Rattus norvegicus

0 known processes

Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

(Aliases: MGC93795)

Ndufs1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
acetyl coa biosynthetic process from pyruvate GO:0006086 5 0.959
acyl coa biosynthetic process GO:0071616 7 0.821
energy derivation by oxidation of organic compounds GO:0015980 46 0.777
Human
acetyl coa biosynthetic process GO:0006085 6 0.767
sulfur compound biosynthetic process GO:0044272 19 0.746
cofactor biosynthetic process GO:0051188 28 0.701
dicarboxylic acid metabolic process GO:0043648 42 0.696
carboxylic acid metabolic process GO:0019752 289 0.661
oxoacid metabolic process GO:0043436 290 0.601
thioester biosynthetic process GO:0035384 7 0.553
generation of precursor metabolites and energy GO:0006091 62 0.522
Human
coenzyme metabolic process GO:0006732 86 0.306
acyl coa metabolic process GO:0006637 28 0.261
organic acid metabolic process GO:0006082 292 0.241
pyruvate metabolic process GO:0006090 27 0.237
cofactor metabolic process GO:0051186 95 0.211
oxidation reduction process GO:0055114 304 0.201
Human
coenzyme biosynthetic process GO:0009108 22 0.193
nucleobase containing small molecule metabolic process GO:0055086 316 0.177
Human
transmembrane transport GO:0055085 412 0.165
response to decreased oxygen levels GO:0036293 237 0.156
cellular respiration GO:0045333 21 0.150
Human
sulfur compound metabolic process GO:0006790 70 0.144
nucleoside phosphate metabolic process GO:0006753 283 0.139
Human
monocarboxylic acid metabolic process GO:0032787 152 0.124
aerobic respiration GO:0009060 13 0.119
thioester metabolic process GO:0035383 28 0.118
apoptotic process GO:0006915 381 0.113
Human
cell redox homeostasis GO:0045454 1 0.112
programmed cell death GO:0012501 392 0.103
Human
nucleotide metabolic process GO:0009117 279 0.101
Human
response to oxygen levels GO:0070482 265 0.099
reactive oxygen species metabolic process GO:0072593 37 0.099
Human
citrate metabolic process GO:0006101 3 0.096
mitochondrial calcium ion transport GO:0006851 2 0.095
cellular homeostasis GO:0019725 252 0.089
regulation of cell proliferation GO:0042127 359 0.083
ribonucleoside metabolic process GO:0009119 174 0.080
Human
acetyl coa metabolic process GO:0006084 17 0.076
homeostatic process GO:0042592 331 0.074
regulation of molecular function GO:0065009 398 0.073
nitrogen compound transport GO:0071705 229 0.072
response to molecule of bacterial origin GO:0002237 194 0.068
purine nucleoside metabolic process GO:0042278 169 0.067
Human
regulation of protein oligomerization GO:0032459 2 0.060
ion transmembrane transport GO:0034220 365 0.057
atp synthesis coupled electron transport GO:0042773 2 0.052
aging GO:0007568 241 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.048
purine ribonucleoside metabolic process GO:0046128 168 0.047
Human
rhythmic process GO:0048511 156 0.045
response to transition metal nanoparticle GO:1990267 122 0.041
macromolecular complex subunit organization GO:0043933 339 0.040
single organism organelle organization GO:1902589 180 0.038
tricarboxylic acid cycle GO:0006099 11 0.037
positive regulation of secretion by cell GO:1903532 128 0.036
regulation of apoptotic process GO:0042981 335 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
regulation of cellular component organization GO:0051128 368 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.034
Human
regulation of catalytic activity GO:0050790 304 0.034
metal ion transport GO:0030001 289 0.033
sleep GO:0030431 30 0.033
ion homeostasis GO:0050801 212 0.033
tricarboxylic acid metabolic process GO:0072350 10 0.033
organophosphate metabolic process GO:0019637 370 0.033
Human
single organism catabolic process GO:0044712 283 0.032
regulation of nervous system development GO:0051960 264 0.031
epithelium development GO:0060429 96 0.030
response to interleukin 1 GO:0070555 55 0.029
multi multicellular organism process GO:0044706 138 0.028
placenta development GO:0001890 22 0.028
response to monosaccharide GO:0034284 159 0.027
response to cold GO:0009409 29 0.027
chemical homeostasis GO:0048878 292 0.026
glycosyl compound metabolic process GO:1901657 182 0.026
Human
regulation of membrane potential GO:0042391 110 0.025
Human
positive regulation of response to stimulus GO:0048584 285 0.025
tissue development GO:0009888 252 0.025
response to external biotic stimulus GO:0043207 221 0.024
response to inorganic substance GO:0010035 377 0.024
negative regulation of metabolic process GO:0009892 331 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
regulation of protein metabolic process GO:0051246 289 0.023
neurological system process GO:0050877 219 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
isocitrate metabolic process GO:0006102 5 0.023
divalent metal ion transport GO:0070838 132 0.023
carbohydrate homeostasis GO:0033500 75 0.023
response to reactive oxygen species GO:0000302 120 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
nucleic acid transport GO:0050657 3 0.022
immune system process GO:0002376 204 0.022
regulation of programmed cell death GO:0043067 341 0.022
regulation of cellular localization GO:0060341 263 0.021
cation transmembrane transport GO:0098655 263 0.021
response to lipopolysaccharide GO:0032496 191 0.021
response to carbohydrate GO:0009743 183 0.021
negative regulation of cell death GO:0060548 229 0.021
response to nutrient levels GO:0031667 370 0.021
regulation of homotypic cell cell adhesion GO:0034110 4 0.020
growth GO:0040007 165 0.020
oxidoreduction coenzyme metabolic process GO:0006733 31 0.020
response to peptide hormone GO:0043434 278 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
nucleoside metabolic process GO:0009116 179 0.019
Human
cellular component biogenesis GO:0044085 368 0.019
positive regulation of molecular function GO:0044093 230 0.019
regulation of leukocyte activation GO:0002694 45 0.019
regulation of cell differentiation GO:0045595 320 0.019
negative regulation of programmed cell death GO:0043069 183 0.018
oxidative phosphorylation GO:0006119 4 0.018
macromolecular complex assembly GO:0065003 273 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
Human
nucleic acid templated transcription GO:0097659 379 0.018
glucose homeostasis GO:0042593 75 0.018
response to estrogen GO:0043627 232 0.018
female pregnancy GO:0007565 122 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
positive regulation of immune system process GO:0002684 90 0.017
response to acid chemical GO:0001101 222 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
purine containing compound metabolic process GO:0072521 253 0.017
Human
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
Human
alpha amino acid metabolic process GO:1901605 71 0.017
multicellular organismal response to stress GO:0033555 25 0.016
regulation of secretion by cell GO:1903530 208 0.016
response to other organism GO:0051707 220 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
protein localization GO:0008104 191 0.016
cellular chemical homeostasis GO:0055082 247 0.016
cation homeostasis GO:0055080 195 0.016
heterocycle catabolic process GO:0046700 167 0.016
positive regulation of lymphocyte activation GO:0051251 25 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
Human
calcium ion transport GO:0006816 131 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
positive regulation of mitochondrion organization GO:0010822 4 0.014
regulation of ion transport GO:0043269 245 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
circadian regulation of gene expression GO:0032922 3 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
Human
rna biosynthetic process GO:0032774 380 0.014
endocytosis GO:0006897 84 0.014
behavior GO:0007610 205 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
regulation of transmembrane transport GO:0034762 122 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
response to extracellular stimulus GO:0009991 380 0.014
response to bacterium GO:0009617 200 0.014
cellular component assembly GO:0022607 360 0.014
regulation of transferase activity GO:0051338 123 0.014
positive regulation of erythrocyte aggregation GO:0034120 1 0.014
positive regulation of cell differentiation GO:0045597 217 0.013
valine metabolic process GO:0006573 1 0.013
peptide transport GO:0015833 97 0.013
response to oxidative stress GO:0006979 186 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
circulatory system process GO:0003013 183 0.013
protein complex assembly GO:0006461 263 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
rna metabolic process GO:0016070 406 0.012
metal ion homeostasis GO:0055065 186 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
regulation of phosphorylation GO:0042325 248 0.012
cellular amine metabolic process GO:0044106 38 0.012
response to hydrogen peroxide GO:0042542 89 0.012
regulation of blood circulation GO:1903522 110 0.012
membrane repolarization GO:0086009 1 0.012
programmed necrotic cell death GO:0097300 2 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
cation transport GO:0006812 382 0.012
udp glucose metabolic process GO:0006011 3 0.012
protein complex subunit organization GO:0071822 302 0.012
positive regulation of fear response GO:1903367 3 0.012
regulation of transcription dna templated GO:0006355 374 0.011
positive regulation of signaling GO:0023056 270 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of hormone secretion GO:0046883 106 0.011
response to toxic substance GO:0009636 133 0.011
cellular ion homeostasis GO:0006873 184 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
branched chain amino acid catabolic process GO:0009083 4 0.011
atp metabolic process GO:0046034 72 0.011
Human
2 oxoglutarate metabolic process GO:0006103 6 0.011
positive regulation of peptide hormone secretion GO:0090277 50 0.011
epithelial cell differentiation GO:0030855 71 0.011
negative regulation of neuron death GO:1901215 69 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
Human
cellular response to reactive oxygen species GO:0034614 55 0.011
positive regulation of release of cytochrome c from mitochondria GO:0090200 3 0.011
signal release GO:0023061 145 0.011
protein oligomerization GO:0051259 191 0.011
cellular polysaccharide metabolic process GO:0044264 23 0.011
regulation of immune system process GO:0002682 123 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
single organism behavior GO:0044708 130 0.011
positive regulation of developmental process GO:0051094 283 0.011
organelle organization GO:0006996 266 0.010
Human
response to hexose GO:0009746 144 0.010
response to hypoxia GO:0001666 231 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
regulation of blood pressure GO:0008217 83 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010

Ndufs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.118
retinal degeneration DOID:8466 0 0.118
sensory system disease DOID:0050155 0 0.118
disease of anatomical entity DOID:7 0 0.118
retinitis pigmentosa DOID:10584 0 0.118
eye and adnexa disease DOID:1492 0 0.118
nervous system disease DOID:863 0 0.118
eye disease DOID:5614 0 0.118
disease of metabolism DOID:0014667 0 0.099
amino acid metabolic disorder DOID:9252 0 0.099
inherited metabolic disorder DOID:655 0 0.099
organic acidemia DOID:0060159 0 0.099
maple syrup urine disease DOID:9269 0 0.069