Rattus norvegicus

14 known processes

Mtdh

metadherin

(Aliases: Lyric)

Mtdh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.110
transcription dna templated GO:0006351 377 0.088
regulation of rna biosynthetic process GO:2001141 381 0.087
regulation of nucleic acid templated transcription GO:1903506 380 0.086
regulation of rna metabolic process GO:0051252 391 0.080
nucleic acid templated transcription GO:0097659 379 0.066
rna biosynthetic process GO:0032774 380 0.065
cell projection organization GO:0030030 302 0.056
regulation of transcription dna templated GO:0006355 374 0.053
cellular component morphogenesis GO:0032989 155 0.052
cell cell signaling GO:0007267 335 0.048
response to cytokine GO:0034097 215 0.047
synaptic transmission GO:0007268 235 0.047
transcription from rna polymerase ii promoter GO:0006366 252 0.044
regulation of programmed cell death GO:0043067 341 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
anatomical structure morphogenesis GO:0009653 298 0.043
positive regulation of gene expression GO:0010628 244 0.042
macromolecular complex subunit organization GO:0043933 339 0.042
negative regulation of metabolic process GO:0009892 331 0.042
regulation of apoptotic process GO:0042981 335 0.041
carbohydrate metabolic process GO:0005975 130 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.039
regulation of cell projection organization GO:0031344 175 0.039
cellular component assembly GO:0022607 360 0.039
protein phosphorylation GO:0006468 345 0.039
regulation of proteasomal protein catabolic process GO:0061136 4 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
secretion GO:0046903 307 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.036
positive regulation of cellular component organization GO:0051130 200 0.036
negative regulation of biosynthetic process GO:0009890 168 0.036
response to molecule of bacterial origin GO:0002237 194 0.035
organelle organization GO:0006996 266 0.035
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.034
positive regulation of biosynthetic process GO:0009891 319 0.033
programmed cell death GO:0012501 392 0.033
apoptotic process GO:0006915 381 0.033
reproduction GO:0000003 245 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.033
single organism reproductive process GO:0044702 297 0.031
response to inorganic substance GO:0010035 377 0.031
metal ion transport GO:0030001 289 0.031
regulation of neuron differentiation GO:0045664 208 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.030
cellular response to stress GO:0033554 269 0.030
intracellular signal transduction GO:0035556 314 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
cell projection morphogenesis GO:0048858 123 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.029
positive regulation of transport GO:0051050 245 0.029
vesicle mediated transport GO:0016192 181 0.029
oxidation reduction process GO:0055114 304 0.029
synaptic growth at neuromuscular junction GO:0051124 1 0.029
cell part morphogenesis GO:0032990 123 0.029
negative regulation of cell communication GO:0010648 158 0.029
enzyme linked receptor protein signaling pathway GO:0007167 116 0.029
locomotion GO:0040011 237 0.029
regulation of phosphate metabolic process GO:0019220 349 0.028
embryonic pattern specification GO:0009880 1 0.028
regulation of neurogenesis GO:0050767 247 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.028
behavior GO:0007610 205 0.028
neuron projection development GO:0031175 273 0.028
regulation of cell differentiation GO:0045595 320 0.028
homeostatic process GO:0042592 331 0.028
chromosome segregation GO:0007059 2 0.028
reproductive process GO:0022414 372 0.027
cellular homeostasis GO:0019725 252 0.027
positive regulation of neurogenesis GO:0050769 165 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
regulation of signal transduction GO:0009966 318 0.027
regulation of system process GO:0044057 208 0.026
negative regulation of cell death GO:0060548 229 0.026
gastrulation GO:0007369 2 0.026
protein complex subunit organization GO:0071822 302 0.026
positive regulation of cell development GO:0010720 176 0.026
neuron differentiation GO:0030182 368 0.026
regulation of nervous system development GO:0051960 264 0.026
positive regulation of signaling GO:0023056 270 0.026
cellular component biogenesis GO:0044085 368 0.025
aging GO:0007568 241 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
cell migration GO:0016477 197 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
multicellular organism reproduction GO:0032504 233 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
cellular amine metabolic process GO:0044106 38 0.025
anterior posterior pattern specification GO:0009952 1 0.024
cellular chemical homeostasis GO:0055082 247 0.024
response to metal ion GO:0010038 253 0.024
cellular response to organonitrogen compound GO:0071417 197 0.024
cell morphogenesis involved in differentiation GO:0000904 119 0.024
amine metabolic process GO:0009308 38 0.024
single organism carbohydrate metabolic process GO:0044723 118 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
negative regulation of signaling GO:0023057 157 0.024
neurological system process GO:0050877 219 0.024
regulation of protein metabolic process GO:0051246 289 0.024
response to estrogen GO:0043627 232 0.024
multi organism reproductive process GO:0044703 262 0.024
regulation of cellular component organization GO:0051128 368 0.024
regulation of cell development GO:0060284 263 0.024
cation transport GO:0006812 382 0.024
positive regulation of signal transduction GO:0009967 175 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
negative regulation of gene expression GO:0010629 199 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
positive regulation of cell death GO:0010942 184 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
blood circulation GO:0008015 183 0.023
regulation of neuron projection development GO:0010975 161 0.023
muscle system process GO:0003012 115 0.023
neuron death GO:0070997 127 0.023
signal release GO:0023061 145 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
cellular response to cytokine stimulus GO:0071345 127 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
response to growth factor GO:0070848 189 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
head development GO:0060322 247 0.022
cellular response to peptide GO:1901653 133 0.021
chemical homeostasis GO:0048878 292 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
brain development GO:0007420 247 0.021
mesoderm development GO:0007498 2 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
single organism intracellular transport GO:1902582 166 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
regulation of cellular localization GO:0060341 263 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
cellular cation homeostasis GO:0030003 180 0.020
response to nutrient GO:0007584 248 0.020
response to extracellular stimulus GO:0009991 380 0.020
regulation of molecular function GO:0065009 398 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
regulation of protein modification process GO:0031399 194 0.020
regulation of phosphorylation GO:0042325 248 0.020
ion transmembrane transport GO:0034220 365 0.020
cellular ketone metabolic process GO:0042180 51 0.020
response to biotic stimulus GO:0009607 226 0.020
single organism membrane organization GO:0044802 74 0.020
positive regulation of molecular function GO:0044093 230 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
cell cycle GO:0007049 101 0.020
single organism organelle organization GO:1902589 180 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
response to nutrient levels GO:0031667 370 0.020
ion homeostasis GO:0050801 212 0.020
regulation of catalytic activity GO:0050790 304 0.020
response to lipopolysaccharide GO:0032496 191 0.020
response to mechanical stimulus GO:0009612 134 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
cognition GO:0050890 92 0.019
macromolecular complex assembly GO:0065003 273 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
oxoacid metabolic process GO:0043436 290 0.019
response to carbohydrate GO:0009743 183 0.019
regulation of cell morphogenesis GO:0022604 77 0.019
actin filament based process GO:0030029 86 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
spindle organization GO:0007051 2 0.019
cellular catabolic process GO:0044248 295 0.019
dendrite development GO:0016358 72 0.019
cellular component movement GO:0006928 248 0.019
regulation of synaptic transmission GO:0050804 141 0.019
regulation of secretion GO:0051046 224 0.018
protein complex assembly GO:0006461 263 0.018
protein complex biogenesis GO:0070271 263 0.018
cell motility GO:0048870 202 0.018
regulation of chromosome segregation GO:0051983 1 0.018
intracellular transport GO:0046907 185 0.018
organic acid metabolic process GO:0006082 292 0.018
response to peptide hormone GO:0043434 278 0.018
positive regulation of nervous system development GO:0051962 178 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
macromolecule localization GO:0033036 252 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
anion transport GO:0006820 178 0.018
cellular ion homeostasis GO:0006873 184 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
tissue development GO:0009888 252 0.017
membrane organization GO:0061024 94 0.017
single organism biosynthetic process GO:0044711 342 0.017
somatic stem cell maintenance GO:0035019 2 0.017
regulation of mapk cascade GO:0043408 116 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
regulation of synaptic plasticity GO:0048167 70 0.017
organophosphate metabolic process GO:0019637 370 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
growth GO:0040007 165 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
cytoplasmic transport GO:0016482 115 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.016
catabolic process GO:0009056 351 0.016
axis specification GO:0009798 4 0.016
localization of cell GO:0051674 202 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
regulation of secretion by cell GO:1903530 208 0.016
gliogenesis GO:0042063 93 0.016
protein localization GO:0008104 191 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
positive regulation of developmental process GO:0051094 283 0.016
regulation of hormone levels GO:0010817 187 0.016
organic acid transport GO:0015849 116 0.016
neuron apoptotic process GO:0051402 88 0.016
regulation of kinase activity GO:0043549 117 0.016
secretion by cell GO:0032940 248 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
central nervous system development GO:0007417 311 0.015
lipid metabolic process GO:0006629 283 0.015
peptidyl amino acid modification GO:0018193 126 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
cellular response to external stimulus GO:0071496 118 0.015
sexual reproduction GO:0019953 148 0.015
response to ethanol GO:0045471 162 0.015
response to radiation GO:0009314 137 0.015
metaphase anaphase transition of cell cycle GO:0044784 1 0.015
hexose metabolic process GO:0019318 58 0.015
nucleotide metabolic process GO:0009117 279 0.015
regulation of neurotransmitter levels GO:0001505 42 0.015
immune system process GO:0002376 204 0.015
neuron projection morphogenesis GO:0048812 122 0.014
negative regulation of transport GO:0051051 136 0.014
circulatory system development GO:0072359 134 0.014
dendrite morphogenesis GO:0048813 43 0.014
single organism behavior GO:0044708 130 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
heart morphogenesis GO:0003007 3 0.014
metal ion homeostasis GO:0055065 186 0.014
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
regulation of membrane potential GO:0042391 110 0.014
chemosensory behavior GO:0007635 2 0.014
response to peptide GO:1901652 292 0.014
olfactory learning GO:0008355 1 0.014
sex differentiation GO:0007548 113 0.014
regulation of locomotion GO:0040012 148 0.014
regulation of dna metabolic process GO:0051052 60 0.014
response to oxygen levels GO:0070482 265 0.013
positive regulation of cell communication GO:0010647 271 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
calcium ion homeostasis GO:0055074 162 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.013
response to monosaccharide GO:0034284 159 0.013
response to tumor necrosis factor GO:0034612 56 0.013
rhythmic process GO:0048511 156 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.013
nitrogen compound transport GO:0071705 229 0.013
developmental growth GO:0048589 100 0.013
positive regulation of mitochondrion organization GO:0010822 4 0.013
regulation of sister chromatid segregation GO:0033045 1 0.013
salivary gland development GO:0007431 3 0.013
single organism catabolic process GO:0044712 283 0.013
mitotic sister chromatid separation GO:0051306 1 0.013
actin cytoskeleton organization GO:0030036 73 0.013
neuron development GO:0048666 286 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.013
development of primary sexual characteristics GO:0045137 107 0.013
response to hexose GO:0009746 144 0.013
regulation of response to stress GO:0080134 126 0.013
negative regulation of cell development GO:0010721 82 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
proteolysis GO:0006508 175 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
regulation of mitotic sister chromatid segregation GO:0033047 1 0.013
cardiovascular system development GO:0072358 134 0.013
multicellular organism growth GO:0035264 1 0.013
carboxylic acid metabolic process GO:0019752 289 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
response to glucocorticoid GO:0051384 223 0.013
cation homeostasis GO:0055080 195 0.013
developmental process involved in reproduction GO:0003006 159 0.013
cytoskeleton organization GO:0007010 111 0.013
cellular lipid metabolic process GO:0044255 208 0.013
cell morphogenesis GO:0000902 142 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
regulation of dendrite development GO:0050773 59 0.012
transmembrane transport GO:0055085 412 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
negative regulation of signal transduction GO:0009968 83 0.012
olfactory behavior GO:0042048 2 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
monosaccharide metabolic process GO:0005996 61 0.012
muscle structure development GO:0061061 87 0.012
synapse organization GO:0050808 46 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
circulatory system process GO:0003013 183 0.012
protein oligomerization GO:0051259 191 0.012
hormone transport GO:0009914 121 0.012
response to bacterium GO:0009617 200 0.012
purine containing compound metabolic process GO:0072521 253 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
meiotic cell cycle process GO:1903046 3 0.012
heart development GO:0007507 72 0.012
defense response GO:0006952 194 0.012
response to decreased oxygen levels GO:0036293 237 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
formation of primary germ layer GO:0001704 1 0.012
calcium ion transport GO:0006816 131 0.012
positive regulation of protein modification process GO:0031401 142 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
circadian rhythm GO:0007623 88 0.012
glucose metabolic process GO:0006006 52 0.012
divalent inorganic cation transport GO:0072511 134 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
epithelium development GO:0060429 96 0.012
reproductive structure development GO:0048608 128 0.012
spermatogenesis GO:0007283 99 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
biological adhesion GO:0022610 110 0.011
regulation of mitotic sister chromatid separation GO:0010965 1 0.011
regulation of ion transport GO:0043269 245 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.011
bmp signaling pathway GO:0030509 4 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
protein autophosphorylation GO:0046777 66 0.011
response to toxic substance GO:0009636 133 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.011
response to alkaloid GO:0043279 132 0.011
embryonic axis specification GO:0000578 1 0.011
negative regulation of nervous system development GO:0051961 79 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
response to glucose GO:0009749 136 0.011
heterocycle catabolic process GO:0046700 167 0.011
gamete generation GO:0007276 124 0.011
response to insulin GO:0032868 133 0.011
chromosome separation GO:0051304 1 0.011
maintenance of location GO:0051235 17 0.011
regulation of neuron death GO:1901214 115 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
amide transport GO:0042886 105 0.011
response to estradiol GO:0032355 164 0.011
cellular response to lipid GO:0071396 201 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
regulation of stem cell differentiation GO:2000736 2 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
rna localization GO:0006403 4 0.010
positive regulation of synapse maturation GO:0090129 2 0.010
negative regulation of innate immune response GO:0045824 4 0.010
dna metabolic process GO:0006259 96 0.010
divalent metal ion transport GO:0070838 132 0.010
ras protein signal transduction GO:0007265 29 0.010
regulation of notch signaling pathway GO:0008593 3 0.010
anion transmembrane transport GO:0098656 77 0.010
response to acid chemical GO:0001101 222 0.010
negative regulation of organ growth GO:0046621 3 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
microtubule organizing center organization GO:0031023 1 0.010
muscle contraction GO:0006936 88 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
regulation of organelle organization GO:0033043 80 0.010
mapk cascade GO:0000165 140 0.010
sensory perception GO:0007600 101 0.010
regulation of cell motility GO:2000145 131 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
cell adhesion GO:0007155 110 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
regulation of cell migration GO:0030334 128 0.010

Mtdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
musculoskeletal system disease DOID:17 0 0.015
cardiovascular system disease DOID:1287 0 0.014
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013