Rattus norvegicus

71 known processes

Mvk

mevalonate kinase

Mvk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid biosynthetic process GO:0008610 128 0.150
cellular lipid metabolic process GO:0044255 208 0.149
lipid metabolic process GO:0006629 283 0.148
small molecule biosynthetic process GO:0044283 124 0.147
single organism biosynthetic process GO:0044711 342 0.116
organic hydroxy compound metabolic process GO:1901615 115 0.090
organophosphate metabolic process GO:0019637 370 0.084
positive regulation of biosynthetic process GO:0009891 319 0.074
isoprenoid metabolic process GO:0006720 45 0.072
phospholipid metabolic process GO:0006644 61 0.066
inorganic ion transmembrane transport GO:0098660 229 0.065
alcohol metabolic process GO:0006066 77 0.060
single organism reproductive process GO:0044702 297 0.057
regulation of molecular function GO:0065009 398 0.056
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.053
positive regulation of developmental process GO:0051094 283 0.048
organic acid biosynthetic process GO:0016053 83 0.046
regulation of nervous system development GO:0051960 264 0.046
organic acid metabolic process GO:0006082 292 0.044
regulation of cell proliferation GO:0042127 359 0.044
amine metabolic process GO:0009308 38 0.042
cell projection organization GO:0030030 302 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.040
tissue development GO:0009888 252 0.040
cellular amine metabolic process GO:0044106 38 0.040
neuron development GO:0048666 286 0.040
cofactor metabolic process GO:0051186 95 0.040
regulation of cellular amine metabolic process GO:0033238 8 0.039
neuron differentiation GO:0030182 368 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.038
cell cell signaling GO:0007267 335 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
oxoacid metabolic process GO:0043436 290 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.038
response to peptide GO:1901652 292 0.037
cellular response to lipid GO:0071396 201 0.036
reproductive process GO:0022414 372 0.035
steroid biosynthetic process GO:0006694 48 0.035
coenzyme metabolic process GO:0006732 86 0.035
multicellular organismal reproductive process GO:0048609 233 0.034
carboxylic acid biosynthetic process GO:0046394 83 0.034
regulation of multicellular organismal development GO:2000026 376 0.033
negative regulation of metabolic process GO:0009892 331 0.033
regulation of phosphate metabolic process GO:0019220 349 0.033
transmembrane transport GO:0055085 412 0.033
response to ethanol GO:0045471 162 0.033
regulation of neuron differentiation GO:0045664 208 0.033
macromolecule localization GO:0033036 252 0.032
synaptic transmission GO:0007268 235 0.032
anatomical structure morphogenesis GO:0009653 298 0.032
central nervous system development GO:0007417 311 0.032
cellular amino acid metabolic process GO:0006520 107 0.031
regulation of rna biosynthetic process GO:2001141 381 0.031
organophosphate biosynthetic process GO:0090407 143 0.031
neurological system process GO:0050877 219 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
rna biosynthetic process GO:0032774 380 0.030
regulation of cell development GO:0060284 263 0.030
response to nutrient GO:0007584 248 0.029
response to nutrient levels GO:0031667 370 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
transcription dna templated GO:0006351 377 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
cellular ketone metabolic process GO:0042180 51 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
cholesterol metabolic process GO:0008203 17 0.028
regulation of catalytic activity GO:0050790 304 0.028
regulation of membrane potential GO:0042391 110 0.028
programmed cell death GO:0012501 392 0.028
sterol metabolic process GO:0016125 18 0.028
regulation of cell differentiation GO:0045595 320 0.028
developmental process involved in reproduction GO:0003006 159 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
ion transmembrane transport GO:0034220 365 0.027
anion transport GO:0006820 178 0.027
cation transport GO:0006812 382 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
positive regulation of cell development GO:0010720 176 0.026
regulation of neurogenesis GO:0050767 247 0.026
regulation of transcription dna templated GO:0006355 374 0.026
phospholipid biosynthetic process GO:0008654 29 0.026
tube development GO:0035295 89 0.026
multicellular organism reproduction GO:0032504 233 0.025
intracellular signal transduction GO:0035556 314 0.025
neuron projection development GO:0031175 273 0.025
regulation of lipid biosynthetic process GO:0046890 38 0.025
brain development GO:0007420 247 0.025
response to extracellular stimulus GO:0009991 380 0.025
catabolic process GO:0009056 351 0.025
regulation of lipid metabolic process GO:0019216 68 0.024
organic substance catabolic process GO:1901575 316 0.024
positive regulation of signaling GO:0023056 270 0.024
single organism catabolic process GO:0044712 283 0.024
acyl coa metabolic process GO:0006637 28 0.024
intracellular transport GO:0046907 185 0.024
gamete generation GO:0007276 124 0.024
response to corticosteroid GO:0031960 235 0.024
carboxylic acid metabolic process GO:0019752 289 0.024
response to peptide hormone GO:0043434 278 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
aging GO:0007568 241 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
organonitrogen compound biosynthetic process GO:1901566 167 0.023
homeostatic process GO:0042592 331 0.023
head development GO:0060322 247 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
negative regulation of transcription dna templated GO:0045892 116 0.023
regulation of cellular component organization GO:0051128 368 0.023
positive regulation of molecular function GO:0044093 230 0.022
cation transmembrane transport GO:0098655 263 0.022
nucleic acid templated transcription GO:0097659 379 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
negative regulation of rna metabolic process GO:0051253 123 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
membrane organization GO:0061024 94 0.022
cellular response to nitrogen compound GO:1901699 210 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
heart morphogenesis GO:0003007 3 0.021
nucleotide metabolic process GO:0009117 279 0.021
regulation of system process GO:0044057 208 0.021
positive regulation of cell communication GO:0010647 271 0.021
cellular homeostasis GO:0019725 252 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
negative regulation of signaling GO:0023057 157 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
organelle organization GO:0006996 266 0.021
neuronal action potential GO:0019228 35 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
regulation of phosphorylation GO:0042325 248 0.020
monocarboxylic acid biosynthetic process GO:0072330 48 0.020
vesicle mediated transport GO:0016192 181 0.020
response to vitamin GO:0033273 131 0.020
multi organism reproductive process GO:0044703 262 0.020
cell projection morphogenesis GO:0048858 123 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
metal ion transport GO:0030001 289 0.019
secretion GO:0046903 307 0.019
ras protein signal transduction GO:0007265 29 0.019
apoptotic process GO:0006915 381 0.019
response to insulin GO:0032868 133 0.019
axis specification GO:0009798 4 0.019
regulation of apoptotic process GO:0042981 335 0.019
regulation of rna metabolic process GO:0051252 391 0.019
cell part morphogenesis GO:0032990 123 0.019
response to radiation GO:0009314 137 0.018
cellular chemical homeostasis GO:0055082 247 0.018
negative regulation of neuron differentiation GO:0045665 62 0.018
response to glucocorticoid GO:0051384 223 0.018
cholesterol biosynthetic process GO:0006695 10 0.018
action potential GO:0001508 54 0.018
steroid metabolic process GO:0008202 73 0.018
ion homeostasis GO:0050801 212 0.018
cellular component morphogenesis GO:0032989 155 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
positive regulation of nervous system development GO:0051962 178 0.018
negative regulation of molecular function GO:0044092 133 0.018
reproduction GO:0000003 245 0.018
alcohol biosynthetic process GO:0046165 38 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
regulation of secretion GO:0051046 224 0.018
reproductive system development GO:0061458 128 0.018
transmission of nerve impulse GO:0019226 42 0.017
reproductive structure development GO:0048608 128 0.017
axon development GO:0061564 96 0.017
cellular component assembly GO:0022607 360 0.017
regulation of cholesterol metabolic process GO:0090181 5 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
positive regulation of cell death GO:0010942 184 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
negative regulation of gene expression GO:0010629 199 0.017
response to acid chemical GO:0001101 222 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
organic acid transport GO:0015849 116 0.017
negative regulation of neurogenesis GO:0050768 78 0.017
regulation of hormone levels GO:0010817 187 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
organic hydroxy compound biosynthetic process GO:1901617 51 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
cytoskeleton organization GO:0007010 111 0.016
purine containing compound metabolic process GO:0072521 253 0.016
negative regulation of transport GO:0051051 136 0.016
macromolecular complex assembly GO:0065003 273 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
multicellular organismal signaling GO:0035637 44 0.016
sexual reproduction GO:0019953 148 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
response to purine containing compound GO:0014074 126 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
embryonic pattern specification GO:0009880 1 0.016
sensory organ development GO:0007423 74 0.016
protein localization GO:0008104 191 0.016
protein complex subunit organization GO:0071822 302 0.016
regulation of cell projection organization GO:0031344 175 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
spermatogenesis GO:0007283 99 0.016
retina morphogenesis in camera type eye GO:0060042 1 0.015
positive regulation of gene expression GO:0010628 244 0.015
male sex differentiation GO:0046661 64 0.015
cellular component biogenesis GO:0044085 368 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
regulation of growth GO:0040008 105 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
eye morphogenesis GO:0048592 4 0.014
negative regulation of cell development GO:0010721 82 0.014
sex differentiation GO:0007548 113 0.014
negative regulation of developmental process GO:0051093 125 0.014
response to organophosphorus GO:0046683 102 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
protein complex assembly GO:0006461 263 0.014
regulation of signal transduction GO:0009966 318 0.014
negative regulation of cell communication GO:0010648 158 0.014
chemical homeostasis GO:0048878 292 0.014
single organism organelle organization GO:1902589 180 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
organic anion transport GO:0015711 132 0.014
response to camp GO:0051591 91 0.014
forebrain development GO:0030900 98 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
secretion by cell GO:0032940 248 0.014
cellular response to stress GO:0033554 269 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
response to bacterium GO:0009617 200 0.014
response to estrogen GO:0043627 232 0.013
regulation of immune system process GO:0002682 123 0.013
organophosphate catabolic process GO:0046434 148 0.013
anterior posterior pattern specification GO:0009952 1 0.013
cellular catabolic process GO:0044248 295 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
cell cycle GO:0007049 101 0.013
male gamete generation GO:0048232 99 0.013
cellular component movement GO:0006928 248 0.013
proteolysis GO:0006508 175 0.013
regulation of cellular localization GO:0060341 263 0.013
rhythmic process GO:0048511 156 0.013
regulation of programmed cell death GO:0043067 341 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
adult locomotory behavior GO:0008344 4 0.013
cell morphogenesis GO:0000902 142 0.013
carboxylic acid transport GO:0046942 115 0.013
regulation of protein metabolic process GO:0051246 289 0.013
acrosome assembly GO:0001675 3 0.013
cellular cation homeostasis GO:0030003 180 0.013
response to growth factor GO:0070848 189 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
hormone transport GO:0009914 121 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
sterol homeostasis GO:0055092 3 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
response to inorganic substance GO:0010035 377 0.012
neuron projection morphogenesis GO:0048812 122 0.012
response to retinoic acid GO:0032526 63 0.012
signal release GO:0023061 145 0.012
camera type eye morphogenesis GO:0048593 2 0.012
renal system development GO:0072001 67 0.012
protein complex biogenesis GO:0070271 263 0.012
response to monosaccharide GO:0034284 159 0.012
blood circulation GO:0008015 183 0.012
growth GO:0040007 165 0.012
regulation of secretion by cell GO:1903530 208 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
single organism intracellular transport GO:1902582 166 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
intestinal absorption GO:0050892 3 0.012
developmental growth GO:0048589 100 0.012
positive regulation of lipid biosynthetic process GO:0046889 25 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
response to carbohydrate GO:0009743 183 0.012
intracellular receptor signaling pathway GO:0030522 35 0.011
cellular response to alcohol GO:0097306 87 0.011
rna metabolic process GO:0016070 406 0.011
regulation of plasma lipoprotein particle levels GO:0097006 3 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
digestive system development GO:0055123 41 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
nucleoside metabolic process GO:0009116 179 0.011
localization of cell GO:0051674 202 0.011
response to ketone GO:1901654 182 0.011
circulatory system process GO:0003013 183 0.011
regulation of synaptic transmission GO:0050804 141 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
response to estradiol GO:0032355 164 0.011
fatty acid biosynthetic process GO:0006633 33 0.011
circadian rhythm GO:0007623 88 0.011
regulation of transferase activity GO:0051338 123 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
positive regulation of secretion GO:0051047 140 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of intracellular signal transduction GO:1902531 218 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
negative regulation of cell death GO:0060548 229 0.010
rna localization GO:0006403 4 0.010
response to alkaloid GO:0043279 132 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
regulation of kinase activity GO:0043549 117 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
response to hexose GO:0009746 144 0.010
response to toxic substance GO:0009636 133 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
response to fatty acid GO:0070542 65 0.010
regulation of ion transport GO:0043269 245 0.010
cognition GO:0050890 92 0.010
multicellular organism growth GO:0035264 1 0.010
camera type eye development GO:0043010 48 0.010
purine containing compound catabolic process GO:0072523 138 0.010

Mvk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.026
inherited metabolic disorder DOID:655 0 0.026
disease of anatomical entity DOID:7 0 0.020
musculoskeletal system disease DOID:17 0 0.020
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
nervous system disease DOID:863 0 0.010