Rattus norvegicus

0 known processes

Nae1

NEDD8 activating enzyme E1 subunit 1

(Aliases: Appbp1)

Nae1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 295 0.271
organophosphate metabolic process GO:0019637 370 0.256
purine nucleotide catabolic process GO:0006195 136 0.251
organophosphate biosynthetic process GO:0090407 143 0.141
ribose phosphate metabolic process GO:0019693 235 0.112
nucleotide catabolic process GO:0009166 139 0.109
purine nucleoside metabolic process GO:0042278 169 0.095
nucleoside triphosphate metabolic process GO:0009141 144 0.082
single organism catabolic process GO:0044712 283 0.077
carbohydrate derivative catabolic process GO:1901136 147 0.077
rna metabolic process GO:0016070 406 0.076
negative regulation of cellular biosynthetic process GO:0031327 161 0.075
nucleoside catabolic process GO:0009164 126 0.075
catabolic process GO:0009056 351 0.074
purine nucleotide metabolic process GO:0006163 229 0.073
organic substance catabolic process GO:1901575 316 0.071
regulation of rna metabolic process GO:0051252 391 0.070
glycosyl compound catabolic process GO:1901658 126 0.067
purine nucleoside catabolic process GO:0006152 124 0.066
transcription from rna polymerase ii promoter GO:0006366 252 0.065
nucleotide metabolic process GO:0009117 279 0.065
cellular amine metabolic process GO:0044106 38 0.064
purine ribonucleotide catabolic process GO:0009154 136 0.062
nucleoside phosphate catabolic process GO:1901292 140 0.061
heterocycle catabolic process GO:0046700 167 0.060
protein complex biogenesis GO:0070271 263 0.055
carbohydrate derivative metabolic process GO:1901135 346 0.055
vesicle mediated transport GO:0016192 181 0.053
ribonucleoside triphosphate metabolic process GO:0009199 141 0.051
aromatic compound catabolic process GO:0019439 168 0.051
purine containing compound metabolic process GO:0072521 253 0.050
nucleobase containing compound catabolic process GO:0034655 152 0.049
locomotion GO:0040011 237 0.048
purine ribonucleotide metabolic process GO:0009150 227 0.048
ribonucleoside catabolic process GO:0042454 126 0.047
nucleoside triphosphate catabolic process GO:0009143 123 0.046
organic hydroxy compound metabolic process GO:1901615 115 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
single organism biosynthetic process GO:0044711 342 0.044
macromolecular complex subunit organization GO:0043933 339 0.043
nucleoside metabolic process GO:0009116 179 0.043
nucleic acid templated transcription GO:0097659 379 0.043
protein modification by small protein conjugation or removal GO:0070647 35 0.042
ribonucleoside metabolic process GO:0009119 174 0.042
nucleoside monophosphate metabolic process GO:0009123 93 0.042
purine nucleoside triphosphate metabolic process GO:0009144 141 0.041
organonitrogen compound catabolic process GO:1901565 179 0.041
organic cyclic compound catabolic process GO:1901361 175 0.038
cellular nitrogen compound catabolic process GO:0044270 163 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
phosphatidylethanolamine metabolic process GO:0046337 1 0.036
amine metabolic process GO:0009308 38 0.036
protein complex subunit organization GO:0071822 302 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.036
cellular component biogenesis GO:0044085 368 0.035
single organism intracellular transport GO:1902582 166 0.034
nucleoside phosphate metabolic process GO:0006753 283 0.034
macromolecular complex assembly GO:0065003 273 0.034
ribonucleotide metabolic process GO:0009259 231 0.034
glycosyl compound metabolic process GO:1901657 182 0.033
negative regulation of rna metabolic process GO:0051253 123 0.032
reproductive process GO:0022414 372 0.032
neurological system process GO:0050877 219 0.031
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.031
neuron development GO:0048666 286 0.030
protein localization GO:0008104 191 0.030
purine nucleoside triphosphate catabolic process GO:0009146 122 0.029
ribonucleoside monophosphate metabolic process GO:0009161 88 0.029
ribonucleotide catabolic process GO:0009261 136 0.028
purine containing compound catabolic process GO:0072523 138 0.028
protein complex assembly GO:0006461 263 0.028
rna biosynthetic process GO:0032774 380 0.027
cell motility GO:0048870 202 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.026
transcription dna templated GO:0006351 377 0.026
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
purine ribonucleoside catabolic process GO:0046130 124 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.024
purine nucleoside monophosphate catabolic process GO:0009128 55 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.022
cellular component movement GO:0006928 248 0.022
lipid metabolic process GO:0006629 283 0.022
neuron differentiation GO:0030182 368 0.022
transmembrane transport GO:0055085 412 0.021
cytoplasmic transport GO:0016482 115 0.021
trna metabolic process GO:0006399 4 0.021
programmed cell death GO:0012501 392 0.021
ribonucleoside triphosphate catabolic process GO:0009203 122 0.021
organic hydroxy compound biosynthetic process GO:1901617 51 0.020
cellular component assembly GO:0022607 360 0.020
neuron projection development GO:0031175 273 0.020
single organism reproductive process GO:0044702 297 0.020
protein transport GO:0015031 132 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
cellular protein localization GO:0034613 122 0.019
localization of cell GO:0051674 202 0.019
small molecule biosynthetic process GO:0044283 124 0.019
organophosphate catabolic process GO:0046434 148 0.019
nucleoside monophosphate catabolic process GO:0009125 56 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
phospholipid biosynthetic process GO:0008654 29 0.018
atp metabolic process GO:0046034 72 0.018
alcohol metabolic process GO:0006066 77 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
macromolecule catabolic process GO:0009057 58 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
gamete generation GO:0007276 124 0.017
negative regulation of cell death GO:0060548 229 0.017
regulation of transcription dna templated GO:0006355 374 0.017
regulation of catabolic process GO:0009894 113 0.017
reproduction GO:0000003 245 0.017
positive regulation of nervous system development GO:0051962 178 0.017
multicellular organismal signaling GO:0035637 44 0.016
regulation of cellular component organization GO:0051128 368 0.016
small molecule catabolic process GO:0044282 59 0.016
cellular lipid metabolic process GO:0044255 208 0.016
lipid biosynthetic process GO:0008610 128 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.015
intracellular transport GO:0046907 185 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
ribonucleoside monophosphate catabolic process GO:0009158 55 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
mitochondrion organization GO:0007005 35 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
protein localization to organelle GO:0033365 57 0.014
organelle organization GO:0006996 266 0.014
response to metal ion GO:0010038 253 0.014
purine nucleobase metabolic process GO:0006144 4 0.014
regulation of locomotion GO:0040012 148 0.014
regulation of cell motility GO:2000145 131 0.014
macromolecule localization GO:0033036 252 0.014
oxidation reduction process GO:0055114 304 0.014
developmental process involved in reproduction GO:0003006 159 0.013
guanosine containing compound catabolic process GO:1901069 71 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
receptor mediated endocytosis GO:0006898 42 0.013
purine nucleoside monophosphate metabolic process GO:0009126 84 0.013
cellular macromolecule localization GO:0070727 122 0.013
ncrna processing GO:0034470 3 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
regulation of protein metabolic process GO:0051246 289 0.012
regulation of apoptotic process GO:0042981 335 0.012
response to acid chemical GO:0001101 222 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
male gamete generation GO:0048232 99 0.012
cell migration GO:0016477 197 0.012
sexual reproduction GO:0019953 148 0.012
reproductive system development GO:0061458 128 0.012
multi organism reproductive process GO:0044703 262 0.011
cell projection organization GO:0030030 302 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
regulation of cell proliferation GO:0042127 359 0.011
transmission of nerve impulse GO:0019226 42 0.011
regulation of dopamine metabolic process GO:0042053 5 0.011
establishment of protein localization GO:0045184 141 0.011
regulation of programmed cell death GO:0043067 341 0.011
neuronal action potential GO:0019228 35 0.011
cell morphogenesis GO:0000902 142 0.011
dorsal ventral pattern formation GO:0009953 4 0.011
negative regulation of metabolic process GO:0009892 331 0.011
intracellular protein transport GO:0006886 79 0.010
circulatory system process GO:0003013 183 0.010
central nervous system development GO:0007417 311 0.010
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 3 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
response to lithium ion GO:0010226 28 0.010

Nae1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
disease of anatomical entity DOID:7 0 0.022
reproductive system disease DOID:15 0 0.022
premature ovarian failure DOID:5426 0 0.022
female reproductive system disease DOID:229 0 0.022
ovarian disease DOID:1100 0 0.022
inherited metabolic disorder DOID:655 0 0.014
cognitive disorder DOID:1561 0 0.012
disease of mental health DOID:150 0 0.012