Rattus norvegicus

0 known processes

Nid2

nidogen 2

(Aliases: NID-2)

Nid2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.278
response to acid chemical GO:0001101 222 0.157
response to oxidative stress GO:0006979 186 0.146
cellular response to hormone stimulus GO:0032870 247 0.109
cellular response to organic cyclic compound GO:0071407 202 0.097
cellular response to organonitrogen compound GO:0071417 197 0.096
response to extracellular stimulus GO:0009991 380 0.095
response to peptide GO:1901652 292 0.081
biological adhesion GO:0022610 110 0.079
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.078
cellular response to peptide GO:1901653 133 0.076
response to estrogen GO:0043627 232 0.069
cellular response to acid chemical GO:0071229 75 0.066
cellular response to tumor necrosis factor GO:0071356 46 0.065
positive regulation of multicellular organismal process GO:0051240 387 0.065
response to vitamin e GO:0033197 24 0.065
cellular response to lipid GO:0071396 201 0.063
response to oxygen levels GO:0070482 265 0.061
response to reactive oxygen species GO:0000302 120 0.060
aorta development GO:0035904 2 0.058
regulation of cellular component organization GO:0051128 368 0.057
regulation of cell development GO:0060284 263 0.057
response to transforming growth factor beta GO:0071559 46 0.055
regulation of anatomical structure morphogenesis GO:0022603 141 0.052
behavior GO:0007610 205 0.051
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.051
response to mechanical stimulus GO:0009612 134 0.050
cellular response to nitrogen compound GO:1901699 210 0.049
response to ionizing radiation GO:0010212 59 0.049
cell adhesion GO:0007155 110 0.048
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.047
tissue development GO:0009888 252 0.047
immune response GO:0006955 104 0.046
response to estradiol GO:0032355 164 0.045
macromolecular complex subunit organization GO:0043933 339 0.045
response to hyperoxia GO:0055093 45 0.044
chemical homeostasis GO:0048878 292 0.044
response to peptide hormone GO:0043434 278 0.044
regulation of multicellular organismal development GO:2000026 376 0.043
negative regulation of developmental process GO:0051093 125 0.043
carboxylic acid metabolic process GO:0019752 289 0.042
formation of primary germ layer GO:0001704 1 0.041
cellular response to cytokine stimulus GO:0071345 127 0.038
response to hydrogen peroxide GO:0042542 89 0.038
cation transport GO:0006812 382 0.038
response to nutrient GO:0007584 248 0.036
regulation of cell motility GO:2000145 131 0.036
cellular response to retinoic acid GO:0071300 27 0.036
cellular response to oxygen containing compound GO:1901701 386 0.035
response to alkaloid GO:0043279 132 0.034
regulation of protein metabolic process GO:0051246 289 0.033
positive regulation of protein metabolic process GO:0051247 178 0.033
cellular response to growth factor stimulus GO:0071363 162 0.032
response to growth factor GO:0070848 189 0.032
endochondral bone morphogenesis GO:0060350 7 0.031
cellular response to stress GO:0033554 269 0.031
positive regulation of cellular component organization GO:0051130 200 0.031
rna metabolic process GO:0016070 406 0.030
regulation of cell differentiation GO:0045595 320 0.030
response to tumor necrosis factor GO:0034612 56 0.030
positive regulation of cell differentiation GO:0045597 217 0.029
response to radiation GO:0009314 137 0.029
response to camp GO:0051591 91 0.029
cellular response to nicotine GO:0071316 7 0.029
negative regulation of biosynthetic process GO:0009890 168 0.029
neuron development GO:0048666 286 0.029
regulation of neuron apoptotic process GO:0043523 83 0.028
cellular response to vitamin GO:0071295 21 0.028
response to nutrient levels GO:0031667 370 0.028
growth plate cartilage development GO:0003417 2 0.027
tube development GO:0035295 89 0.027
response to metal ion GO:0010038 253 0.027
neurological system process GO:0050877 219 0.027
cardiovascular system development GO:0072358 134 0.027
immune system process GO:0002376 204 0.027
anion transport GO:0006820 178 0.027
regulation of cellular localization GO:0060341 263 0.026
positive regulation of cell development GO:0010720 176 0.026
cellular response to fluid shear stress GO:0071498 4 0.025
intracellular signal transduction GO:0035556 314 0.025
response to hypoxia GO:0001666 231 0.025
neuron apoptotic process GO:0051402 88 0.025
macromolecular complex assembly GO:0065003 273 0.025
cellular component movement GO:0006928 248 0.025
protein oligomerization GO:0051259 191 0.025
cell projection organization GO:0030030 302 0.025
response to transition metal nanoparticle GO:1990267 122 0.025
protein complex subunit organization GO:0071822 302 0.024
extracellular structure organization GO:0043062 13 0.024
response to organophosphorus GO:0046683 102 0.024
gastrulation GO:0007369 2 0.024
protein complex biogenesis GO:0070271 263 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
apoptotic process GO:0006915 381 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
regulation of canonical wnt signaling pathway GO:0060828 4 0.023
regulation of secretion GO:0051046 224 0.023
single organism biosynthetic process GO:0044711 342 0.023
regulation of neurogenesis GO:0050767 247 0.023
regulation of cell projection organization GO:0031344 175 0.023
ras protein signal transduction GO:0007265 29 0.023
cellular response to peptide hormone stimulus GO:0071375 120 0.023
response to fluoride GO:1902617 3 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
response to toxic substance GO:0009636 133 0.022
cell cell signaling GO:0007267 335 0.022
cellular response to abiotic stimulus GO:0071214 85 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
regulation of phosphorylation GO:0042325 248 0.022
response to decreased oxygen levels GO:0036293 237 0.022
regulation of vasculature development GO:1901342 44 0.021
amine metabolic process GO:0009308 38 0.021
negative regulation of gene expression GO:0010629 199 0.021
regulation of apoptotic process GO:0042981 335 0.021
regulation of neuron death GO:1901214 115 0.021
regulation of nervous system development GO:0051960 264 0.021
response to wounding GO:0009611 254 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cellular amine metabolic process GO:0044106 38 0.020
cell motility GO:0048870 202 0.020
aging GO:0007568 241 0.020
blood circulation GO:0008015 183 0.020
response to ketone GO:1901654 182 0.020
extracellular fibril organization GO:0043206 1 0.020
response to vitamin GO:0033273 131 0.020
regulation of system process GO:0044057 208 0.020
positive regulation of transport GO:0051050 245 0.020
response to insulin GO:0032868 133 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
cell morphogenesis GO:0000902 142 0.019
regulation of metal ion transport GO:0010959 118 0.019
camera type eye morphogenesis GO:0048593 2 0.019
endochondral bone growth GO:0003416 3 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
regulation of neuron projection development GO:0010975 161 0.019
blood vessel development GO:0001568 69 0.019
renal system development GO:0072001 67 0.019
cartilage development involved in endochondral bone morphogenesis GO:0060351 3 0.019
multi organism reproductive process GO:0044703 262 0.018
response to increased oxygen levels GO:0036296 45 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
positive regulation of nervous system development GO:0051962 178 0.018
oxoacid metabolic process GO:0043436 290 0.018
organic substance catabolic process GO:1901575 316 0.018
positive regulation of protein modification process GO:0031401 142 0.018
ion transmembrane transport GO:0034220 365 0.018
eye morphogenesis GO:0048592 4 0.018
developmental growth involved in morphogenesis GO:0060560 33 0.018
transmembrane transport GO:0055085 412 0.018
positive regulation of stem cell differentiation GO:2000738 2 0.018
action potential GO:0001508 54 0.017
response to amino acid GO:0043200 75 0.017
cellular response to external stimulus GO:0071496 118 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.017
regulation of programmed cell death GO:0043067 341 0.017
organ regeneration GO:0031100 101 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
metanephric mesenchymal cell migration GO:0035789 2 0.017
cell type specific apoptotic process GO:0097285 134 0.017
cellular component assembly GO:0022607 360 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
s shaped body morphogenesis GO:0072050 2 0.017
cellular homeostasis GO:0019725 252 0.017
reproductive process GO:0022414 372 0.017
regulation of anatomical structure size GO:0090066 135 0.016
positive regulation of developmental process GO:0051094 283 0.016
organic acid metabolic process GO:0006082 292 0.016
regulation of immune system process GO:0002682 123 0.016
protein transport GO:0015031 132 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
cellular response to mechanical stimulus GO:0071260 48 0.016
cellular response to extracellular stimulus GO:0031668 73 0.016
organic hydroxy compound metabolic process GO:1901615 115 0.016
regulation of transcription dna templated GO:0006355 374 0.016
response to temperature stimulus GO:0009266 94 0.016
response to cytokine GO:0034097 215 0.016
rho protein signal transduction GO:0007266 11 0.016
rna biosynthetic process GO:0032774 380 0.016
proteolysis GO:0006508 175 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
positive regulation of cell motility GO:2000147 97 0.015
cellular ketone metabolic process GO:0042180 51 0.015
homeostatic process GO:0042592 331 0.015
response to purine containing compound GO:0014074 126 0.015
secretion by cell GO:0032940 248 0.015
neuron differentiation GO:0030182 368 0.015
macromolecule localization GO:0033036 252 0.015
cellular component biogenesis GO:0044085 368 0.015
cell migration GO:0016477 197 0.015
response to monoamine GO:0071867 17 0.015
metal ion transport GO:0030001 289 0.015
regulation of cytokine production GO:0001817 56 0.015
response to fibroblast growth factor GO:0071774 29 0.015
positive regulation of cell migration GO:0030335 96 0.015
cellular response to nutrient GO:0031670 30 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
spindle organization GO:0007051 2 0.014
secretion GO:0046903 307 0.014
cellular response to platelet derived growth factor stimulus GO:0036120 7 0.014
motor neuron axon guidance GO:0008045 1 0.014
peptide cross linking GO:0018149 1 0.014
regulation of secretion by cell GO:1903530 208 0.014
regulation of cell migration GO:0030334 128 0.014
cellular response to alkaloid GO:0071312 25 0.014
neuron projection development GO:0031175 273 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
positive regulation of immune system process GO:0002684 90 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
regulation of transferase activity GO:0051338 123 0.013
lipid biosynthetic process GO:0008610 128 0.013
response to retinoic acid GO:0032526 63 0.013
kidney development GO:0001822 67 0.013
protein localization GO:0008104 191 0.013
tooth eruption GO:0044691 1 0.013
wound healing GO:0042060 122 0.013
localization of cell GO:0051674 202 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
regulation of neuron differentiation GO:0045664 208 0.013
cellular chemical homeostasis GO:0055082 247 0.013
locomotion GO:0040011 237 0.013
cellular response to oxygen levels GO:0071453 60 0.013
negative regulation of metabolic process GO:0009892 331 0.013
circulatory system development GO:0072359 134 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
negative regulation of cell death GO:0060548 229 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.012
negative regulation of nervous system development GO:0051961 79 0.012
growth GO:0040007 165 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
regulation of protein kinase activity GO:0045859 105 0.012
regulation of rna biosynthetic process GO:2001141 381 0.012
neuron death GO:0070997 127 0.012
regulation of locomotion GO:0040012 148 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
glomerulus development GO:0032835 10 0.012
response to nicotine GO:0035094 51 0.012
organophosphate metabolic process GO:0019637 370 0.012
positive regulation of response to external stimulus GO:0032103 51 0.012
brain development GO:0007420 247 0.012
response to catecholamine GO:0071869 16 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
head development GO:0060322 247 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
collagen fibril organization GO:0030199 1 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.011
developmental growth GO:0048589 100 0.011
cellular response to hypoxia GO:0071456 51 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
multi multicellular organism process GO:0044706 138 0.011
blood vessel morphogenesis GO:0048514 58 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.011
regulation of cell proliferation GO:0042127 359 0.011
response to epidermal growth factor GO:0070849 18 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
positive regulation of secretion GO:0051047 140 0.011
regulation of catalytic activity GO:0050790 304 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
sex differentiation GO:0007548 113 0.011
positive regulation of locomotion GO:0040017 102 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
response to activity GO:0014823 73 0.011
embryonic skeletal system development GO:0048706 3 0.011
ion homeostasis GO:0050801 212 0.011
cation homeostasis GO:0055080 195 0.011
glucose homeostasis GO:0042593 75 0.011
single organism behavior GO:0044708 130 0.010
protein phosphorylation GO:0006468 345 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
central nervous system development GO:0007417 311 0.010
lipid transport GO:0006869 61 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
response to corticosteroid GO:0031960 235 0.010
regulation of membrane potential GO:0042391 110 0.010
positive regulation of cellular component movement GO:0051272 102 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
single organism cell adhesion GO:0098602 46 0.010
positive regulation of cell communication GO:0010647 271 0.010
regulation of protein modification process GO:0031399 194 0.010
regulation of molecular function GO:0065009 398 0.010

Nid2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.059
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.043
eye disease DOID:5614 0 0.017
retinal disease DOID:5679 0 0.017
eye and adnexa disease DOID:1492 0 0.017
sensory system disease DOID:0050155 0 0.017
connective tissue disease DOID:65 0 0.013
retinal degeneration DOID:8466 0 0.013
bone development disease DOID:0080006 0 0.013
bone disease DOID:0080001 0 0.013
osteochondrodysplasia DOID:2256 0 0.010