Rattus norvegicus

27 known processes

Myl3

myosin, light chain 3, alkali; ventricular, skeletal, slow

(Aliases: MGC93574,Mylc1v)

Myl3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle contraction GO:0006936 88 0.740
slow twitch skeletal muscle fiber contraction GO:0031444 2 0.492
twitch skeletal muscle contraction GO:0014721 3 0.489
cardiac muscle tissue morphogenesis GO:0055008 1 0.471
Human
actin myosin filament sliding GO:0033275 2 0.454
striated muscle contraction GO:0006941 44 0.328
muscle system process GO:0003012 115 0.320
muscle filament sliding GO:0030049 2 0.270
anatomical structure formation involved in morphogenesis GO:0048646 83 0.269
Zebrafish
myosin filament assembly GO:0031034 1 0.263
actin filament based movement GO:0030048 16 0.260
Fly
muscle tissue morphogenesis GO:0060415 1 0.251
Human
response to electrical stimulus involved in regulation of muscle adaptation GO:0014878 4 0.198
muscle organ morphogenesis GO:0048644 1 0.173
Human
circulatory system process GO:0003013 183 0.155
muscle structure development GO:0061061 87 0.154
actin mediated cell contraction GO:0070252 12 0.142
muscle tissue development GO:0060537 58 0.142
cellular component assembly involved in morphogenesis GO:0010927 17 0.133
Zebrafish
protein complex assembly GO:0006461 263 0.133
striated muscle cell development GO:0055002 26 0.113
Zebrafish
cell projection organization GO:0030030 302 0.102
cardiac ventricle development GO:0003231 1 0.099
Human
cellular component assembly GO:0022607 360 0.098
Zebrafish
circulatory system development GO:0072359 134 0.095
Human Zebrafish
striated muscle tissue development GO:0014706 58 0.089
catabolic process GO:0009056 351 0.088
cardiac chamber development GO:0003205 1 0.083
Human
cardiac muscle contraction GO:0060048 27 0.081
regulation of cellular component organization GO:0051128 368 0.080
regulation of system process GO:0044057 208 0.079
Human
ribonucleoside triphosphate metabolic process GO:0009199 141 0.078
cytoskeleton organization GO:0007010 111 0.078
Zebrafish
myosin filament organization GO:0031033 2 0.077
macromolecular complex assembly GO:0065003 273 0.077
organic substance catabolic process GO:1901575 316 0.077
regulation of neuron projection development GO:0010975 161 0.077
dendrite morphogenesis GO:0048813 43 0.076
cardiocyte differentiation GO:0035051 22 0.076
Zebrafish
cardiac muscle cell development GO:0055013 16 0.076
Zebrafish
protein complex biogenesis GO:0070271 263 0.075
ventricular cardiac muscle cell action potential GO:0086005 2 0.074
homeostatic process GO:0042592 331 0.071
cellular component morphogenesis GO:0032989 155 0.069
Zebrafish
protein complex subunit organization GO:0071822 302 0.069
glycosyl compound metabolic process GO:1901657 182 0.066
purine nucleoside monophosphate catabolic process GO:0009128 55 0.066
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.063
macromolecular complex subunit organization GO:0043933 339 0.063
immune system process GO:0002376 204 0.061
organelle organization GO:0006996 266 0.060
Zebrafish
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.060
regulation of blood circulation GO:1903522 110 0.060
Human
response to inorganic substance GO:0010035 377 0.059
rna metabolic process GO:0016070 406 0.054
glycosyl compound catabolic process GO:1901658 126 0.053
aromatic compound catabolic process GO:0019439 168 0.053
heart process GO:0003015 57 0.053
cellular catabolic process GO:0044248 295 0.053
purine nucleotide metabolic process GO:0006163 229 0.053
tissue development GO:0009888 252 0.052
cardiac myofibril assembly GO:0055003 1 0.052
Zebrafish
atp metabolic process GO:0046034 72 0.052
nucleoside catabolic process GO:0009164 126 0.052
ribonucleoside monophosphate metabolic process GO:0009161 88 0.051
carbohydrate derivative metabolic process GO:1901135 346 0.050
heart development GO:0007507 72 0.050
Human Zebrafish
purine containing compound catabolic process GO:0072523 138 0.050
nucleotide metabolic process GO:0009117 279 0.049
growth GO:0040007 165 0.049
muscle cell differentiation GO:0042692 52 0.049
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 119 0.048
anatomical structure morphogenesis GO:0009653 298 0.047
Human Zebrafish
regulation of neuron differentiation GO:0045664 208 0.047
organelle assembly GO:0070925 22 0.047
Zebrafish
cellular ion homeostasis GO:0006873 184 0.047
nucleoside phosphate metabolic process GO:0006753 283 0.047
nucleobase containing small molecule metabolic process GO:0055086 316 0.047
nucleoside metabolic process GO:0009116 179 0.046
nucleoside monophosphate metabolic process GO:0009123 93 0.046
rna biosynthetic process GO:0032774 380 0.045
purine nucleoside catabolic process GO:0006152 124 0.044
single organism catabolic process GO:0044712 283 0.042
nucleoside phosphate catabolic process GO:1901292 140 0.042
regulation of cell projection organization GO:0031344 175 0.042
heart morphogenesis GO:0003007 3 0.042
Human Zebrafish
cardiac muscle cell action potential GO:0086001 5 0.041
anion transport GO:0006820 178 0.041
nucleoside triphosphate catabolic process GO:0009143 123 0.041
purine ribonucleoside metabolic process GO:0046128 168 0.041
nucleic acid templated transcription GO:0097659 379 0.041
purine nucleoside metabolic process GO:0042278 169 0.040
atp catabolic process GO:0006200 54 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.039
actin filament based process GO:0030029 86 0.039
Zebrafish Fly
cellular component biogenesis GO:0044085 368 0.039
Zebrafish
nucleoside triphosphate metabolic process GO:0009141 144 0.039
nucleoside monophosphate catabolic process GO:0009125 56 0.038
carbohydrate derivative catabolic process GO:1901136 147 0.038
multicellular organismal movement GO:0050879 17 0.038
ribonucleotide catabolic process GO:0009261 136 0.037
organonitrogen compound catabolic process GO:1901565 179 0.037
ribonucleoside metabolic process GO:0009119 174 0.036
cellular component movement GO:0006928 248 0.036
Fly
organophosphate catabolic process GO:0046434 148 0.036
heart contraction GO:0060047 57 0.035
organophosphate metabolic process GO:0019637 370 0.035
ribonucleotide metabolic process GO:0009259 231 0.035
response to purine containing compound GO:0014074 126 0.034
regulation of rna metabolic process GO:0051252 391 0.034
regulation of neurogenesis GO:0050767 247 0.034
negative regulation of metabolic process GO:0009892 331 0.034
purine containing compound metabolic process GO:0072521 253 0.034
purine ribonucleoside catabolic process GO:0046130 124 0.034
regulation of cell growth GO:0001558 85 0.033
positive regulation of cellular component organization GO:0051130 200 0.033
purine nucleoside monophosphate metabolic process GO:0009126 84 0.032
regulation of cell differentiation GO:0045595 320 0.032
cell projection morphogenesis GO:0048858 123 0.032
regulation of muscle system process GO:0090257 79 0.031
Human
heterocycle catabolic process GO:0046700 167 0.031
organic cyclic compound catabolic process GO:1901361 175 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.030
ribose phosphate metabolic process GO:0019693 235 0.030
nucleobase containing compound catabolic process GO:0034655 152 0.030
ribonucleoside triphosphate catabolic process GO:0009203 122 0.030
cellular protein localization GO:0034613 122 0.030
purine ribonucleotide metabolic process GO:0009150 227 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.029
regeneration GO:0031099 163 0.029
neuron differentiation GO:0030182 368 0.029
locomotion GO:0040011 237 0.029
ribonucleoside monophosphate catabolic process GO:0009158 55 0.029
cell morphogenesis GO:0000902 142 0.029
sarcomere organization GO:0045214 6 0.028
Zebrafish
purine ribonucleotide catabolic process GO:0009154 136 0.028
cellular protein complex assembly GO:0043623 44 0.028
cardiovascular system development GO:0072358 134 0.028
Human Zebrafish
blood circulation GO:0008015 183 0.027
purine nucleoside triphosphate catabolic process GO:0009146 122 0.026
purine nucleotide catabolic process GO:0006195 136 0.026
metal ion homeostasis GO:0055065 186 0.026
cell adhesion GO:0007155 110 0.026
actin cytoskeleton organization GO:0030036 73 0.026
Zebrafish
dendrite development GO:0016358 72 0.025
cellular cation homeostasis GO:0030003 180 0.025
ribonucleoside catabolic process GO:0042454 126 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
multicellular organismal signaling GO:0035637 44 0.023
potassium ion transmembrane transport GO:0071805 71 0.023
cellular macromolecular complex assembly GO:0034622 58 0.023
axonogenesis GO:0007409 71 0.022
response to temperature stimulus GO:0009266 94 0.022
organ formation GO:0048645 3 0.022
cellular homeostasis GO:0019725 252 0.022
chemical homeostasis GO:0048878 292 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
amine metabolic process GO:0009308 38 0.022
positive regulation of apoptotic process GO:0043065 154 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
positive regulation of neuron projection development GO:0010976 99 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
regulation of actin filament based movement GO:1903115 12 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
insulin secretion GO:0030073 69 0.021
response to peptide GO:1901652 292 0.021
regulation of ion transport GO:0043269 245 0.021
organic acid metabolic process GO:0006082 292 0.021
neuron development GO:0048666 286 0.021
apoptotic process GO:0006915 381 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.021
response to heat GO:0009408 60 0.021
cell cell signaling GO:0007267 335 0.021
calcium ion homeostasis GO:0055074 162 0.020
developmental growth GO:0048589 100 0.020
response to biotic stimulus GO:0009607 226 0.020
actomyosin structure organization GO:0031032 22 0.020
Zebrafish
regulation of programmed cell death GO:0043067 341 0.020
regulation of potassium ion transport GO:0043266 29 0.020
regulation of membrane potential GO:0042391 110 0.020
neuron projection morphogenesis GO:0048812 122 0.019
central nervous system development GO:0007417 311 0.019
nucleotide catabolic process GO:0009166 139 0.019
regulation of molecular function GO:0065009 398 0.019
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.019
musculoskeletal movement GO:0050881 17 0.019
cardiac muscle tissue development GO:0048738 26 0.019
Human Zebrafish
negative regulation of gene expression GO:0010629 199 0.019
l glutamate import GO:0051938 2 0.018
regulation of nervous system development GO:0051960 264 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
programmed cell death GO:0012501 392 0.018
regulation of growth GO:0040008 105 0.018
response to nutrient levels GO:0031667 370 0.018
cation homeostasis GO:0055080 195 0.017
cellular amine metabolic process GO:0044106 38 0.017
negative regulation of cell development GO:0010721 82 0.017
axon development GO:0061564 96 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
oxoacid metabolic process GO:0043436 290 0.017
peptide secretion GO:0002790 86 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
negative regulation of nervous system development GO:0051961 79 0.017
regulation of dendrite development GO:0050773 59 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
proteolysis GO:0006508 175 0.017
cellular response to oxygen containing compound GO:1901701 386 0.016
ion homeostasis GO:0050801 212 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
response to metal ion GO:0010038 253 0.016
wound healing GO:0042060 122 0.016
regulation of blood pressure GO:0008217 83 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
regulation of cell development GO:0060284 263 0.015
potassium ion transport GO:0006813 97 0.015
sequestering of metal ion GO:0051238 9 0.015
reproductive process GO:0022414 372 0.015
tissue morphogenesis GO:0048729 22 0.015
Human
skeletal muscle contraction GO:0003009 17 0.015
protein tetramerization GO:0051262 38 0.015
regulation of heart rate GO:0002027 16 0.015
response to reactive oxygen species GO:0000302 120 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
positive regulation of neuron differentiation GO:0045666 126 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
cellular response to stress GO:0033554 269 0.014
antigen processing and presentation GO:0019882 2 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
neuron projection development GO:0031175 273 0.014
response to hydrogen peroxide GO:0042542 89 0.014
single organism organelle organization GO:1902589 180 0.014
Zebrafish
carboxylic acid metabolic process GO:0019752 289 0.014
regulation of transcription dna templated GO:0006355 374 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
regulation of rna biosynthetic process GO:2001141 381 0.013
intracellular transport GO:0046907 185 0.013
defense response GO:0006952 194 0.013
amide transport GO:0042886 105 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
transcription dna templated GO:0006351 377 0.013
inflammatory response GO:0006954 150 0.013
nitrogen compound transport GO:0071705 229 0.013
regulation of cellular component movement GO:0051270 150 0.013
positive regulation of cell development GO:0010720 176 0.013
sequestering of calcium ion GO:0051208 8 0.012
negative regulation of potassium ion transmembrane transport GO:1901380 3 0.012
regulation of axonogenesis GO:0050770 37 0.012
muscle organ development GO:0007517 50 0.012
cellular potassium ion transport GO:0071804 72 0.012
response to peptide hormone GO:0043434 278 0.012
regulation of heart contraction GO:0008016 48 0.012
Human
protein oligomerization GO:0051259 191 0.012
peptide transport GO:0015833 97 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
negative regulation of transport GO:0051051 136 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
response to ethanol GO:0045471 162 0.012
response to extracellular stimulus GO:0009991 380 0.012
adult locomotory behavior GO:0008344 4 0.012
embryonic axis specification GO:0000578 1 0.012
response to decreased oxygen levels GO:0036293 237 0.012
positive regulation of potassium ion transmembrane transport GO:1901381 4 0.011
single organism intracellular transport GO:1902582 166 0.011
response to organophosphorus GO:0046683 102 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
muscle cell development GO:0055001 26 0.011
Zebrafish
regulation of ion homeostasis GO:2000021 63 0.011
cellular ketone metabolic process GO:0042180 51 0.011
gliogenesis GO:0042063 93 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
cell part morphogenesis GO:0032990 123 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
organic anion transport GO:0015711 132 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
intracellular signal transduction GO:0035556 314 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
regulation of homeostatic process GO:0032844 101 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
response to cytokine GO:0034097 215 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
behavior GO:0007610 205 0.010
positive regulation of gene expression GO:0010628 244 0.010
regulation of phosphate metabolic process GO:0019220 349 0.010
carboxylic acid transport GO:0046942 115 0.010
establishment of tissue polarity GO:0007164 2 0.010
protein homooligomerization GO:0051260 91 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
regulation of phosphorus metabolic process GO:0051174 349 0.010
neuromuscular process GO:0050905 2 0.010
cell growth GO:0016049 104 0.010
cardiac muscle cell contraction GO:0086003 10 0.010
cell motility GO:0048870 202 0.010
metal ion transport GO:0030001 289 0.010
spermatogenesis GO:0007283 99 0.010

Myl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.825
Human
muscular disease DOID:0080000 0 0.825
Human
disease of anatomical entity DOID:7 0 0.825
Human
musculoskeletal system disease DOID:17 0 0.825
Human
muscle tissue disease DOID:66 0 0.825
Human
heart disease DOID:114 0 0.453
Human
cardiomyopathy DOID:0050700 0 0.453
Human
intrinsic cardiomyopathy DOID:0060036 0 0.453
Human
cardiovascular system disease DOID:1287 0 0.453
Human
dilated cardiomyopathy DOID:12930 0 0.389
hypertrophic cardiomyopathy DOID:11984 0 0.336
Human
muscular dystrophy DOID:9884 0 0.166
congenital heart disease DOID:1682 0 0.079
heart septal defect DOID:1681 0 0.079
disease of metabolism DOID:0014667 0 0.025
acquired metabolic disease DOID:0060158 0 0.025
obesity DOID:9970 0 0.021
nutrition disease DOID:374 0 0.021
overnutrition DOID:654 0 0.021
disease of cellular proliferation DOID:14566 0 0.013
primary ciliary dyskinesia DOID:9562 0 0.013
long qt syndrome DOID:2843 0 0.010