Rattus norvegicus

114 known processes

Nkx2-1

NK2 homeobox 1

(Aliases: Titf1,TTF1)

Nkx2-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism reproductive process GO:0044702 297 0.356
Mouse
positive regulation of gene expression GO:0010628 244 0.353
sodium ion transport GO:0006814 82 0.324
regulation of molecular function GO:0065009 398 0.323
neuron differentiation GO:0030182 368 0.305
Mouse Fly
cellular component biogenesis GO:0044085 368 0.293
central nervous system development GO:0007417 311 0.274
Human Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.272
reproductive system development GO:0061458 128 0.241
Mouse
cellular response to stress GO:0033554 269 0.215
regulation of multicellular organismal development GO:2000026 376 0.208
Human
brain development GO:0007420 247 0.195
Human Mouse
reproductive process GO:0022414 372 0.176
positive regulation of biosynthetic process GO:0009891 319 0.176
transcription from rna polymerase ii promoter GO:0006366 252 0.171
gland development GO:0048732 155 0.171
Human Mouse
metal ion transport GO:0030001 289 0.159
transmembrane transport GO:0055085 412 0.159
regulation of anatomical structure size GO:0090066 135 0.156
rna metabolic process GO:0016070 406 0.156
regulation of neurogenesis GO:0050767 247 0.153
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.148
positive regulation of transport GO:0051050 245 0.142
locomotion GO:0040011 237 0.139
Human Mouse Worm
cellular response to abiotic stimulus GO:0071214 85 0.138
cation transport GO:0006812 382 0.134
behavior GO:0007610 205 0.133
positive regulation of cell development GO:0010720 176 0.131
neuron projection development GO:0031175 273 0.129
Mouse Fly
positive regulation of transcription dna templated GO:0045893 197 0.129
regulation of metal ion transport GO:0010959 118 0.125
multi multicellular organism process GO:0044706 138 0.125
intracellular signal transduction GO:0035556 314 0.120
response to external biotic stimulus GO:0043207 221 0.120
programmed cell death GO:0012501 392 0.119
reproductive structure development GO:0048608 128 0.116
Mouse
cell cell signaling GO:0007267 335 0.115
Mouse
regulation of cell development GO:0060284 263 0.112
Human
positive regulation of rna metabolic process GO:0051254 203 0.110
regulation of cell differentiation GO:0045595 320 0.109
Human
regulation of protein metabolic process GO:0051246 289 0.109
regulation of phosphate metabolic process GO:0019220 349 0.108
cell projection organization GO:0030030 302 0.107
Mouse Fly
response to estradiol GO:0032355 164 0.107
Rat
response to estrogen GO:0043627 232 0.106
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.105
positive regulation of rna biosynthetic process GO:1902680 197 0.104
aging GO:0007568 241 0.104
response to oxygen levels GO:0070482 265 0.103
positive regulation of protein metabolic process GO:0051247 178 0.102
nucleobase containing small molecule metabolic process GO:0055086 316 0.098
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.094
protein phosphorylation GO:0006468 345 0.094
positive regulation of signal transduction GO:0009967 175 0.094
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.093
anatomical structure morphogenesis GO:0009653 298 0.091
Human Mouse Fly
cellular component movement GO:0006928 248 0.089
Human Mouse
regulation of nervous system development GO:0051960 264 0.086
calcium ion transport GO:0006816 131 0.086
response to peptide hormone GO:0043434 278 0.085
response to cytokine GO:0034097 215 0.083
tissue development GO:0009888 252 0.083
Human Mouse Rat
rna biosynthetic process GO:0032774 380 0.083
regulation of ion transport GO:0043269 245 0.082
response to inorganic substance GO:0010035 377 0.082
positive regulation of phosphorylation GO:0042327 177 0.081
response to wounding GO:0009611 254 0.080
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.080
negative regulation of cellular biosynthetic process GO:0031327 161 0.080
Mouse Rat
positive regulation of developmental process GO:0051094 283 0.079
regulation of cellular component movement GO:0051270 150 0.077
Human
female pregnancy GO:0007565 122 0.077
positive regulation of nucleic acid templated transcription GO:1903508 197 0.076
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.076
Mouse Rat
carbohydrate derivative metabolic process GO:1901135 346 0.075
cellular response to endogenous stimulus GO:0071495 377 0.073
Human
regulation of nucleic acid templated transcription GO:1903506 380 0.071
regulation of transmembrane transport GO:0034762 122 0.069
epithelium development GO:0060429 96 0.068
Human Mouse
regulation of locomotion GO:0040012 148 0.068
Human
organophosphate metabolic process GO:0019637 370 0.067
Mouse
positive regulation of programmed cell death GO:0043068 157 0.067
transcription dna templated GO:0006351 377 0.067
regulation of cellular protein metabolic process GO:0032268 267 0.065
ion transmembrane transport GO:0034220 365 0.065
positive regulation of multicellular organismal process GO:0051240 387 0.065
cellular response to oxygen containing compound GO:1901701 386 0.064
response to hypoxia GO:0001666 231 0.064
circulatory system process GO:0003013 183 0.063
positive regulation of cellular biosynthetic process GO:0031328 295 0.063
positive regulation of cell differentiation GO:0045597 217 0.062
regulation of phosphorylation GO:0042325 248 0.060
regulation of neuron differentiation GO:0045664 208 0.059
cell migration GO:0016477 197 0.059
Human Mouse
regulation of kinase activity GO:0043549 117 0.059
reproduction GO:0000003 245 0.058
Worm
inorganic cation transmembrane transport GO:0098662 202 0.058
regulation of cell proliferation GO:0042127 359 0.058
positive regulation of molecular function GO:0044093 230 0.057
response to ketone GO:1901654 182 0.057
Rat
regulation of rna biosynthetic process GO:2001141 381 0.056
regulation of purine nucleotide metabolic process GO:1900542 115 0.055
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.055
Mouse Rat
chemotaxis GO:0006935 66 0.055
Mouse
positive regulation of transferase activity GO:0051347 81 0.055
response to decreased oxygen levels GO:0036293 237 0.054
apoptotic process GO:0006915 381 0.054
muscle contraction GO:0006936 88 0.054
circadian rhythm GO:0007623 88 0.054
chemical homeostasis GO:0048878 292 0.053
regulation of response to stress GO:0080134 126 0.053
regulation of secretion GO:0051046 224 0.053
single organism behavior GO:0044708 130 0.052
response to carbohydrate GO:0009743 183 0.052
Rat
cardiovascular system development GO:0072358 134 0.052
Rat
multi organism reproductive process GO:0044703 262 0.051
response to toxic substance GO:0009636 133 0.051
developmental process involved in reproduction GO:0003006 159 0.051
positive regulation of protein modification process GO:0031401 142 0.050
response to peptide GO:1901652 292 0.050
regulation of membrane repolarization GO:0060306 1 0.050
regulation of catalytic activity GO:0050790 304 0.048
purine nucleotide metabolic process GO:0006163 229 0.048
protein complex subunit organization GO:0071822 302 0.048
heart contraction GO:0060047 57 0.048
cellular response to organic cyclic compound GO:0071407 202 0.047
regulation of mapk cascade GO:0043408 116 0.047
regulation of phosphorus metabolic process GO:0051174 349 0.047
defense response GO:0006952 194 0.047
positive regulation of catalytic activity GO:0043085 184 0.046
muscle structure development GO:0061061 87 0.046
Rat
vascular process in circulatory system GO:0003018 96 0.045
regulation of hormone levels GO:0010817 187 0.045
negative regulation of cell death GO:0060548 229 0.045
negative regulation of response to wounding GO:1903035 23 0.045
positive regulation of cell communication GO:0010647 271 0.045
sodium ion transmembrane transport GO:0035725 67 0.045
hormone secretion GO:0046879 115 0.045
hepaticobiliary system development GO:0061008 90 0.043
inorganic ion transmembrane transport GO:0098660 229 0.043
positive regulation of response to stimulus GO:0048584 285 0.042
inflammatory response GO:0006954 150 0.042
oxidation reduction process GO:0055114 304 0.042
regulation of growth GO:0040008 105 0.042
secretion by cell GO:0032940 248 0.041
ribose phosphate metabolic process GO:0019693 235 0.041
regulation of transcription dna templated GO:0006355 374 0.041
positive regulation of kinase activity GO:0033674 77 0.041
regulation of system process GO:0044057 208 0.041
response to monosaccharide GO:0034284 159 0.041
Rat
negative regulation of biosynthetic process GO:0009890 168 0.041
Mouse Rat
regulation of protein phosphorylation GO:0001932 183 0.040
regulation of muscle contraction GO:0006937 53 0.040
response to lipopolysaccharide GO:0032496 191 0.039
regulation of ion transmembrane transport GO:0034765 121 0.039
single organism biosynthetic process GO:0044711 342 0.038
response to other organism GO:0051707 220 0.038
rhythmic process GO:0048511 156 0.038
nitrogen compound transport GO:0071705 229 0.038
nucleic acid templated transcription GO:0097659 379 0.038
regulation of catabolic process GO:0009894 113 0.038
ribonucleotide metabolic process GO:0009259 231 0.038
negative regulation of transcription dna templated GO:0045892 116 0.038
Mouse Rat
negative regulation of rna metabolic process GO:0051253 123 0.037
Mouse Rat
regulation of signal transduction GO:0009966 318 0.037
Human
positive regulation of map kinase activity GO:0043406 46 0.037
regulation of heart rate GO:0002027 16 0.037
regulation of protein kinase activity GO:0045859 105 0.037
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.036
Human
macromolecular complex assembly GO:0065003 273 0.036
regeneration GO:0031099 163 0.036
tube development GO:0035295 89 0.036
Human Mouse
response to purine containing compound GO:0014074 126 0.036
regulation of anatomical structure morphogenesis GO:0022603 141 0.035
Human
regulation of blood vessel size GO:0050880 89 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
regulation of apoptotic process GO:0042981 335 0.035
cellular response to acid chemical GO:0071229 75 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
Mouse Rat
negative regulation of growth GO:0045926 37 0.034
purine ribonucleotide metabolic process GO:0009150 227 0.034
regulation of rna metabolic process GO:0051252 391 0.034
divalent metal ion transport GO:0070838 132 0.034
regulation of cellular component organization GO:0051128 368 0.034
Human
proteolysis GO:0006508 175 0.033
wound healing GO:0042060 122 0.033
nucleotide metabolic process GO:0009117 279 0.033
cellular response to organonitrogen compound GO:0071417 197 0.033
divalent inorganic cation transport GO:0072511 134 0.033
mapk cascade GO:0000165 140 0.032
regulation of transferase activity GO:0051338 123 0.032
negative regulation of metabolic process GO:0009892 331 0.032
Mouse Rat
positive regulation of signaling GO:0023056 270 0.031
cardiac conduction GO:0061337 2 0.031
macromolecule localization GO:0033036 252 0.031
regulation of cellular localization GO:0060341 263 0.031
regulation of blood circulation GO:1903522 110 0.031
cell projection morphogenesis GO:0048858 123 0.031
Mouse Fly
positive regulation of nervous system development GO:0051962 178 0.030
regulation of response to wounding GO:1903034 69 0.030
regulation of response to external stimulus GO:0032101 106 0.030
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.030
regulation of epithelial cell proliferation GO:0050678 49 0.030
morphogenesis of an epithelium GO:0002009 20 0.029
Human
response to oxidative stress GO:0006979 186 0.029
regulation of tube size GO:0035150 89 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
neuron death GO:0070997 127 0.029
sex differentiation GO:0007548 113 0.029
neurological system process GO:0050877 219 0.029
organ morphogenesis GO:0009887 75 0.029
Human Mouse
organelle organization GO:0006996 266 0.028
organic cyclic compound catabolic process GO:1901361 175 0.028
growth GO:0040007 165 0.028
positive regulation of neurogenesis GO:0050769 165 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.028
Mouse Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.028
feeding behavior GO:0007631 53 0.028
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.028
positive regulation of neuron differentiation GO:0045666 126 0.028
cell motility GO:0048870 202 0.027
Human Mouse
actin filament based process GO:0030029 86 0.027
response to nutrient GO:0007584 248 0.027
gonad development GO:0008406 104 0.027
Mouse
heart process GO:0003015 57 0.027
negative regulation of developmental process GO:0051093 125 0.027
Human
positive regulation of hydrolase activity GO:0051345 86 0.027
response to biotic stimulus GO:0009607 226 0.027
response to alkaloid GO:0043279 132 0.026
regulation of muscle system process GO:0090257 79 0.026
carbohydrate metabolic process GO:0005975 130 0.026
negative regulation of response to external stimulus GO:0032102 37 0.026
regulation of cell growth GO:0001558 85 0.026
anatomical structure formation involved in morphogenesis GO:0048646 83 0.026
Mouse
negative regulation of gene expression GO:0010629 199 0.026
Mouse Rat
head development GO:0060322 247 0.026
Human Mouse
response to molecule of bacterial origin GO:0002237 194 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
tissue morphogenesis GO:0048729 22 0.026
Human
cellular nitrogen compound catabolic process GO:0044270 163 0.025
regulation of heart contraction GO:0008016 48 0.025
endocytosis GO:0006897 84 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
Human
regulation of behavior GO:0050795 61 0.025
response to calcium ion GO:0051592 59 0.025
epithelial cell proliferation GO:0050673 54 0.024
positive regulation of cell death GO:0010942 184 0.024
developmental growth GO:0048589 100 0.024
dna metabolic process GO:0006259 96 0.024
regulation of cell projection organization GO:0031344 175 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
cell cycle GO:0007049 101 0.023
male gonad development GO:0008584 59 0.023
Mouse
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.023
cellular ketone metabolic process GO:0042180 51 0.023
blood circulation GO:0008015 183 0.023
regulation of secretion by cell GO:1903530 208 0.023
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
cellular catabolic process GO:0044248 295 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
Mouse Rat
purine containing compound catabolic process GO:0072523 138 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
Mouse Rat
negative regulation of response to stimulus GO:0048585 155 0.023
Human
regulation of programmed cell death GO:0043067 341 0.023
nucleoside metabolic process GO:0009116 179 0.023
cytosolic calcium ion homeostasis GO:0051480 140 0.022
male sex differentiation GO:0046661 64 0.022
Mouse
hormone transport GO:0009914 121 0.022
response to extracellular stimulus GO:0009991 380 0.022
membrane depolarization during action potential GO:0086010 1 0.022
cellular response to oxidative stress GO:0034599 76 0.022
response to radiation GO:0009314 137 0.022
ion homeostasis GO:0050801 212 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
Mouse Rat
response to reactive oxygen species GO:0000302 120 0.021
response to temperature stimulus GO:0009266 94 0.021
response to hyperoxia GO:0055093 45 0.021
steroid metabolic process GO:0008202 73 0.021
regulation of transporter activity GO:0032409 50 0.021
organic substance catabolic process GO:1901575 316 0.021
secretion GO:0046903 307 0.021
positive regulation of protein kinase activity GO:0045860 73 0.021
intracellular transport GO:0046907 185 0.021
vesicle mediated transport GO:0016192 181 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.021
Mouse Rat
regulation of cellular catabolic process GO:0031329 101 0.021
oxoacid metabolic process GO:0043436 290 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
organic hydroxy compound transport GO:0015850 77 0.020
organic acid metabolic process GO:0006082 292 0.020
catabolic process GO:0009056 351 0.020
regulation of map kinase activity GO:0043405 53 0.020
cellular lipid metabolic process GO:0044255 208 0.020
Mouse
small gtpase mediated signal transduction GO:0007264 36 0.020
regulation of hormone secretion GO:0046883 106 0.020
multicellular organism reproduction GO:0032504 233 0.020
cellular component morphogenesis GO:0032989 155 0.020
Human Mouse Fly
positive regulation of protein phosphorylation GO:0001934 135 0.020
synaptic transmission GO:0007268 235 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
regulation of stem cell differentiation GO:2000736 2 0.019
Human
cellular homeostasis GO:0019725 252 0.019
cyclic nucleotide metabolic process GO:0009187 80 0.019
organic acid transport GO:0015849 116 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
muscle organ development GO:0007517 50 0.019
regulation of body fluid levels GO:0050878 90 0.019
neuron projection morphogenesis GO:0048812 122 0.019
Mouse Fly
cellular response to cytokine stimulus GO:0071345 127 0.019
cell morphogenesis GO:0000902 142 0.019
Human Mouse Fly
phospholipid metabolic process GO:0006644 61 0.019
Mouse
homeostatic process GO:0042592 331 0.019
striated muscle contraction GO:0006941 44 0.019
regulation of transmembrane transporter activity GO:0022898 49 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
regulation of cellular component size GO:0032535 51 0.019
signal release GO:0023061 145 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
response to nutrient levels GO:0031667 370 0.018
response to insulin GO:0032868 133 0.018
learning or memory GO:0007611 90 0.018
response to corticosteroid GO:0031960 235 0.018
purine nucleoside triphosphate catabolic process GO:0009146 122 0.018
organ formation GO:0048645 3 0.017
hormone metabolic process GO:0042445 69 0.017
purine nucleotide biosynthetic process GO:0006164 83 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
protein complex assembly GO:0006461 263 0.017
cell cycle process GO:0022402 57 0.017
protein complex biogenesis GO:0070271 263 0.017
lipid metabolic process GO:0006629 283 0.017
Mouse
response to activity GO:0014823 73 0.017
response to metal ion GO:0010038 253 0.017
liver development GO:0001889 90 0.017
estrous cycle phase GO:0060206 15 0.017
smooth muscle cell proliferation GO:0048659 77 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
cell activation GO:0001775 97 0.017
single organism organelle organization GO:1902589 180 0.016
purine containing compound metabolic process GO:0072521 253 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
regulation of immune system process GO:0002682 123 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
intracellular receptor signaling pathway GO:0030522 35 0.016
cytoplasmic transport GO:0016482 115 0.016
negative regulation of signaling GO:0023057 157 0.016
Human
regulation of cell motility GO:2000145 131 0.016
Human
regulation of protein modification process GO:0031399 194 0.016
response to glucocorticoid GO:0051384 223 0.016
nucleotide biosynthetic process GO:0009165 98 0.016
vasoconstriction GO:0042310 54 0.016
aromatic compound catabolic process GO:0019439 168 0.016
forebrain development GO:0030900 98 0.016
Human Mouse
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.016
cell cell signaling involved in cell fate commitment GO:0045168 2 0.015
Mouse
regulation of cation channel activity GO:2001257 23 0.015
cellular response to hexose stimulus GO:0071331 65 0.015
negative regulation of organ growth GO:0046621 3 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
leukocyte activation GO:0045321 76 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.015
negative regulation of transport GO:0051051 136 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
positive regulation of mapk cascade GO:0043410 92 0.015
regulation of neuron death GO:1901214 115 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
gastrulation GO:0007369 2 0.015
cardiac muscle cell contraction GO:0086003 10 0.015
immune system process GO:0002376 204 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
neuron neuron synaptic transmission GO:0007270 60 0.014
single organism cellular localization GO:1902580 102 0.014
positive regulation of stress activated mapk cascade GO:0032874 17 0.014
single organism intracellular transport GO:1902582 166 0.014
regulation of hydrolase activity GO:0051336 143 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
response to antibiotic GO:0046677 39 0.014
muscle cell proliferation GO:0033002 84 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
response to ammonium ion GO:0060359 71 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
response to bacterium GO:0009617 200 0.014
calcium ion homeostasis GO:0055074 162 0.014
cation transmembrane transport GO:0098655 263 0.014
regulation of feeding behavior GO:0060259 14 0.014
positive regulation of blood circulation GO:1903524 65 0.014
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
multicellular organism growth GO:0035264 1 0.014
ras protein signal transduction GO:0007265 29 0.014
response to hexose GO:0009746 144 0.014
Rat
heart development GO:0007507 72 0.014
Rat
negative regulation of immune system process GO:0002683 39 0.014
negative regulation of neuron death GO:1901215 69 0.014
cell growth GO:0016049 104 0.014
nucleotide catabolic process GO:0009166 139 0.013
defecation GO:0030421 1 0.013
positive regulation of catabolic process GO:0009896 78 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
regulation of cell cycle GO:0051726 73 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
regulation of axon extension GO:0030516 24 0.013
protein tetramerization GO:0051262 38 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
regulation of nucleotide biosynthetic process GO:0030808 47 0.013
angiogenesis GO:0001525 53 0.013
regulation of peptide transport GO:0090087 87 0.013
salivary gland development GO:0007431 3 0.013
organophosphate catabolic process GO:0046434 148 0.013
cellular protein localization GO:0034613 122 0.013
epithelial cell differentiation GO:0030855 71 0.013
Mouse
rho protein signal transduction GO:0007266 11 0.012
ovulation cycle GO:0042698 67 0.012
positive regulation of heart rate GO:0010460 9 0.012
sexual reproduction GO:0019953 148 0.012
camp biosynthetic process GO:0006171 47 0.012
negative regulation of synaptic transmission dopaminergic GO:0032227 4 0.012
regulation of striated muscle tissue development GO:0016202 25 0.012
somatic stem cell maintenance GO:0035019 2 0.012
regulation of homotypic cell cell adhesion GO:0034110 4 0.012
protein maturation GO:0051604 68 0.012
muscle system process GO:0003012 115 0.012
positive regulation of camp biosynthetic process GO:0030819 28 0.012
artery smooth muscle contraction GO:0014824 4 0.012
camp metabolic process GO:0046058 63 0.012
digestive system development GO:0055123 41 0.012
response to glucose GO:0009749 136 0.012
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.012
establishment of protein localization GO:0045184 141 0.012
cellular component assembly GO:0022607 360 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
regulation of lipid biosynthetic process GO:0046890 38 0.012
sensory organ development GO:0007423 74 0.012
neurotransmitter gated ion channel clustering GO:0072578 3 0.012
cytoskeleton organization GO:0007010 111 0.012
protein oligomerization GO:0051259 191 0.012
regulation of intracellular transport GO:0032386 65 0.012
regulation of cell activation GO:0050865 50 0.012
negative regulation of secretion by cell GO:1903531 72 0.012
regulation of cardiac muscle tissue growth GO:0055021 12 0.012
regulation of developmental growth GO:0048638 45 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
response to retinoic acid GO:0032526 63 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
muscle tissue development GO:0060537 58 0.011
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.011
negative regulation of cell development GO:0010721 82 0.011
Human
gamma aminobutyric acid transport GO:0015812 8 0.011
embryonic appendage morphogenesis GO:0035113 4 0.011
regulation of camp biosynthetic process GO:0030817 38 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.011
positive regulation of growth GO:0045927 55 0.011
maternal process involved in female pregnancy GO:0060135 38 0.011
single organism membrane organization GO:0044802 74 0.011
macromolecule catabolic process GO:0009057 58 0.011
regulation of lymphocyte proliferation GO:0050670 26 0.011
cellular response to reactive oxygen species GO:0034614 55 0.011
immunoglobulin mediated immune response GO:0016064 4 0.011
positive regulation of secretion GO:0051047 140 0.011
neurotransmitter uptake GO:0001504 3 0.011
response to increased oxygen levels GO:0036296 45 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
regulation of ion transmembrane transporter activity GO:0032412 48 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
choline transport GO:0015871 4 0.010
mesoderm development GO:0007498 2 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
cell communication by chemical coupling GO:0010643 2 0.010
negative regulation of cell communication GO:0010648 158 0.010
Human
regulation of muscle tissue development GO:1901861 25 0.010
macromolecular complex subunit organization GO:0043933 339 0.010
response to cgmp GO:0070305 3 0.010
positive regulation of protein transport GO:0051222 41 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
membrane depolarization GO:0051899 32 0.010
regulation of protein transport GO:0051223 68 0.010
microtubule polymerization or depolymerization GO:0031109 13 0.010
regulation of immunoglobulin secretion GO:0051023 1 0.010
retinal ganglion cell axon guidance GO:0031290 1 0.010
saliva secretion GO:0046541 3 0.010
neuron apoptotic process GO:0051402 88 0.010
ribonucleoside metabolic process GO:0009119 174 0.010

Nkx2-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
cardiovascular system disease DOID:1287 0 0.020
musculoskeletal system disease DOID:17 0 0.017