Rattus norvegicus

39 known processes

ND4

NADH dehydrogenase subunit 4

ND4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to metal ion GO:0010038 253 0.226
positive regulation of multicellular organismal process GO:0051240 387 0.196
protein complex biogenesis GO:0070271 263 0.192
oxoacid metabolic process GO:0043436 290 0.173
fatty acid metabolic process GO:0006631 99 0.157
positive regulation of response to stimulus GO:0048584 285 0.156
protein complex assembly GO:0006461 263 0.144
ion transmembrane transport GO:0034220 365 0.141
regulation of immunoglobulin production GO:0002637 4 0.140
regulation of protein metabolic process GO:0051246 289 0.134
interleukin 18 production GO:0032621 1 0.134
organic acid metabolic process GO:0006082 292 0.132
cellular component assembly GO:0022607 360 0.129
regulation of immunoglobulin secretion GO:0051023 1 0.128
protein phosphorylation GO:0006468 345 0.122
regulation of phosphorylation GO:0042325 248 0.119
secretion by cell GO:0032940 248 0.116
neuron differentiation GO:0030182 368 0.106
response to other organism GO:0051707 220 0.106
positive regulation of interleukin 18 production GO:0032741 1 0.104
positive regulation of signaling GO:0023056 270 0.100
regulation of molecular function GO:0065009 398 0.094
aging GO:0007568 241 0.094
blood circulation GO:0008015 183 0.092
single organism reproductive process GO:0044702 297 0.091
carboxylic acid metabolic process GO:0019752 289 0.090
circulatory system process GO:0003013 183 0.089
regulation of protein phosphorylation GO:0001932 183 0.088
protein complex subunit organization GO:0071822 302 0.088
positive regulation of intracellular signal transduction GO:1902533 138 0.083
positive regulation of molecular function GO:0044093 230 0.082
secretion GO:0046903 307 0.081
positive regulation of developmental process GO:0051094 283 0.080
regulation of phosphate metabolic process GO:0019220 349 0.079
reproductive process GO:0022414 372 0.078
cellular component biogenesis GO:0044085 368 0.077
cellular response to endogenous stimulus GO:0071495 377 0.076
positive regulation of apoptotic process GO:0043065 154 0.076
regulation of multicellular organismal development GO:2000026 376 0.075
cellular catabolic process GO:0044248 295 0.074
response to nutrient GO:0007584 248 0.072
cation transport GO:0006812 382 0.069
neuron death GO:0070997 127 0.067
regulation of protein modification process GO:0031399 194 0.067
macromolecular complex assembly GO:0065003 273 0.062
multi organism reproductive process GO:0044703 262 0.060
response to hyperoxia GO:0055093 45 0.058
cellular response to hormone stimulus GO:0032870 247 0.057
cellular response to cytokine stimulus GO:0071345 127 0.056
positive regulation of cell differentiation GO:0045597 217 0.054
regulation of phosphorus metabolic process GO:0051174 349 0.054
metal ion transport GO:0030001 289 0.053
intracellular signal transduction GO:0035556 314 0.053
heart morphogenesis GO:0003007 3 0.053
response to external biotic stimulus GO:0043207 221 0.052
muscle system process GO:0003012 115 0.051
cellular response to organonitrogen compound GO:0071417 197 0.051
positive regulation of protein metabolic process GO:0051247 178 0.051
organelle organization GO:0006996 266 0.050
homeostatic process GO:0042592 331 0.050
response to oxygen levels GO:0070482 265 0.050
response to extracellular stimulus GO:0009991 380 0.049
protein oligomerization GO:0051259 191 0.048
tissue development GO:0009888 252 0.048
behavior GO:0007610 205 0.047
lipid metabolic process GO:0006629 283 0.046
development of primary sexual characteristics GO:0045137 107 0.046
response to cytokine GO:0034097 215 0.046
positive regulation of cell communication GO:0010647 271 0.045
catabolic process GO:0009056 351 0.045
regulation of organelle organization GO:0033043 80 0.045
peptidyl amino acid modification GO:0018193 126 0.043
response to oxidative stress GO:0006979 186 0.043
ion homeostasis GO:0050801 212 0.043
cellular cation homeostasis GO:0030003 180 0.043
regulation of membrane potential GO:0042391 110 0.042
benzene containing compound metabolic process GO:0042537 22 0.042
positive regulation of cellular component organization GO:0051130 200 0.042
striated muscle contraction GO:0006941 44 0.042
immunoglobulin mediated immune response GO:0016064 4 0.041
cellular divalent inorganic cation homeostasis GO:0072503 162 0.041
regulation of blood vessel size GO:0050880 89 0.040
response to estrogen GO:0043627 232 0.040
gland development GO:0048732 155 0.040
response to wounding GO:0009611 254 0.040
cellular amino acid metabolic process GO:0006520 107 0.039
oxidation reduction process GO:0055114 304 0.039
divalent inorganic cation homeostasis GO:0072507 165 0.038
defecation GO:0030421 1 0.038
organic substance catabolic process GO:1901575 316 0.038
macromolecular complex subunit organization GO:0043933 339 0.038
sensory perception GO:0007600 101 0.037
long chain fatty acid metabolic process GO:0001676 32 0.036
regulation of cellular protein metabolic process GO:0032268 267 0.036
positive regulation of signal transduction GO:0009967 175 0.036
response to alkaloid GO:0043279 132 0.035
positive regulation of isotype switching GO:0045830 1 0.035
calcium ion homeostasis GO:0055074 162 0.035
protein homooligomerization GO:0051260 91 0.034
cellular response to external stimulus GO:0071496 118 0.034
regulation of cell differentiation GO:0045595 320 0.034
single organism organelle organization GO:1902589 180 0.034
positive regulation of neurogenesis GO:0050769 165 0.034
cytokine production GO:0001816 61 0.033
response to growth factor GO:0070848 189 0.033
insecticide metabolic process GO:0017143 4 0.033
regulation of intracellular signal transduction GO:1902531 218 0.032
purine ribonucleoside metabolic process GO:0046128 168 0.032
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.030
synaptic transmission GO:0007268 235 0.030
reproductive structure development GO:0048608 128 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
negative regulation of response to stimulus GO:0048585 155 0.030
regulation of catalytic activity GO:0050790 304 0.030
b cell activation involved in immune response GO:0002312 1 0.030
endosomal lumen acidification GO:0048388 1 0.030
response to carbohydrate GO:0009743 183 0.029
cellular chemical homeostasis GO:0055082 247 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
neuron development GO:0048666 286 0.029
actin filament based movement GO:0030048 16 0.029
response to mechanical stimulus GO:0009612 134 0.029
regulation of neuron death GO:1901214 115 0.029
positive regulation of leukocyte differentiation GO:1902107 13 0.029
regulation of nervous system development GO:0051960 264 0.029
organonitrogen compound catabolic process GO:1901565 179 0.029
response to reactive oxygen species GO:0000302 120 0.029
sulfur compound metabolic process GO:0006790 70 0.029
cellular homeostasis GO:0019725 252 0.028
response to biotic stimulus GO:0009607 226 0.028
circulatory system development GO:0072359 134 0.028
organophosphate metabolic process GO:0019637 370 0.028
response to lipopolysaccharide GO:0032496 191 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
cellular response to growth factor stimulus GO:0071363 162 0.028
regulation of rna metabolic process GO:0051252 391 0.028
positive regulation of immunoglobulin production GO:0002639 4 0.027
regulation of cell development GO:0060284 263 0.027
amine metabolic process GO:0009308 38 0.027
regulation of cellular component organization GO:0051128 368 0.027
cellular ion homeostasis GO:0006873 184 0.027
regulation of cell proliferation GO:0042127 359 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
positive regulation of transport GO:0051050 245 0.026
cellular lipid metabolic process GO:0044255 208 0.026
cation homeostasis GO:0055080 195 0.026
positive regulation of phosphorylation GO:0042327 177 0.026
immune system process GO:0002376 204 0.025
mapk cascade GO:0000165 140 0.025
single organism catabolic process GO:0044712 283 0.025
neuron projection development GO:0031175 273 0.025
ribonucleoside metabolic process GO:0009119 174 0.025
response to nicotine GO:0035094 51 0.024
chemical homeostasis GO:0048878 292 0.024
response to increased oxygen levels GO:0036296 45 0.024
response to corticosteroid GO:0031960 235 0.024
regulation of cytokine production GO:0001817 56 0.024
synaptic transmission glycinergic GO:0060012 2 0.024
developmental process involved in reproduction GO:0003006 159 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
response to antibiotic GO:0046677 39 0.023
immune response GO:0006955 104 0.023
regulation of transferase activity GO:0051338 123 0.023
growth GO:0040007 165 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.023
defense response GO:0006952 194 0.023
potassium ion transport GO:0006813 97 0.022
cellular amine metabolic process GO:0044106 38 0.022
cytoskeleton organization GO:0007010 111 0.022
cardiovascular system development GO:0072358 134 0.022
ossification GO:0001503 70 0.022
regulation of cellular component biogenesis GO:0044087 86 0.022
regulation of signal transduction GO:0009966 318 0.022
response to ketone GO:1901654 182 0.022
positive regulation of kinase activity GO:0033674 77 0.022
tissue remodeling GO:0048771 40 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
cellular response to alcohol GO:0097306 87 0.021
positive regulation of transferase activity GO:0051347 81 0.021
regulation of cellular component movement GO:0051270 150 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
regulation of behavior GO:0050795 61 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
positive regulation of secretion GO:0051047 140 0.021
sex differentiation GO:0007548 113 0.021
response to bacterium GO:0009617 200 0.020
positive regulation of gene expression GO:0010628 244 0.020
positive regulation of cytokine production GO:0001819 42 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
male gonad development GO:0008584 59 0.020
chemokine metabolic process GO:0050755 3 0.020
response to monosaccharide GO:0034284 159 0.020
response to estradiol GO:0032355 164 0.020
single organism biosynthetic process GO:0044711 342 0.020
divalent metal ion transport GO:0070838 132 0.020
nucleoside metabolic process GO:0009116 179 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
response to acid chemical GO:0001101 222 0.020
cell projection organization GO:0030030 302 0.019
hormone metabolic process GO:0042445 69 0.019
response to nutrient levels GO:0031667 370 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
leydig cell differentiation GO:0033327 8 0.019
regulation of ion transport GO:0043269 245 0.019
cell cell signaling GO:0007267 335 0.019
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.019
muscle contraction GO:0006936 88 0.019
regulation of neurogenesis GO:0050767 247 0.019
response to testosterone GO:0033574 55 0.018
b cell mediated immunity GO:0019724 4 0.018
positive regulation of nervous system development GO:0051962 178 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
positive regulation of protein kinase activity GO:0045860 73 0.018
immunoglobulin secretion GO:0048305 1 0.018
regulation of blood circulation GO:1903522 110 0.018
purine nucleoside catabolic process GO:0006152 124 0.018
regulation of kinase activity GO:0043549 117 0.018
vitamin d3 metabolic process GO:0070640 2 0.018
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 1 0.018
positive regulation of cell development GO:0010720 176 0.018
response to histamine GO:0034776 3 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
negative regulation of neuron death GO:1901215 69 0.018
response to peptide hormone GO:0043434 278 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
innate immune response GO:0045087 35 0.018
purine containing compound metabolic process GO:0072521 253 0.018
regulation of secretion by cell GO:1903530 208 0.017
central nervous system development GO:0007417 311 0.017
response to cadmium ion GO:0046686 35 0.017
cellular response to mechanical stimulus GO:0071260 48 0.017
response to inorganic substance GO:0010035 377 0.017
cell activation GO:0001775 97 0.017
respiratory system development GO:0060541 45 0.017
cellular ketone metabolic process GO:0042180 51 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
progesterone biosynthetic process GO:0006701 3 0.017
regulation of immune system process GO:0002682 123 0.017
regulation of mapk cascade GO:0043408 116 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
protein heterooligomerization GO:0051291 89 0.017
regulation of establishment of protein localization GO:0070201 69 0.017
ribonucleoside catabolic process GO:0042454 126 0.017
inflammatory response GO:0006954 150 0.017
response to decreased oxygen levels GO:0036293 237 0.016
regulation of cytokine biosynthetic process GO:0042035 3 0.016
nucleoside catabolic process GO:0009164 126 0.016
reproduction GO:0000003 245 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
appendage morphogenesis GO:0035107 4 0.016
actin mediated cell contraction GO:0070252 12 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
gliogenesis GO:0042063 93 0.016
response to fungicide GO:0060992 20 0.016
neuronal ion channel clustering GO:0045161 3 0.016
regulation of growth GO:0040008 105 0.016
localization of cell GO:0051674 202 0.016
regulation of response to stress GO:0080134 126 0.016
calcitriol biosynthetic process from calciol GO:0036378 2 0.016
divalent inorganic cation transport GO:0072511 134 0.016
response to gonadotropin GO:0034698 34 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
angiogenesis GO:0001525 53 0.015
negative regulation of transport GO:0051051 136 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
transcription dna templated GO:0006351 377 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
regulation of hormone levels GO:0010817 187 0.015
ovulation cycle GO:0042698 67 0.015
purine containing compound catabolic process GO:0072523 138 0.015
regulation of immunoglobulin mediated immune response GO:0002889 2 0.015
maternal process involved in female pregnancy GO:0060135 38 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
head development GO:0060322 247 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
regulation of muscle contraction GO:0006937 53 0.015
sexual reproduction GO:0019953 148 0.015
detection of stimulus GO:0051606 24 0.015
membrane organization GO:0061024 94 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
single organism behavior GO:0044708 130 0.015
regulation of isotype switching GO:0045191 1 0.015
multicellular organismal movement GO:0050879 17 0.015
regulation of membrane repolarization GO:0060306 1 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
hormone biosynthetic process GO:0042446 25 0.014
vasoconstriction GO:0042310 54 0.014
response to hexose GO:0009746 144 0.014
wound healing GO:0042060 122 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
cardiac muscle cell contraction GO:0086003 10 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
apoptotic process GO:0006915 381 0.014
regulation of homotypic cell cell adhesion GO:0034110 4 0.014
regulation of heart contraction GO:0008016 48 0.014
regulation of proteolysis GO:0030162 66 0.014
naphthalene metabolic process GO:0018931 2 0.014
regulation of b cell mediated immunity GO:0002712 2 0.014
negative regulation of cellular metabolic process GO:0031324 281 0.014
transmembrane transport GO:0055085 412 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
regulation of stress activated mapk cascade GO:0032872 23 0.014
cellular amide metabolic process GO:0043603 44 0.014
proteolysis GO:0006508 175 0.014
regulation of hydrolase activity GO:0051336 143 0.014
action potential GO:0001508 54 0.014
arachidonic acid metabolic process GO:0019369 20 0.014
response to dexamethasone GO:0071548 49 0.013
cation transmembrane transport GO:0098655 263 0.013
regulation of protein serine threonine kinase activity GO:0071900 64 0.013
cell cycle GO:0007049 101 0.013
gonad development GO:0008406 104 0.013
positive regulation of immune system process GO:0002684 90 0.013
regulation of cellular localization GO:0060341 263 0.013
trichloroethylene metabolic process GO:0018979 1 0.013
response to ethanol GO:0045471 162 0.013
lung development GO:0030324 43 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
regulation of protein kinase activity GO:0045859 105 0.013
regulation of transmembrane transport GO:0034762 122 0.013
steroid biosynthetic process GO:0006694 48 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.013
heterocycle catabolic process GO:0046700 167 0.013
lymphocyte activation involved in immune response GO:0002285 3 0.013
lipid biosynthetic process GO:0008610 128 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
serotonin receptor signaling pathway GO:0007210 10 0.013
cytokine mediated signaling pathway GO:0019221 43 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
response to glucose GO:0009749 136 0.013
negative regulation of l glutamate transport GO:0002037 1 0.013
response to fluid shear stress GO:0034405 16 0.013
heart development GO:0007507 72 0.013
neurological system process GO:0050877 219 0.013
secondary alcohol metabolic process GO:1902652 2 0.012
reproductive system development GO:0061458 128 0.012
sodium ion transmembrane transport GO:0035725 67 0.012
regulation of vasoconstriction GO:0019229 44 0.012
somatic diversification of immunoglobulins involved in immune response GO:0002208 1 0.012
cellular response to histamine GO:0071420 3 0.012
regulation of l glutamate transport GO:0002036 1 0.012
cellular response to stress GO:0033554 269 0.012
positive regulation of protein modification process GO:0031401 142 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
cellular response to tumor necrosis factor GO:0071356 46 0.012
regulation of metal ion transport GO:0010959 118 0.012
regulation of sodium ion transport GO:0002028 21 0.012
organophosphate catabolic process GO:0046434 148 0.012
cellular response to oxygen containing compound GO:1901701 386 0.012
response to vitamin GO:0033273 131 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
regulation of synaptic transmission GO:0050804 141 0.012
male gamete generation GO:0048232 99 0.012
lauric acid metabolic process GO:0048252 4 0.012
programmed cell death GO:0012501 392 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
neurotransmitter gated ion channel clustering GO:0072578 3 0.012
sensory perception of bitter taste GO:0050913 4 0.012
positive regulation of mapk cascade GO:0043410 92 0.011
dibenzo p dioxin metabolic process GO:0018894 10 0.011
bone remodeling GO:0046849 23 0.011
cellular protein complex assembly GO:0043623 44 0.011
regulation of apoptotic process GO:0042981 335 0.011
female pregnancy GO:0007565 122 0.011
lung alveolus development GO:0048286 6 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
regulation of system process GO:0044057 208 0.011
potassium ion transmembrane transport GO:0071805 71 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
positive regulation of epithelial cell proliferation GO:0050679 32 0.011
regulation of transcription dna templated GO:0006355 374 0.011
rna biosynthetic process GO:0032774 380 0.011
somatic cell dna recombination GO:0016444 2 0.011
regulation of secretion GO:0051046 224 0.011
glycerolipid metabolic process GO:0046486 67 0.011
nitrogen compound transport GO:0071705 229 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
response to interferon gamma GO:0034341 20 0.011
response to radiation GO:0009314 137 0.010
actin cytoskeleton organization GO:0030036 73 0.010
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
terpenoid metabolic process GO:0006721 37 0.010
jak stat cascade GO:0007259 26 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
response to heat GO:0009408 60 0.010
endocrine system development GO:0035270 30 0.010
vascular process in circulatory system GO:0003018 96 0.010
cellular alcohol biosynthetic process GO:0044108 2 0.010
hippocampus development GO:0021766 30 0.010
nucleotide catabolic process GO:0009166 139 0.010
regulation of vesicle mediated transport GO:0060627 81 0.010
androgen biosynthetic process GO:0006702 10 0.010
aromatic compound catabolic process GO:0019439 168 0.010
synaptic vesicle exocytosis GO:0016079 15 0.010
cellular response to nutrient levels GO:0031669 60 0.010
eosinophil chemotaxis GO:0048245 3 0.010
cell cycle process GO:0022402 57 0.010
gastric motility GO:0035482 3 0.010
cellular component movement GO:0006928 248 0.010

ND4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
cardiovascular system disease DOID:1287 0 0.014
central nervous system disease DOID:331 0 0.013
nervous system disease DOID:863 0 0.013