communication GO:0010648 158 0.015
cellular chemical homeostasis GO:0055082 247 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
establishment of protein localization GO:0045184 141 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
negative regulation of dendrite development GO:2000171 9 0.015
regulation of gtp catabolic process GO:0033124 58 0.015
single organism cellular localization GO:1902580 102 0.015
protein complex subunit organization GO:0071822 302 0.015
gonad development GO:0008406 104 0.015
response to hydrogen peroxide GO:0042542 89 0.015
regulation of smooth muscle cell migration GO:0014910 36 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
head development GO:0060322 247 0.015
cellular macromolecule localization GO:0070727 122 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
myelination GO:0042552 39 0.014
regulation of signal transduction GO:0009966 318 0.014
positive regulation of protein modification process GO:0031401 142 0.014
positive regulation of tor signaling GO:0032008 2 0.014
positive regulation of nucleotide catabolic process GO:0030813 53 0.014
positive regulation of gtp catabolic process GO:0033126 48 0.014
response to toxic substance GO:0009636 133 0.014
response to increased oxygen levels GO:0036296 45 0.014
positive regulation of organelle organization GO:0010638 48 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
reproductive structure development GO:0048608 128 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
muscle structure development GO:0061061 87 0.013
calcium ion transport GO:0006816 131 0.013
response to extracellular stimulus GO:0009991 380 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
protein complex assembly GO:0006461 263 0.013
sex differentiation GO:0007548 113 0.013
sister chromatid segregation GO:0000819 1 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
cellular protein localization GO:0034613 122 0.013
cellular component biogenesis GO:0044085 368 0.013
homeostatic process GO:0042592 331 0.013
muscle tissue development GO:0060537 58 0.013
regulation of dendrite morphogenesis GO:0048814 33 0.012
regulation of muscle system process GO:0090257 79 0.012
regulation of system process GO:0044057 208 0.012
response to metal ion GO:0010038 253 0.012
alcohol biosynthetic process GO:0046165 38 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
synaptic transmission GO:0007268 235 0.012
regulation of ras gtpase activity GO:0032318 32 0.012
action potential GO:0001508 54 0.012
response to ammonium ion GO:0060359 71 0.012
smooth muscle cell migration GO:0014909 36 0.012
single fertilization GO:0007338 3 0.012
regulation of anatomical structure size GO:0090066 135 0.011
transmembrane transport GO:0055085 412 0.011
regulation of cell size GO:0008361 37 0.011
negative regulation of developmental process GO:0051093 125 0.011
response to carbohydrate GO:0009743 183 0.011
neuron projection morphogenesis GO:0048812 122 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
response to oxygen levels GO:0070482 265 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
regeneration GO:0031099 163 0.011
single organism intracellular transport GO:1902582 166 0.011
peptidyl amino acid modification GO:0018193 126 0.011
cellular cation homeostasis GO:0030003 180 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
salivary gland development GO:0007431 3 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
response to estrogen GO:0043627 232 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
negative regulation of signaling GO:0023057 157 0.011
response to calcium ion GO:0051592 59 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
divalent metal ion transport GO:0070838 132 0.011
positive regulation of transcription factor import into nucleus GO:0042993 4 0.011
epithelial cell differentiation GO:0030855 71 0.011
negative regulation of immune system process GO:0002683 39 0.011
cytoskeleton organization GO:0007010 111 0.011
response to fatty acid GO:0070542 65 0.011
development of primary sexual characteristics GO:0045137 107 0.011
cell cell signaling GO:0007267 335 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
muscle organ development GO:0007517 50 0.010
organic hydroxy compound biosynthetic process GO:1901617 51 0.010
regulation of ion transport GO:0043269 245 0.010
regulation of organelle organization GO:0033043 80 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.010
response to insulin GO:0032868 133 0.010
mitotic sister chromatid segregation GO:0000070 1 0.010

Mpdz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.031
Human
brain disease DOID:936 0 0.031
Human
disease of anatomical entity DOID:7 0 0.031
Human
nervous system disease DOID:863 0 0.031
Human
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
epilepsy syndrome DOID:1826 0 0.015
eye disease DOID:5614 0 0.013
electroclinical syndrome DOID:0050701 0 0.011