Rattus norvegicus

24 known processes

Mt2A

metallothionein 2A

(Aliases: Mt2)

Mt2A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to zinc ion GO:0010043 39 0.576
response to inorganic substance GO:0010035 377 0.320
response to metal ion GO:0010038 253 0.257
response to transition metal nanoparticle GO:1990267 122 0.206
cellular response to external stimulus GO:0071496 118 0.204
cellular response to oxygen containing compound GO:1901701 386 0.135
aging GO:0007568 241 0.114
programmed cell death GO:0012501 392 0.101
response to nutrient levels GO:0031667 370 0.096
regulation of cell proliferation GO:0042127 359 0.082
response to peptide hormone GO:0043434 278 0.076
regulation of protein metabolic process GO:0051246 289 0.073
circulatory system development GO:0072359 134 0.073
intracellular signal transduction GO:0035556 314 0.070
response to biotic stimulus GO:0009607 226 0.070
organic acid metabolic process GO:0006082 292 0.066
response to external biotic stimulus GO:0043207 221 0.064
regulation of apoptotic process GO:0042981 335 0.064
cellular catabolic process GO:0044248 295 0.064
nucleic acid templated transcription GO:0097659 379 0.063
cation transport GO:0006812 382 0.058
response to nutrient GO:0007584 248 0.057
regulation of nucleic acid templated transcription GO:1903506 380 0.052
positive regulation of response to stimulus GO:0048584 285 0.051
epithelium development GO:0060429 96 0.050
tissue development GO:0009888 252 0.049
reproductive process GO:0022414 372 0.049
cofactor metabolic process GO:0051186 95 0.048
negative regulation of cell death GO:0060548 229 0.047
single organism reproductive process GO:0044702 297 0.046
positive regulation of cell communication GO:0010647 271 0.046
regulation of transcription dna templated GO:0006355 374 0.044
regulation of vesicle mediated transport GO:0060627 81 0.044
negative regulation of metabolic process GO:0009892 331 0.042
negative regulation of molecular function GO:0044092 133 0.041
response to estradiol GO:0032355 164 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.039
response to alkaloid GO:0043279 132 0.039
response to molecule of bacterial origin GO:0002237 194 0.039
nitrogen compound transport GO:0071705 229 0.038
cellular response to stress GO:0033554 269 0.037
rna biosynthetic process GO:0032774 380 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
cardiovascular system development GO:0072358 134 0.036
proteolysis GO:0006508 175 0.036
metal ion transport GO:0030001 289 0.036
cellular amino acid metabolic process GO:0006520 107 0.035
regulation of cellular component organization GO:0051128 368 0.035
protein complex biogenesis GO:0070271 263 0.035
negative regulation of multicellular organismal process GO:0051241 203 0.035
oxoacid metabolic process GO:0043436 290 0.035
regulation of intracellular signal transduction GO:1902531 218 0.034
regulation of cell differentiation GO:0045595 320 0.034
circulatory system process GO:0003013 183 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
porphyrin containing compound metabolic process GO:0006778 8 0.033
regulation of rna biosynthetic process GO:2001141 381 0.033
rna metabolic process GO:0016070 406 0.032
tetrapyrrole metabolic process GO:0033013 11 0.031
regulation of neurogenesis GO:0050767 247 0.031
response to extracellular stimulus GO:0009991 380 0.031
response to estrogen GO:0043627 232 0.031
multi multicellular organism process GO:0044706 138 0.031
response to peptide GO:1901652 292 0.031
immune system process GO:0002376 204 0.030
signal transduction by phosphorylation GO:0023014 144 0.029
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.029
response to hydrogen peroxide GO:0042542 89 0.029
positive regulation of signaling GO:0023056 270 0.029
multi organism reproductive process GO:0044703 262 0.029
organic substance catabolic process GO:1901575 316 0.029
chemical homeostasis GO:0048878 292 0.028
transcription dna templated GO:0006351 377 0.028
secretion GO:0046903 307 0.028
neuron differentiation GO:0030182 368 0.028
anatomical structure morphogenesis GO:0009653 298 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.027
cellular component biogenesis GO:0044085 368 0.027
regulation of multicellular organismal development GO:2000026 376 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
positive regulation of developmental process GO:0051094 283 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.027
regulation of programmed cell death GO:0043067 341 0.027
cellular response to growth factor stimulus GO:0071363 162 0.026
organonitrogen compound biosynthetic process GO:1901566 167 0.026
positive regulation of molecular function GO:0044093 230 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
protein complex subunit organization GO:0071822 302 0.026
cellular amine metabolic process GO:0044106 38 0.026
mapk cascade GO:0000165 140 0.026
single organism intracellular transport GO:1902582 166 0.026
regulation of molecular function GO:0065009 398 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
protein oligomerization GO:0051259 191 0.024
positive regulation of neurogenesis GO:0050769 165 0.024
central nervous system development GO:0007417 311 0.024
regulation of cellular localization GO:0060341 263 0.024
cell projection organization GO:0030030 302 0.024
cellular ketone metabolic process GO:0042180 51 0.024
apoptotic process GO:0006915 381 0.024
response to glucocorticoid GO:0051384 223 0.023
cellular component assembly GO:0022607 360 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
homeostatic process GO:0042592 331 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
carbohydrate metabolic process GO:0005975 130 0.023
head development GO:0060322 247 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
response to oxidative stress GO:0006979 186 0.022
cellular response to nutrient levels GO:0031669 60 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
catabolic process GO:0009056 351 0.022
response to other organism GO:0051707 220 0.022
response to cytokine GO:0034097 215 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
amine metabolic process GO:0009308 38 0.022
response to decreased oxygen levels GO:0036293 237 0.022
regulation of neuron differentiation GO:0045664 208 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
response to monosaccharide GO:0034284 159 0.021
cellular homeostasis GO:0019725 252 0.021
response to reactive oxygen species GO:0000302 120 0.021
regulation of immune system process GO:0002682 123 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
anion transport GO:0006820 178 0.021
positive regulation of signal transduction GO:0009967 175 0.021
response to oxygen levels GO:0070482 265 0.020
regulation of secretion GO:0051046 224 0.020
protein localization GO:0008104 191 0.020
regulation of nervous system development GO:0051960 264 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
ion transmembrane transport GO:0034220 365 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
response to lipopolysaccharide GO:0032496 191 0.020
negative regulation of transport GO:0051051 136 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
macromolecule localization GO:0033036 252 0.020
response to hypoxia GO:0001666 231 0.020
reproductive structure development GO:0048608 128 0.020
response to mechanical stimulus GO:0009612 134 0.020
cellular response to abiotic stimulus GO:0071214 85 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.020
multicellular organismal reproductive process GO:0048609 233 0.019
regulation of phosphorylation GO:0042325 248 0.019
cellular response to insulin stimulus GO:0032869 81 0.019
response to corticosteroid GO:0031960 235 0.019
brain development GO:0007420 247 0.019
vesicle mediated transport GO:0016192 181 0.019
regulation of cell projection organization GO:0031344 175 0.019
multicellular organism reproduction GO:0032504 233 0.019
positive regulation of transport GO:0051050 245 0.019
response to acid chemical GO:0001101 222 0.019
cellular response to interleukin 1 GO:0071347 37 0.019
response to growth factor GO:0070848 189 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
intracellular transport GO:0046907 185 0.019
response to bacterium GO:0009617 200 0.019
positive regulation of cell proliferation GO:0008284 249 0.018
endocytosis GO:0006897 84 0.018
single organism biosynthetic process GO:0044711 342 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
sex differentiation GO:0007548 113 0.018
secretion by cell GO:0032940 248 0.018
positive regulation of rna metabolic process GO:0051254 203 0.017
cellular response to mechanical stimulus GO:0071260 48 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
transmembrane transport GO:0055085 412 0.017
vasculature development GO:0001944 70 0.017
macromolecular complex assembly GO:0065003 273 0.017
regulation of signal transduction GO:0009966 318 0.017
protein complex assembly GO:0006461 263 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
cellular component movement GO:0006928 248 0.017
alpha amino acid metabolic process GO:1901605 71 0.017
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.016
organelle organization GO:0006996 266 0.016
immune response GO:0006955 104 0.016
sexual reproduction GO:0019953 148 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
response to hexose GO:0009746 144 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
response to interleukin 1 GO:0070555 55 0.016
positive regulation of gene expression GO:0010628 244 0.016
neuron development GO:0048666 286 0.016
nucleotide metabolic process GO:0009117 279 0.016
monosaccharide metabolic process GO:0005996 61 0.016
response to ketone GO:1901654 182 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
regulation of rna metabolic process GO:0051252 391 0.015
regulation of catalytic activity GO:0050790 304 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
gamete generation GO:0007276 124 0.015
cellular response to extracellular stimulus GO:0031668 73 0.015
cell cell signaling GO:0007267 335 0.015
response to carbohydrate GO:0009743 183 0.015
development of primary sexual characteristics GO:0045137 107 0.015
regulation of smooth muscle cell proliferation GO:0048660 75 0.015
regulation of vasculature development GO:1901342 44 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
regulation of cell development GO:0060284 263 0.015
regulation of neuron projection development GO:0010975 161 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
regulation of system process GO:0044057 208 0.015
cellular chemical homeostasis GO:0055082 247 0.014
regulation of body fluid levels GO:0050878 90 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
reproduction GO:0000003 245 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
carbohydrate homeostasis GO:0033500 75 0.014
intracellular protein transport GO:0006886 79 0.014
amide transport GO:0042886 105 0.014
metal ion homeostasis GO:0055065 186 0.014
regulation of secretion by cell GO:1903530 208 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
response to ethanol GO:0045471 162 0.014
cellular cation homeostasis GO:0030003 180 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
inflammatory response GO:0006954 150 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
amide biosynthetic process GO:0043604 10 0.013
single organism catabolic process GO:0044712 283 0.013
gonad development GO:0008406 104 0.013
autophagic cell death GO:0048102 4 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
epithelial cell differentiation GO:0030855 71 0.013
response to insulin GO:0032868 133 0.013
gland development GO:0048732 155 0.013
positive regulation of nervous system development GO:0051962 178 0.013
defense response GO:0006952 194 0.013
female pregnancy GO:0007565 122 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
synaptic transmission GO:0007268 235 0.013
hexose metabolic process GO:0019318 58 0.013
branched chain amino acid transport GO:0015803 2 0.013
cellular response to biotic stimulus GO:0071216 59 0.013
ras protein signal transduction GO:0007265 29 0.013
ion homeostasis GO:0050801 212 0.012
regulation of protein modification process GO:0031399 194 0.012
regulation of hormone levels GO:0010817 187 0.012
cellular protein localization GO:0034613 122 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
growth GO:0040007 165 0.012
neuron death GO:0070997 127 0.012
carboxylic acid transport GO:0046942 115 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
urogenital system development GO:0001655 78 0.012
cellular response to molecule of bacterial origin GO:0071219 56 0.012
regulation of cellular component movement GO:0051270 150 0.012
response to purine containing compound GO:0014074 126 0.012
oxidation reduction process GO:0055114 304 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of hydrolase activity GO:0051336 143 0.012
peptide biosynthetic process GO:0043043 3 0.011
maternal process involved in female pregnancy GO:0060135 38 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
regulation of peptide transport GO:0090087 87 0.011
tube development GO:0035295 89 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
regulation of neuron death GO:1901214 115 0.011
positive regulation of immune system process GO:0002684 90 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
cellular response to lipid GO:0071396 201 0.011
cellular response to lipopolysaccharide GO:0071222 55 0.011
negative regulation of gene expression GO:0010629 199 0.011
response to magnesium ion GO:0032026 20 0.011
protein phosphorylation GO:0006468 345 0.011
response to glucose GO:0009749 136 0.011
cation homeostasis GO:0055080 195 0.011
cellular ion homeostasis GO:0006873 184 0.011
organic anion transport GO:0015711 132 0.011
protein maturation GO:0051604 68 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
mesenchymal cell proliferation GO:0010463 4 0.011
positive regulation of cell development GO:0010720 176 0.010
coenzyme metabolic process GO:0006732 86 0.010
cellular amino acid biosynthetic process GO:0008652 32 0.010
organic hydroxy compound transport GO:0015850 77 0.010
cell type specific apoptotic process GO:0097285 134 0.010
axis specification GO:0009798 4 0.010
localization of cell GO:0051674 202 0.010
regulation of proteolysis GO:0030162 66 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
neuron projection development GO:0031175 273 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
cellular response to oxidative stress GO:0034599 76 0.010
muscle cell proliferation GO:0033002 84 0.010
calcium ion homeostasis GO:0055074 162 0.010
defense response to gram negative bacterium GO:0050829 3 0.010

Mt2A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
epilepsy syndrome DOID:1826 0 0.029
central nervous system disease DOID:331 0 0.029
brain disease DOID:936 0 0.029
disease of metabolism DOID:0014667 0 0.015
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012