Rattus norvegicus

7 known processes

Myh2

myosin, heavy chain 2, skeletal muscle, adult

(Aliases: Myh2a,MyHC-2A,Myh1,MyHC-IIA)

Myh2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myosin filament assembly GO:0031034 1 0.345
Mouse
ribonucleotide metabolic process GO:0009259 231 0.272
Rat
regulation of phosphate metabolic process GO:0019220 349 0.189
muscle system process GO:0003012 115 0.189
muscle contraction GO:0006936 88 0.174
myosin filament organization GO:0031033 2 0.166
Mouse
rhythmic process GO:0048511 156 0.163
carbohydrate derivative metabolic process GO:1901135 346 0.159
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.141
Rat
purine containing compound metabolic process GO:0072521 253 0.139
Rat
cardiac muscle contraction GO:0060048 27 0.136
nucleotide metabolic process GO:0009117 279 0.134
Rat
striated muscle contraction GO:0006941 44 0.128
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.122
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.122
Rat
response to biotic stimulus GO:0009607 226 0.118
blood circulation GO:0008015 183 0.116
cation transport GO:0006812 382 0.110
heart process GO:0003015 57 0.106
transmembrane transport GO:0055085 412 0.105
negative regulation of metabolic process GO:0009892 331 0.105
regulation of catalytic activity GO:0050790 304 0.100
purine nucleoside triphosphate catabolic process GO:0009146 122 0.098
Rat
tissue development GO:0009888 252 0.095
Mouse
purine nucleotide metabolic process GO:0006163 229 0.093
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.087
cardiac ventricle development GO:0003231 1 0.087
positive regulation of signaling GO:0023056 270 0.083
purine ribonucleoside catabolic process GO:0046130 124 0.083
Rat
glycosyl compound catabolic process GO:1901658 126 0.081
Rat
circulatory system process GO:0003013 183 0.077
intracellular signal transduction GO:0035556 314 0.075
homeostatic process GO:0042592 331 0.075
organophosphate metabolic process GO:0019637 370 0.074
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.071
Rat
regulation of apoptotic process GO:0042981 335 0.070
response to oxidative stress GO:0006979 186 0.068
Rat
regulation of muscle contraction GO:0006937 53 0.066
negative regulation of macromolecule metabolic process GO:0010605 260 0.066
protein phosphorylation GO:0006468 345 0.065
actin myosin filament sliding GO:0033275 2 0.064
ribose phosphate metabolic process GO:0019693 235 0.062
Rat
muscle tissue development GO:0060537 58 0.061
Mouse
purine nucleotide catabolic process GO:0006195 136 0.061
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.059
cation transmembrane transport GO:0098655 263 0.059
purine nucleoside metabolic process GO:0042278 169 0.058
Rat
heart contraction GO:0060047 57 0.057
nucleoside catabolic process GO:0009164 126 0.053
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.053
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.051
Rat
cytoskeleton organization GO:0007010 111 0.051
Mouse
response to carbohydrate GO:0009743 183 0.051
purine nucleoside triphosphate metabolic process GO:0009144 141 0.051
Rat
neuron development GO:0048666 286 0.050
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.049
Rat
negative regulation of cell death GO:0060548 229 0.049
regulation of molecular function GO:0065009 398 0.049
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.048
organelle organization GO:0006996 266 0.048
Mouse
chemical homeostasis GO:0048878 292 0.048
defense response GO:0006952 194 0.048
growth GO:0040007 165 0.047
cellular response to oxygen containing compound GO:1901701 386 0.047
anatomical structure morphogenesis GO:0009653 298 0.046
Mouse
response to toxic substance GO:0009636 133 0.046
nucleoside triphosphate catabolic process GO:0009143 123 0.046
Rat
regulation of system process GO:0044057 208 0.045
actin mediated cell contraction GO:0070252 12 0.045
response to corticosteroid GO:0031960 235 0.045
protein complex biogenesis GO:0070271 263 0.045
Mouse
response to peptide GO:1901652 292 0.045
circadian rhythm GO:0007623 88 0.044
nucleoside triphosphate metabolic process GO:0009141 144 0.044
Rat
organophosphate catabolic process GO:0046434 148 0.043
Rat
catabolic process GO:0009056 351 0.043
Rat
purine containing compound catabolic process GO:0072523 138 0.043
Rat
regulation of muscle system process GO:0090257 79 0.042
regulation of signal transduction GO:0009966 318 0.042
regulation of phosphorylation GO:0042325 248 0.042
organophosphate biosynthetic process GO:0090407 143 0.041
response to hexose GO:0009746 144 0.041
cell projection organization GO:0030030 302 0.040
g protein coupled receptor signaling pathway GO:0007186 242 0.039
response to reactive oxygen species GO:0000302 120 0.039
Rat
ribonucleotide catabolic process GO:0009261 136 0.038
Rat
actin filament based movement GO:0030048 16 0.038
cellular component assembly GO:0022607 360 0.038
Mouse
twitch skeletal muscle contraction GO:0014721 3 0.038
regulation of protein metabolic process GO:0051246 289 0.037
cellular divalent inorganic cation homeostasis GO:0072503 162 0.037
cellular ion homeostasis GO:0006873 184 0.037
organonitrogen compound catabolic process GO:1901565 179 0.037
Rat
organic substance catabolic process GO:1901575 316 0.037
Rat
ribonucleoside metabolic process GO:0009119 174 0.037
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.036
regulation of cellular protein metabolic process GO:0032268 267 0.036
negative regulation of apoptotic process GO:0043066 181 0.035
nucleotide catabolic process GO:0009166 139 0.035
Rat
response to estradiol GO:0032355 164 0.035
response to inorganic substance GO:0010035 377 0.035
ribonucleoside triphosphate metabolic process GO:0009199 141 0.035
Rat
single organism biosynthetic process GO:0044711 342 0.034
regulation of hydrolase activity GO:0051336 143 0.034
slow twitch skeletal muscle fiber contraction GO:0031444 2 0.034
cardiac muscle tissue morphogenesis GO:0055008 1 0.034
metal ion transport GO:0030001 289 0.034
regulation of sarcomere organization GO:0060297 2 0.033
Mouse
carboxylic acid metabolic process GO:0019752 289 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
purine ribonucleotide catabolic process GO:0009154 136 0.033
Rat
single organism organelle organization GO:1902589 180 0.033
Mouse
positive regulation of phosphorylation GO:0042327 177 0.032
apoptotic process GO:0006915 381 0.032
atp catabolic process GO:0006200 54 0.032
Rat
skeletal muscle tissue development GO:0007519 31 0.032
Mouse
cellular metal ion homeostasis GO:0006875 172 0.032
neurological system process GO:0050877 219 0.031
response to estrogen GO:0043627 232 0.031
negative regulation of programmed cell death GO:0043069 183 0.031
nucleoside metabolic process GO:0009116 179 0.031
Rat
cellular component movement GO:0006928 248 0.031
rna biosynthetic process GO:0032774 380 0.030
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.030
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
anatomical structure formation involved in morphogenesis GO:0048646 83 0.030
Mouse
regulation of cell proliferation GO:0042127 359 0.030
central nervous system development GO:0007417 311 0.030
programmed cell death GO:0012501 392 0.030
nucleobase containing compound catabolic process GO:0034655 152 0.030
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
response to nutrient levels GO:0031667 370 0.029
ribonucleoside catabolic process GO:0042454 126 0.029
Rat
calcium ion transport GO:0006816 131 0.029
neuron differentiation GO:0030182 368 0.028
aromatic compound catabolic process GO:0019439 168 0.028
Rat
cellular response to abiotic stimulus GO:0071214 85 0.028
cellular homeostasis GO:0019725 252 0.027
rna metabolic process GO:0016070 406 0.027
neuronal action potential GO:0019228 35 0.027
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.027
protein complex assembly GO:0006461 263 0.027
Mouse
response to monosaccharide GO:0034284 159 0.027
muscle filament sliding GO:0030049 2 0.027
ribonucleotide biosynthetic process GO:0009260 85 0.026
negative regulation of cellular biosynthetic process GO:0031327 161 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
nucleoside monophosphate catabolic process GO:0009125 56 0.026
Rat
muscle tissue morphogenesis GO:0060415 1 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
regulation of nucleotide metabolic process GO:0006140 117 0.025
heart morphogenesis GO:0003007 3 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
oxoacid metabolic process GO:0043436 290 0.025
mapk cascade GO:0000165 140 0.024
actin cytoskeleton organization GO:0030036 73 0.024
Mouse
positive regulation of protein metabolic process GO:0051247 178 0.024
macromolecular complex assembly GO:0065003 273 0.024
Mouse
regulation of mapk cascade GO:0043408 116 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
Mouse
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
ion homeostasis GO:0050801 212 0.023
single organism catabolic process GO:0044712 283 0.023
Rat
voluntary skeletal muscle contraction GO:0003010 3 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
cellular calcium ion homeostasis GO:0006874 160 0.022
cellular chemical homeostasis GO:0055082 247 0.022
purine nucleoside catabolic process GO:0006152 124 0.022
Rat
regulation of membrane potential GO:0042391 110 0.022
potassium ion transport GO:0006813 97 0.022
muscle structure development GO:0061061 87 0.022
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 122 0.022
Rat
regulation of blood circulation GO:1903522 110 0.022
intracellular transport GO:0046907 185 0.022
regulation of striated muscle contraction GO:0006942 21 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
muscle cell differentiation GO:0042692 52 0.021
Mouse
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.021
Rat
multicellular organismal signaling GO:0035637 44 0.021
atp metabolic process GO:0046034 72 0.021
Rat
transmission of nerve impulse GO:0019226 42 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
anterior posterior pattern specification GO:0009952 1 0.021
ribonucleoside monophosphate catabolic process GO:0009158 55 0.020
Rat
coronary vasculature morphogenesis GO:0060977 3 0.020
lipid metabolic process GO:0006629 283 0.020
response to ammonium ion GO:0060359 71 0.020
positive regulation of signal transduction GO:0009967 175 0.020
divalent metal ion transport GO:0070838 132 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
Rat
positive regulation of cell death GO:0010942 184 0.019
ras protein signal transduction GO:0007265 29 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
positive regulation of molecular function GO:0044093 230 0.019
protein complex subunit organization GO:0071822 302 0.019
Mouse
regulation of cell development GO:0060284 263 0.019
Mouse
cellular component biogenesis GO:0044085 368 0.019
Mouse
cellular response to organic cyclic compound GO:0071407 202 0.019
cardiac chamber development GO:0003205 1 0.019
proteolysis GO:0006508 175 0.019
tissue regeneration GO:0042246 36 0.018
response to peptide hormone GO:0043434 278 0.018
actin filament based process GO:0030029 86 0.018
Mouse
gastrulation GO:0007369 2 0.018
sequestering of metal ion GO:0051238 9 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
Rat
sequestering of calcium ion GO:0051208 8 0.018
calcium ion homeostasis GO:0055074 162 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
involuntary skeletal muscle contraction GO:0003011 2 0.018
cgmp biosynthetic process GO:0006182 15 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
regulation of tube size GO:0035150 89 0.017
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.017
action potential GO:0001508 54 0.017
multicellular organismal homeostasis GO:0048871 49 0.017
purine ribonucleotide biosynthetic process GO:0009152 81 0.017
neuromuscular process GO:0050905 2 0.017
response to bacterium GO:0009617 200 0.017
negative regulation of camp metabolic process GO:0030815 14 0.017
reproduction GO:0000003 245 0.017
heterocycle catabolic process GO:0046700 167 0.017
Rat
wound healing GO:0042060 122 0.017
purine nucleoside monophosphate catabolic process GO:0009128 55 0.017
Rat
divalent inorganic cation transport GO:0072511 134 0.017
diaphragm contraction GO:0002086 2 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
amine transport GO:0015837 57 0.016
head development GO:0060322 247 0.016
response to hypoxia GO:0001666 231 0.016
positive regulation of protein modification process GO:0031401 142 0.016
skeletal muscle contraction GO:0003009 17 0.016
b cell differentiation GO:0030183 2 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
Rat
behavior GO:0007610 205 0.016
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.016
sarcomere organization GO:0045214 6 0.016
Mouse
amine metabolic process GO:0009308 38 0.015
regulation of heart contraction GO:0008016 48 0.015
ribose phosphate biosynthetic process GO:0046390 87 0.015
regulation of cell differentiation GO:0045595 320 0.015
Mouse
single organism reproductive process GO:0044702 297 0.015
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.015
cellular amine metabolic process GO:0044106 38 0.015
response to growth factor GO:0070848 189 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
gland development GO:0048732 155 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
locomotion GO:0040011 237 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
vascular process in circulatory system GO:0003018 96 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
erythrocyte differentiation GO:0030218 1 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
organic acid metabolic process GO:0006082 292 0.015
regulation of ion transport GO:0043269 245 0.015
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.015
cellular response to growth factor stimulus GO:0071363 162 0.014
protein oligomerization GO:0051259 191 0.014
response to external biotic stimulus GO:0043207 221 0.014
negative regulation of ion transmembrane transporter activity GO:0032413 12 0.014
regulation of programmed cell death GO:0043067 341 0.014
cardiovascular system development GO:0072358 134 0.014
cyclic purine nucleotide metabolic process GO:0052652 62 0.014
cellular lipid metabolic process GO:0044255 208 0.014
positive regulation of fear response GO:1903367 3 0.014
response to lipopolysaccharide GO:0032496 191 0.014
metal ion homeostasis GO:0055065 186 0.014
cardiac muscle cell contraction GO:0086003 10 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
cell growth GO:0016049 104 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
female pregnancy GO:0007565 122 0.014
regulation of cardiac muscle contraction GO:0055117 17 0.014
response to cytokine GO:0034097 215 0.014
single organism intracellular transport GO:1902582 166 0.014
regeneration GO:0031099 163 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
negative regulation of signaling GO:0023057 157 0.013
response to extracellular stimulus GO:0009991 380 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
positive regulation of gtp catabolic process GO:0033126 48 0.013
regulation of homeostatic process GO:0032844 101 0.013
response to glucose GO:0009749 136 0.013
aging GO:0007568 241 0.013
regulation of transcription dna templated GO:0006355 374 0.013
formation of primary germ layer GO:0001704 1 0.013
response to vitamin GO:0033273 131 0.013
peptidyl amino acid modification GO:0018193 126 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
regulation of ion homeostasis GO:2000021 63 0.013
muscle organ development GO:0007517 50 0.013
Mouse
brain development GO:0007420 247 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
response to decreased oxygen levels GO:0036293 237 0.013
guanosine containing compound catabolic process GO:1901069 71 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
negative regulation of molecular function GO:0044092 133 0.013
cyclic nucleotide biosynthetic process GO:0009190 63 0.013
actomyosin structure organization GO:0031032 22 0.013
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
respiratory gaseous exchange GO:0007585 4 0.013
multi organism reproductive process GO:0044703 262 0.012
gtp metabolic process GO:0046039 72 0.012
cyclic nucleotide metabolic process GO:0009187 80 0.012
negative regulation of cell communication GO:0010648 158 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
dna metabolic process GO:0006259 96 0.012
adult locomotory behavior GO:0008344 4 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.012
sodium ion transmembrane transport GO:0035725 67 0.012
maintenance of location GO:0051235 17 0.012
cellular ketone metabolic process GO:0042180 51 0.012
vesicle mediated transport GO:0016192 181 0.012
nucleic acid templated transcription GO:0097659 379 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
positive regulation of gene expression GO:0010628 244 0.012
striated muscle cell development GO:0055002 26 0.012
Mouse
regulation of sequestering of calcium ion GO:0051282 26 0.012
lipid biosynthetic process GO:0008610 128 0.012
regulation of neurogenesis GO:0050767 247 0.012
cellular cation homeostasis GO:0030003 180 0.012
regulation of purine nucleotide catabolic process GO:0033121 65 0.012
regulation of cellular localization GO:0060341 263 0.012
regulation of catabolic process GO:0009894 113 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
neuron projection development GO:0031175 273 0.012
rho protein signal transduction GO:0007266 11 0.012
regulation of rna metabolic process GO:0051252 391 0.011
immune response GO:0006955 104 0.011
muscle cell proliferation GO:0033002 84 0.011
gtp catabolic process GO:0006184 71 0.011
regulation of actin filament based process GO:0032970 42 0.011
Mouse
l glutamate import GO:0051938 2 0.011
positive regulation of long term synaptic potentiation GO:1900273 4 0.011
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.011
cellular response to alcohol GO:0097306 87 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
cation homeostasis GO:0055080 195 0.011
cytoplasmic transport GO:0016482 115 0.011
response to other organism GO:0051707 220 0.011
cellular response to external stimulus GO:0071496 118 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
Rat
hepaticobiliary system development GO:0061008 90 0.011
striated muscle tissue development GO:0014706 58 0.011
Mouse
cell fate determination GO:0001709 2 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
positive regulation of gtpase activity GO:0043547 47 0.011
bmp signaling pathway GO:0030509 4 0.011
regulation of epithelial cell proliferation GO:0050678 49 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
regulation of organelle organization GO:0033043 80 0.011
Mouse
cellular response to cytokine stimulus GO:0071345 127 0.011
synaptic transmission GO:0007268 235 0.011
positive regulation of developmental process GO:0051094 283 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.010
Rat
cellular response to nitrogen compound GO:1901699 210 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.010
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
regulation of proteolysis GO:0030162 66 0.010
negative regulation of protein maturation GO:1903318 47 0.010
meiotic cell cycle process GO:1903046 3 0.010
cellular component assembly involved in morphogenesis GO:0010927 17 0.010
Mouse
mesoderm development GO:0007498 2 0.010
myelination GO:0042552 39 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
response to heat GO:0009408 60 0.010
Rat
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.010
regulation of transferase activity GO:0051338 123 0.010
single organism behavior GO:0044708 130 0.010
sensory perception of pain GO:0019233 73 0.010
rna localization GO:0006403 4 0.010
cellular protein complex assembly GO:0043623 44 0.010
Mouse

Myh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.316
musculoskeletal system disease DOID:17 0 0.316
muscular disease DOID:0080000 0 0.193
myopathy DOID:423 0 0.159
muscular dystrophy DOID:9884 0 0.159
muscle tissue disease DOID:66 0 0.159
heart disease DOID:114 0 0.051
cardiomyopathy DOID:0050700 0 0.051
intrinsic cardiomyopathy DOID:0060036 0 0.051
cardiovascular system disease DOID:1287 0 0.051
dilated cardiomyopathy DOID:12930 0 0.024
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.014
disease of metabolism DOID:0014667 0 0.013
retinal disease DOID:5679 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012