Rattus norvegicus

108 known processes

Nkx2-5

NK2 transcription factor related, locus 5 (Drosophila)

(Aliases: Csx,Nkx2.5)

Nkx2-5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 242 0.560
cation transport GO:0006812 382 0.544
Mouse
response to other organism GO:0051707 220 0.521
Rat
cellular chemical homeostasis GO:0055082 247 0.374
circulatory system process GO:0003013 183 0.327
Mouse Rat
transmembrane transport GO:0055085 412 0.284
Mouse
response to biotic stimulus GO:0009607 226 0.277
Rat
metal ion transport GO:0030001 289 0.259
Mouse
negative regulation of cell death GO:0060548 229 0.250
Human Mouse
cellular component assembly GO:0022607 360 0.246
Mouse
cellular homeostasis GO:0019725 252 0.230
central nervous system development GO:0007417 311 0.230
positive regulation of phosphorus metabolic process GO:0010562 262 0.224
apoptotic process GO:0006915 381 0.223
Human Mouse
muscle contraction GO:0006936 88 0.220
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.213
cation homeostasis GO:0055080 195 0.212
positive regulation of biosynthetic process GO:0009891 319 0.209
Human Mouse Rat Worm
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.205
Human Mouse Rat Worm
heart process GO:0003015 57 0.200
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.194
carboxylic acid metabolic process GO:0019752 289 0.188
neurological system process GO:0050877 219 0.187
protein complex biogenesis GO:0070271 263 0.187
Mouse
homeostatic process GO:0042592 331 0.186
regulation of programmed cell death GO:0043067 341 0.185
Human Mouse
response to cytokine GO:0034097 215 0.184
programmed cell death GO:0012501 392 0.184
Human Mouse
response to external biotic stimulus GO:0043207 221 0.184
Rat
response to extracellular stimulus GO:0009991 380 0.183
potassium ion transport GO:0006813 97 0.183
cellular response to oxygen containing compound GO:1901701 386 0.183
organonitrogen compound catabolic process GO:1901565 179 0.178
nucleoside phosphate metabolic process GO:0006753 283 0.173
positive regulation of multicellular organismal process GO:0051240 387 0.170
Human Mouse
tissue development GO:0009888 252 0.170
blood circulation GO:0008015 183 0.166
Mouse Rat
regulation of rna metabolic process GO:0051252 391 0.165
head development GO:0060322 247 0.165
regulation of apoptotic process GO:0042981 335 0.164
Human Mouse
brain development GO:0007420 247 0.161
positive regulation of signaling GO:0023056 270 0.157
regulation of phosphorylation GO:0042325 248 0.156
cardiovascular system development GO:0072358 134 0.156
forebrain development GO:0030900 98 0.151
cellular ion homeostasis GO:0006873 184 0.150
heart development GO:0007507 72 0.148
cellular response to endogenous stimulus GO:0071495 377 0.147
female gonad development GO:0008585 53 0.145
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.142
Human Mouse Rat Worm
cellular response to organic cyclic compound GO:0071407 202 0.141
regulation of catalytic activity GO:0050790 304 0.140
response to bacterium GO:0009617 200 0.138
Rat
regulation of body fluid levels GO:0050878 90 0.138
cellular component biogenesis GO:0044085 368 0.138
Mouse
synaptic transmission GO:0007268 235 0.137
purine nucleoside metabolic process GO:0042278 169 0.137
transcription dna templated GO:0006351 377 0.136
positive regulation of developmental process GO:0051094 283 0.133
Human Mouse
female pregnancy GO:0007565 122 0.131
cardiac muscle contraction GO:0060048 27 0.131
Mouse
organic acid metabolic process GO:0006082 292 0.129
negative regulation of macromolecule metabolic process GO:0010605 260 0.129
actin filament based movement GO:0030048 16 0.126
telencephalon development GO:0021537 62 0.125
chemical homeostasis GO:0048878 292 0.125
regulation of purine nucleotide metabolic process GO:1900542 115 0.124
ion homeostasis GO:0050801 212 0.124
ribonucleoside triphosphate catabolic process GO:0009203 122 0.124
cyclic purine nucleotide metabolic process GO:0052652 62 0.124
positive regulation of cell communication GO:0010647 271 0.122
development of primary sexual characteristics GO:0045137 107 0.121
Rat
multicellular organism reproduction GO:0032504 233 0.121
negative regulation of cellular metabolic process GO:0031324 281 0.121
cell cell signaling GO:0007267 335 0.118
neuron differentiation GO:0030182 368 0.116
Human
response to glucocorticoid GO:0051384 223 0.115
multicellular organismal signaling GO:0035637 44 0.114
negative regulation of metabolic process GO:0009892 331 0.111
aging GO:0007568 241 0.111
regulation of system process GO:0044057 208 0.106
Mouse
positive regulation of cell differentiation GO:0045597 217 0.104
Human Mouse
nucleoside metabolic process GO:0009116 179 0.103
cellular response to hormone stimulus GO:0032870 247 0.103
single organism reproductive process GO:0044702 297 0.103
purine containing compound metabolic process GO:0072521 253 0.103
secretion GO:0046903 307 0.102
response to peptide hormone GO:0043434 278 0.101
response to decreased oxygen levels GO:0036293 237 0.101
response to peptide GO:1901652 292 0.100
calcium ion transport GO:0006816 131 0.099
Mouse
regulation of striated muscle contraction GO:0006942 21 0.099
Mouse
response to estrogen GO:0043627 232 0.098
negative regulation of cell proliferation GO:0008285 119 0.098
positive regulation of nervous system development GO:0051962 178 0.097
Human
cellular cation homeostasis GO:0030003 180 0.097
ion transmembrane transport GO:0034220 365 0.097
Mouse
cellular metal ion homeostasis GO:0006875 172 0.097
macromolecular complex assembly GO:0065003 273 0.096
Mouse
response to monosaccharide GO:0034284 159 0.096
Rat
regulation of behavior GO:0050795 61 0.096
positive regulation of peptide hormone secretion GO:0090277 50 0.095
nucleoside phosphate catabolic process GO:1901292 140 0.094
catecholamine transport GO:0051937 37 0.093
monoamine transport GO:0015844 43 0.093
reproductive system development GO:0061458 128 0.092
organophosphate metabolic process GO:0019637 370 0.092
negative regulation of phosphate metabolic process GO:0045936 80 0.091
reproductive process GO:0022414 372 0.091
Rat
negative regulation of programmed cell death GO:0043069 183 0.090
Human Mouse
regulation of ion transport GO:0043269 245 0.090
Mouse
nucleobase containing small molecule metabolic process GO:0055086 316 0.090
purine ribonucleoside metabolic process GO:0046128 168 0.089
response to nutrient levels GO:0031667 370 0.089
monovalent inorganic cation transport GO:0015672 172 0.089
Mouse
response to hexose GO:0009746 144 0.089
Rat
nitrogen compound transport GO:0071705 229 0.089
detection of visible light GO:0009584 3 0.088
sensory perception GO:0007600 101 0.087
reproduction GO:0000003 245 0.087
metal ion homeostasis GO:0055065 186 0.087
macromolecular complex subunit organization GO:0043933 339 0.087
Mouse
development of primary female sexual characteristics GO:0046545 56 0.085
Rat
response to histamine GO:0034776 3 0.084
sex differentiation GO:0007548 113 0.083
Rat
heterocycle catabolic process GO:0046700 167 0.083
cellular ketone metabolic process GO:0042180 51 0.083
purine nucleotide metabolic process GO:0006163 229 0.082
ovulation cycle GO:0042698 67 0.082
regulation of rna biosynthetic process GO:2001141 381 0.082
response to estradiol GO:0032355 164 0.082
regulation of nucleotide metabolic process GO:0006140 117 0.082
protein complex assembly GO:0006461 263 0.082
Mouse
purine ribonucleotide metabolic process GO:0009150 227 0.082
ribonucleoside metabolic process GO:0009119 174 0.081
nucleotide metabolic process GO:0009117 279 0.081
phototransduction visible light GO:0007603 2 0.080
nucleoside triphosphate catabolic process GO:0009143 123 0.080
positive regulation of molecular function GO:0044093 230 0.079
Mouse
organic hydroxy compound transport GO:0015850 77 0.079
response to molecule of bacterial origin GO:0002237 194 0.079
Rat
inflammatory response GO:0006954 150 0.079
rhythmic process GO:0048511 156 0.078
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.078
amine metabolic process GO:0009308 38 0.078
regulation of multicellular organismal development GO:2000026 376 0.077
Human Mouse
divalent inorganic cation transport GO:0072511 134 0.077
Mouse
positive regulation of phosphorylation GO:0042327 177 0.076
response to corticosteroid GO:0031960 235 0.076
response to hypoxia GO:0001666 231 0.073
reproductive structure development GO:0048608 128 0.071
protein complex subunit organization GO:0071822 302 0.071
Mouse
multi multicellular organism process GO:0044706 138 0.070
nucleoside catabolic process GO:0009164 126 0.070
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.069
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.068
striated muscle contraction GO:0006941 44 0.067
Mouse
positive regulation of hydrolase activity GO:0051345 86 0.066
regulation of protein phosphorylation GO:0001932 183 0.066
anion transport GO:0006820 178 0.066
regulation of molecular function GO:0065009 398 0.066
Mouse
purine containing compound catabolic process GO:0072523 138 0.065
behavior GO:0007610 205 0.065
Rat
regulation of cell proliferation GO:0042127 359 0.064
Mouse
negative regulation of phosphorus metabolic process GO:0010563 80 0.064
regulation of muscle system process GO:0090257 79 0.064
Mouse
regulation of membrane potential GO:0042391 110 0.064
purine ribonucleoside catabolic process GO:0046130 124 0.064
ribose phosphate biosynthetic process GO:0046390 87 0.063
ribonucleotide catabolic process GO:0009261 136 0.063
regulation of cellular component organization GO:0051128 368 0.063
Mouse
response to light stimulus GO:0009416 52 0.063
calcium ion homeostasis GO:0055074 162 0.062
intracellular signal transduction GO:0035556 314 0.062
guanosine containing compound metabolic process GO:1901068 74 0.062
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.060
carbohydrate derivative catabolic process GO:1901136 147 0.060
organophosphate catabolic process GO:0046434 148 0.060
response to radiation GO:0009314 137 0.059
cellular response to lipid GO:0071396 201 0.059
defense response GO:0006952 194 0.059
positive regulation of synaptic transmission GO:0050806 62 0.059
ribose phosphate metabolic process GO:0019693 235 0.059
ribonucleotide metabolic process GO:0009259 231 0.059
cytosolic calcium ion homeostasis GO:0051480 140 0.058
protein oligomerization GO:0051259 191 0.058
cellular response to stress GO:0033554 269 0.058
regulation of growth GO:0040008 105 0.058
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.058
Human Mouse Rat Worm
rna metabolic process GO:0016070 406 0.058
regulation of cellular catabolic process GO:0031329 101 0.057
negative regulation of apoptotic process GO:0043066 181 0.057
Human Mouse
choline transport GO:0015871 4 0.056
regulation of smooth muscle cell proliferation GO:0048660 75 0.056
ribonucleoside catabolic process GO:0042454 126 0.056
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.056
single organism biosynthetic process GO:0044711 342 0.056
response to purine containing compound GO:0014074 126 0.056
hormone biosynthetic process GO:0042446 25 0.056
cellular amine metabolic process GO:0044106 38 0.055
regulation of cell differentiation GO:0045595 320 0.055
Human Mouse
cell activation GO:0001775 97 0.055
anatomical structure morphogenesis GO:0009653 298 0.054
Human Mouse
divalent inorganic cation homeostasis GO:0072507 165 0.054
response to lipopolysaccharide GO:0032496 191 0.053
Rat
regulation of cellular localization GO:0060341 263 0.053
aromatic compound catabolic process GO:0019439 168 0.053
small gtpase mediated signal transduction GO:0007264 36 0.052
response to ethanol GO:0045471 162 0.052
Rat
synaptic transmission glycinergic GO:0060012 2 0.052
response to ketone GO:1901654 182 0.052
Rat
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.051
nucleoside triphosphate metabolic process GO:0009141 144 0.051
inorganic ion transmembrane transport GO:0098660 229 0.051
Mouse
organophosphate biosynthetic process GO:0090407 143 0.051
response to camp GO:0051591 91 0.051
negative regulation of transport GO:0051051 136 0.050
purine nucleotide catabolic process GO:0006195 136 0.050
regulation of cell development GO:0060284 263 0.049
Human
divalent metal ion transport GO:0070838 132 0.049
Mouse
gtp metabolic process GO:0046039 72 0.048
organonitrogen compound biosynthetic process GO:1901566 167 0.048
regulation of catabolic process GO:0009894 113 0.048
nucleotide catabolic process GO:0009166 139 0.048
oxoacid metabolic process GO:0043436 290 0.048
purine ribonucleotide biosynthetic process GO:0009152 81 0.047
response to wounding GO:0009611 254 0.047
regulation of response to external stimulus GO:0032101 106 0.047
organic substance catabolic process GO:1901575 316 0.047
cellular divalent inorganic cation homeostasis GO:0072503 162 0.047
macromolecule localization GO:0033036 252 0.047
steroid metabolic process GO:0008202 73 0.046
positive regulation of protein metabolic process GO:0051247 178 0.046
regulation of nucleotide catabolic process GO:0030811 65 0.046
rna biosynthetic process GO:0032774 380 0.046
neuron development GO:0048666 286 0.046
cellular response to organonitrogen compound GO:0071417 197 0.046
response to mineralocorticoid GO:0051385 49 0.045
nucleobase containing compound catabolic process GO:0034655 152 0.045
purine nucleoside triphosphate catabolic process GO:0009146 122 0.045
ventricular cardiac muscle cell action potential GO:0086005 2 0.045
organic anion transport GO:0015711 132 0.044
guanosine containing compound catabolic process GO:1901069 71 0.044
purine nucleoside triphosphate metabolic process GO:0009144 141 0.044
muscle cell apoptotic process GO:0010657 30 0.044
Human Mouse
glycosyl compound catabolic process GO:1901658 126 0.043
response to vitamin e GO:0033197 24 0.043
cell projection organization GO:0030030 302 0.043
immune system process GO:0002376 204 0.043
Human Mouse
regulation of cellular amine metabolic process GO:0033238 8 0.043
response to organophosphorus GO:0046683 102 0.043
long term synaptic potentiation GO:0060291 21 0.043
female sex differentiation GO:0046660 59 0.043
Rat
protein phosphorylation GO:0006468 345 0.042
cytoskeleton organization GO:0007010 111 0.042
Mouse
multicellular organismal reproductive process GO:0048609 233 0.042
response to hydrogen peroxide GO:0042542 89 0.041
positive regulation of cell death GO:0010942 184 0.041
cellular calcium ion homeostasis GO:0006874 160 0.041
cellular catabolic process GO:0044248 295 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.040
positive regulation of catalytic activity GO:0043085 184 0.040
cellular amino acid metabolic process GO:0006520 107 0.040
organic hydroxy compound biosynthetic process GO:1901617 51 0.040
cell type specific apoptotic process GO:0097285 134 0.040
Human Mouse
negative regulation of biosynthetic process GO:0009890 168 0.039
smooth muscle cell proliferation GO:0048659 77 0.039
cellular response to external stimulus GO:0071496 118 0.039
response to nutrient GO:0007584 248 0.039
positive regulation of apoptotic process GO:0043065 154 0.039
muscle tissue development GO:0060537 58 0.039
ras protein signal transduction GO:0007265 29 0.039
regulation of hormone levels GO:0010817 187 0.038
ribonucleotide biosynthetic process GO:0009260 85 0.038
carbohydrate derivative metabolic process GO:1901135 346 0.038
detection of external stimulus GO:0009581 13 0.038
regulation of blood pressure GO:0008217 83 0.038
Rat
positive regulation of neurogenesis GO:0050769 165 0.037
Human
regulation of blood vessel size GO:0050880 89 0.037
cellular response to nitrogen compound GO:1901699 210 0.037
regulation of response to stress GO:0080134 126 0.036
actin mediated cell contraction GO:0070252 12 0.036
lipid metabolic process GO:0006629 283 0.036
transmission of nerve impulse GO:0019226 42 0.036
regulation of hydrolase activity GO:0051336 143 0.035
negative regulation of gene expression GO:0010629 199 0.035
glycosyl compound metabolic process GO:1901657 182 0.035
regulation of transcription dna templated GO:0006355 374 0.035
neuron projection development GO:0031175 273 0.034
negative regulation of signaling GO:0023057 157 0.034
Mouse
carbohydrate derivative biosynthetic process GO:1901137 124 0.034
positive regulation of intracellular signal transduction GO:1902533 138 0.033
response to glucose GO:0009749 136 0.033
Rat
multi organism reproductive process GO:0044703 262 0.033
purine nucleoside catabolic process GO:0006152 124 0.033
response to starvation GO:0042594 59 0.032
negative regulation of molecular function GO:0044092 133 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
carboxylic acid transport GO:0046942 115 0.032
vascular process in circulatory system GO:0003018 96 0.032
negative regulation of response to stimulus GO:0048585 155 0.032
Mouse
purine ribonucleotide catabolic process GO:0009154 136 0.032
regulation of transmembrane transport GO:0034762 122 0.032
Mouse
cellular lipid metabolic process GO:0044255 208 0.032
smooth muscle contraction GO:0006939 37 0.032
immune response GO:0006955 104 0.031
protein heterooligomerization GO:0051291 89 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
Human Mouse Rat Worm
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
regulation of neuron death GO:1901214 115 0.031
single organism catabolic process GO:0044712 283 0.031
neuron neuron synaptic transmission GO:0007270 60 0.031
gland development GO:0048732 155 0.030
Human Mouse
cyclic nucleotide metabolic process GO:0009187 80 0.030
response to metal ion GO:0010038 253 0.030
neuronal action potential GO:0019228 35 0.030
camp metabolic process GO:0046058 63 0.030
gonad development GO:0008406 104 0.030
nucleic acid templated transcription GO:0097659 379 0.030
positive regulation of signal transduction GO:0009967 175 0.030
inflammatory response to antigenic stimulus GO:0002437 18 0.030
regulation of potassium ion transport GO:0043266 29 0.030
detection of stimulus GO:0051606 24 0.030
negative regulation of cell communication GO:0010648 158 0.029
Mouse
regulation of secretion by cell GO:1903530 208 0.029
sodium ion transport GO:0006814 82 0.029
Mouse
positive regulation of response to stimulus GO:0048584 285 0.029
positive regulation of programmed cell death GO:0043068 157 0.029
regulation of purine nucleotide catabolic process GO:0033121 65 0.029
signal release GO:0023061 145 0.028
negative regulation of ion transport GO:0043271 51 0.028
positive regulation of immune system process GO:0002684 90 0.028
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.028
c21 steroid hormone biosynthetic process GO:0006700 10 0.028
sensory perception of pain GO:0019233 73 0.028
actin filament based process GO:0030029 86 0.028
Mouse
positive regulation of protein modification process GO:0031401 142 0.028
small molecule biosynthetic process GO:0044283 124 0.027
regulation of camp metabolic process GO:0030814 43 0.027
regulation of sodium ion transport GO:0002028 21 0.027
Mouse
regulation of nucleoside metabolic process GO:0009118 66 0.027
response to interleukin 1 GO:0070555 55 0.027
cellular response to glucocorticoid stimulus GO:0071385 68 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
catecholamine secretion GO:0050432 33 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
anion transmembrane transport GO:0098656 77 0.027
monocarboxylic acid transport GO:0015718 52 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.027
learning or memory GO:0007611 90 0.027
regulation of metal ion transport GO:0010959 118 0.026
Mouse
detection of abiotic stimulus GO:0009582 13 0.026
positive regulation of nucleotide metabolic process GO:0045981 91 0.026
catabolic process GO:0009056 351 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
epithelium development GO:0060429 96 0.026
Mouse
positive regulation of ion transport GO:0043270 94 0.026
Mouse
purine containing compound biosynthetic process GO:0072522 85 0.026
regulation of signal transduction GO:0009966 318 0.025
Mouse
negative regulation of cellular protein metabolic process GO:0032269 106 0.025
glucose homeostasis GO:0042593 75 0.025
response to insulin GO:0032868 133 0.025
glucocorticoid metabolic process GO:0008211 7 0.025
ribonucleoside triphosphate metabolic process GO:0009199 141 0.025
positive regulation of cell development GO:0010720 176 0.025
Human
regulation of nervous system development GO:0051960 264 0.025
Human
oxidation reduction process GO:0055114 304 0.025
regulation of defecation GO:2000292 1 0.025
muscle system process GO:0003012 115 0.025
Mouse
cellular response to ammonium ion GO:0071242 17 0.025
cardiac muscle cell contraction GO:0086003 10 0.024
vesicle mediated transport GO:0016192 181 0.024
Worm
lipid biosynthetic process GO:0008610 128 0.024
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.024
regulation of cellular component movement GO:0051270 150 0.024
steroid biosynthetic process GO:0006694 48 0.024
circulatory system development GO:0072359 134 0.024
amide transport GO:0042886 105 0.024
positive regulation of cellular catabolic process GO:0031331 71 0.024
response to oxidative stress GO:0006979 186 0.023
organic hydroxy compound metabolic process GO:1901615 115 0.023
regulation of muscle cell apoptotic process GO:0010660 26 0.023
Human Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.023
organic cyclic compound catabolic process GO:1901361 175 0.023
response to alkaloid GO:0043279 132 0.023
regulation of gtp catabolic process GO:0033124 58 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
regulation of actin filament based movement GO:1903115 12 0.023
regulation of camp biosynthetic process GO:0030817 38 0.023
developmental process involved in reproduction GO:0003006 159 0.023
Rat
striated muscle tissue development GO:0014706 58 0.023
nucleoside phosphate biosynthetic process GO:1901293 102 0.023
cellular response to abiotic stimulus GO:0071214 85 0.023
antibiotic transport GO:0042891 2 0.022
negative regulation of muscle cell apoptotic process GO:0010656 21 0.022
Human Mouse
gtp catabolic process GO:0006184 71 0.022
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 24 0.022
regulation of gtpase activity GO:0043087 57 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.022
synaptic transmission gabaergic GO:0051932 22 0.022
monocarboxylic acid metabolic process GO:0032787 152 0.022
second messenger mediated signaling GO:0019932 51 0.022
body fluid secretion GO:0007589 41 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
response to vitamin GO:0033273 131 0.022
regulation of secretion GO:0051046 224 0.022
positive regulation of homeostatic process GO:0032846 49 0.022
exploration behavior GO:0035640 1 0.022
organic acid transport GO:0015849 116 0.021
ensheathment of neurons GO:0007272 40 0.021
axis specification GO:0009798 4 0.021
amino acid transport GO:0006865 70 0.021
response to mechanical stimulus GO:0009612 134 0.021
regulation of blood circulation GO:1903522 110 0.021
Mouse
regulation of membrane repolarization GO:0060306 1 0.021
camp biosynthetic process GO:0006171 47 0.021
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.021
regulation of anatomical structure size GO:0090066 135 0.021
intracellular transport GO:0046907 185 0.021
organelle organization GO:0006996 266 0.021
Mouse
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.021
neuromuscular process GO:0050905 2 0.021
lipid transport GO:0006869 61 0.021
cytoplasmic transport GO:0016482 115 0.021
regulation of developmental growth GO:0048638 45 0.020
Mouse
tube development GO:0035295 89 0.020
Mouse Worm
regulation of muscle contraction GO:0006937 53 0.020
Mouse
regulation of erk1 and erk2 cascade GO:0070372 41 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
negative regulation of transporter activity GO:0032410 13 0.020
hormone metabolic process GO:0042445 69 0.020
synapse organization GO:0050808 46 0.020
ovulation cycle process GO:0022602 50 0.020
heart contraction GO:0060047 57 0.020
Mouse
cellular nitrogen compound catabolic process GO:0044270 163 0.020
positive regulation of phagocytosis engulfment GO:0060100 4 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
positive regulation of nucleoside metabolic process GO:0045979 55 0.020
regulation of response to wounding GO:1903034 69 0.020
regulation of synaptic transmission GO:0050804 141 0.020
lipid localization GO:0010876 62 0.020
defecation GO:0030421 1 0.020
cellular response to hexose stimulus GO:0071331 65 0.020
cellular protein localization GO:0034613 122 0.020
positive regulation of mapk cascade GO:0043410 92 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
secretion by tissue GO:0032941 37 0.020
regulation of neurogenesis GO:0050767 247 0.019
Human
negative regulation of response to wounding GO:1903035 23 0.019
regulation of synaptic plasticity GO:0048167 70 0.019
immune system development GO:0002520 41 0.019
Human Mouse
cyclic nucleotide biosynthetic process GO:0009190 63 0.019
peptidyl amino acid modification GO:0018193 126 0.019
regulation of calcium ion transport GO:0051924 77 0.019
Mouse
alcohol biosynthetic process GO:0046165 38 0.019
organ morphogenesis GO:0009887 75 0.019
Human Mouse
regulation of protein modification process GO:0031399 194 0.019
positive regulation of growth GO:0045927 55 0.018
gastric motility GO:0035482 3 0.018
muscle structure development GO:0061061 87 0.018
alcohol metabolic process GO:0006066 77 0.018
signal transduction by phosphorylation GO:0023014 144 0.018
positive regulation of catabolic process GO:0009896 78 0.018
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.018
fatty acid metabolic process GO:0006631 99 0.018
action potential GO:0001508 54 0.017
response to calcium ion GO:0051592 59 0.017
regulation of immune system process GO:0002682 123 0.017
embryonic pattern specification GO:0009880 1 0.017
excretion GO:0007588 24 0.017
single organism intracellular transport GO:1902582 166 0.017
positive regulation of gtpase activity GO:0043547 47 0.017
response to toxic substance GO:0009636 133 0.017
cellular response to oxygen levels GO:0071453 60 0.017
response to growth factor GO:0070848 189 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
peptidyl tyrosine modification GO:0018212 72 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
establishment of protein localization GO:0045184 141 0.017
response to nicotine GO:0035094 51 0.016
organ regeneration GO:0031100 101 0.016
positive regulation of nucleotide catabolic process GO:0030813 53 0.016
cellular component movement GO:0006928 248 0.016
androgen metabolic process GO:0008209 14 0.016
calcium mediated signaling GO:0019722 23 0.016

Nkx2-5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
long qt syndrome DOID:2843 0 0.101
disease of anatomical entity DOID:7 0 0.085
Human
nervous system disease DOID:863 0 0.085
sensory system disease DOID:0050155 0 0.067
eye and adnexa disease DOID:1492 0 0.067
eye disease DOID:5614 0 0.067
muscular disease DOID:0080000 0 0.019
musculoskeletal system disease DOID:17 0 0.019
muscle tissue disease DOID:66 0 0.019
myopathy DOID:423 0 0.018
central nervous system disease DOID:331 0 0.017